| Utestående aktier | 7,021,040 shares |
| Insideraktier | 2 313 573 shares |
| Insynsägande | 32,95 % |
| Totalt antal insynspersoner | 36 |
Insider Sentiment Score
Insider sentiment score hittar de företag som köps av foretagsinsynspersoner.
Det är resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av insiderackumulation. Poängmodellen använder en kombination av nettoantalet insiders som köpt de föregående 90 dagarna, det totala antalet aktier som köpts i procent av aktiekapitalet och det totala antalet aktier som ägs av insiders. Siffran sträcker sig från 0 till 100, med högre siffror som indikerar en högre nivå av ackumulering för sina kamrater, och 50 är genomsnittet.
Uppdateringsfrekvens: Dagligen
Se Insiders Top Picks, som ger en lista över företag med högsta insiderackumulation.
Office Sentiment Score
Officersentiment Score hittar företag som köps av Corporate Officers.
Per definition Corporate Officers är Corporate Insiders, men till skillnad från vissa av de andra Insiders (10 % aktieägare och styrelseledamöter), arbetar ämbetsmän för företaget dagligen och de använder sina egna pengar när de handlar . (10 % aktieägare och styrelseledamöter är ofta fondförvaltare som förvaltar andras pengar.) Som sådan är insideraffärer som görs av tjänstemän mycket mer betydelsefulla och bör behandlas på lämpligt sätt.
Liksom Insider Sentiment Score är Officer Sentiment Score resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av officersackumulering.
Uppdateringsfrekvens: Dagligen
Se insiderns bästa val, vilket ger en lista över företag med högsta insider sentiment.
Viktiga insidernyckeltal
Denna kort visar hur företaget rankas längs olika insidernyckeltal. Procenttilrankningen visar hur detta företag jämförs med andra företag på USA-marknaden. Högre rankingar indikerar bättre situationer.
Till exempel anses det allmänt att insiderköp är en positiv indikator, så företag med mer insiderköp skulle rankas högre än företag med mindre insiderköp (eller til och med insiderförsäljning).
Procent av flytande köpta av insiders (ranking)
-0.947 %( )
11032 out of 11219Procentandelen av aktier köpta av insiders är det totala antalet aktier som köpts av insiders minus det totala antalet aktier som sålts av insiders under de senaste 90 dagarna, dividerat med det totala antalet aktier och multiplicerat med 100.
Insiderhandelsdiagram
KALA BIO, Inc. insideraffärer visas i följande diagram. Insiders är tjänstemän, styrelseledamöter eller betydande investerare i ett företag. I allmänhet är det i allmänhet olagligt för insiders att göra affärer i sina företag baserat på väsentlig, icke-offentlig information. Detta betyder inte att det är olagligt för dem att göra några affärer i sina egna företag. De måste dock rapportera alla affärer till SEC via ett formulär 4.
Insiderlista och lönsamhetsstatistik
Den här tabellen visar listan över kända insiders och genereras automatiskt från anmälningar som avslöjas till SEC. Förutom namnen, den senaste titeln och direktören, tjänstemannen eller ägarbeteckningen på 10 %, tillhandahåller vi de senaste avslöjade innehaven. Dessutom, när det är möjligt tillhandahåller vi insiderns historiska handelsresultat. Det historiska handelsresultatet är ett vägt genomsnitt av resultatet för faktiska köptransaktioner på den öppna marknaden som insidern gjort. För mer information om hur detta beräknas, titta på detta YouTube-webinarium.
See our leaderboard of most profitable insider traders.
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
|
Baker Bros. Advisors Lp
10% Owner -
|
1 083 398 | 1 083 398 | |
| Todd Bazemore SEE REMARKS - [O] | 83 699 | 83 699 | |
| Blumenkranz Mark S. Director - [D] | 182 821 | 182 821 | |
| Romulus K Brazzell SEE REMARKS - [O] | 82 698 | 82 698 | |
|
Corp Caxton
10% Owner -
|
763 755 | 15 275 | |
|
Cdk Associates, L.l.c.
10% Owner -
|
763 755 | 15 275 | |
| Hongming Chen CHIEF SCIENTIFIC OFFICER - [O] | 204 515 | 4 090 | |
|
Patrick G Enright
10% Owner -
|
2 270 946 | 45 419 | |
| Marjan Farid Director - [D] | 10 242 | 10 242 | |
| Gregory Grunberg Director - [D] | 40 000 | 800 | |
|
Hadley Harbor Master Investors (Cayman) L.P.
10% Owner -
|
846 566 | 16 931 | |
|
Justin Hanes
10% Owner -
|
1 203 846 | 24 077 |
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
| Paulina Hill | 12 960 | ||
|
Samuel D Isaly
10% Owner -
|
4 904 462 | 98 089 | |
| Mark T Iwicki Director - [D] | 258 433 | 258 433 | |
| Andrew I Koven Director - [D] | 16 972 | 16 972 | |
| Darius Kharabi CHIEF BUSINESS OFFICER - [O] | 62 566 | 62 566 | |
|
Peter Kolchinsky
10% Owner -
|
10 594 767 | 140 792 | |
|
Bruce Kovner
10% Owner -
|
763 755 | 15 275 | |
|
Robert Langer
Director, 10% Owner -
[D]
|
652 804 | 13 056 | |
| Michele LaRussa | 8 000 | ||
|
Longitude Capital Partners II, LLC
10% Owner -
|
2 270 946 | 45 419 | |
|
Longitude Venture Partners II, L.P.
10% Owner -
|
2 270 946 | 45 419 | |
| Myers C. Daniel Director - [D] | 10 374 | 10 374 |
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
|
Orbimed Advisors Llc
10% Owner -
|
3 447 840 | 68 957 | |
|
OrbiMed Capital GP VI LLC
10% Owner -
|
3 447 840 | 68 957 | |
| Gregory D Perry Director - [D] | 13 344 | 13 344 | |
| Robert Bradley Paull Director - [D] | 40 000 | 800 | |
|
Ra Capital Management, Llc
10% Owner -
|
7 039 613 | 140 792 | |
|
RA Capital Healthcare Fund LP
10% Owner -
|
10 594 767 | 140 792 | |
| Mary Reumuth CHIEF FINANCIAL OFFICER - [O] | 62 100 | 62 100 | |
| Howard B Rosen Director - [D] | 16 240 | 16 240 | |
|
Shah Rajeev M.
