| Utestående aktier | 4,872,497 shares |
| Insideraktier | 736 084 shares |
| Insynsägande | 15,11 % |
| Totalt antal insynspersoner | 41 |
Insider Sentiment Score
Insider sentiment score hittar de företag som köps av foretagsinsynspersoner.
Det är resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av insiderackumulation. Poängmodellen använder en kombination av nettoantalet insiders som köpt de föregående 90 dagarna, det totala antalet aktier som köpts i procent av aktiekapitalet och det totala antalet aktier som ägs av insiders. Siffran sträcker sig från 0 till 100, med högre siffror som indikerar en högre nivå av ackumulering för sina kamrater, och 50 är genomsnittet.
Uppdateringsfrekvens: Dagligen
Se Insiders Top Picks, som ger en lista över företag med högsta insiderackumulation.
Office Sentiment Score
Officersentiment Score hittar företag som köps av Corporate Officers.
Per definition Corporate Officers är Corporate Insiders, men till skillnad från vissa av de andra Insiders (10 % aktieägare och styrelseledamöter), arbetar ämbetsmän för företaget dagligen och de använder sina egna pengar när de handlar . (10 % aktieägare och styrelseledamöter är ofta fondförvaltare som förvaltar andras pengar.) Som sådan är insideraffärer som görs av tjänstemän mycket mer betydelsefulla och bör behandlas på lämpligt sätt.
Liksom Insider Sentiment Score är Officer Sentiment Score resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av officersackumulering.
Uppdateringsfrekvens: Dagligen
Se insiderns bästa val, vilket ger en lista över företag med högsta insider sentiment.
Viktiga insidernyckeltal
Denna kort visar hur företaget rankas längs olika insidernyckeltal. Procenttilrankningen visar hur detta företag jämförs med andra företag på USA-marknaden. Högre rankingar indikerar bättre situationer.
Till exempel anses det allmänt att insiderköp är en positiv indikator, så företag med mer insiderköp skulle rankas högre än företag med mindre insiderköp (eller til och med insiderförsäljning).
Procent av flytande köpta av insiders (ranking)
0.000 %( )
7642 out of 11220Procentandelen av aktier köpta av insiders är det totala antalet aktier som köpts av insiders minus det totala antalet aktier som sålts av insiders under de senaste 90 dagarna, dividerat med det totala antalet aktier och multiplicerat med 100.
Insiderhandelsdiagram
Calithera Biosciences, Inc. insideraffärer visas i följande diagram. Insiders är tjänstemän, styrelseledamöter eller betydande investerare i ett företag. I allmänhet är det i allmänhet olagligt för insiders att göra affärer i sina företag baserat på väsentlig, icke-offentlig information. Detta betyder inte att det är olagligt för dem att göra några affärer i sina egna företag. De måste dock rapportera alla affärer till SEC via ett formulär 4.
Insiderlista och lönsamhetsstatistik
Den här tabellen visar listan över kända insiders och genereras automatiskt från anmälningar som avslöjas till SEC. Förutom namnen, den senaste titeln och direktören, tjänstemannen eller ägarbeteckningen på 10 %, tillhandahåller vi de senaste avslöjade innehaven. Dessutom, när det är möjligt tillhandahåller vi insiderns historiska handelsresultat. Det historiska handelsresultatet är ett vägt genomsnitt av resultatet för faktiska köptransaktioner på den öppna marknaden som insidern gjort. För mer information om hur detta beräknas, titta på detta YouTube-webinarium.
See our leaderboard of most profitable insider traders.
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
|
Adage Capital Partners Gp, L.l.c.
10% Owner -
|
3 546 873 | 177 344 | |
| Sunil Agarwal Director - [D] | 0 | 0 | |
|
ATV Associates VIII, L.L.C.
10% Owner -
|
2 110 082 | 105 504 | |
|
Adage Capital Advisors, L.L.C.
10% Owner -
|
3 546 873 | 177 344 | |
|
Adage Capital Partners, L.P.
10% Owner -
|
3 546 873 | 177 344 | |
|
Advanced Technology Ventures VIII LP
10% Owner -
|
2 110 082 | 105 504 | |
|
Robert Atchinson
10% Owner -
|
3 546 873 | 177 344 | |
| Biotechnology Value Fund Ii Lp - | 480 432 | 24 022 | |
| Biotechnology Value Fund L P - | 480 432 | 24 022 | |
|
James J Bochnowski
10% Owner -
|
23 464 | 1 173 | |
|
Bvf Inc/il
10% Owner -
|
480 432 | 24 022 | |
|
Bvf Partners L P/il
10% Owner -
|
480 432 | 24 022 | |
| BVF Partners OS Ltd. - | 480 432 | 24 022 |
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
| Mark K Bennett SR. VP, RESEARCH - [O] | 10 413 | 521 | |
| Biotechnology Value Trading Fund OS LP - | 480 432 | 24 022 | |
|
Ralph E Christoffersen
Director, 10% Owner -
[D]
|
2 161 915 | 108 096 | |
|
Delphi Ventures Viii Lp
10% Owner -
|
23 464 | 1 173 | |
|
David L Douglass
10% Owner -
|
23 464 | 1 173 | |
| Jonathan G Drachman Director - [D] | 200 000 | 10 000 | |
|
Delphi BioInvestments VIII LP
10% Owner -
|
23 464 | 1 173 | |
|
Delphi Management Partners VIII, L.L.C.
