JHG / Janus Henderson Group plc - SEC-arkiveringar, Årsredovisning, Fullmaktsutlåtande

Janus Henderson Group plc
US ˙ NYSE ˙ JE00BYPZJM29

Grundläggande statistik
LEI 2138009WPYMWJN3RVF44
CIK 1274173
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Janus Henderson Group plc
SEC Filings (Chronological Order)
Denna sida innehåller en komplett, kronologisk lista över SEC-arkiveringar, exklusive ägande-arkiveringar som vi tillhandahåller på andra ställen.
June 2, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 29, 2026 JANUS HENDERSON GROU

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 29, 2026 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 001-38103 98-1376360 (State or other jurisdiction of (Commission

May 8, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2026 Commission File Numbe

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2026 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands (State or other jurisdiction of i

May 8, 2026 EX-99.1

Janus Henderson Group plc Reports First Quarter 2026 Results

Exhibit 99.1 Janus Henderson Group plc Reports First Quarter 2026 Results ● Solid long-term investment performance, with 66%, 67%, and 68% of assets under management (“AUM”) outperforming relevant benchmarks on a three-, five-, and 10-year basis, respectively, as of March 31, 2026 ● AUM of US$480 billion as of March 31, 2026, an increase of 29% year over year ● First quarter 2026 net inflows of US

May 8, 2026 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2026 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the transition period from to Commission File Number 001-38103 JAN

April 30, 2026 CT ORDER

CT ORDER

UNITED STATES SECURITIES AND EXCHANGE COMMISSION April 29, 2026 ORDER GRANTING CONFIDENTIAL TREATMENT UNDER THE SECURITIES EXCHANGE ACT OF 1934 Janus Henderson Group plc File No.

April 30, 2026 CT ORDER

CT ORDER

UNITED STATES SECURITIES AND EXCHANGE COMMISSION April 29, 2026 ORDER GRANTING CONFIDENTIAL TREATMENT UNDER THE SECURITIES EXCHANGE ACT OF 1934 Janus Henderson Group plc File No.

April 30, 2026 CT ORDER

CT ORDER

UNITED STATES SECURITIES AND EXCHANGE COMMISSION April 29, 2026 ORDER GRANTING CONFIDENTIAL TREATMENT UNDER THE SECURITIES EXCHANGE ACT OF 1934 Janus Henderson Group plc File No.

April 30, 2026 CT ORDER

CT ORDER

UNITED STATES SECURITIES AND EXCHANGE COMMISSION April 29, 2026 ORDER GRANTING CONFIDENTIAL TREATMENT UNDER THE SECURITIES EXCHANGE ACT OF 1934 Janus Henderson Group plc File No.

April 17, 2026 ARS

FORM ARS

INVESTING IN A BRIGHTER FUTURE TOGETHER 2025 ANNUAL REPORTAssets under management (AUM) $ 493.

April 17, 2026 DEF 14A

MESSAGE FROM OUR BOARD CHAIR NOTICE OF 2026 ANNUAL GENERAL MEETING OF SHAREHOLDERS TABLE OF CONTENTS PROXY SUMMARY PROPOSAL 1 ELECTION OF DIRECTORS CORPORATE GOVERNANCE BOARD COMPENSATION PROPOSAL 2 APPROVAL TO INCREASE THE CAP ON AGGREGATE ANNUAL CO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

April 17, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 16, 2026 Commission File Nu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 16, 2026 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 98-1376360 (State or other jur

April 17, 2026 DEF 14A

DEFINITIVE PROXY STATEMENT

INVESTING IN A BRIGHTER FUTURE TOGETHER 2026 NOTICE OF ANNUAL GENERAL MEETING OF SHAREHOLDERS AND PROXY STATEMENT MAY 29, 2026ABOUT JANUS HENDERSON GROUP PLC Janus Henderson is an independent global asset manager offering a broad range of investment solutions across all major asset classes to a client base around the world.

April 17, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )

JANUS HENDERSON GROUP PLC - DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

April 13, 2026 SC 13E3/A

As filed with the Securities and Exchange Commission on April 13, 2026 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13E-3 RULE 13E-3 TRANSACTION STATEMENT UNDER SECTION 13(E) OF THE SECURITIES ACT OF 1934 (Amendment No. 4) Janus

As filed with the Securities and Exchange Commission on April 13, 2026 SECURITIES AND EXCHANGE COMMISSION Washington, D.

April 13, 2026 EX-99.(C)(I)

Highly Confidential & Proprietary December 1, 2025 Project Jewel Discussion Materials Goldman Sachs & Co. DRAFT Preliminary – Subject to Refinement 2 DRAFT Preliminary – Subject to Refinement Disclaimer These materials have been prepared by Goldman S

Exhibit 99.(c)(i) Highly Confidential & Proprietary December 1, 2025 Project Jewel Discussion Materials Goldman Sachs & Co. DRAFT Preliminary – Subject to Refinement 2 DRAFT Preliminary – Subject to Refinement Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in

April 13, 2026 EX-99.(C)(II)

Highly Confidential & Proprietary December 2, 2025 Project Jewel Discussion Materials Goldman Sachs & Co. DRAFT Preliminary – Subject to Refinement 2 DRAFT Preliminary – Subject to Refinement Disclaimer These materials have been prepared by Goldman S

Exhibit 99.(c)(ii) Highly Confidential & Proprietary December 2, 2025 Project Jewel Discussion Materials Goldman Sachs & Co. DRAFT Preliminary – Subject to Refinement 2 DRAFT Preliminary – Subject to Refinement Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in

April 9, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

April 9, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

April 7, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

April 3, 2026 PRE 14A

MESSAGE FROM OUR BOARD CHAIR NOTICE OF 2026 ANNUAL GENERAL MEETING OF SHAREHOLDERS TABLE OF CONTENTS PROXY SUMMARY PROPOSAL 1 ELECTION OF DIRECTORS CORPORATE GOVERNANCE BOARD COMPENSATION PROPOSAL 2 APPROVAL TO INCREASE THE CAP ON AGGREGATE ANNUAL CO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

March 31, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 30, 2026 EX-FILING FEES

Table 1: Transaction Valuation

Calculation of Filing Fee Tables Table 1: Transaction Valuation Transaction Valuation Fee Rate Amount of Filing Fee Fees to be Paid 1 $ 470,521,344.

March 30, 2026 SC 13E3/A

As filed with the Securities and Exchange Commission on March 27, 2026 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13E-3 RULE 13E-3 TRANSACTION STATEMENT UNDER SECTION 13(E) OF THE SECURITIES ACT OF 1934 (Amendment No. 3) Janus

As filed with the Securities and Exchange Commission on March 27, 2026 SECURITIES AND EXCHANGE COMMISSION Washington, D.

March 30, 2026 EX-99.(B)(IV)

Jupiter Company Limited Jupiter Borrower, Inc. c/o Trian Fund Management, L.P. 280 Park Avenue, 41st Floor New York, NY 10017

Exhibit 99.(b)(iv) Execution Version Jupiter Company Limited Jupiter Borrower, Inc. c/o Trian Fund Management, L.P. 280 Park Avenue, 41st Floor New York, NY 10017 March 24, 2026 JPMORGAN CHASE BANK, N.A. 270 Park Avenue New York, New York 10017 CITIGROUP GLOBAL MARKETS INC. 388 Greenwich Street New York, New York 10013 BANK OF AMERICA, N.A. BOFA SECURITIES, INC One Bryant Park New York, New York 1

March 30, 2026 EX-99.(C)(XI)

2 114:151:197 255:255:255 0:0:0 Brand Colors A. 240:235:230 167:162:157 114:115:117 Brand Grays B. 220:220:224 187:187:191 Background Grays C. 253:243:173 184:208:245 242:203:231 153:224:217 245:208:206 198:233:189 Table Highlight D. E. 0:0:0 114:115

Exhibit 99.(c)(xi) 114:151:197 255:255:255 0:0:0 Brand Colors A. 240:235:230 167:162:157 114:115:117 Brand Grays B. 220:220:224 187:187:191 Background Grays C. 253:243:173 184:208:245 242:203:231 153:224:217 245:208:206 198:233:189 Table Highlight D. E. 0:0:0 114:115:117 Table Borders F. Functional Data Colors G. 194:23:10 243:196:63 57:128:37 Primary Sequence 9:44:97 114:151:197 166:66:140 21:151

March 30, 2026 EX-99.(D)(XI)

[Signature Pages Follow]

Exhibit 99.(d)(xi) EXECUTION VERSION March 24, 2026 Jupiter Company Limited c/o Trian Fund Management, L.P. 280 Park Avenue 41st Floor New York, NY 10017 Re: Amended and Restated Equity Financing Commitment Ladies and Gentlemen: Reference is made to the Agreement and Plan of Merger, dated as of December 21, 2025, as amended by Amendment No. 1 thereto dated as of the date hereof (as amended, supple

March 30, 2026 EX-99.(C)(XII)

2 Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in connection with an informational presentation which Goldma

Exhibit 99.(c)(xii) March 23, 2026 Project Jewel Discussion Materials Goldman Sachs & Co. 2 Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in connection with an informational presentation which Goldman Sachs is making to the Special Committee. These materials

March 30, 2026 EX-99.(D)(XII)

AMENDED AND RESTATED LIMITED GUARANTEE

Exhibit 99.(d)(xii) EXECUTION VERSION AMENDED AND RESTATED LIMITED GUARANTEE This AMENDED AND RESTATED LIMITED GUARANTEE, dated as of March 24, 2026 (this “Limited Guarantee”), by each Person listed on Schedule A hereto (each a “Guarantor” and, collectively, the “Guarantors”), in favor of Janus Henderson Group plc, a public limited company organized under the Laws of Jersey (the “Guaranteed Party”

March 27, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 27, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 25, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 24, 2026 Commission File Nu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 24, 2026 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 98-1376360 (State or other jur