10% Owner -
|
7 039 613 | 140 792 | |
| Robert I Tepper Director - [D] | 1 621 092 | 32 422 | |
|
Bakker Juliet Tammenoms
10% Owner -
|
2 270 946 | 45 419 | |
| Eric Trachtenberg SEE REMARKS - [O] | 68 066 | 68 066 |
Report errors via our new Insider Auditing Tool
Track Records av insiderköp - Kortsiktig vinstanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i KALA / KALA BIO, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste köpen på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Track Records av insiderförsäljning - Kortsiktig förlustanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i KALA / KALA BIO, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste försäljningarna på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Transaktionshistorik
Klicka på länkikonen för att se hela transaktionshistoriken. Transaktioner som rapporteras som en del av en automatisk handelsplan 10b5-1 kommer att ha ett X i kolumnen markerad 10b-5.
| Fil datum |
Handel datum |
Schema | Insider | Ticker | Värdepappertitel | Kod | Direkta | Utövningspris | Enhet pris |
Enheter ändrad |
Värde ändrad (1K) |
Kvarvarande Optioner |
Kvarvarande Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-06-26 | 2025-06-24 | 4 | Kharabi Darius | KALA | Common Stock | D | 4,0100 | −4 511 | −18 | 62 566 | ||||
| 2025-06-26 | 2025-06-24 | 4 | Iwicki Mark T | KALA | Common Stock | D | 4,0100 | −13 227 | −53 | 258 433 | ||||
| 2025-06-26 | 2025-06-24 | 4 | Bazemore Todd | KALA | Common Stock | D | 4,0100 | −4 058 | −16 | 83 699 | ||||
| 2025-06-26 | 2025-06-24 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 4,0100 | −5 251 | −21 | 82 698 | ||||
| 2025-06-26 | 2025-06-24 | 4 | Reumuth Mary | KALA | Common Stock | D | 4,0100 | −3 631 | −15 | 62 100 | ||||
| 2025-06-17 | 2025-06-15 | 4 | Rosen Howard B | KALA | Common Stock | D | 2 450 | 16 240 | ||||||
| 2025-06-17 | 2025-06-15 | 4 | KOVEN ANDREW I | KALA | Common Stock | D | 3 050 | 16 972 | ||||||
| 2025-06-17 | 2025-06-15 | 4 | Myers C. Daniel | KALA | Common Stock | D | 2 450 | 10 374 | ||||||
| 2025-06-17 | 2025-06-15 | 4 | PERRY GREGORY D | KALA | Common Stock | D | 2 450 | 13 344 | ||||||
| 2025-06-17 | 2025-06-15 | 4 | Farid Marjan | KALA | Common Stock | D | 2 450 | 10 242 | ||||||
| 2025-06-17 | 2025-06-15 | 4 | Iwicki Mark T | KALA | Common Stock | D | 2 450 | 271 660 | ||||||
| 2025-06-05 | 2025-06-03 | 4/A | Iwicki Mark T | KALA | Common Stock | D | 3,7400 | −10 866 | −41 | 269 210 | ||||
| 2025-06-04 | 2025-06-03 | 4 | Iwicki Mark T | KALA | Common Stock | D | 3,7400 | 10 866 | 41 | 269 210 | ||||
| 2025-06-04 | 2025-06-03 | 4 | Bazemore Todd | KALA | Common Stock | D | 3,7400 | −3 390 | −13 | 87 757 | ||||
| 2025-06-04 | 2025-06-03 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 3,7400 | −3 687 | −14 | 87 949 | ||||
| 2025-06-04 | 2025-06-03 | 4 | Reumuth Mary | KALA | Common Stock | D | 3,7400 | −2 850 | −11 | 65 731 | ||||
| 2025-06-04 | 2025-06-03 | 4 | Kharabi Darius | KALA | Common Stock | D | 3,7400 | −730 | −3 | 67 077 | ||||
| 2025-01-07 | 2025-01-06 | 4 | Bazemore Todd | KALA | Common Stock | D | 7,6300 | −1 993 | −15 | |||||
| 2025-01-07 | 2025-01-06 | 4 | Bazemore Todd | KALA | Common Stock | D | 10 100 | |||||||
| 2025-01-07 | 2025-01-06 | 4 | Kharabi Darius | KALA | Common Stock | D | 7,6300 | −2 021 | −15 | 67 807 | ||||
| 2025-01-07 | 2025-01-06 | 4 | Kharabi Darius | KALA | Common Stock | D | 10 100 | 69 828 | ||||||
| 2025-01-07 | 2025-01-06 | 4 | Iwicki Mark T | KALA | Common Stock | D | 7,6300 | −5 779 | −44 | 280 076 | ||||
| 2025-01-07 | 2025-01-06 | 4 | Iwicki Mark T | KALA | Common Stock | D | 22 100 | 285 855 | ||||||
| 2025-01-07 | 2025-01-06 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 7,6300 | −2 446 | −19 | 92 418 | ||||
| 2025-01-07 | 2025-01-06 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 10 100 | 94 864 | ||||||
| 2025-01-07 | 2025-01-06 | 4 | Reumuth Mary | KALA | Common Stock | D | 7,6300 | −1 706 | −13 | 68 581 | ||||
| 2025-01-07 | 2025-01-06 | 4 | Reumuth Mary | KALA | Common Stock | D | 10 100 | 70 287 | ||||||
| 2024-12-31 | 2024-12-30 | 4 | BAKER BROS. ADVISORS LP See Footnotes | KALA | Common Stock | I | 6,4400 | 279 939 | 1 803 | 1 083 398 | ||||
| 2024-12-31 | 2024-12-30 | 4 | BAKER BROS. ADVISORS LP See Footnotes | KALA | Common Stock | I | 6,4400 | 30 620 | 197 | 118 496 | ||||
| 2024-06-28 | 3 | BAKER BROS. ADVISORS LP See Footnotes | KALA | Common Stock | I | 87 876 | ||||||||
| 2024-06-28 | 3 | BAKER BROS. ADVISORS LP See Footnotes | KALA | Common Stock | I | 803 459 | ||||||||
| 2024-06-27 | 2024-06-26 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 4,7500 | −5 489 | −26 | 83 982 | ||||
| 2024-06-27 | 2024-06-26 | 4 | Reumuth Mary | KALA | Common Stock | D | 4,7500 | −4 163 | −20 | 60 187 | ||||
| 2024-06-27 | 2024-06-26 | 4 | Iwicki Mark T | KALA | Common Stock | D | 4,7500 | −15 168 | −72 | 263 755 | ||||
| 2024-06-27 | 2024-06-26 | 4 | Kharabi Darius | KALA | Common Stock | D | 4,7500 | −5 158 | −25 | 59 728 | ||||
| 2024-06-27 | 2024-06-26 | 4 | Bazemore Todd | KALA | Common Stock | D | 4,7500 | −4 653 | −22 | 83 040 | ||||
| 2024-06-12 | 2024-06-11 | 4 | Blumenkranz Mark S. | KALA | Common Stock | D | 1 400 | 13 091 | ||||||
| 2024-06-12 | 2024-06-11 | 4 | KOVEN ANDREW I | KALA | Common Stock | D | 1 750 | 13 922 | ||||||
| 2024-06-12 | 2024-06-11 | 4 | Myers C. Daniel | KALA | Common Stock | D | 1 400 | 7 924 | ||||||
| 2024-06-12 | 2024-06-11 | 4 | PERRY GREGORY D | KALA | Common Stock | D | 1 400 | 10 894 | ||||||
| 2024-06-12 | 2024-06-11 | 4 | Rosen Howard B | KALA | Common Stock | D | 1 400 | 13 887 | ||||||
| 2024-06-12 | 2024-06-11 | 4 | Farid Marjan | KALA | Common Stock | D | 1 400 | 7 792 | ||||||
| 2024-06-03 | 2024-05-31 | 4 | Iwicki Mark T | KALA | Common Stock | D | 6,0900 | −7 392 | −45 | 278 923 | ||||
| 2024-06-03 | 2024-05-31 | 4 | Reumuth Mary | KALA | Common Stock | D | 6,0900 | −1 786 | −11 | 64 350 | ||||
| 2024-06-03 | 2024-05-31 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 6,0900 | −2 002 | −12 | 89 471 | ||||
| 2024-06-03 | 2024-05-31 | 4 | Kharabi Darius | KALA | Common Stock | D | 6,0900 | −231 | −1 | 64 886 | ||||