10% Owner -
|
23 464 | 1 173 | |
| Garland J. Scott Director - [D] | 0 | 0 | |
|
Jean George
Director, 10% Owner -
[D]
|
2 110 082 | 105 504 | |
|
Phillip Gross
10% Owner -
|
3 546 873 | 177 344 | |
| Curtis Hecht CHIEF BUSINESS OFFICER - [O] | 92 321 | 4 616 | |
| Suzy Jones Director - [D] | 14 394 | 720 | |
| Emil Kuriakose CHIEF MEDICAL OFFICER - [O] | 3 539 | 3 539 |
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
|
Mark N Lampert
10% Owner -
|
480 432 | 24 022 | |
|
Morgenthaler Venture Partners Ix Lp
10% Owner -
|
2 161 915 | 108 096 | |
| Christopher Molineaux SR. VP, DEVELOPMENT - [O] | 27 859 | 27 859 | |
| Susan Molineaux PRESIDENT & CEO, Director - [D] [O] | 27 859 | 27 859 | |
| Keith Orford Director - [O] | 66 094 | 3 305 | |
|
Deepika Pakianathan
Director, 10% Owner -
[D]
|
0 | 0 | |
| Francesco Parlati SR. VP, RESEARCH - [O] | 140 998 | 7 050 | |
|
Douglas A Roeder
10% Owner -
|
23 464 | 1 173 | |
| Sumita Ray See Remarks - [O] | 105 000 | 5 250 | |
| Eric Sjogren SR. VP, DRUG DISCOVERY - [O] | 8 467 | 8 467 | |
| Waddill William D. SR. VP & CFO - [O] | 17 485 | 874 | |
| Blake Wise Director - [D] | 0 | 0 | |
| Henry Ward Wolff Director - [D] | 0 | 0 | |
| Stephanie Wong See Remarks - [O] | 6 287 | 6 287 |
Report errors via our new Insider Auditing Tool
Track Records av insiderköp - Kortsiktig vinstanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i CALA / Calithera Biosciences, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste köpen på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Track Records av insiderförsäljning - Kortsiktig förlustanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i CALA / Calithera Biosciences, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste försäljningarna på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Transaktionshistorik
Klicka på länkikonen för att se hela transaktionshistoriken. Transaktioner som rapporteras som en del av en automatisk handelsplan 10b5-1 kommer att ha ett X i kolumnen markerad 10b-5.
| Fil datum |
Handel datum |
Schema | Insider | Ticker | Värdepappertitel | Kod | Direkta | Utövningspris | Enhet pris |
Enheter ändrad |
Värde ändrad (1K) |
Kvarvarande Optioner |
Kvarvarande Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01-31 | 2023-01-27 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 0,3858 | −1 172 | −0 | 0 | ||||
| 2023-01-31 | 2023-01-27 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 0,3858 | −120 161 | −46 | 0 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,4461 | −317 | −0 | 6 287 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | 0,4461 | −526 | −0 | 27 859 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | 0,4461 | −217 | −0 | 27 859 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,4461 | −79 | −0 | 3 539 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,4461 | −279 | −0 | 8 467 | ||||
| 2022-01-27 | 2022-01-25 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 597 475 | 597 475 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Ray Sumita | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165 000 | 165 000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 215 000 | 215 000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165 000 | 165 000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165 000 | 165 000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165 000 | 165 000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Orford Keith | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 40 000 | 40 000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Kuriakose Emil | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 215 000 | 215 000 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,4915 | −4 794 | −2 | 172 434 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,4915 | −666 | −0 | 67 369 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,4915 | −5 586 | −3 | 132 085 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,4915 | −4 794 | −2 | 140 998 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,6604 | −18 077 | −12 | 145 792 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,6604 | −18 077 | −12 | 137 671 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,6604 | −18 077 | −12 | 177 228 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,6604 | −3 855 | −3 | 68 035 | ||||
| 2021-11-12 | 2021-11-11 | 4 | Orford Keith | CALA | Common Stock | D | 0,8800 | −48 190 | −42 | 66 094 | ||||
| 2021-11-12 | 2021-11-10 | 4 | Orford Keith | CALA | Common Stock | D | 0,8565 | −30 000 | −26 | 114 284 | ||||
| 2021-11-10 | 2021-11-10 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | 0,8467 | 100 000 | 85 | 557 188 | ||||
| 2021-11-10 | 2021-11-10 | 4 | DRACHMAN JONATHAN G | CALA | Common Stock | D | 0,8595 | 200 000 | 172 | 200 000 | ||||
| 2021-11-10 | 2021-11-10 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | 0,8467 | 100 000 | 85 | 557 188 | ||||
| 2021-11-09 | 2021-11-09 | 4 | Orford Keith | CALA | Common Stock | D | 0,8400 | −51 810 | −44 | 144 284 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Orford Keith | CALA | Common Stock | D | 30 000 | 196 094 | ||||||
| 2021-11-09 | 2021-11-05 | 4 | Molineaux Christopher | CALA | Common Stock | D | 12 000 | 102 500 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,8700 | −15 566 | −14 | 195 305 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Sjogren Eric | CALA | Common Stock | D | 30 000 | 210 871 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,8700 | −15 566 | −14 | 155 748 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Wong Stephanie | CALA | Common Stock | D | 30 000 | 171 314 | ||||||
| 2021-11-09 | 2021-11-05 | 4 | Ray Sumita | CALA | Common Stock | D | 12 000 | 105 000 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,8700 | −3 077 | −3 | 69 390 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Kuriakose Emil | CALA | Common Stock | D | 12 000 | 72 467 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,8700 | −15 566 | −14 | 163 869 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Parlati Francesco | CALA | Common Stock | D | 30 000 | 179 435 | ||||||
| 2021-11-09 | 3 | Kuriakose Emil | CALA | Common Stock | D | 60 467 | ||||||||
| 2021-10-29 | 2021-10-28 | 4 | Sjogren Eric | CALA | Common Stock | D | 1,8900 | −45 965 | −87 | 180 871 | ||||