March 25, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 25, 2026 EX-99.1

March 2026 DELIVERING MAXIMUM VALUE AND CERTAINTY FOR SHAREHOLDERS

Exhibit 99.1 March 2026 DELIVERING MAXIMUM VALUE AND CERTAINTY FOR SHAREHOLDERS 2 DISCLAIMERS Forward Looking Statements Certain statements in this investor presentation not based on historical facts are “forward - looking statements” within the meani ng of the federal securities laws. Such forward - looking statements involve known and unknown risks and uncertainties that are difficult to predict

March 25, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 25, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 24, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 24, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 24, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 24, 2026 EX-99.1

Trian and General Catalyst Agree to Increase Merger Consideration to $52.00 per Share in Cash for Janus Henderson Group plc and Have Made the Only Actionable Proposal Amended Merger Agreement Represents a $3.00 All-Cash Price Increase; 25% Premium to

Exhibit 99.1 Trian and General Catalyst Agree to Increase Merger Consideration to $52.00 per Share in Cash for Janus Henderson Group plc and Have Made the Only Actionable Proposal Amended Merger Agreement Represents a $3.00 All-Cash Price Increase; 25% Premium to Unaffected Share Price; Parties Committed to Closing by Mid-2026 Special Committee Determines that Victory Capital’s Revised Unsolicited

March 24, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 24, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 24, 2026 Commission File Nu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 24, 2026 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 98-1376360 (State or other jur

March 24, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 24, 2026 EX-2.1

AMENDMENT NO. 1 TO AGREEMENT AND PLAN OF MERGER

Exhibit 2.1 Execution Version AMENDMENT NO. 1 TO AGREEMENT AND PLAN OF MERGER This Amendment No. 1, dated as of March 24, 2026 (this “Amendment”), to the Agreement and Plan of Merger (the “Agreement”), dated as of December 21, 2025, is entered into by and among Jupiter Company Limited, a company incorporated in Jersey (the “Parent”), Jupiter Merger Sub Limited, a company incorporated in Jersey and

March 19, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 19, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 18, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 17, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 11, 2026 DEFM14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Defi

March 11, 2026 EX-99.(C)(IX)

114:151:197 255:255:255 0:0:0 Brand Colors A. 240:235:230 167:162:157 114:115:117 Brand Grays B. 220:220:224 187:187:191 Background Grays C. 253:243:173 184:208:245 242:203:231 153:224:217 245:208:206 198:233:189 Table Highlight D. E. 0:0:0 114:115:1

Exhibit 99.(c)(ix) 114:151:197 255:255:255 0:0:0 Brand Colors A. 240:235:230 167:162:157 114:115:117 Brand Grays B. 220:220:224 187:187:191 Background Grays C. 253:243:173 184:208:245 242:203:231 153:224:217 245:208:206 198:233:189 Table Highlight D. E. 0:0:0 114:115:117 Table Borders F. Functional Data Colors G. 194:23:10 243:196:63 57:128:37 Primary Sequence 9:44:97 114:151:197 166:66:140 21:151

March 11, 2026 SC 13E3/A

As filed with the Securities and Exchange Commission on March 11, 2026 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13E-3 RULE 13E-3 TRANSACTION STATEMENT UNDER SECTION 13(E) OF THE SECURITIES ACT OF 1934 (Amendment No. 2)

As filed with the Securities and Exchange Commission on March 11, 2026 SECURITIES AND EXCHANGE COMMISSION Washington, D.

March 11, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 11, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 11, 2026 EX-99.(C)(X)

114:151:197 255:255:255 0:0:0 Brand Colors A. 240:235:230 167:162:157 114:115:117 Brand Grays B. 220:220:224 187:187:191 Background Grays C. 253:243:173 184:208:245 242:203:231 153:224:217 245:208:206 198:233:189 Table Highlight D. E. 0:0:0 114:115:1

Exhibit 99.(c)(x) 114:151:197 255:255:255 0:0:0 Brand Colors A. 240:235:230 167:162:157 114:115:117 Brand Grays B. 220:220:224 187:187:191 Background Grays C. 253:243:173 184:208:245 242:203:231 153:224:217 245:208:206 198:233:189 Table Highlight D. E. 0:0:0 114:115:117 Table Borders F. Functional Data Colors G. 194:23:10 243:196:63 57:128:37 Primary Sequence 9:44:97 114:151:197 166:66:140 21:151:

March 11, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 3, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 2, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

February 27, 2026 PRER14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1)

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 1

February 27, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

February 27, 2026 SC 13E3/A

As filed with the Securities and Exchange Commission on February 27, 2026 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13E-3 RULE 13E-3 TRANSACTION STATEMENT UNDER SECTION 13(E) OF THE SECURITIES ACT OF 1934 (Amendment No. 1)

As filed with the Securities and Exchange Commission on February 27, 2026 SECURITIES AND EXCHANGE COMMISSION Washington, D.

February 27, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

February 25, 2026 EX-19.1

Approval procedure for JHG Board of Directors (including the Chief Executive Officer)

Exhibit 19.1 Share Trading Policy Last Review Date: October 29, 2025 Contents 1 Overview 1 1.1 Purpose 1 1.2 Policy Statement 1 1.3 Definition of Material, Non-Public Information 2 1.4 Persons Subject to this Policy 2 1.5 Roles and Responsibilities 3 1.6 Compliance with Insider Trading Laws 3 1.7 Escalation Procedures 4 2 Definitions 4 3 Additional Procedures 5 3.1 Account Disclosures 5 3.2 Pre-Cl

February 25, 2026 EX-21.1

Percentage of

Exhibit 21.1 List of Subsidiaries The following is a list of subsidiaries included in our consolidated financial statements and the state or country of incorporation of each: Organization Percentage of ownership State or other jurisdiction of ownership Alphagen Capital Limited 100 UK Gartmore Investment Management Limited 100 UK Henderson Equity Partners Funds Limited 100 Jersey (Channel Islands)

February 25, 2026 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001-38103 JANUS HE

January 30, 2026 EX-99.(C)(III)

2 DRAFT Preliminary – Subject to Refinement Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in connection with

Exhibit 99.(c)(iii) Highly Confidential & Proprietary December 4, 2025 Project Jewel Discussion Materials Goldman Sachs & Co. DRAFT Preliminary – Subject to Refinement 2 DRAFT Preliminary – Subject to Refinement Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) i

January 30, 2026 EX-99.(C)(VI)

2 Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in connection with an informational presentation which Goldma

Exhibit 99.(c)(vi) December 15, 2025 Project Jewel – Updated Illustrative Sources & Uses Goldman Sachs & Co. DRAFT Preliminary – Subject to Refinement 2 Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in connection with an informational presentation which Goldm

January 30, 2026 EX-FILING FEES

Table 1: Transaction Valuation

Calculation of Filing Fee Tables Table 1: Transaction Valuation Transaction Valuation Fee Rate Amount of Filing Fee Fees to be Paid 1 $ 7,671,657,207.

January 30, 2026 EX-99.(C)(V)

2 DRAFT Preliminary – Subject to Refinement Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in connection with

Exhibit 99.(c)(v) Highly Confidential & Proprietary December 11, 2025 Project Jewel Discussion Materials Goldman Sachs & Co. DRAFT Preliminary – Subject to Refinement 2 DRAFT Preliminary – Subject to Refinement Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in

January 30, 2026 EX-99.(D)(VIII)

LIMITED GUARANTEE

  Exhibit 99.(d)(viii)   EXECUTION VERSION   LIMITED GUARANTEE   This LIMITED GUARANTEE, dated as of December 21, 2025 (this “Limited Guarantee”), by Qatar Holding LLC (the “Guarantor”), in favor of Janus Henderson Group plc, a public limited company organized under the Laws of Jersey (the “Guaranteed Party”). Reference is also made to the other Limited Guarantees of even date herewith delivered t

January 30, 2026 EX-99.(C)(VII)

2 DRAFT Preliminary – Subject to Refinement Institution Refinitiv Style Position Entry Date1 % OS Shares (mm) Cost Basis2 Unrealized Gain at $46.00 (Original Offer) Trian Hedge Fund Q2 '20 20.6 % 31.9 $ 29.49 56.0 % Vanguard Index Q3 '09 8.9 13.8 31.

Exhibit 99.(c)(vii) Highly Confidential & Proprietary December 16, 2025 Project Jewel Discussion Materials Goldman Sachs & Co. DRAFT Preliminary – Subject to Refinement 2 DRAFT Preliminary – Subject to Refinement Institution Refinitiv Style Position Entry Date1 % OS Shares (mm) Cost Basis2 Unrealized Gain at $46.00 (Original Offer) Trian Hedge Fund Q2 '20 20.6 % 31.9 $ 29.49 56.0 % Vanguard Index

January 30, 2026 EX-99.(B)(III)

Jupiter Company Limited Jupiter Borrower, Inc. c/o Trian Fund Management, L.P. 280 Park Avenue, 41st Floor New York, NY 10017

Exhibit 99.(b)(iii) Execution Version Jupiter Company Limited Jupiter Borrower, Inc. c/o Trian Fund Management, L.P. 280 Park Avenue, 41st Floor New York, NY 10017 January 21, 2026 JPMORGAN CHASE BANK, N.A. 270 Park Avenue New York, New York 10017 CITIGROUP GLOBAL MARKETS INC. 388 Greenwich Street New York, New York 10013 BANK OF AMERICA, N.A. BOFA SECURITIES, INC One Bryant Park New York, New Yor

January 30, 2026 EX-99.(C)(IV)

2 DRAFT Preliminary – Subject to Refinement Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in connection with

Exhibit 99.(c)(iv) Highly Confidential & Proprietary December 10, 2025 Project Jewel Discussion Materials Goldman Sachs & Co. DRAFT Preliminary – Subject to Refinement 2 DRAFT Preliminary – Subject to Refinement Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) i

January 30, 2026 EX-99.(D)(VII)

LIMITED GUARANTEE

  Exhibit 99.(d)(vii)   EXECUTION VERSION   LIMITED GUARANTEE    This LIMITED GUARANTEE, dated as of December 21, 2025 (this “Limited Guarantee”), by the Person listed on Schedule A hereto (the “Guarantor”), in favor of Janus Henderson Group plc, a public limited company organized under the Laws of Jersey (the “Guaranteed Party”). Reference is also made to the other Limited Guarantees of even date

January 30, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported):January 30, 2026 Commission File N

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported):January 30, 2026 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands (State or other jurisdiction

January 30, 2026 EX-99.1

Janus Henderson Group plc Reports Fourth Quarter and Full-Year 2025 Results

Exhibit 99.1 Janus Henderson Group plc Reports Fourth Quarter and Full-Year 2025 Results ● Solid investment performance, with 65%, 65%, 65%, and 67% of assets under management (“AUM”) outperforming relevant benchmarks on a one-, three-, five-, and 10-year basis, respectively, as of December 31, 2025 ● AUM of US$493 billion as of December 31, 2025, an increase of 30% year over year ● Fourth quarter

January 30, 2026 PREM14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defi

January 30, 2026 EX-99.(B)(II)

BANK OF AMERICA, N.A. BOFA SECURITIES, INC One Bryant Park New York, New York 10036

Exhibit 99.(b)(ii) Execution Version JPMORGAN CHASE BANK, N.A. 270 Park Avenue New York, New York 10017 CITIGROUP GLOBAL MARKETS INC. 388 Greenwich Street New York, New York 10013 BANK OF AMERICA, N.A. BOFA SECURITIES, INC One Bryant Park New York, New York 10036 JEFFERIES FINANCE LLC 520 Madison Avenue New York, New York 10022 MUFG BANK, LTD. 1221 Avenue of the Americas New York, NY 10020 SUMITOM

January 30, 2026 EX-99.(D)(IV)

[Signature Pages Follow]

Exhibit 99.(d)(iv) EXECUTION VERSION December 21, 2025 Jupiter Company Limited c/o Trian Fund Management, L.P. 280 Park Avenue 41st Floor New York, NY 10017 Re: Equity Financing Commitment Ladies and Gentlemen: Reference is made to the Agreement and Plan of Merger, dated as of the date hereof (as amended, supplemented or otherwise modified from time to time in accordance with its terms, the “Merge

January 30, 2026 EX-99.(D)(VI)

LIMITED GUARANTEE

  Exhibit 99.(d)(vi)   EXECUTION VERSION   LIMITED GUARANTEE    This LIMITED GUARANTEE, dated as of December 21, 2025 (this “Limited Guarantee”), by each Person listed on Schedule A hereto (each a “Guarantor” and, collectively, the “Guarantors”), in favor of Janus Henderson Group plc, a public limited company organized under the Laws of Jersey (the “Guaranteed Party”). Reference is also made to th

January 30, 2026 EX-FILING FEES

Table 1: Transaction Valuation

Calculation of Filing Fee Tables Table 1: Transaction Valuation Proposed Maximum Aggregate Value of Transaction Fee Rate Amount of Filing Fee Fees to be Paid 1 $ 7,671,657,207.

January 30, 2026 EX-99.(C)(II)

Disclaimer DRAFT Preliminary - Subject to Refinement INVESTMENT I BANKING These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the "Special Committee") of Jewel (the "Company")

Exhibit 99.(c)(ii) Project Jewel Discussion Materials Goldman Sachs & Co. December 2, 2025 DRAFT Preliminary - Subject to Refinement INVESTMENT I BANKING Disclaimer DRAFT Preliminary - Subject to Refinement INVESTMENT I BANKING These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the "Special Committee") of Jewel (the "Compan

January 30, 2026 EX-99.(D)(V)

[Signature Pages Follow]

  Exhibit 99.(d)(v)   EXECUTION VERSION   December 21, 2025   Jupiter Company Limited  c/o Trian Fund Management, L.P.  280 Park Avenue  41st Floor  New York, NY 10017   Re: Equity Financing Commitment   Ladies and Gentlemen:   Reference is made to the Agreement and Plan of Merger, dated as of the date hereof (as amended, supplemented or otherwise modified from time to time in accordance with its

January 30, 2026 SC 13E3

As filed with the Securities and Exchange Commission on January 30, 2026 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13E-3 RULE 13E-3 TRANSACTION STATEMENT UNDER SECTION 13(E) OF THE SECURITIES ACT OF 1934

As filed with the Securities and Exchange Commission on January 30, 2026 SECURITIES AND EXCHANGE COMMISSION Washington, D.

January 30, 2026 EX-99.(C)(I)

Disclaimer DRAFT Preliminary - Subject to Refinement INVESTMENT I BANKING These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the "Special Committee") of Jewel (the "Company")

Exhibit 99.(c)(i) Project Jewel Discussion Materials Goldman Sachs & Co. December 1 , 2025 DRAFT Preliminary - Subject to Refinement INVESTMENT I BANKING Disclaimer DRAFT Preliminary - Subject to Refinement INVESTMENT I BANKING These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the "Special Committee") of Jewel (the "Compan

January 30, 2026 EX-99.(C)(VIII)

2 Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in connection with an informational presentation which Goldma

Exhibit 99.(c)(viii) December 21, 2025 Project Jewel Discussion Materials Goldman Sachs & Co. 2 Disclaimer These materials have been prepared by Goldman Sachs on a confidential basis for presentation solely to the special committee (the “Special Committee”) of Jewel (the “Company”) in connection with an informational presentation which Goldman Sachs is making to the Special Committee. These materi

December 29, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

December 22, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

December 22, 2025 EX-2.1

AGREEMENT AND PLAN OF MERGER JUPITER COMPANY LIMITED, JUPITER MERGER SUB LIMITED, JANUS HENDERSON GROUP PLC Dated as of December 21, 2025 Table of Contents

Exhibit 2.1 EXECUTION VERSION AGREEMENT AND PLAN OF MERGER among JUPITER COMPANY LIMITED, JUPITER MERGER SUB LIMITED, and JANUS HENDERSON GROUP PLC Dated as of December 21, 2025 Table of Contents Page Article I THE MERGER Section 1.1 The Merger 2 Section 1.2 Closing 2 Section 1.3 Effective Time 2 Section 1.4 Effects of the Merger 3 Section 1.5 Surviving Company Constituent Documents 3 Section 1.6

December 22, 2025 EX-2.1

AGREEMENT AND PLAN OF MERGER JUPITER COMPANY LIMITED, JUPITER MERGER SUB LIMITED, JANUS HENDERSON GROUP PLC Dated as of December 21, 2025 Table of Contents

Exhibit 2.1 EXECUTION VERSION AGREEMENT AND PLAN OF MERGER among JUPITER COMPANY LIMITED, JUPITER MERGER SUB LIMITED, and JANUS HENDERSON GROUP PLC Dated as of December 21, 2025 Table of Contents Page Article I THE MERGER Section 1.1 The Merger 2 Section 1.2 Closing 2 Section 1.3 Effective Time 2 Section 1.4 Effects of the Merger 3 Section 1.5 Surviving Company Constituent Documents 3 Section 1.6

December 22, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

December 22, 2025 EX-99.1

Janus Henderson Group plc to be Acquired by Trian Fund Management and General Catalyst for $7.4 Billion Janus Henderson Shareholders to Receive $49.00 per Share in Cash Transaction Represents a Premium of 18% to the Unaffected Closing Price on Octobe

Exhibit 99.1 Janus Henderson Group plc to be Acquired by Trian Fund Management and General Catalyst for $7.4 Billion Janus Henderson Shareholders to Receive $49.00 per Share in Cash Transaction Represents a Premium of 18% to the Unaffected Closing Price on October 24, 2025 Significant Long-Term Investment to Be Made in Product Offerings, Client Services, Technology, and Talent LONDON, NEW YORK, SA

December 22, 2025 EX-10.1

VOTING AND ROLLOVER AGREEMENT

Exhibit 10.1 EXECUTION VERSION VOTING AND ROLLOVER AGREEMENT This VOTING AND ROLLOVER AGREEMENT (this “Agreement”), dated as of December 21, 2025, is entered into by and among Janus Henderson Group plc, a company incorporated in Jersey (the “Company”), the stockholder of the Company listed on Schedule A hereto (the “Stockholder”), Jupiter Topco LLC, a Jersey limited liability company (“Topco”), Ju

December 22, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

December 22, 2025 EX-10.1

VOTING AND ROLLOVER AGREEMENT

Exhibit 10.1 EXECUTION VERSION VOTING AND ROLLOVER AGREEMENT This VOTING AND ROLLOVER AGREEMENT (this “Agreement”), dated as of December 21, 2025, is entered into by and among Janus Henderson Group plc, a company incorporated in Jersey (the “Company”), the stockholder of the Company listed on Schedule A hereto (the “Stockholder”), Jupiter Topco LLC, a Jersey limited liability company (“Topco”), Ju

December 22, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 22, 2025 (December 21, 2

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 22, 2025 (December 21, 2025) Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 98-1376

December 22, 2025 EX-99.1

Janus Henderson Group plc to be Acquired by Trian Fund Management and General Catalyst for $7.4 Billion Janus Henderson Shareholders to Receive $49.00 per Share in Cash Transaction Represents a Premium of 18% to the Unaffected Closing Price on Octobe

Exhibit 99.1 Janus Henderson Group plc to be Acquired by Trian Fund Management and General Catalyst for $7.4 Billion Janus Henderson Shareholders to Receive $49.00 per Share in Cash Transaction Represents a Premium of 18% to the Unaffected Closing Price on October 24, 2025 Significant Long-Term Investment to Be Made in Product Offerings, Client Services, Technology, and Talent LONDON, NEW YORK, SA