| 2024-06-03 | 2024-05-31 | 4 | Bazemore Todd | KALA | Common Stock | D | 6,0900 | −2 093 | −13 | 87 693 | ||||
| 2024-01-05 | 2024-01-04 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 6,7400 | −1 227 | −8 | 68 066 | ||||
| 2024-01-05 | 2024-01-04 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 4 600 | 69 293 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 6,7400 | −1 617 | −11 | 91 473 | ||||
| 2024-01-05 | 2024-01-04 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 6 500 | 93 090 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Kharabi Darius | KALA | Common Stock | D | 6,7300 | −1 385 | −9 | 65 117 | ||||
| 2024-01-05 | 2024-01-04 | 4 | Kharabi Darius | KALA | Common Stock | D | 4 600 | 66 502 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Reumuth Mary | KALA | Common Stock | D | 6,7400 | −1 227 | −8 | 66 136 | ||||
| 2024-01-05 | 2024-01-04 | 4 | Reumuth Mary | KALA | Common Stock | D | 4 600 | 67 363 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Iwicki Mark T | KALA | Common Stock | D | 6,7300 | −4 539 | −31 | 286 315 | ||||
| 2024-01-05 | 2024-01-04 | 4 | Iwicki Mark T | KALA | Common Stock | D | 14 300 | 290 854 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Bazemore Todd | KALA | Common Stock | D | 6,7400 | −1 405 | −9 | |||||
| 2024-01-05 | 2024-01-04 | 4 | Bazemore Todd | KALA | Common Stock | D | 6 500 | |||||||
| 2023-06-23 | 2023-06-22 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 37 559 | 64 693 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Blumenkranz Mark S. | KALA | Common Stock | D | 1 100 | 11 691 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Blumenkranz Mark S. | KALA | Common Stock | D | 3 784 | 10 591 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Rosen Howard B | KALA | Common Stock | D | 1 100 | 12 487 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Rosen Howard B | KALA | Common Stock | D | 7 988 | 11 387 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 49 356 | 85 808 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | KOVEN ANDREW I | KALA | Common Stock | D | 1 400 | 12 172 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | KOVEN ANDREW I | KALA | Common Stock | D | 7 515 | 10 772 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Reumuth Mary | KALA | Common Stock | D | 36 144 | 62 763 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Myers C. Daniel | KALA | Common Stock | D | 1 100 | 6 524 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Myers C. Daniel | KALA | Common Stock | D | 3 784 | 5 424 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Iwicki Mark T | KALA | Common Stock | D | 158 873 | 276 554 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | PERRY GREGORY D | KALA | Common Stock | D | 1 100 | 9 494 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | PERRY GREGORY D | KALA | Common Stock | D | 5 856 | 8 394 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Bazemore Todd | KALA | Common Stock | D | 48 698 | 84 691 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Kharabi Darius | KALA | Common Stock | D | 36 847 | 61 902 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Farid Marjan | KALA | Common Stock | D | 1 100 | 6 392 | ||||||
| 2023-06-23 | 2023-06-22 | 4 | Farid Marjan | KALA | Common Stock | D | 3 692 | 5 292 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | Myers C. Daniel | KALA | Common Stock | D | 1 640 | 1 640 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | PERRY GREGORY D | KALA | Common Stock | D | 1 738 | 2 538 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | Iwicki Mark T | KALA | Common Stock | D | 71 715 | 117 681 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | Farid Marjan | KALA | Common Stock | D | 1 600 | 1 600 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | Bazemore Todd | KALA | Common Stock | D | 21 158 | 35 993 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | Blumenkranz Mark S. | KALA | Common Stock | D | 1 640 | 6 807 | ||||||
| 2023-06-02 | 2023-03-10 | 4 | Blumenkranz Mark S. | KALA | Common Stock | I | 497 | 1 276 | ||||||
| 2023-06-02 | 2023-03-10 | 4 | Blumenkranz Mark S. | KALA | Common Stock | I | 65 634 | 168 454 | ||||||
| 2023-06-02 | 2023-03-10 | 4 | Blumenkranz Mark S. | KALA | Common Stock | D | 2 013 | 5 167 | ||||||
| 2023-06-02 | 2023-02-15 | 4 | Blumenkranz Mark S. | KALA | Common Stock | I | −2 | 779 | ||||||
| 2023-06-02 | 2023-02-15 | 4 | Blumenkranz Mark S. | KALA | Common Stock | I | −68 | 102 820 | ||||||
| 2023-06-02 | 2023-02-15 | 4 | Blumenkranz Mark S. | KALA | Common Stock | D | −3 | 3 154 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | KOVEN ANDREW I | KALA | Common Stock | D | 2 197 | 3 257 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 17 916 | 36 452 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | Rosen Howard B | KALA | Common Stock | D | 2 502 | 3 399 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 15 639 | 27 134 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | Reumuth Mary | KALA | Common Stock | D | 14 736 | 26 619 | ||||||
| 2023-06-02 | 2023-05-31 | 4 | Kharabi Darius | KALA | Common Stock | D | 2 648 | 25 055 | ||||||
| 2023-06-02 | 2023-03-10 | 4 | Kharabi Darius | KALA | Common Stock | D | 6 977 | 22 407 | ||||||
| 2023-06-02 | 2022-02-15 | 4 | Kharabi Darius | KALA | Common Stock | D | −9 | 15 430 | ||||||
| 2023-01-06 | 2023-01-04 | 4 | Iwicki Mark T | KALA | Common Stock | D | 28,5400 | −198 | −6 | 45 966 | ||||
| 2023-01-06 | 2023-01-04 | 4 | Iwicki Mark T | KALA | Common Stock | D | 41 700 | 46 164 | ||||||
| 2023-01-06 | 2023-01-04 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 28,5300 | −73 | −2 | 18 536 | ||||
| 2023-01-06 | 2023-01-04 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 12 800 | 18 609 | ||||||
| 2023-01-06 | 2023-01-04 | 4 | Bazemore Todd | KALA | Common Stock | D | 28,5400 | −62 | −2 | 14 835 | ||||
| 2023-01-06 | 2023-01-04 | 4 | Bazemore Todd | KALA | Common Stock | D | 12 800 | 14 897 | ||||||
| 2023-01-06 | 2023-01-04 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 28,5500 | −60 | −2 | 11 495 | ||||