| 2021-10-29 | 2021-10-27 | 4 | Sjogren Eric | CALA | Common Stock | D | 90 000 | 226 836 | ||||||
| 2021-10-29 | 2021-10-27 | 4 | Molineaux Christopher | CALA | Common Stock | D | 36 000 | 90 500 | ||||||
| 2021-10-29 | 2021-10-27 | 4 | Orford Keith | CALA | Common Stock | D | 90 000 | 166 094 | ||||||
| 2021-10-29 | 2021-10-28 | 4 | Wong Stephanie | CALA | Common Stock | D | 1,8900 | −45 965 | −87 | 141 314 | ||||
| 2021-10-29 | 2021-10-27 | 4 | Wong Stephanie | CALA | Common Stock | D | 90 000 | 187 279 | ||||||
| 2021-10-29 | 2021-10-28 | 4 | Parlati Francesco | CALA | Common Stock | D | 1,8900 | −45 965 | −87 | 149 435 | ||||
| 2021-10-29 | 2021-10-27 | 4 | Parlati Francesco | CALA | Common Stock | D | 90 000 | 195 400 | ||||||
| 2021-10-29 | 2021-10-27 | 4 | Ray Sumita | CALA | Common Stock | D | 36 000 | 93 000 | ||||||
| 2021-06-14 | 2021-06-11 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 2,28 | 20 000 | 20 000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 2,28 | 20 000 | 20 000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 2,28 | 20 000 | 20 000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Garland J. Scott | CALA | Stock Option (Right to Buy) | D | 2,28 | 20 000 | 20 000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 2,28 | 20 000 | 20 000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 2,28 | 20 000 | 20 000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 2,28 | 20 000 | 20 000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 2,28 | 20 000 | 20 000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 150 000 | 150 000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Hecht Curtis | CALA | Common Stock | D | 30 000 | 92 321 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Hecht Curtis | CALA | Common Stock | D | 35 000 | 62 321 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125 000 | 125 000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 12 000 | 52 000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 30 000 | 40 000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 375 000 | 375 000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 85 000 | 95 000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Ray Sumita | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125 000 | 125 000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Ray Sumita | CALA | Common Stock | D | 12 000 | 57 000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Ray Sumita | CALA | Common Stock | D | 30 000 | 45 000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Orford Keith | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 150 000 | 150 000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Orford Keith | CALA | Common Stock | D | 30 000 | 76 094 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Orford Keith | CALA | Common Stock | D | 35 000 | 46 094 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125 000 | 125 000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 30 000 | 105 400 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 30 000 | 105 400 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125 000 | 125 000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Sjogren Eric | CALA | Common Stock | D | 30 000 | 134 336 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Sjogren Eric | CALA | Common Stock | D | 30 000 | 134 336 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 150 000 | 150 000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Wong Stephanie | CALA | Common Stock | D | 30 000 | 103 156 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Wong Stephanie | CALA | Common Stock | D | 35 000 | 73 156 | ||||||
| 2020-12-18 | 2020-12-16 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | −2 447 | −15 | 11 094 | ||||
| 2020-08-04 | 2020-07-31 | 4 | Garland J. Scott | CALA | Stock Option (Right to Buy) | D | 4,70 | 40 000 | 40 000 | |||||
| 2020-07-14 | 3 | Garland J. Scott | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2020-06-11 | 2020-06-09 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,25 | 20 000 | 20 000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 5,25 | 20 000 | 20 000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 5,25 | 20 000 | 20 000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 5,25 | 20 000 | 20 000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 5,25 | 20 000 | 20 000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 5,25 | 20 000 | 20 000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 5,25 | 20 000 | 20 000 | |||||
| 2020-05-26 | 2020-05-21 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 6,0000 | −192 250 | −1 154 | 480 432 | ||||
| 2020-05-26 | 2020-05-21 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 6,0000 | −1 064 332 | −6 386 | 2 766 561 | ||||
| 2020-05-26 | 2020-05-21 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 6,0000 | −1 027 016 | −6 162 | 3 712 340 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Wong Stephanie | CALA | Common Stock | D | 8,0000 | −5 000 | −40 | 30 082 | ||||
| 2020-02-24 | 2020-02-20 | 4 | Orford Keith | CALA | Common Stock | D | 8,0000 | −3 021 | −24 | 8 541 | ||||
| 2020-01-22 | 2020-01-18 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 400 000 | 400 000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 110 000 | 110 000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 120 000 | 120 000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 7,41 | 110 000 | 110 000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 120 000 | 120 000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 110 000 | 110 000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 75 000 | 75 000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 7,41 | 140 000 | 140 000 | |||||
| 2019-12-26 | 2019-12-23 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | −3 021 | −18 | 11 562 | ||||
| 2019-11-22 | 2019-11-20 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,9116 | 14 151 | 55 | 672 682 | ||||
| 2019-11-22 | 2019-11-20 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,9116 | 79 285 | 310 | 3 830 893 | ||||
| 2019-11-22 | 2019-11-20 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,9116 | 98 518 | 385 | 4 739 356 | ||||
| 2019-11-18 | 2019-11-14 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,3700 | 11 105 | 37 | 658 531 | ||||
