| Utestående aktier | 97,986,634 shares |
| Insideraktier | 2 135 903 shares |
| Insynsägande | 2,18 % |
| Totalt antal insynspersoner | 41 |
Insider Sentiment Score
Insider sentiment score hittar de företag som köps av foretagsinsynspersoner.
Det är resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av insiderackumulation. Poängmodellen använder en kombination av nettoantalet insiders som köpt de föregående 90 dagarna, det totala antalet aktier som köpts i procent av aktiekapitalet och det totala antalet aktier som ägs av insiders. Siffran sträcker sig från 0 till 100, med högre siffror som indikerar en högre nivå av ackumulering för sina kamrater, och 50 är genomsnittet.
Uppdateringsfrekvens: Dagligen
Se Insiders Top Picks, som ger en lista över företag med högsta insiderackumulation.
Office Sentiment Score
Officersentiment Score hittar företag som köps av Corporate Officers.
Per definition Corporate Officers är Corporate Insiders, men till skillnad från vissa av de andra Insiders (10 % aktieägare och styrelseledamöter), arbetar ämbetsmän för företaget dagligen och de använder sina egna pengar när de handlar . (10 % aktieägare och styrelseledamöter är ofta fondförvaltare som förvaltar andras pengar.) Som sådan är insideraffärer som görs av tjänstemän mycket mer betydelsefulla och bör behandlas på lämpligt sätt.
Liksom Insider Sentiment Score är Officer Sentiment Score resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av officersackumulering.
Uppdateringsfrekvens: Dagligen
Se insiderns bästa val, vilket ger en lista över företag med högsta insider sentiment.
Viktiga insidernyckeltal
Denna kort visar hur företaget rankas längs olika insidernyckeltal. Procenttilrankningen visar hur detta företag jämförs med andra företag på USA-marknaden. Högre rankingar indikerar bättre situationer.
Till exempel anses det allmänt att insiderköp är en positiv indikator, så företag med mer insiderköp skulle rankas högre än företag med mindre insiderköp (eller til och med insiderförsäljning).
Procent av flytande köpta av insiders (ranking)
0.000 %( )
560 out of 11219Procentandelen av aktier köpta av insiders är det totala antalet aktier som köpts av insiders minus det totala antalet aktier som sålts av insiders under de senaste 90 dagarna, dividerat med det totala antalet aktier och multiplicerat med 100.
Insiderhandelsdiagram
aTyr Pharma, Inc. insideraffärer visas i följande diagram. Insiders är tjänstemän, styrelseledamöter eller betydande investerare i ett företag. I allmänhet är det i allmänhet olagligt för insiders att göra affärer i sina företag baserat på väsentlig, icke-offentlig information. Detta betyder inte att det är olagligt för dem att göra några affärer i sina egna företag. De måste dock rapportera alla affärer till SEC via ett formulär 4.
Insiderlista och lönsamhetsstatistik
Den här tabellen visar listan över kända insiders och genereras automatiskt från anmälningar som avslöjas till SEC. Förutom namnen, den senaste titeln och direktören, tjänstemannen eller ägarbeteckningen på 10 %, tillhandahåller vi de senaste avslöjade innehaven. Dessutom, när det är möjligt tillhandahåller vi insiderns historiska handelsresultat. Det historiska handelsresultatet är ett vägt genomsnitt av resultatet för faktiska köptransaktioner på den öppna marknaden som insidern gjort. För mer information om hur detta beräknas, titta på detta YouTube-webinarium.
See our leaderboard of most profitable insider traders.
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
|
Srinivas Akkaraju
10% Owner -
|
1 866 126 | 133 295 | |
|
Alta Partners VIII, L.P.
10% Owner -
|
1 778 064 | 127 005 | |
| Ashraf Amanullah See Remarks - [O] | 26 264 | 1 876 | |
| Ashlock Melissa A. See Remarks - [O] | 136 328 | 9 738 | |
|
James C Blair
Director, 10% Owner -
[D]
|
20 000 | 129 130 | |
| Kelly Blackburn See Remarks - [O] | 558 | 40 | |
| Stan Blackburn - | 23 908 | 1 708 | |
| John T Blake Senior Vice President, Finance - [O] | 1 932 | 138 | |
| Jill Marie Broadfoot Chief Financial Officer - [O] | 31 763 | 31 763 | |
|
Chp Ii Lp
10% Owner -
|
1 758 158 | 125 583 | |
| John K Clarke Director - [D] | 19 797 | 19 797 | |
| Frederic Chereau COO & President - [O] | 25 734 | 1 838 | |
| Chrzanowski Holly D. See Remarks - [O] | 3 770 | 269 |
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
| Timothy P Coughlin Director - [D] | 56 000 | 56 000 | |
| Andrew Cubitt | 25 000 | ||
|
Associates Domain
10% Owner -
|
18 858 | 1 347 | |
|
DP VIII Associates, L.P.
10% Owner -
|
13 414 | 958 | |
|
Domain Partners VIII, L.P.
10% Owner -
|
1 807 820 | 129 130 | |
|
EcoR1 Capital Fund Qualified, L.P.
10% Owner -
|
0 | 0 | |
| Kathryn E Falberg Director - [D] | 25 144 | 1 796 | |
|
James E Flynn
10% Owner -
|
255 764 | 18 269 | |
| Mark Alan Goldberg | 20 000 | ||
| Marcy Graham | 12 023 | ||
| Jane A Gross Director - [D] | 9 750 | 9 750 | |
| Hatfield Jeffrey S. | 1 428 | ||
|
Kamdar Kim P.
10% Owner -
|
18 858 | 1 347 | |
| David John King | 150 000 |
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
| Nancy Krueger General Counsel - [O] | 26 555 | 26 555 | |
| Svetlana Lucas Director - [D] | 6 000 | 6 000 | |
| John Mendlein Director - [D] | 615 382 | 43 956 | |
| Grove Matsuoka See Remarks - [O] | 12 412 | 887 | |
| McKew John C. | 40 000 | ||
| Amir Nashat Director - [D] | 17 638 | 1 260 | |
|
Polaris Venture Management Co. V, L.L.C.
