Dyne Therapeutics, Inc.
US ˙ NasdaqGS ˙ US26818M1080

SecurityDYN / Dyne Therapeutics, Inc.
InstitutionState Street Corp
Latest Disclosed Ownership6,653,746 shares
Latest Disclosed Value $ 120,632,415
State Street Corp reports 0.58% decrease in ownership of DYN / Dyne Therapeutics, Inc.

On May 15, 2026 - State Street Corp filed a 13F-HR form disclosing ownership of 6,653,746 shares of Dyne Therapeutics, Inc. (US:DYN) valued at $120,632,415 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 6,692,745 shares of Dyne Therapeutics, Inc.. This represents a change in shares of -0.58% during the quarter. The current value of the position is $113,379,832 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F DYNE THERAPEUTICS COM 26818M108 6,653,746 -38,999 -0.58 120,632 -7.85 0.0042
2026-02-13 2025-12-31 13F DYNE THERAPEUTICS COM 26818M108 6,692,745 1,423,828 27.02 130,910 96.41 0.0044
2025-11-14 2025-09-30 13F DYNE THERAPEUTICS COM 26818M108 5,268,917 1,913,239 57.01 66,652 108.64 0.0023
2025-08-14 2025-06-30 13F DYNE THERAPEUTICS COM 26818M108 3,355,678 -253,973 -7.04 31,946 -15.39 0.0012
2025-05-15 2025-03-31 13F DYNE THERAPEUTICS COM 26818M108 3,609,651 -107,732 -2.90 37,757 -56.89 0.0016
2025-02-14 2024-12-31 13F DYNE THERAPEUTICS COM 26818M108 3,717,383 75,524 2.07 87,582 -33.05 0.0035
2024-11-14 2024-09-30 13F DYNE THERAPEUTICS COM 26818M108 3,641,859 440,890 13.77 130,816 15.80 0.0053
2024-08-14 2024-06-30 13F DYNE THERAPEUTICS COM 26818M108 3,200,969 -992,584 -23.67 112,962 -5.12 0.0049
2024-05-15 2024-03-31 13F DYNE THERAPEUTICS COM 26818M108 4,193,553 1,856,412 79.43 119,055 283.02 0.0053
2024-02-14 2023-12-31 13F DYNE THERAPEUTICS COM 26818M108 2,337,141 398,499 20.56 31,084 78.95 0.0015
2023-11-14 2023-09-30 13F DYNE THERAPEUTICS COM 26818M108 1,938,642 158,902 8.93 17,370 -13.25 0.0010
2023-08-14 2023-06-30 13F DYNE THERAPEUTICS COM 26818M108 1,779,740 1,178,928 196.22 20,022 189.29 0.0011
2023-05-15 2023-03-31 13F DYNE THERAPEUTICS COM 26818M108 600,812 24,669 4.28 6,921 3.65 0.0004
2023-05-15 2022-12-31 13F/A-99 DYNE THERAPEUTICS COM 26818M108 576,143 -2,737 -0.47 6,677 -9.18 0.0004
2023-05-15 2022-12-31 13F DYNE THERAPEUTICS COM 26818M108 576,143 -2,737 6,677 0.0004
2022-11-15 2022-09-30 13F DYNE THERAPEUTICS COM 26818M108 578,880 19,192 3.43 7,352 91.21 0.0005
2022-08-15 2022-06-30 13F DYNE THERAPEUTICS COM 26818M108 559,688 58,717 11.72 3,845 -20.38 0.0002
2022-05-16 2022-03-31 13F DYNE THERAPEUTICS COM 26818M108 500,971 8,618 1.75 4,829 -17.51 0.0002
2022-02-14 2021-12-31 13F DYNE THERAPEUTICS COM 26818M108 492,353 7,593 1.57 5,854 -25.64 0.0003
2021-11-15 2021-09-30 13F DYNE THERAPEUTICS COM 26818M108 484,760 25,864 5.64 7,873 -18.46 0.0004
2021-08-16 2021-06-30 13F DYNE THERAPEUTICS COM 26818M108 458,896 231,492 101.80 9,655 173.36 0.0005
2021-07-09 2021-03-31 13F/A-1 DYNE THERAPEUTICS COM 26818M108 227,404 5,400 2.43 3,532 -24.24 0.0002
2021-05-17 2021-03-31 13F DYNE THERAPEUTICS COM 26818M108 227,404 5,400 3,532 0.0002
2021-02-16 2020-12-31 13F DYNE THERAPEUTICS COM 26818M108 222,004 222,004 4,662 0.0003
2018-08-14 2018-06-30 13F DYNEGY Conv Bond 26817R405 0 -126,600 -100.00 0 -100.00
2018-05-15 2018-03-31 13F DYNEGY Conv Bond 26817R405 126,600 6,600 5.50 10,937 15.15 0.0009
2018-02-14 2017-12-31 13F DYNEGY Conv Bond 26817R405 120,000 0 0.00 9,498 17.62 0.0008
2017-11-14 2017-09-30 13F DYNEGY Conv Bond 26817R405 120,000 120,000 8,075 0.0007
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.