| 2019-11-18 | 2019-11-14 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,3700 | 45 888 | 155 | 3 751 608 | ||||
| 2019-11-18 | 2019-11-14 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,3700 | 71 495 | 241 | 4 640 838 | ||||
| 2019-10-31 | 2019-10-30 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,7000 | 57 868 | 156 | 647 426 | ||||
| 2019-10-31 | 2019-10-30 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,7000 | 331 048 | 894 | 3 705 720 | ||||
| 2019-10-31 | 2019-10-30 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,7000 | 408 592 | 1 103 | 4 569 343 | ||||
| 2019-10-31 | 2019-10-29 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,6000 | 116 552 | 303 | 589 558 | ||||
| 2019-10-31 | 2019-10-29 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,6000 | 610 052 | 1 586 | 3 374 672 | ||||
| 2019-10-31 | 2019-10-29 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,6000 | 872 373 | 2 268 | 4 160 751 | ||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 814 382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 814 382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 290 624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6 999 010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 814 382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 290 624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6 999 010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 814 382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 290 624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6 999 010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 814 382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 290 624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6 999 010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 814 382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 290 624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6 999 010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 814 382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 290 624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6 999 010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 290 624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6 999 010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 814 382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 290 624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6 999 010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 814 382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9 290 624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6 999 010 | ||||||||
| 2019-06-27 | 2019-06-25 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | 3,8800 | 51 600 | 200 | 457 188 | ||||
| 2019-06-27 | 2019-06-25 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | 3,8800 | 51 600 | 200 | 457 188 | ||||
| 2019-06-26 | 2019-06-24 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −21 739 | 0 | |||||
| 2019-06-26 | 2019-06-24 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,9600 | 21 739 | 21 | 72 057 | ||||
| 2019-06-21 | 2019-06-19 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −10 000 | 13 284 | |||||
| 2019-06-21 | 2019-06-19 | 4 | Wong Stephanie | CALA | Common Stock | D | 2,6400 | 10 000 | 26 | 31 751 | ||||
| 2019-06-19 | 2019-06-17 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | −417 | −3 | 12 083 | ||||
| 2019-06-19 | 2019-06-17 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −6 246 | 0 | |||||
| 2019-06-19 | 2019-06-17 | 4 | Parlati Francesco | CALA | Common Stock | D | 2,6400 | 6 246 | 16 | 42 201 | ||||
| 2019-06-03 | 2019-05-30 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 5,42 | 11 000 | 11 000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,42 | 11 000 | 11 000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 5,42 | 11 000 | 11 000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 5,42 | 11 000 | 11 000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 5,42 | 11 000 | 11 000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 5,42 | 11 000 | 11 000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 5,42 | 11 000 | 11 000 | |||||
| 2019-05-24 | 2019-05-22 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | −416 | −2 | 10 000 | ||||
| 2019-04-17 | 2019-04-15 | 4 | Orford Keith | CALA | Common Stock | D | 6,3300 | −416 | −3 | 10 416 | ||||
| 2019-03-19 | 2019-03-15 | 4 | Orford Keith | CALA | Common Stock | D | 6,4300 | −417 | −3 | 10 832 | ||||
| 2019-03-13 | 2019-03-11 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | −1 565 | −9 | 11 249 | ||||
| 2019-02-11 | 2019-02-07 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | −12 986 | 395 588 | ||||||
| 2019-02-11 | 2019-02-07 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | −12 986 | 395 588 | ||||||
| 2019-01-14 | 2019-01-10 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 4,64 | 90 000 | 90 000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 120 000 | 120 000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 117 000 | 117 000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 4,64 | 132 000 | 132 000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 390 000 | 390 000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 47 000 | 47 000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 100 000 | 100 000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 105 000 | 105 000 | |||||
| 2018-11-16 | 2018-11-14 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | −6 476 | 408 574 | ||||||
| 2018-11-16 | 2018-11-14 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | −6 476 | 408 574 | ||||||
| 2018-10-17 | 2018-10-15 | 4 | Orford Keith | CALA | Common Stock | D | 6,0500 | −313 | −2 | 10 314 | ||||
| 2018-10-15 | 2018-10-11 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | −1 252 | −8 | 10 627 | ||||
| 2018-10-11 | 2018-10-09 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 5,61 | 25 000 | 25 000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 5,15 | 11 000 | 11 000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,15 | 11 000 | 11 000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 5,15 | 11 000 | 11 000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 5,15 | 11 000 | 11 000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 5,15 | 11 000 | 11 000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 5,15 | 11 000 | 11 000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 5,15 | 11 000 | 11 000 | |||||