10% Owner -
|
17 638 | 1 260 | |
| Fred Ramsdell | 5 393 | ||
| Ravindran Sanuj K. | 40 000 | ||
| Paul Schimmel Director - [D] | 1 101 056 | 1 101 056 | |
| Sanjay Shukla President and CEO, Director - [D] [O] | 146 923 | 146 923 | |
|
Sofinnova Venture Partners IX, L.P.
10% Owner -
|
1 866 126 | 133 295 | |
| Weiner David M. Chief Medical Officer - [O] | 10 056 | 718 | |
| Sara Zaknoen Director - [D] | 6 000 | 6 000 |
Report errors via our new Insider Auditing Tool
Track Records av insiderköp - Kortsiktig vinstanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i ATYR / aTyr Pharma, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste köpen på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Track Records av insiderförsäljning - Kortsiktig förlustanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i ATYR / aTyr Pharma, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste försäljningarna på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Transaktionshistorik
Klicka på länkikonen för att se hela transaktionshistoriken. Transaktioner som rapporteras som en del av en automatisk handelsplan 10b5-1 kommer att ha ett X i kolumnen markerad 10b-5.
| Fil datum |
Handel datum |
Schema | Insider | Ticker | Värdepappertitel | Kod | Direkta | Utövningspris | Enhet pris |
Enheter ändrad |
Värde ändrad (1K) |
Kvarvarande Optioner |
Kvarvarande Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-03-17 | 2025-03-17 | 4 | Gross Jane A | ATYR | Common Stock | D | 4,0000 | 3 750 | 15 | 9 750 | ||||
| 2025-02-04 | 2025-02-03 | 4 | Shukla Sanjay | ATYR | Common Stock | D | 10 375 | 146 923 | ||||||
| 2025-02-04 | 2025-02-04 | 4 | Broadfoot Jill Marie | ATYR | Common Stock | D | 3,7800 | −1 254 | −5 | 31 763 | ||||
| 2025-02-04 | 2025-02-03 | 4 | Broadfoot Jill Marie | ATYR | Common Stock | D | 3 750 | 33 017 | ||||||
| 2025-02-04 | 2025-02-04 | 4 | Krueger Nancy | ATYR | Common Stock | D | 3,7800 | −899 | −3 | 26 555 | ||||
| 2025-02-04 | 2025-02-03 | 4 | Krueger Nancy | ATYR | Common Stock | D | 2 687 | 27 454 | ||||||
| 2024-07-24 | 2024-07-24 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | 1,9319 | 52 300 | 101 | 413 023 | ||||
| 2024-07-24 | 2024-07-23 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | 1,8163 | 6 648 | 12 | 360 723 | ||||
| 2024-07-24 | 2024-07-22 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | 1,7417 | 41 052 | 72 | 354 075 | ||||
| 2024-06-06 | 2024-06-05 | 4 | Krueger Nancy | ATYR | Common Stock | D | 1,8552 | 5 000 | 9 | 22 267 | ||||
| 2024-06-03 | 2024-05-30 | 4 | Coughlin Timothy P | LIFE | Common Stock | I | 1,7500 | 50 000 | 88 | 56 000 | ||||
| 2024-06-03 | 2024-05-31 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | 1,7900 | 5 000 | 9 | 27 960 | ||||
| 2024-06-03 | 2024-05-31 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 1,8070 | 20 000 | 36 | 136 548 | ||||
| 2024-02-06 | 2024-02-05 | 4 | Shukla Sanjay | LIFE | Common stock | D | 10 375 | 116 548 | ||||||
| 2024-02-06 | 2024-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 1,6900 | −1 590 | −3 | 20 821 | ||||
| 2024-02-06 | 2024-02-05 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 3 750 | 22 411 | ||||||
| 2024-02-06 | 2024-02-05 | 4 | Krueger Nancy | LIFE | Common stock | D | 2 688 | 14 767 | ||||||
| 2023-12-12 | 2023-12-12 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 1,1780 | 12 000 | 14 | 106 173 | ||||
| 2023-12-12 | 2023-12-11 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 1,1700 | 3 000 | 4 | 94 173 | ||||
| 2023-11-13 | 2023-11-13 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 1,1110 | 13 578 | 15 | 91 173 | ||||
| 2023-11-13 | 2023-11-10 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 1,1380 | 1 422 | 2 | 77 595 | ||||
| 2023-08-01 | 2023-07-28 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 2,0149 | 15 000 | 30 | 76 173 | ||||
| 2023-05-19 | 2023-05-17 | 4 | Coughlin Timothy P | LIFE | Common Stock | I | 6 000 | 6 000 | ||||||
| 2023-05-19 | 2023-05-17 | 4 | Coughlin Timothy P | LIFE | Common Stock | D | −6 000 | 0 | ||||||
| 2023-05-11 | 2023-05-10 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,2500 | 200 000 | 450 | 313 023 | ||||
| 2023-04-28 | 2023-04-26 | 4 | CLARKE JOHN K | LIFE | Common Stock | D | 6 000 | 19 797 | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Coughlin Timothy P | LIFE | Common stock | D | 6 000 | 6 000 | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Lucas Svetlana | LIFE | Common stock | D | 6 000 | 6 000 | ||||||
| 2023-04-28 | 2023-04-26 | 4 | SCHIMMEL PAUL | LIFE | Common stock | D | 6 000 | 8 890 | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Zaknoen Sara | LIFE | Common stock | D | 6 000 | 6 000 | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Gross Jane A | LIFE | Common stock | D | 6 000 | 6 000 | ||||||
| 2023-02-06 | 2023-02-03 | 4 | Krueger Nancy | LIFE | Common stock | D | 2 688 | 7 079 | ||||||
| 2023-02-06 | 2023-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 2,3600 | −1 566 | −4 | 15 460 | ||||
| 2023-02-06 | 2023-02-03 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 3 750 | 17 026 | ||||||
| 2023-02-06 | 2023-02-03 | 4 | Shukla Sanjay | LIFE | Common stock | D | 10 375 | 61 173 | ||||||
| 2022-11-21 | 2022-11-21 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 2,1405 | 10 000 | 21 | 50 798 | ||||
| 2022-07-06 | 2022-07-01 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 2,8776 | 15 000 | 43 | 40 798 | ||||
| 2022-05-26 | 2022-05-24 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 2,81 | 88 097 | 88 097 | |||||
| 2022-05-26 | 2022-05-24 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 2,81 | 75 347 | 75 347 | |||||
| 2022-05-26 | 2022-05-24 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 2,81 | 516 280 | 516 280 | |||||
| 2022-04-28 | 2022-04-26 | 4 | CLARKE JOHN K | LIFE | Restricted Stock Units | D | 6 000 | 6 000 | ||||||
| 2022-04-28 | 2022-04-26 | 4 | SCHIMMEL PAUL | LIFE | Restricted Stock Units | D | 6 000 | 6 000 | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Coughlin Timothy P | LIFE | Restricted Stock Units | D | 6 000 | 6 000 | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Zaknoen Sara | LIFE | Restricted Stock Units | D | 6 000 | 6 000 | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Gross Jane A | LIFE | Restricted Stock Units | D | 6 000 | 6 000 | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Lucas Svetlana | LIFE | Restricted Stock Units | D | 6 000 | 6 000 | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Units | D | 15 000 | 15 000 | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 5,52 | 30 000 | 30 000 | |||||
| 2022-02-07 | 2022-02-03 | 4 | Krueger Nancy | LIFE | Restricted Stock Units | D | 10 750 | 10 750 | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 5,52 | 21 500 | 21 500 | |||||
