| Utestående aktier | 20,984,161 shares |
| Insideraktier | 12 449 629 shares |
| Insynsägande | 59,33 % |
| Totalt antal insynspersoner | 74 |
Insider Sentiment Score
Insider sentiment score hittar de företag som köps av foretagsinsynspersoner.
Det är resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av insiderackumulation. Poängmodellen använder en kombination av nettoantalet insiders som köpt de föregående 90 dagarna, det totala antalet aktier som köpts i procent av aktiekapitalet och det totala antalet aktier som ägs av insiders. Siffran sträcker sig från 0 till 100, med högre siffror som indikerar en högre nivå av ackumulering för sina kamrater, och 50 är genomsnittet.
Uppdateringsfrekvens: Dagligen
Se Insiders Top Picks, som ger en lista över företag med högsta insiderackumulation.
Office Sentiment Score
Officersentiment Score hittar företag som köps av Corporate Officers.
Per definition Corporate Officers är Corporate Insiders, men till skillnad från vissa av de andra Insiders (10 % aktieägare och styrelseledamöter), arbetar ämbetsmän för företaget dagligen och de använder sina egna pengar när de handlar . (10 % aktieägare och styrelseledamöter är ofta fondförvaltare som förvaltar andras pengar.) Som sådan är insideraffärer som görs av tjänstemän mycket mer betydelsefulla och bör behandlas på lämpligt sätt.
Liksom Insider Sentiment Score är Officer Sentiment Score resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av officersackumulering.
Uppdateringsfrekvens: Dagligen
Se insiderns bästa val, vilket ger en lista över företag med högsta insider sentiment.
Viktiga insidernyckeltal
Denna kort visar hur företaget rankas längs olika insidernyckeltal. Procenttilrankningen visar hur detta företag jämförs med andra företag på USA-marknaden. Högre rankingar indikerar bättre situationer.
Till exempel anses det allmänt att insiderköp är en positiv indikator, så företag med mer insiderköp skulle rankas högre än företag med mindre insiderköp (eller til och med insiderförsäljning).
Procent av flytande köpta av insiders (ranking)
0.000 %( )
5027 out of 11219Procentandelen av aktier köpta av insiders är det totala antalet aktier som köpts av insiders minus det totala antalet aktier som sålts av insiders under de senaste 90 dagarna, dividerat med det totala antalet aktier och multiplicerat med 100.
Insiderhandelsdiagram
Adverum Biotechnologies, Inc. insideraffärer visas i följande diagram. Insiders är tjänstemän, styrelseledamöter eller betydande investerare i ett företag. I allmänhet är det i allmänhet olagligt för insiders att göra affärer i sina företag baserat på väsentlig, icke-offentlig information. Detta betyder inte att det är olagligt för dem att göra några affärer i sina egna företag. De måste dock rapportera alla affärer till SEC via ett formulär 4.
Insiderlista och lönsamhetsstatistik
Den här tabellen visar listan över kända insiders och genereras automatiskt från anmälningar som avslöjas till SEC. Förutom namnen, den senaste titeln och direktören, tjänstemannen eller ägarbeteckningen på 10 %, tillhandahåller vi de senaste avslöjade innehaven. Dessutom, när det är möjligt tillhandahåller vi insiderns historiska handelsresultat. Det historiska handelsresultatet är ett vägt genomsnitt av resultatet för faktiska köptransaktioner på den öppna marknaden som insidern gjort. För mer information om hur detta beräknas, titta på detta YouTube-webinarium.
See our leaderboard of most profitable insider traders.
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
| Linda Bain Chief Financial Officer - [O] | 41 930 | 41 930 | |
| Barone Samuel B. SVP, Clinical Development - [O] | 172 335 | 17 234 | |
| Richard Beckman Chief Medical Officer - [O] | 43 333 | 4 333 | |
| Blumenkranz Mark S. Director - [D] | 531 322 | 531 322 | |
| Shirley Braun VP, Human Resources - [O] | 161 140 | 161 140 | |
| Eric G Carter Director - [D] | 48 000 | 4 800 | |
| Chalberg Thomas W. Chief Executive Officer, Director - [D] [O] | 258 988 | 258 988 | |
| