| Insideraktier | 10 007 540 shares |
Insider Sentiment Score
Insider sentiment score hittar de företag som köps av foretagsinsynspersoner.
Det är resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av insiderackumulation. Poängmodellen använder en kombination av nettoantalet insiders som köpt de föregående 90 dagarna, det totala antalet aktier som köpts i procent av aktiekapitalet och det totala antalet aktier som ägs av insiders. Siffran sträcker sig från 0 till 100, med högre siffror som indikerar en högre nivå av ackumulering för sina kamrater, och 50 är genomsnittet.
Uppdateringsfrekvens: Dagligen
Se Insiders Top Picks, som ger en lista över företag med högsta insiderackumulation.
Office Sentiment Score
Officersentiment Score hittar företag som köps av Corporate Officers.
Per definition Corporate Officers är Corporate Insiders, men till skillnad från vissa av de andra Insiders (10 % aktieägare och styrelseledamöter), arbetar ämbetsmän för företaget dagligen och de använder sina egna pengar när de handlar . (10 % aktieägare och styrelseledamöter är ofta fondförvaltare som förvaltar andras pengar.) Som sådan är insideraffärer som görs av tjänstemän mycket mer betydelsefulla och bör behandlas på lämpligt sätt.
Liksom Insider Sentiment Score är Officer Sentiment Score resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av officersackumulering.
Uppdateringsfrekvens: Dagligen
Se insiderns bästa val, vilket ger en lista över företag med högsta insider sentiment.
Viktiga insidernyckeltal
Denna kort visar hur företaget rankas längs olika insidernyckeltal. Procenttilrankningen visar hur detta företag jämförs med andra företag på USA-marknaden. Högre rankingar indikerar bättre situationer.
Till exempel anses det allmänt att insiderköp är en positiv indikator, så företag med mer insiderköp skulle rankas högre än företag med mindre insiderköp (eller til och med insiderförsäljning).
Nettoantalet insiders som köper (rankning)
N/A
Nettoantalet insiders som köper är den totala mängden insiders som säljer minus det totala antalet insiders som säljer under de senaste 90 dagarna. Percentilrankningen visas här (intervall från 0 till 100%).
Procent av flytande köpta av insiders (ranking)
N/A
Procentandelen av aktier köpta av insiders är det totala antalet aktier som köpts av insiders minus det totala antalet aktier som sålts av insiders under de senaste 90 dagarna, dividerat med det totala antalet aktier och multiplicerat med 100.
Insiderhandelsdiagram
Alpine Immune Sciences, Inc. insideraffärer visas i följande diagram. Insiders är tjänstemän, styrelseledamöter eller betydande investerare i ett företag. I allmänhet är det i allmänhet olagligt för insiders att göra affärer i sina företag baserat på väsentlig, icke-offentlig information. Detta betyder inte att det är olagligt för dem att göra några affärer i sina egna företag. De måste dock rapportera alla affärer till SEC via ett formulär 4.
Insiderlista och lönsamhetsstatistik
Den här tabellen visar listan över kända insiders och genereras automatiskt från anmälningar som avslöjas till SEC. Förutom namnen, den senaste titeln och direktören, tjänstemannen eller ägarbeteckningen på 10 %, tillhandahåller vi de senaste avslöjade innehaven. Dessutom, när det är möjligt tillhandahåller vi insiderns historiska handelsresultat. Det historiska handelsresultatet är ett vägt genomsnitt av resultatet för faktiska köptransaktioner på den öppna marknaden som insidern gjort. För mer information om hur detta beräknas, titta på detta YouTube-webinarium.
See our leaderboard of most profitable insider traders.
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|
Report errors via our new Insider Auditing Tool
Track Records av insiderköp - Kortsiktig vinstanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i ALPN / Alpine Immune Sciences, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste köpen på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Track Records av insiderförsäljning - Kortsiktig förlustanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i ALPN / Alpine Immune Sciences, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste försäljningarna på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Transaktionshistorik
Klicka på länkikonen för att se hela transaktionshistoriken. Transaktioner som rapporteras som en del av en automatisk handelsplan 10b5-1 kommer att ha ett X i kolumnen markerad 10b-5.
| Fil datum |
Handel datum |
Schema | Insider | Ticker | Värdepappertitel | Kod | Direkta | Utövningspris | Enhet pris |
Enheter ändrad |
Värde ändrad (1K) |
Kvarvarande Optioner |
Kvarvarande Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-05-20 | 2024-05-20 | 4 | Peetz Christopher Christopher Peetz & Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | −1 900 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | −50 000 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | −2 829 347 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | −264 315 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | −2 416 181 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | −1 735 544 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | −6 582 380 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | Rickey James Paul | ALPN | Common Stock | D | −31 200 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | Rickey James Paul | ALPN | Common Stock | D | −26 761 | 31 200 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | PENG STANFORD L | ALPN | Common Stock | D | −48 000 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | PENG STANFORD L | ALPN | Common Stock | D | −296 163 | 48 000 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | −96 000 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | −13 245 | 96 000 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | −2 627 157 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | −7 300 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | −22 820 | 7 300 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | DURAND REMY | ALPN | Common Stock | D | −31 200 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | DURAND REMY | ALPN | Common Stock | D | −102 192 | 31 200 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | −264 315 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | −2 416 181 | 0 | ||||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 6,3300 | 13 377 | 85 | 344 163 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 3,2300 | 26 912 | 87 | 330 786 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 11,3100 | 22 593 | 256 | 303 874 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 0,6500 | 161 492 | 105 | 281 281 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 0,6500 | 37 267 | 24 | 119 789 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 6,5100 | 3 126 | 20 | 82 522 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 13,2000 | 7 025 | 93 | 79 396 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 4,7600 | 10 000 | 48 | 133 392 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 3,2300 | 38 078 | 123 | 123 392 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 4,0900 | 12 365 | 51 | 85 314 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 6,5100 | 25 000 | 163 | 72 949 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 13,2000 | 9 845 | 130 | 47 949 | ||||
| 2024-05-10 | 2024-05-08 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 7,5500 | 13 245 | 100 | 109 245 | ||||
| 2024-05-10 | 2024-05-08 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | 12,0700 | 22 820 | 275 | 30 120 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 398 | 2 | 57 961 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 18 286 | 59 | 57 563 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 11,3100 | 164 | 2 | 39 277 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6,5100 | 857 | 6 | 39 113 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 13,2000 | 7 055 | 93 | 38 256 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 7,5500 | 1 | 0 | 31 201 | ||||
| 2024-04-29 | 2024-04-25 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 64,5700 | −19 | −1 | 2 829 347 | ||||
| 2024-04-29 | 2024-04-25 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 0,0010 | 1 200 000 | 1 | 2 829 366 | ||||
| 2024-04-05 | 3 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | 7 300 | ||||||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 25,0000 | −44 000 | −1 100 | 0 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 11,3100 | 44 000 | 498 | 44 000 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 22,3121 | −73 764 | −1 646 | 0 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6,5100 | 73 764 | 480 | 73 764 | ||||
| 2024-01-29 | 2024-01-25 | 4 | Rickey James Paul | ALPN | Common Stock | D | 22,0000 | −236 | −5 | 0 | ||||
| 2024-01-29 | 2024-01-25 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6,5100 | 236 | 2 | 236 | ||||
| 2024-01-22 | 2024-01-18 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 12,7400 | 1 234 636 | 15 729 | 6 582 380 | ||||
| 2024-01-22 | 2024-01-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 12,7400 | 1 234 636 | 15 729 | 6 582 380 | ||||
| 2024-01-16 | 2024-01-11 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 12,7400 | 145 251 | 1 850 | 2 416 181 | ||||
| 2024-01-16 | 2024-01-11 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 12,7400 | 145 251 | 1 850 | 2 416 181 | ||||
| 2024-01-05 | 2024-01-04 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 48 000 | 72 371 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 96 000 | 96 000 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 31 200 | 31 200 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | DURAND REMY | ALPN | Common Stock | D | 31 200 | 38 104 | ||||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 19,6500 | −48 264 | −948 | 2 627 157 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 12,7400 | 74 441 | 948 | 2 675 421 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,0413 | −1 016 | −20 | 0 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,6500 | 1 016 | 1 | 1 016 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 18,3200 | −139 166 | −2 550 | 264 315 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 18,3200 | −1 195 683 | −21 905 | 2 270 930 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,8200 | −3 128 | −62 | 403 481 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,8200 | −26 872 | −533 | 3 466 613 | ||||
| 2023-12-29 | 2023-12-27 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,9600 | −18 922 | −378 | 406 609 | ||||
| 2023-12-29 | 2023-12-27 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,9600 | −162 576 | −3 245 | 3 493 485 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 18,3200 | −139 166 | −2 550 | 264 315 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 18,3200 | −1 195 683 | −21 905 | 2 270 930 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,8200 | −3 128 | −62 | 403 481 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,8200 | −26 872 | −533 | 3 466 613 | ||||
| 2023-12-29 | 2023-12-27 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,9600 | −18 922 | −378 | 406 609 | ||||
| 2023-12-29 | 2023-12-27 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,9600 | −162 576 | −3 245 | 3 493 485 | ||||
| 2023-12-27 | 2023-12-27 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,0425 | −29 573 | −593 | 0 | ||||
| 2023-12-27 | 2023-12-27 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,6500 | 29 573 | 19 | 29 573 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,2245 | −24 486 | −495 | 0 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,6500 | 22 084 | 14 | 24 486 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 2 402 | 1 | 2 402 | ||||
| 2023-12-27 | 2023-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,4255 | −37 825 | −773 | 0 | ||||
| 2023-12-27 | 2023-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 37 825 | 17 | 37 825 | ||||
| 2023-12-21 | 2023-12-19 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,2087 | −15 213 | −292 | 0 | ||||
| 2023-12-21 | 2023-12-19 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 15 213 | 76 | 15 213 | ||||
| 2023-12-21 | 2023-12-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,0099 | −2 402 | −48 | 0 | ||||
| 2023-12-21 | 2023-12-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 2 402 | 1 | 2 402 | ||||
| 2023-12-18 | 2023-12-18 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,0017 | −1 800 | −34 | 0 | ||||
| 2023-12-18 | 2023-12-18 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 1 800 | 9 | 1 800 | ||||
| 2023-12-18 | 2023-12-15 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,0888 | −45 387 | −866 | 0 | ||||
| 2023-12-18 | 2023-12-15 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 45 387 | 228 | 45 387 | ||||
| 2023-12-18 | 2023-12-14 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,0005 | −11 600 | −220 | 0 | ||||
| 2023-12-18 | 2023-12-14 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 11 600 | 58 | 11 600 | ||||
| 2023-12-13 | 2023-12-11 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 12,7400 | 145 251 | 1 850 | 1 629 366 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,3155 | −8 613 | −149 | 0 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 8 613 | 4 | 8 613 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,3155 | −32 450 | −562 | 0 | ||||
| 2023-12-12 | 2023-12-11 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,2648 | −68 870 | −1 189 | 32 450 | ||||
| 2023-12-12 | 2023-12-08 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,0799 | −8 067 | −138 | 101 320 | ||||
| 2023-12-06 | 2023-12-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0797 | −6 446 | −104 | 0 | ||||
| 2023-12-06 | 2023-12-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 6 446 | 21 | 6 446 | ||||
| 2023-12-06 | 2023-12-05 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0139 | −418 | −7 | 0 | ||||
| 2023-12-06 | 2023-12-05 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 418 | 1 | 418 | ||||
| 2023-12-06 | 2023-12-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0584 | −63 947 | −1 027 | 0 | ||||
| 2023-12-06 | 2023-12-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 63 947 | 207 | 63 947 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0000 | −700 | −11 | 0 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 700 | 2 | 700 | ||||
| 2023-11-14 | 2023-11-09 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 12,5000 | 375 000 | 4 688 | 1 735 544 | ||||
| 2023-11-14 | 2023-11-09 | 4 | Decheng Capital Global Healthcare Fund (Master), LP | ALPN | Common Stock | D | 12,5000 | 375 000 | 4 688 | 1 735 544 | ||||
| 2023-11-08 | 2023-11-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0281 | −18 003 | −289 | 0 | ||||
| 2023-11-08 | 2023-11-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 10 989 | 35 | 18 003 | ||||
| 2023-04-27 | 3 | DURAND REMY | ALPN | Common Stock | D | 6 904 | ||||||||
| 2022-09-27 | 2022-09-23 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 7,3500 | 1 360 544 | 10 000 | 1 360 544 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 7,3500 | 639 456 | 4 700 | 5 347 744 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | I | 7,3500 | 1 360 544 | 10 000 | 1 360 544 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 7,3500 | 639 456 | 4 700 | 5 347 744 | ||||
| 2022-07-19 | 2022-07-15 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 0,4500 | 20 063 | 9 | 238 126 | ||||
| 2022-02-15 | 2022-02-11 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 7,1006 | 112 665 | 800 | 1 484 115 | ||||
| 2022-01-06 | 2022-01-04 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 13,30 | 215 000 | 215 000 | |||||
| 2022-01-06 | 2022-01-04 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 13,30 | 215 000 | 215 000 | |||||
| 2022-01-06 | 2022-01-04 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 13,30 | 112 500 | 112 500 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Hernday Natasha | ALPN | Stock Option (Right to buy) | D | 13,89 | 10 000 | 10 000 | |||||
| 2022-01-04 | 2021-12-31 | 4 | Rickey James Paul | ALPN | Common Stock | D | 13,9162 | −17 013 | −237 | 7 014 | ||||
| 2022-01-04 | 2022-01-03 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 13,89 | 10 000 | 10 000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 13,89 | 10 000 | 10 000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 13,89 | 10 000 | 10 000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 13,89 | 10 000 | 10 000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 13,89 | 10 000 | 10 000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 13,89 | 10 000 | 10 000 | |||||
| 2021-09-27 | 2021-09-23 | 4/A | Peetz Christopher Christopher Peetz and Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | 10,1700 | 1 900 | 19 | 1 900 | ||||
| 2021-09-27 | 2021-09-23 | 4/A | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 10,0769 | 15 000 | 151 | 50 000 | ||||
| 2021-09-24 | 2021-09-23 | 4 | Peetz Christopher Christopher Peetz & Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | 10,1700 | 1 900 | 19 | 1 900 | ||||
| 2021-09-24 | 2021-09-23 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 10,0769 | 15 000 | 151 | 50 000 | ||||
| 2021-09-23 | 2021-09-21 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 9,7966 | 10 000 | 98 | 35 000 | ||||
| 2021-09-21 | 2021-09-17 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 9,4000 | 425 531 | 4 000 | 425 531 | ||||
| 2021-09-21 | 2021-09-17 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 9,4000 | 585 106 | 5 500 | 3 656 061 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 9,4000 | 1 542 553 | 14 500 | 4 708 288 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 9,4000 | 425 531 | 4 000 | 425 531 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 9,4000 | 585 106 | 5 500 | 3 656 061 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 9,4000 | −400 000 | −3 760 | 2 600 980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0076 | −45 262 | −453 | 109 387 | ||||
| 2021-09-21 | 2021-09-17 | 4 | GOLD MITCHELL By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 9,4000 | −400 000 | −3 760 | 2 600 980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Venkatesan Jay By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 9,4000 | −400 000 | −3 760 | 2 600 980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 9,4000 | 1 542 553 | 14 500 | 4 708 288 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | D | 0,00 | 1 200 000 | 1 200 000 | |||||
| 2021-09-21 | 2021-09-17 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | −1 200 000 | 1 371 450 | ||||||
| 2021-09-17 | 2021-09-16 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0024 | −6 768 | −68 | 154 649 | ||||
| 2021-09-17 | 2021-09-15 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0000 | −3 484 | −35 | 161 417 | ||||
| 2021-06-29 | 2021-06-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0005 | −3 479 | −35 | 164 901 | ||||
| 2021-06-29 | 2021-06-25 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0143 | −9 473 | −95 | 168 380 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Goldberg Zelanna | ALPN | Stock Option (Right to buy) | D | 10,29 | 160 000 | 160 000 | |||||
| 2021-05-21 | 2021-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 15,0006 | −1 221 | −18 | 177 853 | ||||
| 2021-05-21 | 2021-05-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 15,0283 | −50 965 | −766 | 179 074 | ||||
| 2021-05-14 | 2021-05-13 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11,5169 | −10 000 | −115 | 230 039 | ||||
| 2021-05-14 | 2021-05-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11,6842 | −10 000 | −117 | 240 039 | ||||
| 2021-04-23 | 2021-03-31 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 3,62 | −7 650 | 0 | |||||
| 2021-04-23 | 2021-03-31 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 3,6233 | 7 650 | 28 | 218 063 | ||||
| 2021-04-23 | 2021-03-30 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 4,09 | −7 650 | 0 | |||||
| 2021-04-23 | 2021-03-30 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 4,0900 | 7 650 | 31 | 210 413 | ||||
| 2021-04-15 | 2021-04-14 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,5200 | −10 000 | −105 | 250 039 | ||||
| 2021-04-15 | 2021-04-13 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0714 | −10 000 | −101 | 260 039 | ||||
| 2021-03-08 | 2021-03-05 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12,9875 | −10 000 | −130 | 270 039 | ||||
| 2021-03-08 | 2021-03-04 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 13,0108 | −10 000 | −130 | 280 039 | ||||
| 2021-02-03 | 2021-02-02 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11,7381 | −10 000 | −117 | 290 039 | ||||
| 2021-02-03 | 2021-02-01 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 13,2029 | −7 021 | −93 | 300 039 | ||||
| 2021-02-03 | 2021-02-01 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12,0738 | −2 979 | −36 | 307 060 | ||||
| 2021-01-06 | 2021-01-05 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 13,20 | 150 000 | 150 000 | |||||
| 2021-01-06 | 2021-01-05 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 13,20 | 255 000 | 255 000 | |||||
| 2021-01-06 | 2021-01-05 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 13,20 | 120 000 | 120 000 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Hernday Natasha | ALPN | Stock Option (Right to buy) | D | 13,45 | 7 650 | 7 650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 13,45 | 7 650 | 7 650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 13,45 | 7 650 | 7 650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 13,45 | 7 650 | 7 650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 13,45 | 7 650 | 7 650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 13,45 | 7 650 | 7 650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 13,45 | 7 650 | 7 650 | |||||
| 2021-01-04 | 2020-12-31 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 12,6000 | −3 923 | −49 | 24 371 | ||||
| 2021-01-04 | 2020-12-31 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12,6000 | −11 123 | −140 | 310 039 | ||||
| 2021-01-04 | 2020-12-31 | 4 | Rickey James Paul | ALPN | Common Stock | D | 12,6000 | −2 258 | −28 | 24 027 | ||||
| 2020-12-30 | 2020-12-28 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 14,2500 | −600 000 | −8 550 | 3 070 955 | ||||
| 2020-12-30 | 2020-12-28 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 14,2500 | −600 000 | −8 550 | 3 070 955 | ||||
| 2020-12-22 | 2020-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 260 528 | 321 162 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | GOLD MITCHELL By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | −993 801 | 3 000 980 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 181 024 | 202 763 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Venkatesan Jay By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | −993 801 | 3 000 980 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | −993 801 | 3 000 980 | ||||||
| 2020-12-11 | 2020-12-10 | 4 | Hernday Natasha | ALPN | Stock Option (right to buy) | D | 11,07 | 15 000 | 15 000 | |||||
| 2020-11-23 | 2020-11-19 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 8,0300 | 10 000 | 80 | 25 000 | ||||
| 2020-07-09 | 2020-07-08 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 7,20 | 50 000 | 50 000 | |||||
| 2020-07-01 | 2020-06-30 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 9,7100 | −3 923 | −38 | 28 294 | ||||
| 2020-07-01 | 2020-06-30 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 9,7100 | −8 227 | −80 | 60 634 | ||||
| 2020-07-01 | 2020-06-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 9,7100 | −2 258 | −22 | 26 285 | ||||
| 2020-01-27 | 2020-01-23 | 4 | GOLD MITCHELL | ALPN | Stock Option (right to buy) | D | 3,23 | 270 000 | 270 000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 67 569 | 68 861 | ||||||
| 2020-01-27 | 2019-12-23 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | −5 000 | 1 292 | ||||||
| 2020-01-27 | 2019-12-11 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | −5 000 | 6 292 | ||||||
| 2020-01-27 | 2020-01-23 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 3,23 | 108 000 | 108 000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 32 217 | 32 217 | ||||||
| 2020-01-27 | 2020-01-23 | 4 | Rickey James Paul | ALPN | Stock Option (right to buy) | D | 3,23 | 102 000 | 102 000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | Rickey James Paul | ALPN | Common Stock | D | 18 543 | 28 543 | ||||||
| 2020-01-06 | 2020-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 3,62 | 7 650 | 7 650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 3,62 | 7 650 | 7 650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 3,62 | 7 650 | 7 650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 3,62 | 7 650 | 7 650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 3,62 | 7 650 | 7 650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 3,62 | 7 650 | 7 650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 3,62 | 7 650 | 7 650 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 4,9500 | 10 000 | 50 | 10 000 | ||||
| 2019-02-12 | 2019-02-08 | 4 | TIGER MANAGEMENT L.L.C. | ALPN | Common Stock | I | 5,8498 | −25 000 | −146 | 137 728 | ||||
| 2019-02-08 | 2019-02-06 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 6,51 | 75 000 | 75 000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6,51 | 75 000 | 75 000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6,81 | 25 000 | 25 000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | GOLD MITCHELL | ALPN | Stock Option (right to buy) | D | 6,51 | 200 000 | 200 000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Rickey James Paul | ALPN | Stock Option (right to buy) | D | 6,51 | 75 000 | 75 000 | |||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6 331 470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6 331 470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6 331 470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6 331 470 | ||||||||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Stock Option (right to buy) | D | 5,70 | 7 650 | 7 650 | |||||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Warrant (right to buy) | I | 12,74 | 5,3700 | 1 234 636 | 6 630 | 1 234 636 | |||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 5,3700 | 3 165 735 | 17 000 | 3 165 735 | ||||
| 2019-01-23 | 2019-01-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Warrants to Purchase Common Stock | I | 145 251 | 145 251 | ||||||
| 2019-01-23 | 2019-01-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 5,3700 | 372 439 | 2 000 | 3 670 955 | ||||
| 2019-01-23 | 2019-01-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Warrants to Purchase Common Stock | I | 145 251 | 145 251 | ||||||
| 2019-01-23 | 2019-01-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 5,3700 | 372 439 | 2 000 | 3 670 955 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Venkatesan Jay Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | I | 12,74 | 74 441 | 74 441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Venkatesan Jay Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 5,3700 | 190 875 | 1 025 | 3 994 781 | ||||
| 2019-01-22 | 2019-01-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | I | 12,74 | 74 441 | 74 441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 5,3700 | 190 875 | 1 025 | 3 994 781 | ||||
| 2019-01-22 | 2018-05-21 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | −6 000 | 11 292 | ||||||
| 2019-01-22 | 2018-05-15 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | −3 000 | 17 292 | ||||||
| 2019-01-22 | 2018-05-14 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | −3 000 | 20 292 | ||||||
| 2019-01-22 | 2019-01-18 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | D | 12,74 | 74 441 | 74 441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 5,3700 | 190 875 | 1 025 | 3 994 781 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | I | 12,74 | 145 251 | 145 251 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 5,3700 | 372 439 | 2 000 | 2 571 450 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | D | 12,74 | 145 251 | 145 251 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 5,3700 | 372 439 | 2 000 | 2 571 450 | ||||
| 2019-01-04 | 2019-01-02 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 4,09 | 7 650 | 7 650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 4,09 | 7 650 | 7 650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 4,09 | 7 650 | 7 650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 4,09 | 7 650 | 7 650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 4,09 | 7 650 | 7 650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 4,09 | 7 650 | 7 650 | |||||
| 2018-10-02 | 2018-09-28 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 6,33 | 250 000 | 250 000 | |||||
| 2018-08-08 | 2018-08-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6,81 | 150 000 | 150 000 | |||||
| 2018-04-24 | 2018-04-20 | 4 | Peetz Christopher | ALPN | Stock Option (right to buy) | D | 7,91 | 7 650 | 7 650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 11,31 | 70 000 | 70 000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 11,31 | 45 000 | 45 000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 11,31 | 7 650 | 7 650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 11,31 | 7 650 | 7 650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 11,31 | 7 650 | 7 650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 11,31 | 65 000 | 65 000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 11,31 | 25 000 | 25 000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 11,31 | 7 650 | 7 650 | |||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4 398 022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4 398 022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4 398 022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4 398 022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4 398 022 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7 607 812 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7 607 812 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7 607 812 | ||||||||