| 2022-02-07 | 2022-02-03 | 4 | Shukla Sanjay | LIFE | Restricted Stock Units | D | 41 500 | 41 500 | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 5,52 | 83 000 | 83 000 | |||||
| 2022-01-18 | 2022-01-13 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 6,7500 | 1 923 | 13 | 12 112 | ||||
| 2022-01-10 | 2022-01-07 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 6,7613 | 5 000 | 34 | 25 798 | ||||
| 2021-11-15 | 2021-11-15 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 8,5750 | 2 500 | 21 | 20 798 | ||||
| 2021-09-22 | 2021-09-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 250 000 | 679 143 | ||||||
| 2021-09-22 | 2021-09-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | −250 000 | 2 890 | ||||||
| 2021-09-22 | 2021-09-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 8,0000 | 250 000 | 2 000 | 252 890 | ||||
| 2021-05-25 | 2021-05-21 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 4,3400 | −2 500 | −11 | 108 083 | ||||
| 2021-05-25 | 2021-05-21 | 4 | Krueger Nancy | LIFE | Employee Stock Option (Right to buy) | D | 4,45 | 59 000 | 59 000 | |||||
| 2021-05-25 | 2021-05-21 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (Right to buy) | D | 4,45 | 207 000 | 207 000 | |||||
| 2021-05-25 | 2021-05-21 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (Right to buy) | D | 4,45 | 54 000 | 54 000 | |||||
| 2021-05-25 | 2021-05-21 | 4 | Zaknoen Sara | LIFE | Stock Option (right to buy) | D | 4,45 | 2 285 | 2 285 | |||||
| 2021-05-20 | 2021-05-18 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,9800 | 50 000 | 199 | 113 023 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 4,0100 | 10 000 | 40 | 18 298 | ||||
| 2021-04-29 | 2021-04-28 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 4,21 | 1 428 | 1 428 | |||||
| 2021-04-29 | 2021-04-28 | 4 | Lucas Svetlana | LIFE | Stock Option (right to buy) | D | 4,21 | 1 428 | 1 428 | |||||
| 2021-04-29 | 2021-04-28 | 4 | Gross Jane A | LIFE | Stock Option (right to buy) | D | 4,21 | 1 428 | 1 428 | |||||
| 2021-04-29 | 2021-04-28 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 4,21 | 1 428 | 1 428 | |||||
| 2021-04-29 | 2021-04-28 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 4,21 | 1 428 | 1 428 | |||||
| 2021-03-09 | 2021-02-04 | 4/A | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,52 | 112 469 | 112 469 | |||||
| 2021-03-09 | 2020-05-26 | 4/A | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,06 | 73 142 | 73 142 | |||||
| 2021-02-09 | 2021-02-09 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 7,6600 | −390 | −3 | 9 833 | ||||
| 2021-02-09 | 2021-02-06 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Unit | D | −892 | 0 | ||||||
| 2021-02-09 | 2021-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 892 | 10 223 | ||||||
| 2021-02-09 | 2021-02-09 | 4 | Shukla Sanjay | LIFE | Common stock | D | 7,6600 | −778 | −6 | 8 298 | ||||
| 2021-02-09 | 2021-02-06 | 4 | Shukla Sanjay | LIFE | Restricted Stock Unit | D | −1 785 | 0 | ||||||
| 2021-02-09 | 2021-02-06 | 4 | Shukla Sanjay | LIFE | Common stock | D | 1 785 | 9 076 | ||||||
| 2021-02-08 | 2021-02-04 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,52 | 120 000 | 120 000 | |||||
| 2021-02-08 | 2021-02-04 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 4,52 | 45 000 | 45 000 | |||||
| 2021-02-08 | 2021-02-04 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 4,52 | 50 000 | 50 000 | |||||
| 2020-09-03 | 2020-09-02 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 4,0100 | −7 260 | −29 | 110 583 | ||||
| 2020-09-03 | 2020-08-28 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 4,0000 | −100 | −0 | 117 843 | ||||
| 2020-08-28 | 2020-08-27 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 4,0900 | −5 440 | −22 | 117 943 | ||||
| 2020-08-28 | 2020-08-26 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 4,2960 | −2 200 | −9 | 123 383 | ||||
| 2020-06-23 | 2020-06-19 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | 4,2200 | 1 850 | 8 | 9 153 | ||||
| 2020-06-23 | 2020-06-19 | 4 | Shukla Sanjay | LIFE | Common Stock | D | 4,2700 | 6 000 | 26 | 7 291 | ||||
| 2020-05-28 | 2020-05-26 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,06 | 80 000 | 0 | |||||
| 2020-05-28 | 2020-05-26 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 4,06 | 30 000 | 30 000 | |||||
| 2020-05-28 | 2020-05-26 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 4,06 | 30 000 | 30 000 | |||||
| 2020-05-28 | 2020-05-20 | 4 | Krueger Nancy | LIFE | Common Stock | D | 3,6200 | −322 | −1 | 2 735 | ||||
| 2020-05-28 | 2020-05-16 | 4 | Krueger Nancy | LIFE | Restricted Stock Unit | D | −892 | 0 | ||||||
| 2020-05-28 | 2020-05-16 | 4 | Krueger Nancy | LIFE | Common Stock | D | 892 | 3 057 | ||||||
| 2020-05-22 | 2020-05-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,6390 | −8 447 | −31 | 429 143 | ||||
| 2020-05-08 | 2020-05-06 | 4 | Lucas Svetlana | LIFE | Stock Option (right to buy) | D | 3,65 | 1 428 | 1 428 | |||||
| 2020-05-08 | 2020-05-06 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 3,65 | 1 428 | 1 428 | |||||
| 2020-05-08 | 2020-05-06 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 3,65 | 1 428 | 1 428 | |||||
| 2020-05-08 | 2020-05-06 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 3,65 | 1 428 | 1 428 | |||||
| 2020-05-08 | 2020-05-06 | 4 | Gross Jane A | LIFE | Stock Option (right to buy) | D | 3,65 | 1 428 | 1 428 | |||||
| 2020-05-08 | 2020-05-06 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | 3,65 | 1 428 | 1 428 | |||||
| 2020-02-11 | 2020-02-10 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 4,2500 | 254 000 | 1 080 | 437 590 | ||||
| 2020-02-07 | 2020-02-07 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 4,0300 | −375 | −2 | 7 125 | ||||
| 2020-02-07 | 2020-02-06 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Unit | D | −893 | 893 | ||||||
| 2020-02-07 | 2020-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | 893 | 7 500 | ||||||
| 2020-02-07 | 2020-02-05 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 4,39 | 23 359 | 23 359 | |||||
| 2020-02-07 | 2020-02-05 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 4,39 | 13 778 | 13 778 | |||||
| 2020-02-07 | 2020-02-07 | 4 | Shukla Sanjay | LIFE | Common stock | D | 4,0300 | −745 | −3 | 1 291 | ||||
| 2020-02-07 | 2020-02-06 | 4 | Shukla Sanjay | LIFE | Restricted Stock Unit | D | −1 786 | 1 786 | ||||||
| 2020-02-07 | 2020-02-06 | 4 | Shukla Sanjay | LIFE | Common stock | D | 1 786 | 2 036 | ||||||
| 2020-02-07 | 2020-02-05 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,39 | 39 327 | 39 327 | |||||
| 2019-07-02 | 2019-06-28 | 4 | Gross Jane A | LIFE | Stock Option (right to buy) | D | 5,13 | 2 285 | 2 285 | |||||
| 2019-07-02 | 2019-06-28 | 4 | Lucas Svetlana | LIFE | Stock Option (right to buy) | D | 5,13 | 2 285 | 2 285 | |||||