December 22, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 22, 2025 (December 21, 2

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 22, 2025 (December 21, 2025) Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 98-1376

October 30, 2025 EX-99.1

Janus Henderson Group plc Reports Third Quarter 2025 Results

Exhibit 99.1 Janus Henderson Group plc Reports Third Quarter 2025 Results ● Solid long-term investment performance, with 74%, 64%, and 65% of assets under management (“AUM”) outperforming relevant benchmarks on a three-, five-, and 10-year basis, respectively, as of September 30, 2025 ● AUM of US$484 billion as of September 30, 2025, an increase of 27% year over year and 6% quarter over quarter ●

October 30, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 30, 2025 Commission File

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 30, 2025 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands (State or other jurisdiction

October 30, 2025 EX-10.1

WITHOUT PREJUDICE SUBJECT TO CONTRACT RETIREMENT AGREEMENT

Exhibit 10.1 WITHOUT PREJUDICE SUBJECT TO CONTRACT RETIREMENT AGREEMENT DATE: August 15, 2025 PARTIES: (1) You: Roger Thompson of [***] (2) The Company: Janus Henderson Administration UK Limited (company number 00290577) whose registered office is at 201 Bishopsgate, London EC2M 3AE WHEREAS (1) The Company is duly authorised to enter into this Agreement on its own behalf and as agent for any Group

October 30, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the transition period from to Commission File Number 001-38103

October 27, 2025 EX-99.1

1

Exhibit 99.1 October 27, 2025 Janus Henderson Group plc Confirms Acquisition Proposal from Trian and General Catalyst LONDON, October 27, 2025 (BUSINESS WIRE) - Janus Henderson Group plc (NYSE: JHG) (“Janus Henderson” or the “Company”), announced that it has received a letter outlining a non-binding acquisition proposal (the “Proposal”) submitted jointly by Trian Fund Management, L.P. and its affi

October 27, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 27, 2025 Commission File

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 27, 2025 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 001-38103 98-1376360 (State

August 18, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 15, 2025 JANUS HENDERSON G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 15, 2025 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 001-38103 98-1376360 (State or other jurisdiction of (Commissi

August 18, 2025 EX-99.1

Sukh Grewal To Succeed Roger Thompson as Janus Henderson Chief Financial Officer Grewal will retain role as Head of Strategy & Corporate Development

Exhibit 99.1 Sukh Grewal To Succeed Roger Thompson as Janus Henderson Chief Financial Officer Grewal will retain role as Head of Strategy & Corporate Development LONDON – August 18, 2025 – Janus Henderson Group plc (NYSE: JHG, “Janus Henderson,” or “the firm”) today announced that Sukh Grewal, in addition to his current role as Head of Strategy & Corporate Development, has been appointed Chief Fin

July 31, 2025 EX-10.3

Form of US DIP Share Unit (RSU) Award Agreement for CEO special award granted under the Janus Henderson Group plc 2022 Deferred Incentive Plan effective May 12, 2025

Exhibit 10.3 JANUS HENDERSON GROUP PLC DEFERRED INCENTIVE AWARD US – DIP SHARE UNIT (RSU) AWARD AGREEMENT CEO SPECIAL AWARD Janus Henderson Group plc (the “Company”) grants to Ali Dibadj (the “Grantee”), effective as of May 12, 2025 (the “Grant Date”), a deferred incentive award in the form of Share Units (the “DIP Share Unit Award”) as described below, subject to the terms and conditions set fort

July 31, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the transition period from to Commission File Number 001-38103 JANU

July 31, 2025 EX-10.2

Form of US DIP Performance-Based Share Unit (PSU) Award Agreement for CEO special award granted under the Janus Henderson Group plc 2022 Deferred Incentive Plan effective May 12, 2025

Exhibit 10.2 JANUS HENDERSON GROUP PLC DEFERRED INCENTIVE AWARD US – DIP PERFORMANCE-BASED SHARE UNIT (PSU) AWARD AGREEMENT CEO SPECIAL AWARD Janus Henderson Group plc (the “Company”) grants to Ali Dibadj (the “Grantee”), effective as of May 12, 2025 (the “Grant Date”), a deferred incentive award in the form of performance-based Share Units (the “DIP PSU Award”) as described below, subject to the

July 31, 2025 EX-10.4

Settlement Agreement dated May 16, 2025, between Janus Henderson Administration UK Limited and James Lowry

Exhibit 10.4 WITHOUT PREJUDICE SUBJECT TO CONTRACT SETTLEMENT AGREEMENT DATE: May 16, 2025 PARTIES: (1) You: James Lowry (2) The Company: Janus Henderson Administration UK Limited (company number 00290577) whose registered office is at 201 Bishopsgate, London EC2M 3AE WHEREAS (1) The Company is duly authorised to enter into this Agreement on its own behalf and as agent for any Group Company. (2) W

July 31, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2025 Commission File Num

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2025 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands (State or other jurisdiction of

July 31, 2025 EX-10.1

Employment Agreement dated May 9, 2025, between Janus Henderson Investors US LLC and Ali Dibadj

Exhibit 10.1 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (this “Agreement”) is made this May 9, 2025, by and between Janus Henderson Investors US LLC (“JHIUS”), a Delaware limited liability company, as employing entity, and Janus Henderson Group plc (“JHG”, and together with JHIUS, the “Company”), and Ali Dibadj (the “Executive”). WHEREAS, (i) JHG previously entered into an employment offer let

July 31, 2025 EX-99.1

Janus Henderson Group plc Reports Second Quarter 2025 Results

Exhibit 99.1 Janus Henderson Group plc Reports Second Quarter 2025 Results ● Solid investment performance, with 72%, 76%, 67%, and 72% of assets under management (“AUM”) outperforming relevant benchmarks on a one-, three-, five-, and 10-year basis, respectively, as of June 30, 2025 ● AUM of US$457 billion as of June 30, 2025, an increase of 27% year over year and 23% quarter over quarter ● Second

June 23, 2025 11-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 11-K FOR ANNUAL REPORTS OF EMPLOYEE STOCK REPURCHASE SAVINGS AND SIMILAR PLANS PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 11-K FOR ANNUAL REPORTS OF EMPLOYEE STOCK REPURCHASE SAVINGS AND SIMILAR PLANS PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 ☒ ANNUAL REPORT PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the year ended December 31, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 15 (d) OF THE SECURITIES EXCHANG

May 16, 2025 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2025 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 001-38103 98-1376360 (State or other jurisdiction of (Commission

May 9, 2025 8-K

Financial Statements and Exhibits, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2025 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 98-1376360 (State or other jurisd

May 2, 2025 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 30, 2025 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 001-38103 98-1376360 (State or other jurisdiction of (Commissio

May 1, 2025 EX-99.1

Janus Henderson Group plc Reports First Quarter 2025 Results

Exhibit 99.1 Janus Henderson Group plc Reports First Quarter 2025 Results ● Solid investment performance, with 77%, 65%, and 73% of assets under management (“AUM”) outperforming relevant benchmarks on a three-, five-, and 10-year basis, respectively, as of March 31, 2025 ● AUM of US$373 billion as of March 31, 2025, an increase of 6% year over year ● First quarter 2025 net inflows of US$2.0 billio

May 1, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the transition period from to Commission File Number 001-38103 JAN

May 1, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 1, 2025 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands (State or other jurisdiction of i

April 8, 2025 EX-99.1

Guardian and Janus Henderson Announce Multifaceted, Strategic Partnership

Exhibit 99.1 Guardian and Janus Henderson Announce Multifaceted, Strategic Partnership · Janus Henderson will manage the $45 billion investment grade public fixed income asset portfolio for Guardian’s general account, becoming Guardian’s investment grade public fixed income asset manager · Guardian will receive equity warrants and other economic consideration, supporting a shared goal of accelerat

April 8, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 8, 2025 Commission File Num

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 8, 2025 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 98-1376360 (State or other juri

April 8, 2025 EX-4.1

Form of Warrant to Purchase Ordinary Shares

Exhibit 4.1 FINAL FORM THIS WARRANT AND THE SECURITIES ISSUABLE UPON THE EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”). THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, HYPOTHECATED, OR OTHERWISE TRANSFERRED EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE ACT, OR AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY THAT REGISTRATION

March 21, 2025 ARS

ARS

INVESTING IN A BRIGHTER FUTURE TOGETHERJanus Henderson Group plc Annual Report 2024 Page 2 ABOUT US Janus Henderson’s mission is to help clients define and achieve superior financial outcomes through differentiated insights, disciplined investments, and world-class service.