| 2017-07-26 | 2017-07-24 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 3 298 516 | 3 298 516 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 5,02 | 208 916 | 208 916 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 0,65 | 300 624 | 300 624 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 0,45 | 51 242 | 51 242 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL Alpine Immunosciences, L.P. | ALPN | Common Stock | I | 3 803 906 | 3 803 906 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 23 292 | 23 292 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Aidan J. Gold | ALPN | Common Stock | I | 24 845 | 24 845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Simon P. Gold | ALPN | Common Stock | I | 24 845 | 24 845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Noah M. Gold | ALPN | Common Stock | I | 24 845 | 24 845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay | ALPN | Employee Stock Option (right to buy) | D | 0,45 | 90 063 | 90 063 | |||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay Alpine Immunosciences, L.P. | ALPN | Common Stock | I | 3 803 906 | 3 803 906 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 21 739 | 21 739 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay By Raj Venkatesan as UTMA custodian for Nathaniel Graham Venkatesan | ALPN | Common Stock | I | 18 633 | 18 633 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay By Raj Venkatesan as UTMA custodian for Reid Coleman Venkatesan | ALPN | Common Stock | I | 18 633 | 18 633 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Rickey James Paul | ALPN | Employee Stock Option (right to buy) | D | 5,02 | 74 535 | 74 535 | |||||
| 2017-07-26 | 2017-07-24 | 4 | Topper James N See Footnotes | ALPN | Common Stock | I | 2 199 011 | 2 199 011 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 3 298 516 | 3 298 516 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | PENG STANFORD L | ALPN | Employee Stock Option (right to buy) | D | 0,65 | 37 267 | 37 267 | |||||
| 2017-07-26 | 2017-07-24 | 4 | PENG STANFORD L | ALPN | Employee Stock Option (right to buy) | D | 0,65 | 161 492 | 161 492 | |||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2500 | 1 715 | 4 | 201 811 | ||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2500 | 6 359 | 14 | 717 089 | ||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2500 | 9 732 | 22 | 1 109 258 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2813 | 3 673 | 8 | 200 096 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2813 | 13 046 | 30 | 710 730 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2813 | 20 181 | 46 | 1 099 526 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2906 | 3 920 | 9 | 196 423 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2906 | 12 624 | 29 | 697 684 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2906 | 19 206 | 44 | 1 079 345 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2470 | 2 727 | 6 | 192 503 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2470 | 10 023 | 23 | 685 060 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2470 | 15 350 | 34 | 1 060 139 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2957 | 1 805 | 4 | 189 776 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2957 | 6 903 | 16 | 675 037 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2957 | 10 192 | 23 | 1 044 789 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3000 | 1 124 | 3 | 187 971 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3000 | 4 223 | 10 | 668 134 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3000 | 6 253 | 14 | 1 034 597 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2998 | 2 909 | 7 | 186 847 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2998 | 10 541 | 24 | 663 911 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2998 | 16 436 | 38 | 1 028 344 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2987 | 5 510 | 13 | 183 938 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2987 | 6 897 | 16 | 653 370 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2987 | 24 965 | 57 | 1 011 908 | ||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1 870 417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 630 471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 310 352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 630 471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 310 352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1 870 417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 630 471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 310 352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1 870 417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 630 471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 310 352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1 870 417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 630 471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 310 352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1 870 417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 630 471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 310 352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1 870 417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 630 471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 310 352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1 870 417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 630 471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2 310 352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1 870 417 | ||||||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3429 | 675 | 2 | 178 428 | ||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3429 | 2 565 | 6 | 646 473 | ||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3429 | 3 794 | 9 | 986 943 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3457 | 6 217 | 15 | 177 753 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3457 | 22 092 | 52 | 643 908 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3457 | 33 691 | 79 | 983 149 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2879 | 3 929 | 9 | 171 536 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2879 | 14 274 | 33 | 621 816 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2879 | 21 797 | 50 | 949 458 | ||||