| 2018-04-05 | 2018-04-03 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | −8 601 | 0 | |||||
| 2018-04-05 | 2018-04-03 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | −8 209 | 0 | |||||
| 2018-04-05 | 2018-04-03 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,4800 | 16 810 | 8 | 42 818 | ||||
| 2018-03-06 | 3/A | Parlati Francesco | CALA | Common Stock | D | 20 349 | ||||||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −3 116 | 0 | |||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −1 979 | 0 | |||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 3 116 | 3 | 28 455 | ||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 1 979 | 2 | 25 339 | ||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | −26 992 | 9 729 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −6 798 | 0 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 6 798 | 18 | 21 000 | ||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | −6 798 | 0 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −26 992 | 9 729 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 26 992 | 71 | 44 860 | ||||
| 2018-02-27 | 2018-02-23 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −10 000 | 21 596 | |||||
| 2018-02-27 | 2018-02-23 | 4 | Wong Stephanie | CALA | Common Stock | D | 2,6400 | 10 000 | 26 | 15 000 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −3 116 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −1 979 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 3 116 | 3 | 20 488 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 1 979 | 2 | 17 372 | ||||
| 2018-01-16 | 2018-01-11 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 60 000 | 60 000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 8,60 | 70 000 | 70 000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 65 000 | 65 000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 200 000 | 200 000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 70 000 | 70 000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 30 000 | 30 000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 70 000 | 70 000 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | −5 300 | 34 030 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | −7 568 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −2 700 | 6 006 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −6 502 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 2 700 | 7 | 11 702 | ||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 6 502 | 6 | 9 002 | ||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | −2 700 | 6 006 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | −6 502 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −5 300 | 34 030 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −7 568 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 5 300 | 14 | 15 368 | ||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 7 568 | 7 | 10 068 | ||||
| 2017-10-03 | 3 | Ray Sumita | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2017-10-03 | 2017-09-29 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 15,75 | 75 000 | 75 000 | |||||
| 2017-10-03 | 2017-09-20 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 15,75 | 22 000 | 22 000 | |||||
| 2017-09-28 | 2017-09-28 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 15,5000 | −38 000 | −589 | 3 546 873 | ||||
| 2017-09-28 | 2017-09-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 15,5900 | −186 000 | −2 900 | 3 584 873 | ||||
| 2017-09-28 | 2017-09-26 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 15,6800 | −352 000 | −5 519 | 3 770 873 | ||||
| 2017-09-21 | 3 | Wise Blake | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2017-07-19 | 2017-07-17 | 4 | Wong Stephanie By Trust | CALA | Common Stock | I | 18,4078 | −3 552 | −65 | 10 550 | ||||
| 2017-07-19 | 2017-07-17 | 4 | Orford Keith | CALA | Common Stock | D | 18,3126 | −2 120 | −39 | 6 879 | ||||
| 2017-07-07 | 2017-07-06 | 4 | Hecht Curtis | CALA | Common Stock | D | 18,0000 | −700 | −13 | 15 940 | ||||
| 2017-06-13 | 2017-06-09 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 14,20 | 11 000 | 11 000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 14,20 | 11 000 | 11 000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 14,20 | 11 000 | 11 000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 14,20 | 11 000 | 11 000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 14,20 | 11 000 | 11 000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 14,20 | 11 000 | 11 000 | |||||
| 2017-05-23 | 2017-05-19 | 4 | Hecht Curtis | CALA | Common Stock | D | 16,0000 | −650 | −10 | 14 910 | ||||
| 2017-03-24 | 2017-03-22 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 10,2500 | 487 804 | 5 000 | 4 122 873 | ||||
| 2017-03-15 | 2017-03-13 | 4 | Hecht Curtis | CALA | Common Stock | D | 14,0000 | −600 | −8 | 15 560 | ||||
| 2017-03-06 | 2017-03-02 | 4 | Hecht Curtis | CALA | Common Stock | D | 12,0000 | −550 | −7 | 16 160 | ||||
| 2017-01-06 | 3 | Parlati Francesco | CALA | Common Stock | D | 24 764 | ||||||||
| 2017-01-06 | 3 | Parlati Francesco | CALA | Common Stock | D | 24 764 | ||||||||
| 2017-01-06 | 3 | Wong Stephanie By Trust | CALA | Common Stock | I | 28 204 | ||||||||
| 2017-01-06 | 3 | Wong Stephanie By Trust | CALA | Common Stock | I | 28 204 | ||||||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | −4 749 | 9 498 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | −5 418 | 6 502 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −15 627 | 42 021 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −6 306 | 7 568 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 15 627 | 41 | 23 810 | ||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 6 306 | 6 | 8 183 | ||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | −15 627 | 42 021 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | −6 306 | 7 568 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −4 749 | 9 498 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −5 418 | 6 502 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 4 749 | 13 | 12 044 | ||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 5 418 | 5 | 7 295 | ||||