| 2019-05-20 | 2019-05-17 | 4 | Krueger Nancy | LIFE | Common Stock | D | 0,4501 | −4 651 | −2 | 25 348 | ||||
| 2019-05-20 | 2019-05-16 | 4 | Krueger Nancy | LIFE | Restricted Stock Units | D | 0,00 | −12 500 | 12 500 | |||||
| 2019-05-20 | 2019-05-16 | 4 | Krueger Nancy | LIFE | Common Stock | D | 12 500 | 29 999 | ||||||
| 2019-05-10 | 2019-05-08 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 0,58 | 20 000 | 20 000 | |||||
| 2019-05-10 | 2019-05-08 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 0,58 | 20 000 | 20 000 | |||||
| 2019-05-10 | 2019-05-08 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 0,58 | 20 000 | 20 000 | |||||
| 2019-05-10 | 2019-05-08 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | 0,58 | 20 000 | 20 000 | |||||
| 2019-05-10 | 2019-05-08 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | 0,58 | 20 000 | 20 000 | |||||
| 2019-05-10 | 2019-05-08 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 0,58 | 20 000 | 20 000 | |||||
| 2019-04-16 | 2019-04-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,5410 | 1 848 428 | 1 000 | 2 570 242 | ||||
| 2019-02-08 | 3 | Krueger Nancy | LIFE | Common Stock | D | 29 998 | ||||||||
| 2019-02-08 | 3 | Krueger Nancy | LIFE | Common Stock | D | 29 998 | ||||||||
| 2019-02-08 | 3 | Krueger Nancy | LIFE | Common Stock | D | 29 998 | ||||||||
| 2019-02-08 | 2019-02-06 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 0,52 | 125 000 | 125 000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Unit | D | 25 000 | 25 000 | ||||||
| 2019-02-08 | 2019-02-06 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 0,52 | 50 000 | 50 000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Shukla Sanjay | LIFE | Restricted Stock Unit | D | 50 000 | 50 000 | ||||||
| 2019-02-08 | 2019-02-06 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 0,52 | 200 000 | 200 000 | |||||
| 2018-12-26 | 2018-12-21 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 0,4236 | 195 000 | 83 | 615 382 | ||||
| 2018-12-26 | 2018-12-20 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 0,4129 | 50 000 | 21 | 420 382 | ||||
| 2018-11-28 | 2018-11-26 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,5420 | 147 225 | 80 | 882 302 | ||||
| 2018-09-21 | 2018-09-20 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | 0,8352 | 38 000 | 32 | 90 000 | ||||
| 2018-09-21 | 2018-09-19 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | 0,8122 | 26 000 | 21 | 52 000 | ||||
| 2018-09-18 | 2018-09-14 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | 0,7329 | 26 000 | 19 | 26 000 | ||||
| 2018-09-05 | 2018-09-04 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,7571 | 20 749 | 16 | 735 077 | ||||
| 2018-09-05 | 2018-08-31 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,7160 | 22 000 | 16 | 714 328 | ||||
| 2018-08-31 | 2018-08-30 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,7559 | 89 275 | 67 | 692 328 | ||||
| 2018-08-31 | 2018-08-29 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,7199 | 75 136 | 54 | 603 053 | ||||
| 2018-08-01 | 2018-07-30 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | 0,82 | 200 000 | 200 000 | |||||
| 2018-06-07 | 2018-05-31 | 4 | Amanullah Ashraf | LIFE | Restricted Stock Units | D | 0,00 | 3 333 | 3 333 | |||||
| 2018-06-07 | 2018-05-31 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | 3 333 | 26 264 | ||||||
| 2018-05-21 | 2018-05-18 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 0,9963 | 150 000 | 149 | 527 917 | ||||
| 2018-05-17 | 2018-05-15 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 1,35 | 20 000 | 20 000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 1,35 | 20 000 | 20 000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 1,35 | 20 000 | 20 000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | 1,35 | 20 000 | 20 000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | 1,35 | 20 000 | 20 000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | 1,35 | 20 000 | 20 000 | |||||
| 2018-05-17 | 2018-05-15 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 1,35 | 20 000 | 20 000 | |||||
| 2018-05-16 | 2018-05-16 | 4 | EcoR1 Capital Fund Qualified, L.P. | LIFE | Common Stock | D | 0,8111 | −2 733 231 | −2 217 | 0 | ||||
| 2018-05-16 | 2018-05-15 | 4 | EcoR1 Capital Fund Qualified, L.P. | LIFE | Common Stock | D | 1,4268 | −121 294 | −173 | 2 733 231 | ||||
| 2018-05-16 | 2018-05-14 | 4 | EcoR1 Capital Fund Qualified, L.P. | LIFE | Common Stock | D | 1,7167 | −354 791 | −609 | 2 854 525 | ||||
| 2018-05-02 | 3 | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 2001 | LIFE | Common Stock | I | 23 908 | ||||||||
| 2018-05-02 | 3 | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 2001 | LIFE | Common Stock | I | 23 908 | ||||||||
| 2018-05-02 | 3 | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 2001 | LIFE | Common Stock | I | 23 908 | ||||||||
| 2018-02-08 | 2018-02-06 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 300 000 | 300 000 | |||||
| 2018-02-08 | 2018-02-08 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | 3,4000 | −1 402 | −5 | 1 932 | ||||
| 2018-02-08 | 2018-02-07 | 4 | Amanullah Ashraf | LIFE | Restricted Stock Units | D | 0,00 | −3 334 | 6 666 | |||||
| 2018-02-08 | 2018-02-07 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | 3 334 | 3 334 | ||||||
| 2018-02-08 | 2018-02-06 | 4 | Amanullah Ashraf | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 100 000 | 100 000 | |||||
| 2018-02-08 | 2018-02-08 | 4 | Blake John T | LIFE | Common Stock | D | 3,4000 | −1 402 | −5 | 1 932 | ||||
| 2018-02-08 | 2018-02-07 | 4 | Blake John T | LIFE | Restricted Stock Units | D | 0,00 | −3 334 | 6 666 | |||||
| 2018-02-08 | 2018-02-07 | 4 | Blake John T | LIFE | Common Stock | D | 3 334 | 3 334 | ||||||
| 2018-02-08 | 2018-02-06 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 75 000 | 75 000 | |||||
| 2018-02-08 | 2018-02-06 | 4 | King David John | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 150 000 | 150 000 | |||||
| 2018-01-02 | 2018-01-02 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | 3,80 | 32 000 | 32 000 | |||||
| 2017-12-14 | 2017-11-13 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 3,9500 | −1 083 | −4 | 3 209 316 | ||||
| 2017-12-14 | 2017-11-10 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 4,0008 | −5 860 | −23 | 3 210 399 | ||||
| 2017-12-14 | 2017-11-09 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 4,1504 | −5 819 | −24 | 3 216 259 | ||||
| 2017-12-14 | 2017-11-08 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 4,3000 | −1 070 | −5 | 3 222 078 | ||||
| 2017-12-14 | 2017-11-01 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 4,8000 | 24 728 | 119 | 3 223 148 | ||||
| 2017-12-14 | 2017-10-01 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 5,0500 | 4 879 | 25 | 3 198 420 | ||||