| 2017-05-11 | 2017-05-08 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,2800 | 15 000 | 34 | 60 000 | ||||
| 2017-05-10 | 2017-05-09 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,3400 | 5 000 | 12 | 45 000 | ||||
| 2017-05-09 | 2017-05-05 | 4 | TROHA JANICE | NVLS | Common Stock | D | 2,3400 | 10 000 | 23 | 10 000 | ||||
| 2017-05-09 | 2017-05-05 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,3000 | 20 000 | 46 | 40 000 | ||||
| 2017-05-08 | 2017-05-04 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,2600 | 10 000 | 23 | 20 000 | ||||
| 2017-01-23 | 2017-01-12 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 2,21 | 200 000 | 200 000 | |||||
| 2017-01-23 | 2017-01-12 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 2,21 | 200 000 | 200 000 | |||||
| 2017-01-05 | 2017-01-04 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 2,2700 | −6 687 | −15 | 11 368 | ||||
| 2017-01-05 | 2017-01-03 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0,00 | −18 056 | 162 501 | |||||
| 2017-01-05 | 2017-01-03 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18 055 | 18 055 | ||||||
| 2016-12-05 | 2016-12-02 | 4 | Carruthers R Michael | NVLS | Common Stock | D | 2,0940 | 24 000 | 50 | 24 000 | ||||
| 2016-10-05 | 2016-10-04 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 7,9600 | −5 820 | −46 | 12 236 | ||||
| 2016-10-05 | 2016-10-03 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0,00 | −18 056 | 180 556 | |||||
| 2016-10-05 | 2016-10-03 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18 056 | 18 056 | ||||||
| 2016-09-14 | 2016-09-12 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12 300 | 12 300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12 300 | 12 300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Loh Evan | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12 300 | 12 300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | MOORE JOHN R | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12 300 | 12 300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 7,77 | 110 000 | 110 000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | SEKHRI PAUL J | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12 300 | 12 300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Flynn James E Through Deerfield Management Company, L.P. | NVLS | Stock Option (right to buy) | I | 7,77 | 12 300 | 12 300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 7,77 | 110 000 | 110 000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Congleton Jon | NVLS | Stock Option (Right to Buy) | D | 7,77 | 250 000 | 250 000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Rodman David Malcom | NVLS | Stock Option (Right to Buy) | D | 7,77 | 100 000 | 100 000 | |||||
| 2016-07-06 | 2016-07-05 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 4,6600 | −5 950 | −28 | 12 105 | ||||
| 2016-07-06 | 2016-07-01 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0,00 | −18 055 | 198 612 | |||||
| 2016-07-06 | 2016-07-01 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18 055 | 18 055 | ||||||
| 2016-06-17 | 2016-06-16 | 4 | Congleton Jon | NVLS | Common Stock | D | 3,8689 | 5 000 | 19 | 20 000 | ||||
| 2016-03-25 | 2016-03-24 | 4 | Congleton Jon | NVLS | Common Stock | D | 4,2169 | 5 000 | 21 | 15 000 | ||||
| 2016-03-23 | 2016-03-22 | 4 | Congleton Jon | NVLS | Common Stock | D | 4,3815 | 5 000 | 22 | 10 000 | ||||
| 2015-12-14 | 2015-12-11 | 4 | Congleton Jon | NVLS | Common Stock | D | 8,1000 | 5 000 | 40 | 5 000 | ||||
| 2015-12-11 | 2015-12-09 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 8,1000 | 10 000 | 81 | 10 000 | ||||
| 2015-09-15 | 2015-09-11 | 4 | Shoemaker Steven | NVLS | Stock Option (Right to Buy) | D | 15,28 | 39 700 | 39 700 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 15,28 | 55 400 | 55 400 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Gabriel Sherif | NVLS | Stock Option (Right to Buy) | D | 15,28 | 24 700 | 24 700 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Congleton Jon | NVLS | Stock Option (Right to Buy) | D | 15,28 | 121 100 | 121 100 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Loh Evan | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7 650 | 7 650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7 650 | 7 650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | LEFF JONATHAN S | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7 650 | 7 650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 15,28 | 65 400 | 65 400 | |||||
| 2015-09-15 | 2015-09-11 | 4 | MOORE JOHN R | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7 650 | 7 650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7 650 | 7 650 | |||||
| 2015-07-20 | 2015-07-16 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 17,49 | 11 475 | 11 475 | |||||
| 2015-07-20 | 2015-07-16 | 4 | LEFF JONATHAN S | NVLS | Stock Option (Right to Buy) | D | 17,49 | 11 475 | 11 475 | |||||