March 21, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )

JANUS HENDERSON GROUP PLC - DEFA 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

March 21, 2025 DEF 14A

MESSAGE FROM OUR BOARD CHAIR NOTICE OF 2025 ANNUAL GENERAL MEETING OF SHAREHOLDERS PROXY SUMMARY PROPOSAL 1 ELECTION OF DIRECTORS CORPORATE GOVERNANCE BOARD COMPENSATION RESPONSIBILITY PROPOSAL 2 ADVISORY SAY-ON-PAY VOTE ON EXECUTIVE COMPENSATION EXE

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

February 28, 2025 PRE 14A

MESSAGE FROM OUR BOARD CHAIR NOTICE OF 2025 ANNUAL GENERAL MEETING OF SHAREHOLDERS PROXY SUMMARY PROPOSAL 1 ELECTION OF DIRECTORS CORPORATE GOVERNANCE BOARD COMPENSATION RESPONSIBILITY PROPOSAL 2 ADVISORY SAY-ON-PAY VOTE ON EXECUTIVE COMPENSATION EXE

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

February 27, 2025 EX-10.11

Service Agreement between Henderson Administrative Limited and James R. Lowry, effective from May 21, 2021* **

Exhibit 10.11 Ref: RW/James Lowry 21 May 2021 Dear James I am pleased to confirm our offer to you to join Henderson Administration Limited (the Company) on the following terms, subject to: ● proof that you are entitled to work in the United Kingdom; ● the Company’s satisfaction with the outcome of reference, criminal records and other pre- employment checks as required by the Company. For the avoi

February 27, 2025 EX-10.14

Janus Henderson Group Global Remuneration Policy Statement* **

Exhibit 10.14 Global Remuneration Policy Statement (“GRPS") Last Review Date: February 2025 Contents 1 Overview 1 1.1 Policy Statement 1 1.2 Key principles 1 1.3 Scope 6 1.4 Roles and Responsibilities 6 1.5 References 7 1.6 Review Schedule 8 1.7 Escalation Requirements 8 2 Definitions 8 1 Overview 1.1 Policy Statement Janus Henderson Group plc (the “Company”) operates a single Remuneration Policy

February 27, 2025 EX-19.1

Janus Henderson Group plc Share Trading Policy**

Exhibit 19.1 Share Trading Policy Last Review Date: October 29, 2024 Contents 1 Overview 1 1.1 Purpose 1 1.2 Policy Statement 1 1.3 Definition of Material, Non-Public Information 2 1.4 Persons Subject to this Policy 2 1.5 Roles and Responsibilities 3 1.6 Compliance with Insider Trading Laws 3 1.7 Escalation Procedures 4 2 Definitions 4 3 Additional Procedures 5 3.1 Account Disclosures 5 3.2 Pre-Cl

February 27, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001-38103 JANUS HE

February 27, 2025 EX-21.1

List of the Subsidiaries of the company prepared pursuant to Item 601(b)(21) of Regulation S-K**

Exhibit 21.1 List of Subsidiaries The following is a list of subsidiaries included in our consolidated financial statements and the state or country of incorporation of each: Organization Percentage of ownership State or other jurisdiction of ownership Alphagen Capital Limited 100 UK Gartmore Investment Management Limited 100 UK Gartmore Services Limited 100 Jersey (Channel Islands) Henderson Equi

February 25, 2025 424B3

Janus Henderson US (Holdings) Inc. Offer to Exchange Up to $400,000,000 5.450% Senior Notes due 2034 (the “Outstanding Notes”) for up to $400,000,000 5.450% Senior Notes due 2034 (the “New Notes”) that have been registered under the Securities Act of

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(3)  Registration No. 333-283305 PROSPECTUS Janus Henderson US (Holdings) Inc. Offer to Exchange Up to $400,000,000 5.450% Senior Notes due 2034 (the “Outstanding Notes”) for up to $400,000,000 5.450% Senior Notes due 2034 (the “New Notes”) that have been registered under the Securities Act of 1933 (the “Securities Act”) We are offering to exchange u

February 24, 2025 CORRESP

JANUS HENDERSON GROUP PLC 201 Bishopsgate London, United Kingdom JANUS HENDERSON US (HOLDINGS) INC. 151 Detroit Street Denver, CO 80206

JANUS HENDERSON GROUP PLC 201 Bishopsgate London, United Kingdom EC2M3AE JANUS HENDERSON US (HOLDINGS) INC.

January 31, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 31, 2025 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands (State or other jurisdiction

January 31, 2025 EX-99.1

Janus Henderson Group plc Reports Fourth Quarter and Full-Year 2024 Results

Exhibit 99.1 Janus Henderson Group plc Reports Fourth Quarter and Full-Year 2024 Results ● Solid investment performance, with 65%, 72%, 55%, and 73% of assets under management (“AUM”) outperforming relevant benchmarks on a one-, three-, five-, and 10-year basis, respectively, as of December 31, 2024 ● AUM increased 13% year over year to US$378.7 billion as of December 31, 2024 ● Fourth quarter 202

January 21, 2025 S-4/A

As filed with the Securities and Exchange Commission on January 21, 2025

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on January 21, 2025 Registration Statement No.

January 21, 2025 EX-99.1

Letter of Transmittal

EXHIBIT 99.1 LETTER OF TRANSMITTAL JANUS HENDERSON US (HOLDINGS) INC. OFFER FOR ALL OUTSTANDING 5.450% SENIOR NOTES DUE 2034 IN EXCHANGE FOR 5.450% SENIOR NOTES DUE 2034 THAT HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, PURSUANT TO THE PROSPECTUS DATED , 2025 THE EXCHANGE OFFER WILL EXPIRE AT 5:00 P.M., NEW YORK CITY TIME, ON , 2025 (THE “EXPIRATION DATE”), UNLESS EXTENDED. T

January 21, 2025 CORRESP

Janus Henderson Group plc 201 Bishopsgate London, United Kingdom Janus Henderson US (Holdings) Inc. 151 Detroit Street Denver, CO 80206 January 21, 2025

Janus Henderson Group plc 201 Bishopsgate London, United Kingdom EC2M3AE Janus Henderson US (Holdings) Inc.

December 20, 2024 LETTER

LETTER

December 20, 2024 Michelle Rosenberg President Janus Henderson US (Holdings) Inc. 201 Bishopsgate London, United Kingdom EC2M3AE Ali Dibadj Chief Executive Officer Janus Henderson Group plc 151 Detroit Street Denver, CO 80206 Re: Janus Henderson US (Holdings) Inc. Janus Henderson Group plc Amendment 1 to Registration Statement on Form S-4 Filed December 13, 2024 File Nos. 333-283305 and 333-283305

December 13, 2024 CORRESP

Janus Henderson Group plc 201 Bishopsgate London, United Kingdom Janus Henderson US (Holdings) Inc. 151 Detroit Street Denver, CO 80206 December 13, 2024

Janus Henderson Group plc 201 Bishopsgate London, United Kingdom EC2M3AE Janus Henderson US (Holdings) Inc.

December 13, 2024 CORRESP

JANUS HENDERSON GROUP PLC 201 Bishopsgate London, United Kingdom JANUS HENDERSON US (HOLDINGS) INC. 151 Detroit Street Denver, CO 80206

JANUS HENDERSON GROUP PLC 201 Bishopsgate London, United Kingdom EC2M3AE JANUS HENDERSON US (HOLDINGS) INC.

December 13, 2024 S-4/A

As filed with the Securities and Exchange Commission on December 13, 2024

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on December 13, 2024 Registration Statement No.

December 6, 2024 SC 13G/A

BNTC / Benitec Biopharma Inc. / JANUS HENDERSON GROUP PLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 5* Name of Issuer: Benitec Biopharma Inc. Title of Class of Securities: Common Stock CUSIP Number: 08205P209 Date of Event Which Requires Filing of this Statement: 11/29/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is

December 3, 2024 LETTER

LETTER

December 2, 2024 Michelle Rosenberg President Janus Henderson US (Holdings) Inc. 151 Detroit Street Denver, CO 80206 Re: Janus Henderson US (Holdings) Inc. Registration Statement on Form S-4 Filed November 18, 2024 File No. 333-283305 Dear Michelle Rosenberg: We have conducted a limited review of your registration statement and have the following comments. Please respond to this letter by amending

November 18, 2024 EX-3.3

Certificate of Incorporation of Janus Henderson US (Holdings) Inc.

Exhibit 3.3 STATE OF DELAWARE CERTIFICATE OF AMENDMENT OF CERTIFICATE OF INCORPORATION The corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware does hereby certify: FIRST: That at a meeting of the Board of Directors of Janus Capital Group Inc. resolutions were duly adopted setting forth a proposed amendment of the Certificate of Incorporati

November 18, 2024 EX-22.1

List of Guarantors and Subsidiary Issuers of Guaranteed Securities.

Exhibit 22.1 List of Guarantors and Subsidiary Issuers of Guaranteed Securities The subsidiary of Janus Henderson Group plc identified in the table below has issued the debt securities listed opposite such subsidiary issuer. Janus Henderson Group plc has fully and unconditionally guaranteed all such securities. Subsidiary Issuer Guaranteed Securities Janus Henderson US (Holdings) Inc. 5.450% Senio

November 18, 2024 EX-3.4

Amended and Restated Bylaws of Janus Henderson US (Holdings) Inc.

Exhibit 3.4 AMENDED AND RESTATED BYLAWS OF JANUS CAPITAL GROUP INC. As amended and restated as of October 21, 2008 ARTICLE I Offices Section 1.      Registered Office. The registered office of the Corporation in the State of Delaware shall be at such location within the State of Delaware as shall from time to time be determined by the Board of Directors. Section 2.      Other Offices. The Corporat

November 18, 2024 EX-FILING FEES

Filing Fee table

Calculation of Filing Fee Tables S-4 JANUS HENDERSON GROUP PLC Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward Newly Registered Securities Fees to be Paid 1 Debt 5.

November 18, 2024 EX-25.1

Form T-1, Statement of Eligibility under the Trust Indenture Act of 1939, as amended, of The Bank of New York Mellon Trust Company, N.A., as trustee under the Indenture, dated September 10, 2024, for the 5.450% Senior Notes due 2034

Exhibit 25.1 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM T-1 STATEMENT OF ELIGIBILITY UNDER THE TRUST INDENTURE ACT OF 1939 OF A CORPORATION DESIGNATED TO ACT AS TRUSTEE ¨ CHECK IF AN APPLICATION TO DETERMINE ELIGIBILITY OF A TRUSTEE PURSUANT TO SECTION 305(b)(2) THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A. (Exact name of trustee as specified in its charter) California 95-357

November 18, 2024 S-4

As filed with the Securities and Exchange Commission on November 18, 2024

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on November 18, 2024 Registration Statement No.