| 2017-11-03 | 2017-11-01 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,00 | 450 000 | 450 000 | |||||
| 2017-09-07 | 3 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 6 387 082 | ||||||||
| 2017-09-07 | 3 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | 6 387 082 | ||||||||
| 2017-09-05 | 2017-08-31 | 4 | SCHIMMEL PAUL | LIFE | Warrant to Purchase Common Stock | I | 4,64 | 35 376 | 35 376 | |||||
| 2017-09-05 | 2017-08-31 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,6500 | 94 336 | 250 | 377 917 | ||||
| 2017-09-05 | 2017-08-31 | 4 | MENDLEIN JOHN | LIFE | Warrant to Purchase Common Stock | D | 4,64 | 14 151 | 14 151 | |||||
| 2017-09-05 | 2017-08-31 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 2,6500 | 37 736 | 100 | 367 883 | ||||
| 2017-05-11 | 3/A | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 9, 2001 | LIFE | Common Stock | I | 11 805 | ||||||||
| 2017-05-11 | 2017-05-09 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | 3,15 | 20 000 | 20 000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 3,15 | 20 000 | 20 000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | 3,15 | 20 000 | 20 000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | 3,15 | 20 000 | 20 000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 3,15 | 20 000 | 20 000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 3,15 | 20 000 | 20 000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | 3,15 | 20 000 | 20 000 | |||||
| 2017-05-11 | 2017-05-09 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 3,15 | 20 000 | 20 000 | |||||
| 2017-04-26 | 2017-04-24 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 3,0000 | 124 | 0 | 327 647 | ||||
| 2017-04-20 | 2017-04-20 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 3,0000 | 1 552 | 5 | 327 523 | ||||
| 2017-04-20 | 2017-04-18 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 3,0000 | 1 000 | 3 | 325 971 | ||||
| 2017-04-10 | 2017-04-07 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | 3,25 | 32 000 | 32 000 | |||||
| 2017-04-04 | 2017-04-03 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | 3,50 | 32 000 | 32 000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 65 000 | 65 000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 40 000 | 40 000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | Matsuoka Grove | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 20 000 | 20 000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 185 000 | 185 000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | Blake John T | LIFE | Restricted Stock Unit | D | 10 000 | 10 000 | ||||||
| 2017-02-09 | 2017-02-07 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 55 000 | 55 000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | King David John | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 65 000 | 65 000 | |||||
| 2017-02-09 | 2017-02-07 | 4 | Amanullah Ashraf | LIFE | Restricted Stock Unit | D | 10 000 | 10 000 | ||||||
| 2017-02-09 | 2017-02-07 | 4 | Amanullah Ashraf | LIFE | Employee Stock Option (right to buy) | D | 3,30 | 35 000 | 35 000 | |||||
| 2016-12-22 | 2016-12-21 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,2818 | 10 000 | 23 | 721 814 | ||||
| 2016-12-22 | 2016-12-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,2740 | 15 000 | 34 | 711 814 | ||||
| 2016-12-21 | 2016-12-19 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 2,1980 | 69 000 | 152 | 324 971 | ||||
| 2016-12-21 | 2016-12-20 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | 2,2499 | 11 000 | 25 | 11 000 | ||||
| 2016-12-19 | 2016-12-16 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,3973 | 10 000 | 24 | 696 814 | ||||
| 2016-12-19 | 2016-12-15 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 2,4978 | 40 000 | 100 | 686 814 | ||||
| 2016-12-19 | 2016-09-23 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 12 572 | 646 814 | ||||||
| 2016-12-19 | 2016-09-23 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | −12 572 | 40 440 | ||||||
| 2016-09-22 | 2016-09-21 | 4 | King David John | LIFE | Employee Stock Option (right to buy) | D | 3,29 | 145 000 | 145 000 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 25 000 | 25 000 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 19 000 | 19 000 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 45 500 | 45 500 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Amanullah Ashraf | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 28 000 | 28 000 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 27 500 | 27 500 | |||||
| 2016-09-15 | 2016-09-13 | 4 | Matsuoka Grove | LIFE | Employee Stock Option (right to buy) | D | 3,06 | 20 000 | 20 000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 3,33 | 18 000 | 18 000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | 3,33 | 18 000 | 18 000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 3,33 | 18 000 | 18 000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | FALBERG KATHRYN E | LIFE | Stock Option (right to buy) | D | 3,33 | 18 000 | 18 000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 3,33 | 18 000 | 18 000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | 3,33 | 18 000 | 18 000 | |||||
| 2016-05-26 | 2016-05-24 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | 3,33 | 18 000 | 18 000 | |||||
| 2016-05-11 | 2016-05-11 | 4 | Matsuoka Grove | LIFE | Common Stock | D | 3,0300 | 10 000 | 30 | 12 412 | ||||
| 2016-05-11 | 2016-05-09 | 4 | Matsuoka Grove | LIFE | Common Stock | D | 3,0800 | 2 412 | 7 | 2 412 | ||||
| 2016-05-03 | 2016-05-03 | 4 | Matsuoka Grove | LIFE | Stock Option (right to buy) | D | 3,67 | 145 000 | 145 000 | |||||
| 2016-04-15 | 2016-04-14 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 4,1434 | 32 600 | 135 | 53 012 | ||||
| 2016-04-15 | 2016-04-14 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 4,2196 | 33 619 | 142 | 283 581 | ||||
| 2016-04-14 | 2016-04-13 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,8500 | 9 835 | 38 | 249 962 | ||||
| 2016-04-13 | 2016-04-11 | 4/A | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,5913 | 22 100 | 79 | 233 581 | ||||
| 2016-04-13 | 2016-04-11 | 4/A | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,4481 | 5 300 | 18 | 211 481 | ||||
| 2016-04-13 | 2016-04-11 | 4/A | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,5921 | 5 259 | 19 | 17 831 | ||||
| 2016-04-13 | 2016-04-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 3,6999 | 6 546 | 24 | 240 127 | ||||
| 2016-04-13 | 2016-04-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,7512 | 2 581 | 10 | 20 412 | ||||
| 2016-04-12 | 2016-04-11 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,4481 | 5 300 | 18 | 220 231 | ||||
| 2016-04-12 | 2016-04-11 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,5915 | 27 359 | 98 | 214 931 | ||||