| 2023-01-06 | 2023-01-04 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 9 525 | 11 555 | ||||||
| 2023-01-06 | 2023-01-04 | 4 | Reumuth Mary | KALA | Common Stock | D | 28,5400 | −60 | −2 | 11 883 | ||||
| 2023-01-06 | 2023-01-04 | 4 | Reumuth Mary | KALA | Common Stock | D | 9 525 | 11 943 | ||||||
| 2023-01-06 | 2023-01-04 | 4 | Kharabi Darius | KALA | Common Stock | D | 9 525 | 15 439 | ||||||
| 2022-10-28 | 2022-10-26 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 6,5200 | −194 | −1 | 2 030 | ||||
| 2022-10-28 | 2022-10-26 | 4 | Iwicki Mark T | KALA | Common Stock | D | 6,5200 | −561 | −4 | 4 464 | ||||
| 2022-10-28 | 2022-10-26 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 6,5100 | −261 | −2 | 5 809 | ||||
| 2022-10-28 | 2022-10-26 | 4 | Reumuth Mary | KALA | Common Stock | D | 6,5100 | −194 | −1 | 2 418 | ||||
| 2022-10-28 | 2022-10-26 | 4 | Bazemore Todd | KALA | Common Stock | D | 6,5100 | −214 | −1 | 2 097 | ||||
| 2022-06-29 | 2022-06-27 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 0,3700 | −2 613 | −1 | 111 203 | ||||
| 2022-06-29 | 2022-06-27 | 4 | Reumuth Mary | KALA | Common Stock | D | 0,3700 | −2 613 | −1 | 130 595 | ||||
| 2022-06-29 | 2022-06-27 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 0,3700 | −3 144 | −1 | 285 201 | ||||
| 2022-06-29 | 2022-06-27 | 4 | Bazemore Todd | KALA | Common Stock | D | 0,3700 | −3 092 | −1 | 115 499 | ||||
| 2022-06-29 | 2022-06-27 | 4 | Iwicki Mark T | KALA | Common Stock | D | 0,3700 | −7 975 | −3 | 251 183 | ||||
| 2022-05-26 | 2022-05-26 | 4 | RA CAPITAL MANAGEMENT, LLC See Footnotes | KALA | Common Stock | I | 0,3636 | −1 005 686 | −366 | 7 039 613 | ||||
| 2022-05-25 | 2022-05-25 | 4 | RA CAPITAL MANAGEMENT, LLC See Footnotes | KALA | Common Stock | I | 0,4200 | −1 434 509 | −602 | 8 045 299 | ||||
| 2022-05-25 | 2022-05-24 | 4 | RA CAPITAL MANAGEMENT, LLC See Footnotes | KALA | Common Stock | I | 0,5100 | −144 805 | −74 | 9 479 808 | ||||
| 2022-05-25 | 2022-05-23 | 4 | RA CAPITAL MANAGEMENT, LLC See Footnotes | KALA | Common Stock | I | 0,6500 | −1 250 000 | −812 | 9 624 613 | ||||
| 2022-01-05 | 2022-01-04 | 4 | Iwicki Mark T | KALA | Common Stock | D | 1,3000 | −9 518 | −12 | 259 158 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Iwicki Mark T | KALA | Stock Option (right to buy) | D | 1,37 | 775 000 | 775 000 | |||||
| 2022-01-05 | 2022-01-04 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 1,3000 | −3 504 | −5 | 288 345 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 1,37 | 238 000 | 238 000 | |||||
| 2022-01-05 | 2022-01-04 | 4 | Reumuth Mary | KALA | Common Stock | D | 1,3000 | −2 850 | −4 | 133 208 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Reumuth Mary | KALA | Stock Option (right to buy) | D | 1,37 | 153 000 | 153 000 | |||||
| 2022-01-05 | 2022-01-04 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 1,3000 | −2 850 | −4 | 113 816 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Trachtenberg Eric | KALA | Stock Option (right to buy) | D | 1,37 | 153 000 | 153 000 | |||||
| 2022-01-05 | 2022-01-04 | 4 | Bazemore Todd | KALA | Common Stock | D | 1,3000 | −3 454 | −4 | 118 591 | ||||
| 2022-01-05 | 2022-01-03 | 4 | Bazemore Todd | KALA | Stock Option (right to buy) | D | 1,37 | 238 000 | 238 000 | |||||
| 2021-11-17 | 2021-11-15 | 4 | Kharabi Darius | KALA | Stock Option (right to buy) | D | 2,10 | 100 000 | 100 000 | |||||
| 2021-11-17 | 2021-11-15 | 4 | Kharabi Darius | KALA | Common Stock | D | 295 657 | 295 657 | ||||||
| 2021-11-17 | 2021-11-15 | 4 | Blumenkranz Mark S. | KALA | Stock Option (right to buy) | D | 2,10 | 42 000 | 42 000 | |||||
| 2021-11-17 | 2021-11-15 | 4 | Blumenkranz Mark S. | KALA | Common Stock | I | 38 965 | 38 965 | ||||||
| 2021-11-17 | 2021-11-15 | 4 | Blumenkranz Mark S. | KALA | Common Stock | I | 5 144 390 | 5 144 390 | ||||||
| 2021-11-17 | 2021-11-15 | 4 | Blumenkranz Mark S. | KALA | Common Stock | D | 157 765 | 157 765 | ||||||
| 2021-10-28 | 2021-10-27 | 4 | Chen Hongming | KALA | Common Stock | D | 1,8200 | −21 051 | −38 | 204 515 | ||||
| 2021-10-28 | 2021-10-26 | 4 | Chen Hongming | KALA | Common Stock | D | 1,8000 | −9 449 | −17 | 225 566 | ||||
| 2021-10-28 | 2021-10-26 | 4 | Reumuth Mary | KALA | Common Stock | D | 1,8000 | −9 449 | −17 | 136 058 | ||||
| 2021-10-28 | 2021-10-26 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 1,8000 | −9 449 | −17 | 116 666 | ||||
| 2021-10-28 | 2021-10-26 | 4 | Bazemore Todd | KALA | Common Stock | D | 1,8000 | −12 544 | −23 | 122 045 | ||||
| 2021-10-28 | 2021-10-26 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 1,8000 | −12 757 | −23 | 291 849 | ||||
| 2021-10-28 | 2021-10-26 | 4 | Iwicki Mark T | KALA | Common Stock | D | 1,8000 | −27 598 | −50 | 268 676 | ||||
| 2021-10-19 | 2021-10-15 | 4 | Myers C. Daniel | KALA | Stock Option (right to buy) | D | 2,21 | 42 000 | 42 000 | |||||
| 2021-06-30 | 2021-06-29 | 4 | Chen Hongming | KALA | Common Stock | D | 5,5600 | −5 548 | −31 | 235 015 | ||||
| 2021-06-29 | 2021-06-28 | 4 | Chen Hongming | KALA | Common Stock | D | 5,7700 | −2 452 | −14 | 240 563 | ||||
| 2021-06-29 | 2021-06-28 | 4 | Bazemore Todd | KALA | Common Stock | D | 5,7700 | −2 911 | −17 | |||||
| 2021-06-29 | 2021-06-28 | 4 | Iwicki Mark T | KALA | Common Stock | D | 5,7700 | −7 586 | −44 | 296 274 | ||||
| 2021-06-29 | 2021-06-28 | 4 | Reumuth Mary | KALA | Common Stock | D | 5,7700 | −2 452 | −14 | 145 507 | ||||
| 2021-06-29 | 2021-06-28 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 5,7700 | −2 452 | −14 | 126 115 | ||||
| 2021-06-29 | 2021-06-28 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 5,7700 | −3 034 | −18 | 300 962 | ||||
| 2021-06-21 | 2021-06-17 | 4 | Shah Rajeev M. | KALA | Common Stock | D | 20 000 | 20 000 | ||||||
| 2021-06-21 | 2021-06-17 | 4 | Rosen Howard B | KALA | Common Stock | D | 20 000 | 44 824 | ||||||
| 2021-06-21 | 2021-06-17 | 4 | Grunberg Gregory | KALA | Common Stock | D | 20 000 | 40 000 | ||||||
| 2021-06-21 | 2021-06-17 | 4 | KOVEN ANDREW I | KALA | Common Stock | D | 25 000 | 53 000 | ||||||