November 14, 2024 SC 13G/A

FLEX / Flex Ltd. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Flex093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: FLEX LTD. Title of Class of Securities: Ordinary Shares CUSIP Number: Y2573F102 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule purs

November 14, 2024 SC 13G/A

EGRX / Eagle Pharmaceuticals, Inc. / JANUS HENDERSON GROUP PLC - JANUS CLOSEOUT Passive Investment

SC 13G/A 1 Eagle093024.txt JANUS CLOSEOUT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 8* Name of Issuer: Eagle Pharmaceuticals, Inc. Title of Class of Securities: Common Stock CUSIP Number: 269796108 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designat

November 14, 2024 SC 13G/A

ETNB / 89bio, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 3* Name of Issuer: MADRIGAL PHARMACEUTICALS, INC. Title of Class of Securities: Common Stock CUSIP Number: 282559103 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to which this Sched

November 14, 2024 SC 13G/A

TENX / Tenax Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Tenax093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: Tenax Therapeutics, Inc Title of Class of Securities: Common Stock CUSIP Number: 88032L605 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate t

November 14, 2024 SC 13G/A

OSIS / OSI Systems, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 OSISystems093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 8* Name of Issuer: OSI SYSTEMS, INC. Title of Class of Securities: Common Stock CUSIP Number: 671044105 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate th

November 14, 2024 SC 13G/A

FWONK / Liberty Media Corp. (New Liberty Formula One) Series C / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Libertymedia093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 6* Name of Issuer: LIBERTY MEDIA CORPORATION Title of Class of Securities: Series C Liberty Formula One Common Stock CUSIP Number: 531229755 Date of Event Which Requires Filing of this Statement: 9/30/2024 Ch

November 14, 2024 SC 13G

CZR / Caesars Entertainment, Inc. / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 Caesars093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: CAESARS ENTERTAINMENT INC Title of Class of Securities: Common Stock CUSIP Number: 12769G100 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the r

November 14, 2024 SC 13G/A

BLKB / Blackbaud, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 7* Name of Issuer: Blackbaud, Inc. Title of Class of Securities: Common Stock CUSIP Number: 09227Q100 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is filed. [

November 14, 2024 SC 13G/A

AVDL / Avadel Pharmaceuticals plc / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: AVADEL PHARMACEUTICALS Title of Class of Securities: Common Stock CUSIP Number: G29687103 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is f

November 14, 2024 SC 13G/A

BHVN / Biohaven Ltd. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Biohaven093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: Biohaven Ltd. Title of Class of Securities: Common Stock CUSIP Number: G1110E107 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule

November 14, 2024 SC 13G/A

TFX / Teleflex Incorporated / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Teleflex093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: TELEFLEX INCORPORATED Title of Class of Securities: Common Stock CUSIP Number: 879369106 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate

November 14, 2024 SC 13G/A

NGNE / Neurogene Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Neurogene093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: NEUROGENE INC. Title of Class of Securities: Common Stock CUSIP Number: 64135M105 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the ru

November 14, 2024 SC 13G/A

WD / Walker & Dunlop, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 WalkerDunlop093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 4* Name of Issuer: Walker & Dunlop, Inc. Title of Class of Securities: Common Stock CUSIP Number: 93148P102 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to design

November 14, 2024 SC 13G/A

ASND / Ascendis Pharma A/S - Depositary Receipt (Common Stock) / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Ascendis093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 4* Name of Issuer: Ascendis Pharma A/S Title of Class of Securities: American Depositary Shares CUSIP Number: 04351P101 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box t

November 14, 2024 SC 13G/A

MREO / Mereo BioPharma Group plc - Depositary Receipt (Common Stock) / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Mereo093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: MEREO BIOPHARMA GROUP PLC Title of Class of Securities: American Depositary Shares CUSIP Number: 589492107 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate bo

November 14, 2024 SC 13G/A

WEX / WEX Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Wex093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 9* Name of Issuer: WEX Inc. Title of Class of Securities: Common Stock CUSIP Number: 96208T104 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant

November 14, 2024 SC 13G/A

IDYA / IDEAYA Biosciences, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Ideaya093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: IDEAYA Biosciences, Inc. Title of Class of Securities: Common Stock CUSIP Number: 45166A102 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate

November 14, 2024 SC 13G/A

SXT / Sensient Technologies Corporation / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Sensient093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 8* Name of Issuer: Sensient Technologies Corporation Title of Class of Securities: Common Stock CUSIP Number: 81725T100 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box t

November 14, 2024 SC 13G

GPCR / Structure Therapeutics Inc. - Depositary Receipt (Common Stock) / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 Structure093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: STRUCTURE THERAPEUTICS INC Title of Class of Securities: American Depositary Shares CUSIP Number: 86366E106 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box t

November 14, 2024 SC 13G/A

SSNC / SS&C Technologies Holdings, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 SSC093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 8* Name of Issuer: SS&C TECHNOLOGIES HOLDINGS, INC. Title of Class of Securities: Common Stock CUSIP Number: 78467J100 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to desi

November 14, 2024 SC 13G/A

SRPT / Sarepta Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS CLOSEOUT Passive Investment

SC 13G/A 1 Sarepta093024.txt JANUS CLOSEOUT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 3* Name of Issuer: SAREPTA THERAPEUTICS, INC. Title of Class of Securities: Common Stock CUSIP Number: 803607100 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designa

November 14, 2024 SC 13G/A

ABEO / Abeona Therapeutics Inc. / JANUS HENDERSON GROUP PLC - JANUS CLOSEOUT Passive Investment

SC 13G/A 1 Abeona093024.txt JANUS CLOSEOUT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: ABEONA THERAPEUTICS INC. Title of Class of Securities: Common Stock CUSIP Number: 00289Y206 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate

November 14, 2024 SC 13G

HK:9688 / Zai Lab Limited / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 ZaiLab093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: ZAI LAB LTD Title of Class of Securities: American Depositary Shares CUSIP Number: G9887T116 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the ru

November 14, 2024 SC 13G/A

ORKA / Oruka Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS CLOSEOUT Passive Investment

SC 13G/A 1 oruka.arca09302024.txt JANUS CLOSEOUT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: Oruka Therapeutics, Inc. (formerly known as ARCA biopharma, Inc.) Title of Class of Securities: Common Stock CUSIP Number: 687604108 Date of Event Which Requires Filing of this Statement: 9/

November 14, 2024 SC 13G

CATX / Perspective Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 Perspective093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: PERSPECTIVE THERAPEUTICS INC Title of Class of Securities: Common Stock CUSIP Number: 46489V302 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designat

November 14, 2024 SC 13G/A

DTIL / Precision BioSciences, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Precision093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: Precision BioSciences, Inc. Title of Class of Securities: Common Stock CUSIP Number: 74019P207 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to des

November 14, 2024 SC 13G

ARMK / Aramark / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 Aramark093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: ARAMARK Title of Class of Securities: Common Stock CUSIP Number: 03852U106 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to wh

November 14, 2024 SC 13G/A

SKYE / Skye Bioscience, Inc. / JANUS HENDERSON GROUP PLC - JANUS CLOSEOUT Passive Investment

SC 13G/A 1 Skye093024.txt JANUS CLOSEOUT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: Skye Bioscience, Inc. Title of Class of Securities: Common Stock CUSIP Number: 83086J200 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the r

November 14, 2024 SC 13G/A

APLT / Applied Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Applied093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: APPLIED THERAPEUTICS INC Title of Class of Securities: Common Stock CUSIP Number: 03828A101 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designat

November 14, 2024 SC 13G/A

CTLT / Catalent, Inc. / JANUS HENDERSON GROUP PLC - JANUS CLOSEOUT Passive Investment

SC 13G/A 1 Catalent093024.txt JANUS CLOSEOUT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 6* Name of Issuer: Catalent, Inc. Title of Class of Securities: Common Stock CUSIP Number: 148806102 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule

November 14, 2024 SC 13G

PEPG / PepGen Inc. / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 Pepgen093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: PEPGEN INC Title of Class of Securities: Common Stock CUSIP Number: 713317105 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to

November 14, 2024 SC 13G/A

AKRO / Akero Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Akero093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 7* Name of Issuer: Akero Therapeutics, Inc. Title of Class of Securities: Common Stock CUSIP Number: 00973Y108 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate

November 14, 2024 SC 13G/A

SLNO / Soleno Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Soleno093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 3* Name of Issuer: SOLENO THERAPEUTICS, INC. Title of Class of Securities: Common Stock CUSIP Number: 834203309 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designat

November 14, 2024 SC 13G/A

ZD / Ziff Davis, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 3* Name of Issuer: ZIFF DAVIS, INC. Title of Class of Securities: Common Stock CUSIP Number: 48123V102 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is filed.