| 2016-04-11 | 2016-04-08 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,2194 | 85 000 | 274 | 187 572 | ||||
| 2016-04-08 | 2016-04-07 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,1896 | 40 000 | 128 | 102 572 | ||||
| 2016-04-07 | 2016-04-05 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 3,5200 | 2 500 | 9 | 250 971 | ||||
| 2016-04-07 | 2016-04-06 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,2000 | 25 000 | 80 | 62 572 | ||||
| 2016-04-06 | 2016-04-05 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | 3,5247 | 25 000 | 88 | 37 572 | ||||
| 2016-04-06 | 2016-04-05 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 3,5500 | 2 500 | 9 | 248 471 | ||||
| 2016-04-01 | 3 | Shukla Sanjay | LIFE | Common Stock | D | 7 000 | ||||||||
| 2016-04-01 | 3 | Shukla Sanjay | LIFE | Common Stock | D | 7 000 | ||||||||
| 2016-04-01 | 2016-03-30 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | 4,86 | 163 000 | 163 000 | |||||
| 2016-03-30 | 2016-03-28 | 4 | Blackburn Kelly | LIFE | Restricted Stock Unit | D | 21 600 | 21 600 | ||||||
| 2016-03-30 | 2016-03-28 | 4 | Cubitt Andrew | LIFE | Restricted Stock Unit | D | 13 000 | 13 000 | ||||||
| 2016-01-29 | 2016-01-27 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | 6,14 | 19 428 | 19 428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | 6,14 | 19 428 | 19 428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 20 000 | 20 000 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 8 500 | 8 500 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 18 250 | 18 250 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 20 000 | 20 000 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Blackburn Stan | LIFE | Stock Option (right to buy) | D | 6,14 | 4 250 | 4 250 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 18 250 | 18 250 | |||||
| 2016-01-29 | 2016-01-27 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 8 500 | 8 500 | |||||
| 2016-01-29 | 2016-01-27 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | 6,14 | 19 428 | 19 428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 6,14 | 19 428 | 19 428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | FALBERG KATHRYN E | LIFE | Stock Option (right to buy) | D | 6,14 | 19 428 | 19 428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 6,14 | 19 428 | 19 428 | |||||
| 2016-01-29 | 2016-01-27 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 135 000 | 135 000 | |||||
| 2016-01-29 | 2016-01-27 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 6,14 | 19 428 | 19 428 | |||||
| 2016-01-29 | 2015-09-16 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | −11 925 | 634 242 | ||||||
| 2016-01-29 | 2016-01-27 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | 6,14 | 40 000 | 40 000 | |||||
| 2016-01-06 | 2016-01-04 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 148 732 | 148 732 | |||||
| 2016-01-06 | 2016-01-04 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 25 913 | 25 913 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 10 831 | 10 831 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Graham Marcy | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 12 023 | 12 023 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 16 874 | 16 874 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 14 829 | 14 829 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 5 038 | 5 038 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Blackburn Stan | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 5 754 | 5 754 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 26 470 | 26 470 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 29 659 | 29 659 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 10 750 | 10 750 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | 9,13 | 153 000 | 153 000 | |||||
| 2015-10-30 | 2015-10-28 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | 12,49 | 7 500 | 7 500 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ramsdell Fred | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 5 393 | 5 393 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ramsdell Fred | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 12 000 | 12 000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 65 070 | 65 070 | |||||
| 2015-10-05 | 2015-10-01 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 71 000 | 71 000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 11 337 | 11 337 | |||||
| 2015-10-05 | 2015-10-01 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 23 000 | 23 000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 4 739 | 4 739 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 17 000 | 17 000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Graham Marcy | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 5 260 | 5 260 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Graham Marcy | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 28 000 | 28 000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 7 382 | 7 382 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 23 000 | 23 000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 6 488 | 6 488 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 24 000 | 24 000 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Stan | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 2 518 | 2 518 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Stan | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 9 500 | 9 500 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 11 581 | 11 581 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 45 500 | 45 500 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 12 976 | 12 976 | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | 10,24 | 30 000 | 30 000 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | 14,96 | 6 286 | 6 286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | 14,96 | 6 286 | 6 286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | 14,96 | 6 286 | 6 286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | 14,96 | 6 286 | 6 286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | 14,96 | 6 286 | 6 286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | 14,96 | 6 286 | 6 286 | |||||
| 2015-07-10 | 2015-07-08 | 4 | FALBERG KATHRYN E | LIFE | Stock Option (right to buy) | D | 14,96 | 6 286 | 6 286 | |||||