| 2016-12-01 | 2016-11-29 | 4 | Waddill William D. | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75 000 | 75 000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 165 000 | 165 000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75 000 | 75 000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75 000 | 75 000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75 000 | 75 000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Bennett Mark K | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 56 250 | 56 250 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 3,35 | 75 000 | 75 000 | |||||
| 2016-11-17 | 2016-11-16 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 3,1500 | 500 000 | 1 575 | 3 635 069 | ||||
| 2016-10-03 | 2016-09-29 | 4 | Waddill William D. | CALA | Common Stock | D | −17 485 | 17 485 | ||||||
| 2016-08-11 | 3 | JONES SUZY | CALA | Common Stock | D | 14 394 | ||||||||
| 2016-08-11 | 3 | JONES SUZY | CALA | Common Stock | D | 14 394 | ||||||||
| 2016-08-11 | 2016-08-09 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 3,26 | 22 000 | 22 000 | |||||
| 2016-08-10 | 2016-08-08 | 4 | Hecht Curtis | CALA | Common Stock | D | 3 085 | 14 210 | ||||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | −4 749 | 14 247 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | −7 586 | 11 920 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −16 146 | 47 919 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −8 829 | 13 874 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | −4 410 | 0 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 16 146 | 43 | 31 885 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 8 829 | 8 | 15 739 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 4 410 | 2 | 6 910 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | −16 146 | 47 919 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | −8 829 | 13 874 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,48 | −4 410 | 0 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −4 749 | 14 247 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −7 586 | 11 920 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 4 749 | 13 | 14 835 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 7 586 | 7 | 10 086 | ||||
| 2016-06-16 | 2016-06-14 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 4,76 | 11 000 | 11 000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 4,76 | 11 000 | 11 000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 4,76 | 11 000 | 11 000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 4,76 | 11 000 | 11 000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 4,76 | 11 000 | 11 000 | |||||
| 2016-05-03 | 3 | Orford Keith | CALA | Common Stock | D | 4 240 | ||||||||
| 2016-05-03 | 3 | Orford Keith | CALA | Common Stock | D | 4 240 | ||||||||
| 2016-05-03 | 2016-05-02 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 5,33 | 5 000 | 5 000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Bennett Mark K | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70 000 | 70 000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70 000 | 70 000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 32 500 | 32 500 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 185 000 | 185 000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70 000 | 70 000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Waddill William D. | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70 000 | 70 000 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 2,64 | −4 749 | 18 998 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,96 | −2 835 | 8 034 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | −1 612 | 807 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | −1 217 | 0 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 2,6400 | 4 749 | 13 | 10 413 | ||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,9600 | 2 835 | 3 | 5 664 | ||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 1 612 | 1 | 2 829 | ||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 1 217 | 1 | 1 217 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | −4 749 | 18 996 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | −5 418 | 19 506 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −11 640 | 73 794 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −6 306 | 22 703 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | −5 512 | 4 410 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | −4 367 | 0 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 11 640 | 31 | 109 112 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 6 306 | 6 | 97 472 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 5 512 | 3 | 91 166 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 4 367 | 2 | 85 654 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | −11 640 | 73 794 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | −6 306 | 22 703 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,48 | −5 512 | 4 410 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,48 | −4 367 | 0 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | −4 749 | 18 996 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | −5 418 | 19 506 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 4 749 | 13 | 39 542 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 5 418 | 5 | 34 793 | ||||
| 2015-11-18 | 2015-11-16 | 4 | Hecht Curtis | CALA | Common Stock | D | 6,5820 | −970 | −6 | 8 625 | ||||
| 2015-09-30 | 3 | AGARWAL SUNIL | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2015-09-30 | 2015-09-29 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,00 | 22 000 | 22 000 | |||||
| 2015-09-24 | 2015-09-23 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,0687 | 40 168 | 244 | 3 135 069 | ||||
| 2015-09-24 | 2015-09-22 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,0033 | 41 800 | 251 | 3 094 901 | ||||
| 2015-09-24 | 2015-09-22 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 5,9977 | 25 000 | 150 | 3 053 101 | ||||
| 2015-09-08 | 2015-09-04 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,9500 | 2 300 | 14 | 3 028 101 | ||||
| 2015-09-08 | 2015-09-03 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 5,9300 | 88 000 | 522 | 3 025 801 | ||||
| 2015-08-28 | 2015-08-28 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,5800 | 22 000 | 123 | 2 937 801 | ||||