November 14, 2024 SC 13G/A

CMPX / Compass Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS CLOSEOUT Passive Investment

SC 13G/A 1 Compass093024.txt JANUS CLOSEOUT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: COMPASS THERAPEUTICS, INC. Title of Class of Securities: Common Stock CUSIP Number: 20454B104 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designa

November 14, 2024 SC 13G/A

ICUI / ICU Medical, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 ICUMedical093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 8* Name of Issuer: ICU MEDICAL, INC. Title of Class of Securities: Common Stock CUSIP Number: 44930G107 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate th

November 14, 2024 SC 13G/A

ST / Sensata Technologies Holding plc / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Sensata093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 7* Name of Issuer: SENSATA TECHNOLOGIES HOLDING PLC Title of Class of Securities: Ordinary Shares CUSIP Number: G8060N102 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box

November 14, 2024 SC 13G/A

LNTH / Lantheus Holdings, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Lantheus093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: LANTHEUS HOLDINGS, INC. Title of Class of Securities: Common Stock CUSIP Number: 516544103 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designat

November 14, 2024 SC 13G/A

LRMR / Larimar Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Larimar093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: LARIMAR THERAPEUTICS, INC. Title of Class of Securities: Common Stock CUSIP Number: 517125100 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to design

November 14, 2024 SC 13G/A

GDDY / GoDaddy Inc. / JANUS HENDERSON GROUP PLC - JANUS CLOSEOUT Passive Investment

SC 13G/A 1 Godaddy093024.txt JANUS CLOSEOUT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: GoDaddy Inc. Title of Class of Securities: Class A Common Stock CUSIP Number: 380237107 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the

November 14, 2024 SC 13G/A

MIRM / Mirum Pharmaceuticals, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Mirum093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: Mirum Pharmaceuticals, Inc. Title of Class of Securities: Common Stock CUSIP Number: 604749101 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designa

November 14, 2024 SC 13G/A

CRGX / CARGO Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Cargo093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: CARGO Therapeutics, Inc. Title of Class of Securities: Common Stock CUSIP Number: 14179K101 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate

November 14, 2024 EX-99.1

Joint Filing Agreement

EX-99.1 2 d887398dex991.htm EX-99.1 CUSIP NO. G4474Y214 13G Page 11 of 11 EXHIBIT 99.1 Joint Filing Agreement November 14, 2024 In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, Silchester International Investors LLP, Silchester Partners Limited, Silchester Continuation Limited and Stephen Charles Butt each hereby agree to the joint filing of this statement

November 14, 2024 SC 13G

NEO / NeoGenomics, Inc. / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 Neogenomics093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: NEOGENOMICS INC Title of Class of Securities: Common Stock CUSIP Number: 64049M209 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pu

November 14, 2024 SC 13G

IMNM / Immunome, Inc. / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: IMMUNOME INC Title of Class of Securities: Common Stock CUSIP Number: 45257U108 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is filed. [X]

November 14, 2024 SC 13G/A

JHG / Janus Henderson Group plc / Silchester International Investors LLP - SC 13G/A Passive Investment

SC 13G/A 1 d887398dsc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) Schedule 13G under the Securities Exchange Act of 1934 (Amendment No. 2) Janus Henderson Group plc (Name of Issuer) Common stock (Title of Class of Securities) G4474Y214 (CUSIP Number) September 30, 2024 Date of Event Which Requires Filing of the Statement Chec

November 14, 2024 SC 13G

RVTY / Revvity, Inc. / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 Revvity093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: REVVITY INC Title of Class of Securities: Common Stock CUSIP Number: 714046109 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant t

November 14, 2024 SC 13G/A

DOX / Amdocs Limited / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 7* Name of Issuer: AMDOCS LIMITED Title of Class of Securities: Ordinary Shares CUSIP Number: G02602103 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is filed.

November 14, 2024 SC 13G/A

IMUX / Immunic, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Immunic093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: Immunic, Inc. Title of Class of Securities: Common Stock CUSIP Number: 4525EP101 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule

November 14, 2024 SC 13G/A

CTMX / CytomX Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Cytomx093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: CytomX Therapeutics, Inc. Title of Class of Securities: Common Stock CUSIP Number: 23284F105 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designat

November 14, 2024 SC 13G/A

LXEO / Lexeo Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Lexeo093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: Lexeo Therapeutics, Inc. Title of Class of Securities: Common Stock CUSIP Number: 52886X107 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate

November 14, 2024 SC 13G/A

CCSI / Consensus Cloud Solutions, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Consensus093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 3* Name of Issuer: Consensus Cloud Solutions, Inc. Title of Class of Securities: Common Stock CUSIP Number: 20848V105 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to

November 14, 2024 SC 13G

ATRO / Astronics Corporation / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 Asure093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: ASURE SOFTWARE INC Title of Class of Securities: Common Stock CUSIP Number: 046433108 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursu

November 14, 2024 SC 13G/A

ARDX / Ardelyx, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Ardelyx093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 3* Name of Issuer: ARDELYX, INC. Title of Class of Securities: Common Stock CUSIP Number: 039697107 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule

November 14, 2024 SC 13G/A

GMED / Globus Medical, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 5* Name of Issuer: GLOBUS MEDICAL, INC. Title of Class of Securities: Class A Common Stock CUSIP Number: 379577208 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to which this Schedul

November 14, 2024 SC 13G

DYN / Dyne Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 Dyne093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: DYNE THERAPEUTICS INC Title of Class of Securities: Common Stock CUSIP Number: 26818M108 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pur

November 14, 2024 SC 13G

GB:RTO / Rentokil Initial plc / JANUS HENDERSON GROUP PLC - JANUS NEW Passive Investment

SC 13G 1 Rentokil093024.txt JANUS NEW UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: Rentokil Initial plc Title of Class of Securities: Common Stock CUSIP Number: G7494G105 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule

November 14, 2024 SC 13G/A

LGND / Ligand Pharmaceuticals Incorporated / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Ligand093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 5* Name of Issuer: LIGAND PHARMACEUTICALS INCORPORATED Title of Class of Securities: Common Stock CUSIP Number: 53220K504 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box t

November 14, 2024 SC 13G/A

FDMT / 4D Molecular Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 4D093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 3* Name of Issuer: 4D Molecular Therapeutics, Inc. Title of Class of Securities: Common Stock CUSIP Number: 35104E100 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to design

November 14, 2024 SC 13G/A

CSTM / Constellium SE / JANUS HENDERSON GROUP PLC - JANUS CLOSEOUT Passive Investment

SC 13G/A 1 Constellium093024.txt JANUS CLOSEOUT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 4* Name of Issuer: Constellium SE Title of Class of Securities: Ordinary Shares CUSIP Number: F21107101 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate th

November 14, 2024 SC 13G/A

SKIN / The Beauty Health Company / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Beauty093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 4* Name of Issuer: The Beauty Health Company Title of Class of Securities: Class A Common Stock CUSIP Number: 88331L108 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to

November 14, 2024 SC 13G/A

PCVX / Vaxcyte, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Vaxcyte093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 4* Name of Issuer: VAXCYTE, INC. Title of Class of Securities: Common Stock CUSIP Number: 92243G108 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule

November 14, 2024 SC 13G/A

BNTC / Benitec Biopharma Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 4* Name of Issuer: Benitec Biopharma Inc. Title of Class of Securities: Common Stock CUSIP Number: 08205P209 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is f

November 14, 2024 SC 13G/A

CMPR / Cimpress plc / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 10* Name of Issuer: Cimpress plc Title of Class of Securities: Ordinary Shares CUSIP Number: G2143T103 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is filed.

November 14, 2024 SC 13G/A

ETNB / 89bio, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 89bio093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 4* Name of Issuer: 89bio, Inc. Title of Class of Securities: Common Stock CUSIP Number: 282559103 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule purs

November 14, 2024 SC 13G/A

OABI / OmniAb, Inc. / JANUS HENDERSON GROUP PLC - JANUS AMENDMENT Passive Investment

SC 13G/A 1 Omniab093024.txt JANUS AMENDMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: OmniAb, Inc. Title of Class of Securities: Common Stock CUSIP Number: 68218J103 Date of Event Which Requires Filing of this Statement: 9/30/2024 Check the appropriate box to designate the rule pu

November 6, 2024 SC 13G

MNPR / Monopar Therapeutics Inc. / JANUS HENDERSON GROUP PLC - JANUS OWNS OVER 10 Passive Investment

SC 13G 1 Monopar103124.txt JANUS OWNS OVER 10 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: MONOPAR THERAPEUTICS INC Title of Class of Securities: Common Stock CUSIP Number: 61023L207 Date of Event Which Requires Filing of this Statement: 10/31/2024 Check the appropriate box to design

November 6, 2024 SC 13G/A

BNTC / Benitec Biopharma Inc. / JANUS HENDERSON GROUP PLC - JANUS OWNS OVER 10 Passive Investment

SC 13G/A 1 Benitec103124.txt JANUS OWNS OVER 10 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 3* Name of Issuer: Benitec Biopharma Inc. Title of Class of Securities: Common Stock CUSIP Number: 08205P209 Date of Event Which Requires Filing of this Statement: 10/31/2024 Check the appropriate box to design

October 31, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the transition period from to Commission File Number 001-38103

October 31, 2024 EX-99.1

Janus Henderson Group plc Reports Third Quarter 2024 Results

Exhibit 99.1 Janus Henderson Group plc Reports Third Quarter 2024 Results ● Solid investment performance, with 75%, 71%, 67%, and 85% of assets under management (“AUM”) outperforming relevant benchmarks on a one-, three-, five-, and 10-year basis, respectively, as of September 30, 2024 ● Consecutive quarters of net inflows with third quarter 2024 net inflows of US$0.4 billion ● Third quarter 2024

October 31, 2024 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 31, 2024 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands (State or other jurisdiction

October 25, 2024 SC 13G/A

BNTC / Benitec Biopharma Inc. / JANUS HENDERSON GROUP PLC - JANUS OWNS OVER 10 Passive Investment

SC 13G/A 1 Benitec102124.txt JANUS OWNS OVER 10 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: Benitec Biopharma Inc. Title of Class of Securities: Common Stock CUSIP Number: 08205P209 Date of Event Which Requires Filing of this Statement: 10/21/2024 Check the appropriate box to design

October 3, 2024 SC 13G

SLNO / Soleno Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS HENDERSON GROUP PLC OWNS 10.1% OF SOLENO THERAPEUTICS, INC. Passive Investment

SC 13G 1 Soleno093024.txt JANUS HENDERSON GROUP PLC OWNS 10.1% OF SOLENO THERAPEUTICS, INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: SOLENO THERAPEUTICS, INC. Title of Class of Securities: Common Stock CUSIP Number: 834203309 Date of Event Which Requires Filing of this Statement:

September 10, 2024 EX-4.2

Registration Rights Agreement, dated September 10, 2024, among Janus Henderson US (Holdings) Inc., as issuer, JHG, as guarantor, and Citigroup Global Markets Inc., BofA Securities, Inc. and Morgan Stanley & Co. LLC, as representatives, is hereby incorporated by reference from Exhibit 4.2 to JHG’s Current Report on Form 8-K, dated September 10, 2024 (File No. 001-38103)