| 2015-07-20 | 2015-07-16 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 17,49 | 11 475 | 11 475 | |||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Series 2 Preferred Stock | I | −936 839 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Series 2 Preferred Stock | I | −817 541 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Series 2 Preferred Stock | I | −85 962 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Series 2 Preferred Stock | I | −54 385 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Series 2 Preferred Stock | I | −385 962 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Series 1 Preferred Stock | I | −1 243 423 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Series 1 Preferred Stock | I | −1 085 085 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Series 1 Preferred Stock | I | −1 401 003 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Series 1 Preferred Stock | I | −869 667 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Series 1 Preferred Stock | I | −2 013 613 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 14,0000 | 77 539 | 1 086 | 832 216 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 14,0000 | 67 666 | 947 | 726 242 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 14,0000 | 104 795 | 1 467 | 1 124 740 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 324 278 | 754 677 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 282 984 | 658 576 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 29 755 | 647 152 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 18 825 | 402 062 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 133 597 | 1 019 945 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 430 399 | 430 399 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 375 592 | 375 592 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 484 944 | 617 397 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 301 027 | 383 237 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 696 993 | 886 348 | ||||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Series 2 Convertible Preferred Stock | I | 2,85 | −364 358 | 0 | |||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Common Stock | I | 14,0000 | 200 000 | 2 800 | 564 358 | ||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Common Stock | I | 364 358 | 364 358 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | NVLS | Series 2 convertible preferred stock | D | −1 052 631 | 0 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | NVLS | Common stock | D | 364 358 | 364 358 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Series 2 convertible preferred stock | D | −818 714 | 0 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 283 390 | 320 990 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,7479 | 5 500 | 81 | 37 600 | ||||
| 2015-06-23 | 2015-06-19 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,6659 | 11 700 | 172 | 32 100 | ||||
| 2015-06-22 | 2015-06-22 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Series 2 convertible preferred stock | D | 14,00 | −303 631 | 0 | |||||
| 2015-06-22 | 2015-06-22 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Common Stock | D | 14,0000 | 303 631 | 4 251 | 329 780 | ||||
| 2015-06-22 | 2015-06-22 | 4 | Estate of Arnold H. Snider, III | NVLS | Series 1 convertible preferred stock | D | −2 200 404 | 0 | ||||||
| 2015-06-22 | 2015-06-22 | 4 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 761 649 | 1 557 228 | ||||||
| 2015-06-19 | 2015-06-18 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,7500 | 6 200 | 91 | 20 400 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,7500 | 6 700 | 99 | 14 200 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,0000 | 7 500 | 105 | 7 500 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Common Stock | D | 14,0000 | 26 149 | 366 | 26 149 | ||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1 301 830 | ||||||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1 301 830 | ||||||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1 301 830 | ||||||||
| 2015-06-17 | 3 | TIGER MANAGEMENT L.L.C. | NVLS | Common Stock | I | 1 301 830 | ||||||||
| 2015-06-17 | 3 | TIGER MANAGEMENT L.L.C. | NVLS | Common Stock | I | 1 301 830 | ||||||||
| 2015-06-17 | 3 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 1 591 158 | ||||||||
| 2015-06-17 | 3 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 1 591 158 | ||||||||
| 2015-06-16 | 3 | Loh Evan | NVLS | Common Stock | D | 4 326 | ||||||||
| 2015-06-16 | 3 | Loh Evan | NVLS | Common Stock | D | 4 326 | ||||||||
| 2015-06-16 | 3 | TROHA JANICE | NVLS | Common Stock | D | 66 558 | ||||||||
| 2015-06-16 | 3 | TROHA JANICE | NVLS | Common Stock | D | 66 558 | ||||||||
| 2015-06-16 | 3 | MOORE JOHN R | NVLS | Common Stock | D | 4 326 | ||||||||
| 2015-06-16 | 3 | MOORE JOHN R | NVLS | Common Stock | D | 4 326 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486 233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536 475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593 380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486 233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536 475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593 380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593 380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486 233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593 380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486 233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593 380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536 475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593 380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536 475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486 233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593 380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536 475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486 233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536 475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536 475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486 233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593 380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486 233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486 233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536 475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593 380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536 475 |
P
Köp på öppna marknaden eller privat köp av icke-derivatsäkerhet
S
Köp på öppna marknaden eller privat försäljning av icke-derivatsäkerhet
A
Bevilja, tilldelning eller annat förvärv av värdepapper från företaget (såsom en option)
C
Omvandling av derivat
D
Försäljning eller överföring av värdepapper tillbaka til företaget
F
Betalning av lösenpris eller skatteskuld med del av värdepapper som erhållits från bolaget
G
Överlåtelse av värdepapper från eller till insidern
K
Aktieswappar och liknande säkringsaffärer
M
Utövande eller omvandling av derivatsäkerhet som erhållits från företaget (som en option)
V
En transaktion friviligt rapporterad på schema 4
J
Andra (med en fotnot som beskriver transaktionen)