| 2021-06-21 | 2021-06-17 | 4 | Paull Robert Bradley | KALA | Common Stock | D | 20 000 | 40 000 | ||||||
| 2021-06-21 | 2021-06-17 | 4 | PERRY GREGORY D | KALA | Common Stock | D | 20 000 | 40 000 | ||||||
| 2021-04-05 | 2021-04-01 | 4 | RA CAPITAL MANAGEMENT, LLC | KALA | Common Stock | I | 6,7400 | 1 407 863 | 9 489 | 10 594 767 | ||||
| 2021-04-05 | 2021-04-01 | 4 | RA CAPITAL MANAGEMENT, LLC | KALA | Common Stock | I | 6,7400 | 279 846 | 1 886 | 279 846 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Chen Hongming | KALA | Stock Option (right to buy | D | 2,30 | −9 500 | 53 736 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Chen Hongming | KALA | Common Stock | D | 2,3000 | 9 500 | 22 | 243 015 | ||||
| 2021-02-26 | 2021-02-25 | 4 | Chen Hongming | KALA | Stock Option (right to buy) | D | 2,30 | −47 000 | 63 236 | |||||
| 2021-02-26 | 2021-02-25 | 4 | Chen Hongming | KALA | Common Stock | D | 2,3000 | 47 000 | 108 | 233 515 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 6,86 | 110 000 | 110 000 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 27 500 | 303 996 | ||||||
| 2021-01-05 | 2021-01-04 | 4 | Chen Hongming | KALA | Stock Option (right to buy) | D | 6,86 | 90 667 | 90 667 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Chen Hongming | KALA | Common Stock | D | 22 666 | 186 515 | ||||||
| 2021-01-05 | 2021-01-04 | 4 | Trachtenberg Eric | KALA | Stock Option (right to buy) | D | 6,86 | 90 667 | 90 667 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 22 666 | 128 567 | ||||||
| 2021-01-05 | 2021-01-04 | 4 | Bazemore Todd | KALA | Stock Option (right to buy) | D | 6,86 | 110 000 | 110 000 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Bazemore Todd | KALA | Common Stock | D | 27 500 | 137 500 | ||||||
| 2021-01-05 | 2021-01-04 | 4 | Iwicki Mark T | KALA | Stock Option (right to buy) | D | 6,86 | 303 000 | 303 000 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Iwicki Mark T | KALA | Common Stock | D | 76 000 | 303 860 | ||||||
| 2021-01-05 | 2021-01-04 | 4 | Reumuth Mary | KALA | Stock Option (right to buy) | D | 6,86 | 90 667 | 90 667 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Reumuth Mary | KALA | Common Stock | D | 22 666 | 147 959 | ||||||
| 2020-10-28 | 2020-10-26 | 4 | Bazemore Todd | KALA | Common Stock | D | 81 000 | 110 000 | ||||||
| 2020-10-28 | 2020-10-22 | 4 | Bazemore Todd By son | KALA | Common Stock | I | 7,6000 | 40 | 0 | 42 | ||||
| 2020-10-28 | 2020-06-05 | 4 | Bazemore Todd By son | KALA | Common Stock | I | 13,3900 | 2 | 0 | 2 | ||||
| 2020-10-28 | 2020-10-26 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 61 000 | 105 901 | ||||||
| 2020-10-28 | 2020-10-26 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 81 000 | 276 496 | ||||||
| 2020-10-28 | 2020-10-26 | 4 | Chen Hongming | KALA | Common Stock | D | 61 000 | 163 849 | ||||||
| 2020-10-28 | 2020-10-26 | 4 | Reumuth Mary | KALA | Common Stock | D | 61 000 | 125 293 | ||||||
| 2020-10-28 | 2020-10-26 | 4 | Iwicki Mark T | KALA | Common Stock | D | 178 300 | 227 860 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | Iwicki Mark T | KALA | Common Stock | D | 49 560 | 49 560 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | Rosen Howard B | KALA | Common Stock | D | 20 000 | 24 824 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | Shah Rajeev M. | KALA | Common Stock | D | 20 000 | 20 000 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | Paull Robert Bradley | KALA | Common Stock | D | 20 000 | 20 000 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | PERRY GREGORY D | KALA | Common Stock | D | 20 000 | 20 000 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | Reumuth Mary | KALA | Common Stock | D | 16 000 | 64 293 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | Bazemore Todd | KALA | Common Stock | D | 19 000 | 29 000 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | Chen Hongming | KALA | Comman Stock | D | 16 000 | 102 849 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | KOVEN ANDREW I | KALA | Common Stock | D | 28 000 | 28 000 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 19 000 | 195 496 | ||||||
| 2020-06-29 | 2020-06-25 | 4 | Grunberg Gregory | KALA | Common Stock | D | 20 000 | 5 431 860 | ||||||
| 2020-06-29 | 2020-03-11 | 4 | Paull Robert Bradley | KALA | Common Stock | I | 1 287 | 2 361 | ||||||
| 2020-06-29 | 2018-06-11 | 4 | Paull Robert Bradley | KALA | Common Stock | I | 477 | 1 074 | ||||||
| 2020-06-29 | 2018-05-18 | 4 | Paull Robert Bradley | KALA | Common Stock | I | 597 | 597 | ||||||
| 2020-06-29 | 2019-08-19 | 4 | Rosen Howard B | KALA | Common Stock | D | 0,4700 | 1 944 | 1 | 13 064 | ||||
| 2020-06-29 | 2019-08-19 | 4 | Rosen Howard B | KALA | Common Stock | D | 0,6800 | 2 880 | 2 | 11 120 | ||||
| 2020-06-29 | 2020-06-25 | 4 | Trachtenberg Eric | KALA | Comman Stock | D | 16 000 | 44 901 | ||||||
| 2020-06-22 | 2020-06-19 | 4 | Trachtenberg Eric | KALA | Stock Option (right to buy) | D | 5,19 | −28 901 | 136 099 | |||||
| 2020-06-22 | 2020-06-19 | 4 | Trachtenberg Eric | KALA | Common Stock | D | 5,1900 | 28 901 | 150 | 28 901 | ||||
| 2020-06-11 | 2020-06-09 | 4 | Reumuth Mary | KALA | Stock Option (right to buy) | D | 2,30 | −11 520 | 0 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Reumuth Mary | KALA | Stock Option (right to buy) | D | 2,30 | −11 520 | 0 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Reumuth Mary | KALA | Stock Option (right to buy) | D | 2,30 | −15 360 | 0 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Reumuth Mary | KALA | Stock Option (right to buy) | D | 5,21 | −5 077 | 0 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Reumuth Mary | KALA | Common Stock | D | 2,3000 | 11 520 | 26 | 48 293 | ||||
| 2020-06-11 | 2020-06-09 | 4 | Reumuth Mary | KALA | Common Stock | D | 2,3000 | 11 520 | 26 | 48 293 | ||||
| 2020-06-11 | 2020-06-09 | 4 | Reumuth Mary | KALA | Common Stock | D | 2,3000 | 15 360 | 35 | 36 773 | ||||
| 2020-06-11 | 2020-06-09 | 4 | Reumuth Mary | KALA | Common Stock | D | 5,2100 | 5 077 | 26 | 21 413 | ||||