| 2015-08-28 | 2015-08-28 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,5500 | 20 700 | 115 | 2 915 801 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,3500 | 32 400 | 173 | 2 895 101 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,1700 | 29 089 | 150 | 2 862 701 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,5800 | 19 578 | 109 | 2 833 612 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,4300 | 6 253 | 34 | 2 814 034 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,4100 | 9 848 | 53 | 2 807 781 | ||||
| 2015-08-28 | 2015-08-26 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 4,6500 | 32 058 | 149 | 2 797 933 | ||||
| 2015-08-28 | 2015-08-26 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 4,7000 | 200 | 1 | 2 765 875 | ||||
| 2015-08-24 | 2015-08-20 | 4 | Hecht Curtis | CALA | Stock Option (Right to Buy) | D | 2,64 | −2 000 | 43 378 | |||||
| 2015-08-24 | 2015-08-20 | 4 | Hecht Curtis | CALA | Common Stock | D | 2,6400 | 2 000 | 5 | 8 625 | ||||
| 2015-07-16 | 2015-07-14 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 2,64 | −13 125 | 61 880 | |||||
| 2015-07-16 | 2015-07-14 | 4 | Waddill William D. | CALA | Common Stock | D | 2,6400 | 13 125 | 35 | 15 625 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan By Spouse | CALA | Stock Option (Right to Buy) | I | 2,64 | −10 288 | 23 745 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan By Spouse | CALA | Stock Option (Right to Buy) | I | 0,96 | −14 087 | 24 924 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 2,64 | −30 279 | 85 434 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 0,96 | −16 396 | 29 009 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 0,48 | −14 330 | 9 922 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 0,48 | −15 282 | 4 367 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 30 279 | 80 | 78 787 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 16 396 | 16 | 48 508 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 14 330 | 7 | 32 112 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 15 282 | 7 | 17 782 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 2,64 | −30 279 | 85 434 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 0,96 | −16 396 | 29 009 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 0,48 | −14 330 | 9 922 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 0,48 | −15 282 | 4 367 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Stock Option (Right to Buy) | D | 2,64 | −10 288 | 23 745 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Stock Option (Right to Buy) | D | 0,96 | −14 087 | 24 924 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 10 288 | 27 | 26 875 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 14 087 | 14 | 16 587 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 2,64 | −7 912 | 23 747 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,96 | −4 726 | 10 869 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | −2 688 | 2 419 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | −3 039 | 1 217 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 2,6400 | 7 912 | 21 | 19 501 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,9600 | 4 726 | 5 | 11 589 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 2 688 | 1 | 6 863 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 3 039 | 1 | 4 175 | ||||
| 2015-06-11 | 2015-06-09 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 7,99 | 11 000 | 33 000 | |||||
| 2015-06-11 | 2015-06-09 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 7,99 | 11 000 | 11 000 | |||||
| 2015-06-11 | 2015-06-09 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 7,99 | 11 000 | 39 355 | |||||
| 2015-06-10 | 2015-06-09 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 7,99 | 11 000 | 11 000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 16,40 | 45 000 | 45 000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 16,40 | 227 346 | 227 346 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 16,40 | 45 000 | 45 000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Hecht Curtis | CALA | Stock Option (Right to Buy) | D | 16,40 | 25 000 | 25 000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Molineaux Christopher | CALA | Stock Option (Right to Buy) | D | 16,40 | 45 000 | 45 000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Sjogren Eric | CALA | Stock Option (Right to Buy) | D | 16,40 | 45 000 | 45 000 | |||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 7,20 | 1 171 | 17 569 | |||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 2,64 | 5 626 | 75 005 | |||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. By Trust | CALA | Common Stock | I | 7,2000 | 1 171 | 8 | 16 172 | ||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. By Trust | CALA | Common Stock | I | 2,6400 | 5 626 | 15 | 15 001 | ||||
| 2014-12-09 | 3 | Wolff Henry Ward | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2014-12-09 | 2014-12-02 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 9,64 | 22 000 | 22 000 | |||||
| 2014-10-15 | 2014-10-15 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,8000 | 25 000 | 170 | 2 765 675 | ||||
| 2014-10-15 | 2014-10-15 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 7,2500 | 13 000 | 94 | 2 740 675 | ||||
| 2014-10-15 | 2014-10-14 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,9900 | 25 000 | 175 | 2 727 375 | ||||
| 2014-10-15 | 2014-10-14 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 7,0000 | 30 000 | 210 | 2 702 375 | ||||