| 2015-05-14 | 3/A | SCHIMMEL PAUL | LIFE | Common Stock | D | 12 572 | ||||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series E Redeemable Convertible Preferred Stock | I | −446 827 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series D Redeemable Convertible Preferred Stock | I | −15 031 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series C Redeemable Convertible Preferred Stock | I | −558 508 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | −1 440 058 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series B Redeemable Convertible Preferred Stock | I | −1 200 000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series A Redeemable Convertible Preferred Stock | I | −525 000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series D Redeemable Convertible Preferred Stock | I | −248 024 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 46 152 | 646 167 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 470 020 | 600 015 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | 31 181 | 31 181 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | AKKARAJU SRINIVAS By Sofinnova Venture Partners IX, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | −14 968 722 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | AKKARAJU SRINIVAS By Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | I | 14,0000 | 320 000 | 4 480 | 1 866 126 | ||||
| 2015-05-14 | 2015-05-12 | 4 | AKKARAJU SRINIVAS By Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | I | 1 546 126 | 1 546 126 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | MENDLEIN JOHN | LIFE | Series D Redeemable Convertible Preferred Stock | D | −21 122 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | MENDLEIN JOHN | LIFE | Series C Redeemable Convertible Preferred Stock | D | −170 218 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | 24 055 | 245 971 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series D Redeemable Convertible Preferred Stock | I | −1 536 787 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series C Redeemable Convertible Preferred Stock | I | −2 127 660 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | −4 320 173 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series B Redeemable Convertible Preferred Stock | I | −3 600 000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series A Redeemable Convertible Preferred Stock | I | −2 400 000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series E Redeemable Convertible Preferred Stock | D | −893 655 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | 1 758 158 | 1 758 158 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Common Stock | D | 92 306 | 104 878 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | D | −893 655 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | D | −1 126 866 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | D | −4 361 703 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | D | −4 320 173 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | D | −3 600 000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Common Stock | D | 92 306 | 1 778 064 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Common Stock | D | 1 685 758 | 1 685 758 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series D Redeemable Convertible Preferred Stock | D | −1 536 787 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series C Redeemable Convertible Preferred Stock | D | −2 127 660 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series B-2 Redeemable Convertible Preferred Stock | D | −4 320 173 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series B Redeemable Convertible Preferred Stock | D | −3 600 000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series A Redeemable Convertible Preferred Stock | D | −2 400 000 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Common Stock | D | 1 758 158 | 1 758 158 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | −8 623 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | −5 906 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | −16 806 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | −862 318 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | −14 706 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | −10 074 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | −28 661 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | −1 470 577 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | −42 087 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | −28 831 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | −82 029 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | −4 208 756 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | −41 686 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | −28 556 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | −81 248 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | −4 168 683 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | −34 737 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | −23 796 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | −67 704 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | −3 473 763 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | 890 | 17 638 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | 610 | 12 082 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | 1 736 | 34 378 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | 89 069 | 1 763 894 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | 16 748 | 16 748 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | 11 472 | 11 472 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | 32 642 | 32 642 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | 1 674 825 | 1 674 825 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | −8 623 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | −5 906 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | −16 806 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | −862 318 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | −14 706 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | −10 074 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | −28 661 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | −1 470 577 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | −42 087 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | −28 831 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | −82 029 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | −4 208 756 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | −41 686 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | −28 556 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | −81 248 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | −4 168 683 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | −34 737 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | −23 796 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | −67 704 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | −3 473 763 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | 890 | 17 638 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | 610 | 12 082 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | 1 736 | 34 378 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | 89 069 | 1 763 894 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | 16 748 | 16 748 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | 11 472 | 11 472 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | 32 642 | 32 642 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | 1 674 825 | 1 674 825 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Sofinnova Venture Partners IX, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | D | −14 968 722 | 0 | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | D | 14,0000 | 320 000 | 4 480 | 1 866 126 | ||||