| 2020-04-13 | 2020-04-09 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 3,34 | −47 644 | 13 508 | |||||
| 2020-04-13 | 2020-04-09 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 2,30 | −18 247 | 0 | |||||
| 2020-04-13 | 2020-04-09 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 0,68 | −1 880 | 0 | |||||
| 2020-04-13 | 2020-04-09 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 3,3400 | 47 644 | 159 | 176 496 | ||||
| 2020-04-13 | 2020-04-09 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 2,3000 | 18 247 | 42 | 128 852 | ||||
| 2020-04-13 | 2020-04-09 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 0,6800 | 1 880 | 1 | 110 605 | ||||
| 2020-04-01 | 2020-03-30 | 4 | Chen Hongming | KALA | Stock Option (right to buy) | D | 2,30 | −31 000 | 75 236 | |||||
| 2020-04-01 | 2020-03-30 | 4 | Chen Hongming | KALA | Common Stock | D | 2,3000 | 31 000 | 71 | 86 849 | ||||
| 2020-03-17 | 2020-03-16 | 4 | Bazemore Todd | KALA | Common Stock | D | 5,7500 | 10 000 | 58 | 10 000 | ||||
| 2020-03-16 | 2020-03-13 | 4 | Grunberg Gregory By Longitude Venture Partners IV, L.P. | KALA | Common Stock | I | 7,8900 | 2 534 854 | 20 000 | 2 534 854 | ||||
| 2020-03-13 | 2020-03-13 | 4 | RA CAPITAL MANAGEMENT, LLC See footnotes | KALA | Common Stock | I | 7,8900 | 6 337 135 | 50 000 | 10 874 613 | ||||
| 2020-03-13 | 2020-03-13 | 4 | Shah Rajeev M. See footnotes | KALA | Common Stock | I | 7,8900 | 6 337 135 | 50 000 | 10 874 613 | ||||
| 2020-01-03 | 2020-01-02 | 4 | Reumuth Mary | KALA | Stock Option (right to buy) | D | 3,84 | 120 000 | 120 000 | |||||
| 2020-01-03 | 2020-01-02 | 4 | Chen Hongming | KALA | Stock Option (right to buy) | D | 3,84 | 120 000 | 120 000 | |||||
| 2020-01-03 | 2020-01-02 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 3,84 | 120 000 | 120 000 | |||||
| 2020-01-03 | 2020-01-02 | 4 | Bazemore Todd | KALA | Stock Option (right to buy) | D | 3,84 | 120 000 | 120 000 | |||||
| 2020-01-03 | 2020-01-02 | 4 | Iwicki Mark T | KALA | Stock Option (right to buy) | D | 3,84 | 365 000 | 365 000 | |||||
| 2020-01-03 | 2020-01-02 | 4 | Trachtenberg Eric | KALA | Stock Option (right to buy) | D | 3,84 | 120 000 | 120 000 | |||||
| 2019-10-15 | 2019-10-12 | 4 | Trachtenberg Eric | KALA | Stock Option (right to buy) | D | 3,45 | 100 000 | 100 000 | |||||
| 2019-10-15 | 2019-10-12 | 4 | Bazemore Todd | KALA | Stock Option (right to buy) | D | 3,45 | 175 000 | 175 000 | |||||
| 2019-06-07 | 2019-06-05 | 4 | Rosen Howard B | KALA | Stock Option (right to buy) | D | 5,35 | 21 000 | 21 000 | |||||
| 2019-06-07 | 2019-06-05 | 4 | Shah Rajeev M. | KALA | Stock Option (right to buy) | D | 5,35 | 21 000 | 21 000 | |||||
| 2019-06-07 | 2019-06-05 | 4 | KOVEN ANDREW I | KALA | Stock Option (right to buy) | D | 5,35 | 21 000 | 21 000 | |||||
| 2019-06-07 | 2019-06-05 | 4 | Grunberg Gregory | KALA | Stock Option (right to buy) | D | 5,35 | 21 000 | 21 000 | |||||
| 2019-06-07 | 2019-06-05 | 4 | Paull Robert Bradley | KALA | Stock Option (right to buy) | D | 5,35 | 21 000 | 21 000 | |||||
| 2019-06-07 | 2019-06-05 | 4 | PERRY GREGORY D | KALA | Stock Option (right to buy) | D | 5,35 | 21 000 | 21 000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Rosen Howard B | KALA | Common stock | D | 5,4200 | 5 000 | 27 | 8 240 | ||||
| 2019-01-04 | 2019-01-02 | 4 | Reumuth Mary | KALA | Stock Option (right to buy) | D | 5,19 | 150 000 | 150 000 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Trachtenberg Eric | KALA | Stock Option (right to buy) | D | 5,19 | 165 000 | 165 000 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Chen Hongming | KALA | Stock Option (right to buy) | D | 5,19 | 150 000 | 150 000 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Bazemore Todd | KALA | Stock Option (right to buy) | D | 5,19 | 175 000 | 175 000 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 5,19 | 150 000 | 150 000 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Iwicki Mark T | KALA | Stock Option (right to buy) | D | 5,19 | 460 000 | 460 000 | |||||
| 2018-10-09 | 2018-10-05 | 4 | Grunberg Gregory By Longitude Venture Partners II, L.P. | KALA | Common Stock | I | 8,2500 | 606 060 | 5 000 | 2 877 006 | ||||
| 2018-10-05 | 2018-10-03 | 4 | RA CAPITAL MANAGEMENT, LLC See footnotes | KALA | Common Stock | I | 8,2500 | 2 424 242 | 20 000 | 4 537 478 | ||||
| 2018-10-05 | 2018-10-03 | 4 | Shah Rajeev M. See footnotes | KALA | Common Stock | I | 8,2500 | 2 424 242 | 20 000 | 4 537 478 | ||||
| 2018-06-15 | 2018-06-12 | 4 | LANGER ROBERT | KALA | Stock Option (right to buy) | D | 13,73 | 12 960 | 12 960 | |||||
| 2018-06-15 | 2018-06-12 | 4 | Shah Rajeev M. | KALA | Stock Option (right to buy) | D | 13,73 | 12 960 | 12 960 | |||||
| 2018-06-14 | 2018-06-12 | 4 | Rosen Howard B | KALA | Stock Option (right to buy) | D | 13,73 | 12 960 | 12 960 | |||||
| 2018-06-14 | 2018-06-12 | 4 | Paull Robert Bradley | KALA | Stock Option (right to buy) | D | 13,73 | 12 960 | 12 960 | |||||
| 2018-06-14 | 2018-06-12 | 4 | Hill Paulina | KALA | Stock Option (right to buy) | D | 13,73 | 12 960 | 12 960 | |||||
| 2018-06-14 | 2018-06-12 | 4 | Grunberg Gregory | KALA | Stock Option (right to buy) | D | 13,73 | 12 960 | 12 960 | |||||
| 2018-06-14 | 2018-06-12 | 4 | KOVEN ANDREW I | KALA | Stock Option (right to buy) | D | 13,73 | 12 960 | 12 960 | |||||
| 2018-04-09 | 2018-04-05 | 4 | Trachtenberg Eric | KALA | Stock Option (right to buy) | D | 16,62 | 150 000 | 150 000 | |||||
| 2018-03-02 | 2018-02-28 | 4 | PERRY GREGORY D | KALA | Stock Option (right to buy) | D | 14,05 | 25 920 | 25 920 | |||||
| 2018-03-02 | 2018-02-28 | 4 | Chen Hongming | KALA | Stock Option (right to buy) | D | 2,24 | −5 769 | 0 | |||||
| 2018-03-02 | 2018-02-28 | 4 | Chen Hongming | KALA | Stock Option (right to buy) | D | 2,30 | −4 000 | 106 236 | |||||
| 2018-03-02 | 2018-02-28 | 4 | Chen Hongming | KALA | Common Stock | D | 2,2400 | 5 769 | 13 | 55 849 | ||||
| 2018-03-02 | 2018-02-28 | 4 | Chen Hongming | KALA | Common Stock | D | 2,3000 | 4 000 | 9 | 50 080 | ||||
| 2018-02-12 | 2018-02-08 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 12,9300 | 25 000 | 323 | 3 447 840 | ||||