Exhibit 4.2 Janus Henderson US (Holdings) Inc. Registration Rights Agreement $400,000,000 5.450% Senior Notes Due 2034 September 10, 2024 This Registration Rights Agreement dated September 10, 2024 (this “Agreement”) is entered into by and among Janus Henderson US (Holdings) Inc., a Delaware corporation (the “Issuer”), Janus Henderson Group plc, a public limited company incorporated under the laws

September 10, 2024 EX-4.1

Indenture, dated as of September 10, 2024, among Janus Henderson US (Holdings) Inc., as issuer, JHG, as guarantor, and The Bank of New York Mellon Trust Company, N.A., as trustee, is hereby incorporated by reference from Exhibit 4.1 to JHG’s Current Report on Form 8-K, dated September 10, 2024 (File No. 001-38103)

Exhibit 4.1 JANUS HENDERSON US (HOLDINGS) INC. as Issuer JANUS HENDERSON GROUP PLC as Guarantor and THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., as Trustee $400,000,000 5.450% SENIOR NOTES DUE 2034 SENIOR INDENTURE Dated as of September 10, 2024 TABLE OF CONTENTS Page Article 1 Definitions and Incorporation by Reference Section 1.01. Definitions 1 Section 1.02. Other Definitions 9 Section 1.03

September 10, 2024 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 10, 2024 (September 10, 2024) JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 001-38103 98-1376360 (State or other j

September 5, 2024 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 5, 2024 (September 5, 2024) JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 001-38103 98-1376360 (State or other jur

September 3, 2024 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 3, 2024 (September 3, 2024) JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 001-38103 98-1376360 (State or other jur

August 14, 2024 SC 13G

TENX / Tenax Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JHG PLC OWNS 9.9% Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: Tenax Therapeutics, Inc Title of Class of Securities: Common Stock CUSIP Number: 88032L605 Date of Event Which Requires Filing of this Statement: 8/8/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is f

August 14, 2024 SC 13G

SKYE / Skye Bioscience, Inc. / JANUS HENDERSON GROUP PLC - JHG PLC OWNS >5% Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: Skye Bioscience, Inc. Title of Class of Securities: Common Stock CUSIP Number: 83086J200 Date of Event Which Requires Filing of this Statement: 8/9/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is fil

August 12, 2024 8-K

Unregistered Sales of Equity Securities, Other Events, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2024 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 98-1376360 (State or other ju

August 12, 2024 EX-99.1

Janus Henderson Announces Acquisition of Global Private Credit Manager Victory Park Capital

EX-99.1 2 tm2421336d1ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 Janus Henderson Announces Acquisition of Global Private Credit Manager Victory Park Capital · Acquisition further expands Janus Henderson’s private credit and institutional capabilities · Victory Park Capital has a nearly two decade-long track record in asset-backed focused private credit · Victory Park Capital complements Janus Henderson’s

August 9, 2024 SC 13G/A

WEX / WEX Inc. / JANUS HENDERSON GROUP PLC - JANUS OWNS >10 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 8* Name of Issuer: WEX Inc. Title of Class of Securities: Common Stock CUSIP Number: 96208T104 Date of Event Which Requires Filing of this Statement: 7/31/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is filed. [X] Rule

August 9, 2024 SC 13G/A

CCSI / Consensus Cloud Solutions, Inc. / JANUS HENDERSON GROUP PLC - JANUS OWNS >10 Passive Investment

SC 13G/A 1 Consensus073124.txt JANUS OWNS >10 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 2* Name of Issuer: Consensus Cloud Solutions, Inc. Title of Class of Securities: Common Stock CUSIP Number: 20848V105 Date of Event Which Requires Filing of this Statement: 7/31/2024 Check the appropriate box to

August 5, 2024 SC 13G/A

LXEO / Lexeo Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS HENDERSON OWNS LEXEO Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: Lexeo Therapeutics, Inc. Title of Class of Securities: Common Stock CUSIP Number: 52886X107 Date of Event Which Requires Filing of this Statement: 7/25/2024 Check the appropriate box to designate the rule pursuant to which this Schedule is

August 1, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the transition period from to Commission File Number 001-38103 JANU

August 1, 2024 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 1, 2024 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands (State or other jurisdiction o

August 1, 2024 EX-99.1

Janus Henderson Group plc Reports Second Quarter 2024 Results

Exhibit 99.1 Janus Henderson Group plc Reports Second Quarter 2024 Results ● Solid investment performance, with 69%, 63%, 66%, and 84% of assets under management (“AUM”) outperforming relevant benchmarks on a one-, three-, five-, and 10-year basis, respectively, as of June 30, 2024 ● Second quarter 2024 net inflows of US$1.7 billion reflect net inflows in Intermediary and Institutional ● Second qu

July 11, 2024 SC 13G

MREO / Mereo BioPharma Group plc - Depositary Receipt (Common Stock) / JANUS HENDERSON GROUP PLC - JANUS HENDERSON OWNS 5 Passive Investment

SC 13G 1 JHBIFMereo070124.txt JANUS HENDERSON OWNS 5 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: Mereo BioPharma Group plc Title of Class of Securities: American Depositary Shares CUSIP Number: 589492107 Date of Event Which Requires Filing of this Statement: 7/1/2024 Check the appro

July 10, 2024 SC 13G

MIRM / Mirum Pharmaceuticals, Inc. / JANUS HENDERSON GROUP PLC - JANUS HENDERSON OWNS 10 Passive Investment

SC 13G 1 Mirum062824.txt JANUS HENDERSON OWNS 10 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: Mirum Pharmaceuticals, Inc. Title of Class of Securities: Common Stock CUSIP Number: 604749101 Date of Event Which Requires Filing of this Statement: 6/28/2024 Check the appropriate box to d

July 5, 2024 SC 13G/A

ABIO / ARCA biopharma, Inc. / JANUS HENDERSON GROUP PLC - JHG PLC (JHBIF) OWNS 10% Passive Investment

SC 13G/A 1 JHBIFArcaBiopharma070224.txt JHG PLC (JHBIF) OWNS 10% UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 1* Name of Issuer: ARCA BIOPHARMA, INC Title of Class of Securities: Common Stock CUSIP Number: 00211Y506 Date of Event Which Requires Filing of this Statement: 7/2/2024 Check the appropriate b

June 20, 2024 11-K

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 11-K FOR ANNUAL REPORTS OF EMPLOYEE STOCK REPURCHASE SAVINGS AND SIMILAR PLANS PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

Table of Contents SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 11-K FOR ANNUAL REPORTS OF EMPLOYEE STOCK REPURCHASE SAVINGS AND SIMILAR PLANS PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 ☒ ANNUAL REPORT PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the year ended December 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 15 (d) OF THE

June 10, 2024 SC 13G/A

AKRO / Akero Therapeutics, Inc. / JANUS HENDERSON GROUP PLC - JANUS HENDERSON OWNS 10.1% Passive Investment

SC 13G/A 1 Akero053124.txt JANUS HENDERSON OWNS 10.1% UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 6* Name of Issuer: Akero Therapeutics, Inc. Title of Class of Securities: Common Stock CUSIP Number: 00973Y108 Date of Event Which Requires Filing of this Statement: 5/31/2024 Check the appropriate box to

May 30, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 28, 2024 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 001-38103 98-1376360 (State or other jurisdiction of (Commission

May 22, 2024 SC 13G

CTMX / CytomX Therapeutics, Inc. / JANUS HENDERSON GROUP PLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: CytomX Therapeutics, Inc. Title of Class of Securities: Common Stock CUSIP Number: 23284F105 Date of Event Which Requires Filing of this Statement: 5/13/2024 Check the appropriate box to designate the rule pursuant to which this Schedule i

May 9, 2024 SC 13G

ABEO / Abeona Therapeutics Inc. / JANUS HENDERSON GROUP PLC - JANUS HENDERSON GROUP PLC OWNS >%5 Passive Investment

SC 13G 1 JHBIFAbeona050324.txt JANUS HENDERSON GROUP PLC OWNS >%5 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: ABEONA THERAPEUTICS INC. Title of Class of Securities: Common Stock CUSIP Number: 00289Y206 Date of Event Which Requires Filing of this Statement: 5/3/2024 Check the appropr

May 3, 2024 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 1, 2024 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands 001-38103 98-1376360 (State or other jurisdiction of (Commission F

May 2, 2024 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 2, 2024 Commission File Number 001-38103 JANUS HENDERSON GROUP PLC (Exact name of registrant as specified in its charter) Jersey, Channel Islands (State or other jurisdiction of i

May 2, 2024 EX-99.1

Janus Henderson Group plc Reports First Quarter 2024 Results

Exhibit 99.1 Janus Henderson Group plc Reports First Quarter 2024 Results ● Solid investment performance, with 70%, 60%, 68%, and 85% of assets under management (“AUM”) outperforming relevant benchmarks on a one-, three-, five-, and 10-year basis, respectively, as of March 31, 2024 ● AUM increased 5% quarter over quarter and 14% year over year to US$352.6 billion as of March 31, 2024 ● First quart

May 2, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the transition period from to Commission File Number 001-38103 JAN

April 11, 2024 SC 13G

ABIO / ARCA biopharma, Inc. / JANUS HENDERSON GROUP PLC - JANUS HENDERSON GROUP PLC OWNS 7.4% OF ARCA BIOPHARMA, INC Passive Investment

SC 13G 1 JHBIFArcaBiopharma040324.txt JANUS HENDERSON GROUP PLC OWNS 7.4% OF ARCA BIOPHARMA, INC UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Amendment No.: 0* Name of Issuer: ARCA BIOPHARMA, INC Title of Class of Securities: Common Stock CUSIP Number: 00211Y506 Date of Event Which Requires Filing of this Statement:

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