| 2014-10-15 | 2014-10-13 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 6,9400 | 88 700 | 616 | 2 672 375 | ||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series D Preferred Stock | I | 7 282 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series D Preferred Stock | I | 745 825 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series C Preferred Stock | I | 7 228 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series C Preferred Stock | I | 740 312 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series B Preferred Stock | I | 4 053 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series B Preferred Stock | I | 415 128 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series A Preferred Stock | I | 66 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series A Preferred Stock | I | 6 808 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 10,0000 | 4 835 | 48 | 23 464 | ||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 10,0000 | 495 165 | 4 952 | 2 403 238 | ||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 18 629 | 18 629 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 1 908 073 | 1 908 073 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES D PREFERRED STOCK | I | 634 195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES C PREFERRED STOCK | I | 747 540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES B PREFERRED STOCK | I | 419 181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES A PREFERRED STOCK | I | 9 166 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean By Partnership | CALA | COMMON STOCK | I | 10,0000 | 300 000 | 3 000 | 2 110 082 | ||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean By Partnership | CALA | COMMON STOCK | I | 1 810 082 | 1 810 082 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES D PREFERRED STOCK | I | 634 195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES C PREFERRED STOCK | I | 747 540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES B PREFERRED STOCK | I | 419 181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES A PREFERRED STOCK | I | 10 999 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E By Partnership | CALA | COMMON STOCK | I | 10,0000 | 350 000 | 3 500 | 2 161 915 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E By Partnership | CALA | COMMON STOCK | I | 1 811 915 | 1 811 915 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES D PREFERRED STOCK | D | 634 195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES C PREFERRED STOCK | D | 747 540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES B PREFERRED STOCK | D | 419 181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES A PREFERRED STOCK | D | 10 999 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | COMMON STOCK | D | 10,0000 | 350 000 | 3 500 | 2 161 915 | ||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | COMMON STOCK | D | 10,0000 | 1 811 915 | 18 119 | 1 811 915 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series D Preferred Stock | I | 7 282 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series D Preferred Stock | I | 745 825 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series C Preferred Stock | I | 7 228 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series C Preferred Stock | I | 740 312 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series B Preferred Stock | I | 4 053 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series B Preferred Stock | I | 415 128 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series A Preferred Stock | I | 66 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series A Preferred Stock | I | 6 808 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 10,0000 | 4 835 | 48 | 23 464 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 10,0000 | 495 165 | 4 952 | 2 403 238 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 18 629 | 18 629 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 1 908 073 | 1 908 073 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES D PREFERRED STOCK | D | 634 195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES C PREFERRED STOCK | D | 747 540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES B PREFERRED STOCK | D | 419 181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES A PREFERRED STOCK | D | 9 166 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | COMMON STOCK | D | 10,0000 | 300 000 | 3 000 | 2 110 082 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | COMMON STOCK | D | 1 810 082 | 1 810 082 | ||||||
| 2014-10-03 | 2014-10-01 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 10,0000 | 800 000 | 8 000 | 2 583 675 | ||||
| 2014-10-01 | 3 | Waddill William D. By Trust | CALA | COMMON STOCK | I | 18 750 | ||||||||
| 2014-10-01 | 3 | Waddill William D. By Trust | CALA | COMMON STOCK | I | 18 750 | ||||||||
| 2014-10-01 | 3 | Hecht Curtis | CALA | COMMON STOCK | D | 8 250 | ||||||||
| 2014-10-01 | 3 | Hecht Curtis | CALA | COMMON STOCK | D | 8 250 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan | CALA | Common Stock | D | 128 962 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan By Trust | CALA | Common Stock | I | 224 924 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan | CALA | Common Stock | D | 128 962 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan By Trust | CALA | Common Stock | I | 224 924 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Spouse | CALA | Common Stock | I | 128 962 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Trust | CALA | Common Stock | I | 224 924 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Trust | CALA | Common Stock | I | 224 924 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Spouse | CALA | Common Stock | I | 128 962 | ||||||||
| 2014-10-01 | 3 | Bennett Mark K By Trust | CALA | COMMON STOCK | I | 63 108 | ||||||||
| 2014-10-01 | 3 | Bennett Mark K By Trust | CALA | COMMON STOCK | I | 63 108 | ||||||||
| 2014-10-01 | 3 | Sjogren Eric | CALA | COMMON STOCK | D | 23 262 | ||||||||
| 2014-10-01 | 3 | Sjogren Eric | CALA | COMMON STOCK | D | 23 262 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3 567 350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3 567 350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3 567 350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3 567 350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3 567 350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3 567 350 |
P
Köp på öppna marknaden eller privat köp av icke-derivatsäkerhet
S
Köp på öppna marknaden eller privat försäljning av icke-derivatsäkerhet
A
Bevilja, tilldelning eller annat förvärv av värdepapper från företaget (såsom en option)
C
Omvandling av derivat
D
Försäljning eller överföring av värdepapper tillbaka til företaget
F
Betalning av lösenpris eller skatteskuld med del av värdepapper som erhållits från bolaget
G
Överlåtelse av värdepapper från eller till insidern
K
Aktieswappar och liknande säkringsaffärer
M
Utövande eller omvandling av derivatsäkerhet som erhållits från företaget (som en option)
V
En transaktion friviligt rapporterad på schema 4
J
Andra (med en fotnot som beskriver transaktionen)