| 2018-02-09 | 2018-02-07 | 4 | LaRussa Michele | KALA | Stock Option (right to buy) | D | 12,86 | 8 000 | 8 000 | |||||
| 2018-02-09 | 2018-02-07 | 4 | Reumuth Mary | KALA | Stock Option (right to buy) | D | 12,86 | 70 000 | 70 000 | |||||
| 2018-02-09 | 2018-02-07 | 4 | Chen Hongming | KALA | Stock Option (right to buy) | D | 12,86 | 70 000 | 70 000 | |||||
| 2018-02-09 | 2018-02-07 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 12,86 | 70 000 | 70 000 | |||||
| 2018-02-09 | 2018-02-07 | 4 | Iwicki Mark T | KALA | Stock Option (right to buy) | D | 12,86 | 230 000 | 230 000 | |||||
| 2018-02-09 | 2018-02-07 | 4 | Bazemore Todd | KALA | Stock Option (right to buy) | D | 12,86 | 25 000 | 25 000 | |||||
| 2018-02-06 | 2018-02-02 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 14,7300 | 37 840 | 557 | 3 422 840 | ||||
| 2018-02-02 | 2018-02-01 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 14,9900 | 22 840 | 342 | 3 385 000 | ||||
| 2018-02-02 | 2018-01-31 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 15,0000 | 339 400 | 5 091 | 3 362 160 | ||||
| 2018-01-30 | 2018-01-29 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 14,9900 | 50 000 | 750 | 3 022 760 | ||||
| 2018-01-30 | 2018-01-26 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 14,9300 | 22 760 | 340 | 2 972 760 | ||||
| 2018-01-24 | 2018-01-24 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 14,9100 | 64 637 | 964 | 2 950 000 | ||||
| 2018-01-24 | 2018-01-23 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 14,9900 | 4 363 | 65 | 2 885 363 | ||||
| 2018-01-24 | 2018-01-22 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 14,9800 | 75 000 | 1 124 | 2 881 000 | ||||
| 2018-01-24 | 2018-01-19 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 14,9500 | 74 931 | 1 120 | 2 806 000 | ||||
| 2018-01-24 | 2018-01-12 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 14,5000 | 38 354 | 556 | 2 731 069 | ||||
| 2018-01-12 | 3 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 4 904 462 | ||||||||
| 2018-01-12 | 3 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 4 904 462 | ||||||||
| 2018-01-12 | 3 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 4 904 462 | ||||||||
| 2018-01-12 | 3 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 4 904 462 | ||||||||
| 2018-01-12 | 2018-01-12 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 15,4000 | 28 446 | 438 | 2 692 715 | ||||
| 2018-01-12 | 2018-01-11 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 13,6500 | 41 700 | 569 | 2 664 269 | ||||
| 2018-01-12 | 2018-01-10 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 12,8300 | 170 338 | 2 185 | 2 622 569 | ||||
| 2017-11-21 | 2017-11-20 | 4 | Bazemore Todd | KALA | Stock Option (right to buy) | D | 19,60 | 19,6000 | 172 000 | 3 371 | 172 000 | |||
| 2017-10-02 | 2017-09-28 | 4 | KOVEN ANDREW I | KALA | Stock Option (right to buy) | D | 23,08 | 25 920 | 25 920 | |||||
| 2017-08-15 | 2017-08-11 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 3,34 | −12 150 | 149 985 | |||||
| 2017-08-15 | 2017-08-11 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 2,30 | −44 313 | 18 247 | |||||
| 2017-08-15 | 2017-08-11 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 0,68 | −16 168 | 1 880 | |||||
| 2017-08-15 | 2017-08-11 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 0,68 | −36 094 | 0 | |||||
| 2017-08-15 | 2017-08-11 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 3,3400 | 12 150 | 41 | 108 725 | ||||
| 2017-08-15 | 2017-08-11 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 2,3000 | 44 313 | 102 | 96 575 | ||||
| 2017-08-15 | 2017-08-11 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 0,6800 | 16 168 | 11 | 52 262 | ||||
| 2017-08-15 | 2017-08-11 | 4 | Brazzell Romulus K | KALA | Common Stock | D | 0,6800 | 36 094 | 25 | 36 094 | ||||
| 2017-07-27 | 2017-07-25 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Series C Preferred Stock | I | −10 707 985 | 0 | ||||||
| 2017-07-27 | 2017-07-25 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 15,0000 | 319 333 | 4 790 | 2 375 279 | ||||
| 2017-07-27 | 2017-07-25 | 4 | ORBIMED ADVISORS LLC See Footnotes | KALA | Common Stock | I | 2 055 946 | 2 055 946 | ||||||
| 2017-07-27 | 2017-07-25 | 4 | Longitude Capital Partners II, LLC By Longitude Venture Partners II, L.P. | KALA | Series C Preferred Stock | I | −10 707 985 | 0 | ||||||
| 2017-07-27 | 2017-07-25 | 4 | Longitude Capital Partners II, LLC By Longitude Venture Partners II, L.P. | KALA | Common Stock | I | 15,0000 | 215 000 | 3 225 | 2 270 946 | ||||
| 2017-07-27 | 2017-07-25 | 4 | Longitude Capital Partners II, LLC By Longitude Venture Partners II, L.P. | KALA | Common Stock | I | 2 055 946 | 2 055 946 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | RA CAPITAL MANAGEMENT, LLC See footnotes | KALA | Series C Preferred Stock | I | −4 409 170 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | RA CAPITAL MANAGEMENT, LLC See footnotes | KALA | Series B Preferred Stock | I | −3 819 444 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | RA CAPITAL MANAGEMENT, LLC See footnotes | KALA | Common Stock | I | 15,0000 | 533 333 | 8 000 | 2 113 236 | ||||
| 2017-07-26 | 2017-07-25 | 4 | RA CAPITAL MANAGEMENT, LLC See footnotes | KALA | Common Stock | I | 1 579 903 | 1 579 903 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | TEPPER ROBERT I See footnote. | KALA | Common Stock Warrant (right to buy) | I | 7,50 | 33 333 | 33 333 | |||||
| 2017-07-26 | 2017-07-25 | 4 | TEPPER ROBERT I See footnote. | KALA | Series B Preferred Stock Warrant (right to buy) | I | −173 611 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | TEPPER ROBERT I See footnote. | KALA | Series B Preferred Stock | I | −2 265 764 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | TEPPER ROBERT I See footnote. | KALA | Series A Preferred Stock | I | −2 500 000 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | TEPPER ROBERT I See footnote. | KALA | Series Seed Preferred Stock | I | −3 677 374 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | TEPPER ROBERT I See footnote. | KALA | Common Stock | I | 1 621 092 | 1 621 092 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Shah Rajeev M. See footnote. | KALA | Series C Preferred Stock | I | −4 409 170 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Shah Rajeev M. See footnote. | KALA | Series B Preferred Stock | I | −3 819 444 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Shah Rajeev M. See footnote. | KALA | Common Stock | I | 15,0000 | 533 333 | 8 000 | 2 113 236 | ||||