| 2015-05-14 | 2015-05-12 | 4 | Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | D | 1 546 126 | 1 546 126 | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | LIFE | Series E Preferred Stock | I | −2 234 137 | 0 | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | LIFE | Series E Preferred Stock | I | −2 234 137 | 0 | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | LIFE | Common Stock | I | 14,0000 | 25 000 | 350 | 255 764 | ||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | LIFE | Common Stock | I | 14,0000 | 25 000 | 350 | 255 764 | ||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | LIFE | Common Stock | I | 230 764 | 230 764 | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | LIFE | Common Stock | I | 230 764 | 230 764 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Series E Preferred Stock | D | −6 581 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Series D Preferred Stock | D | −11 182 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Series C Preferred Stock | D | −90 110 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Common Stock | D | 13 414 | 13 414 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Series E Preferred Stock | D | −887 073 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Series D Preferred Stock | D | −1 506 901 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Series C Preferred Stock | D | −12 143 933 | 0 | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Common Stock | D | 1 807 820 | 1 807 820 | ||||||
| 2015-05-08 | 2015-05-06 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | 14,00 | 163 437 | 163 437 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Ramsdell Fred | LIFE | Stock Option (right to buy) | D | 14,00 | 17 600 | 17 600 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Chrzanowski Holly D. | LIFE | Stock Option (right to buy) | D | 14,00 | 11 943 | 11 943 | |||||
| 2015-05-08 | 2015-05-06 | 4 | McKew John C. | LIFE | Stock Option (right to buy) | D | 14,00 | 25 144 | 25 144 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Blackburn Kelly | LIFE | Stock Option (right to buy) | D | 14,00 | 34 573 | 34 573 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Blackburn Stan | LIFE | Stock Option (right to buy) | D | 14,00 | 4 085 | 4 085 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Chereau Frederic | LIFE | Stock Option (right to buy) | D | 14,00 | 22 001 | 22 001 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Graham Marcy | LIFE | Stock Option (right to buy) | D | 14,00 | 10 686 | 10 686 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Krueger Nancy | LIFE | Stock Option (right to buy) | D | 14,00 | 8 800 | 8 800 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Ashlock Melissa A. | LIFE | Stock Option (right to buy) | D | 14,00 | 25 144 | 25 144 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Weiner David M. | LIFE | Stock Option (right to buy) | D | 14,00 | 44 002 | 44 002 | |||||
| 2015-05-08 | 2015-05-06 | 4 | Cubitt Andrew | LIFE | Stock Option (right to buy) | D | 14,00 | 5 657 | 5 657 | |||||
| 2015-05-06 | 3 | FALBERG KATHRYN E | LIFE | Common Stock | D | 25 144 | ||||||||
| 2015-05-06 | 3 | FALBERG KATHRYN E | LIFE | Common Stock | D | 25 144 | ||||||||
| 2015-05-06 | 3 | Nashat Amir | LIFE | Common Stock | D | 25 144 | ||||||||
| 2015-05-06 | 3 | Nashat Amir | LIFE | Common Stock | D | 25 144 | ||||||||
| 2015-05-06 | 3 | Ashlock Melissa A. | LIFE | Common Stock | D | 136 328 | ||||||||
| 2015-05-06 | 3 | Ashlock Melissa A. | LIFE | Common Stock | D | 136 328 | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL By Schimmel Revocable Trust U/A Dtd 9/6/2000 | LIFE | Common Stock | I | 269 419 | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL | LIFE | Common Stock | D | 148 853 | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL | LIFE | Common Stock | D | 148 853 | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL By Schimmel Revocable Trust U/A Dtd 9/6/2000 | LIFE | Common Stock | I | 269 419 | ||||||||
| 2015-05-06 | 3 | CLARKE JOHN K | LIFE | Common Stock | D | 25 144 | ||||||||
| 2015-05-06 | 3 | CLARKE JOHN K | LIFE | Common Stock | D | 25 144 | ||||||||
| 2015-05-06 | 3 | MENDLEIN JOHN | LIFE | Common Stock | D | 443 832 | ||||||||
| 2015-05-06 | 3 | MENDLEIN JOHN | LIFE | Common Stock | D | 443 832 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | 18 858 | ||||||||
| 2015-05-06 | 3 | Chrzanowski Holly D. | LIFE | Common Stock | D | 3 770 | ||||||||
| 2015-05-06 | 3 | Chrzanowski Holly D. | LIFE | Common Stock | D | 3 770 | ||||||||
| 2015-05-06 | 3 | Blackburn Kelly | LIFE | Common Stock | D | 558 | ||||||||
| 2015-05-06 | 3 | Blackburn Kelly | LIFE | Common Stock | D | 558 | ||||||||
| 2015-05-06 | 3 | Chereau Frederic | LIFE | Common Stock | D | 25 734 | ||||||||
| 2015-05-06 | 3 | Chereau Frederic | LIFE | Common Stock | D | 25 734 | ||||||||
| 2015-05-06 | 3 | Blackburn Stan By the J. Stanhope Blackburn and Karlene S. Blackburn Family Trust U.T.D. May 9, 2001 | LIFE | Common Stock | I | 189 951 | ||||||||
| 2015-05-06 | 3 | Blackburn Stan | LIFE | Common Stock | D | 98 199 | ||||||||
| 2015-05-06 | 3 | Blackburn Stan By the J. Stanhope Blackburn and Karlene S. Blackburn Family Trust U.T.D. May 9, 2001 | LIFE | Common Stock | I | 189 951 | ||||||||
| 2015-05-06 | 3 | Blackburn Stan | LIFE | Common Stock | D | 98 199 | ||||||||
| 2015-05-06 | 3 | Weiner David M. | LIFE | Common Stock | D | 10 056 | ||||||||
| 2015-05-06 | 3 | Weiner David M. | LIFE | Common Stock | D | 10 056 |
P
Köp på öppna marknaden eller privat köp av icke-derivatsäkerhet
S
Köp på öppna marknaden eller privat försäljning av icke-derivatsäkerhet
A
Bevilja, tilldelning eller annat förvärv av värdepapper från företaget (såsom en option)
C
Omvandling av derivat
D
Försäljning eller överföring av värdepapper tillbaka til företaget
F
Betalning av lösenpris eller skatteskuld med del av värdepapper som erhållits från bolaget
G
Överlåtelse av värdepapper från eller till insidern
K
Aktieswappar och liknande säkringsaffärer
M
Utövande eller omvandling av derivatsäkerhet som erhållits från företaget (som en option)
V
En transaktion friviligt rapporterad på schema 4
J
Andra (med en fotnot som beskriver transaktionen)