| 2017-07-26 | 2017-07-25 | 4 | Shah Rajeev M. See footnote. | KALA | Common Stock | I | 1 579 903 | 1 579 903 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Grunberg Gregory By Longitude Venture Partners II, L.P. | KALA | Series C Preferred Stock | I | −10 707 985 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Grunberg Gregory By Longitude Venture Partners II, L.P. | KALA | Common Stock | I | 15,0000 | 215 000 | 3 225 | 2 270 946 | ||||
| 2017-07-26 | 2017-07-25 | 4 | Grunberg Gregory By Longitude Venture Partners II, L.P. | KALA | Common Stock | I | 2 055 946 | 2 055 946 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Paull Robert Bradley See footnote. | KALA | Common Stock Warrant (right to buy) | I | 7,50 | 16 152 | 16 152 | |||||
| 2017-07-26 | 2017-07-25 | 4 | Paull Robert Bradley See footnote. | KALA | Series B Preferred Stock Warrant (right to buy) | I | −84 130 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Paull Robert Bradley See footnote. | KALA | Series C Preferred Stock | I | −31 494 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Paull Robert Bradley See footnote. | KALA | Series B Preferred Stock | I | −900 146 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Paull Robert Bradley See footnote. | KALA | Series A Preferred Stock | I | −1 666 666 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Paull Robert Bradley See footnote. | KALA | Series Seed Preferred Stock | I | −3 677 373 | 0 | ||||||
| 2017-07-26 | 2017-07-25 | 4 | Paull Robert Bradley See footnote. | KALA | Common Stock | I | 1 204 937 | 1 204 937 | ||||||
| 2017-07-25 | 2017-07-25 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | KALA | Series C Convertible Preferred Stock | D | −4 409 170 | 0 | ||||||
| 2017-07-25 | 2017-07-25 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | KALA | Series B-1 Convertible Preferred Stock | D | −4 629 629 | 0 | ||||||
| 2017-07-25 | 2017-07-25 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | KALA | Common Stock | D | 846 566 | 846 566 | ||||||
| 2017-07-25 | 2017-07-25 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | KALA | Common Stock | D | 888 894 | 888 894 | ||||||
| 2017-07-21 | 2017-07-20 | 4/A | CDK ASSOCIATES, L.L.C. | KALA | Series C Convertible Preferred Stock | D | −2 858 086 | 0 | ||||||
| 2017-07-21 | 2017-07-20 | 4/A | CDK ASSOCIATES, L.L.C. | KALA | Common Stock | D | 15,0000 | 215 000 | 3 225 | 763 755 | ||||
| 2017-07-21 | 2017-07-20 | 4/A | CDK ASSOCIATES, L.L.C. | KALA | Common Stock | D | 548 755 | 548 755 | ||||||
| 2017-07-21 | 2017-07-20 | 4/A | CDK ASSOCIATES, L.L.C. | KALA | Series C Convertible Preferred Stock | D | −2 858 086 | 0 | ||||||
| 2017-07-21 | 2017-07-20 | 4/A | CDK ASSOCIATES, L.L.C. | KALA | Common Stock | D | 15,0000 | 215 000 | 3 225 | 763 755 | ||||
| 2017-07-21 | 2017-07-20 | 4/A | CDK ASSOCIATES, L.L.C. | KALA | Common Stock | D | 548 755 | 548 755 | ||||||
| 2017-07-21 | 2017-07-19 | 4 | Reumuth Mary | KALA | Stock Option (right to buy) | D | 15,00 | 28 973 | 28 973 | |||||
| 2017-07-21 | 2017-07-19 | 4 | Shah Rajeev M. | KALA | Stock Option (right to buy) | D | 15,00 | 12 960 | 12 960 | |||||
| 2017-07-21 | 2017-07-19 | 4 | Grunberg Gregory | KALA | Stock Option (right to buy) | D | 15,00 | 12 960 | 12 960 | |||||
| 2017-07-21 | 2017-07-19 | 4 | Paull Robert Bradley | KALA | Stock Option (right to buy) | D | 15,00 | 12 960 | 12 960 | |||||
| 2017-07-21 | 2017-07-19 | 4 | Hill Paulina | KALA | Stock Option (right to buy) | D | 15,00 | 12 960 | 12 960 | |||||
| 2017-07-21 | 2017-07-19 | 4 | Rosen Howard B | KALA | Stock Option (right to buy) | D | 15,00 | 12 960 | 12 960 | |||||
| 2017-07-21 | 2017-07-19 | 4 | TEPPER ROBERT I | KALA | Stock Option (right to buy) | D | 15,00 | 12 960 | 12 960 | |||||
| 2017-07-21 | 2017-07-19 | 4 | LANGER ROBERT | KALA | Stock Option (right to buy) | D | 15,00 | 12 960 | 12 960 | |||||
| 2017-07-21 | 2017-07-19 | 4 | Chen Hongming | KALA | Stock Option (right to buy) | D | 15,00 | 28 800 | 28 800 | |||||
| 2017-07-21 | 2017-07-19 | 4 | Brazzell Romulus K | KALA | Stock Option (right to buy) | D | 15,00 | 47 142 | 47 142 | |||||
| 2017-07-21 | 2017-07-19 | 4 | Iwicki Mark T | KALA | Stock Option (right to buy) | D | 15,00 | 78 632 | 78 632 | |||||
| 2017-07-20 | 2017-07-20 | 4 | CDK ASSOCIATES, L.L.C. | KALA | Common Stock | D | 15,0000 | 215 000 | 3 225 | 215 000 | ||||
| 2017-07-19 | 3 | LANGER ROBERT | KALA | Common Stock | D | 652 804 | ||||||||
| 2017-07-19 | 3 | LANGER ROBERT | KALA | Common Stock | D | 652 804 | ||||||||
| 2017-07-19 | 3 | Rosen Howard B | KALA | Common Stock | D | 6 480 | ||||||||
| 2017-07-19 | 3 | Rosen Howard B | KALA | Common Stock | D | 6 480 | ||||||||
| 2017-07-19 | 3 | Chen Hongming | KALA | Common Stock | D | 92 160 | ||||||||
| 2017-07-19 | 3 | Chen Hongming | KALA | Common Stock | D | 92 160 | ||||||||
| 2017-07-19 | 3 | Hanes Justin | KALA | Common Stock | D | 1 203 846 | ||||||||
| 2017-07-19 | 3 | Hanes Justin | KALA | Common Stock | D | 1 203 846 |
P
Köp på öppna marknaden eller privat köp av icke-derivatsäkerhet
S
Köp på öppna marknaden eller privat försäljning av icke-derivatsäkerhet
A
Bevilja, tilldelning eller annat förvärv av värdepapper från företaget (såsom en option)
C
Omvandling av derivat
D
Försäljning eller överföring av värdepapper tillbaka til företaget
F
Betalning av lösenpris eller skatteskuld med del av värdepapper som erhållits från bolaget
G
Överlåtelse av värdepapper från eller till insidern
K
Aktieswappar och liknande säkringsaffärer
M
Utövande eller omvandling av derivatsäkerhet som erhållits från företaget (som en option)
V
En transaktion friviligt rapporterad på schema 4
J
Andra (med en fotnot som beskriver transaktionen)
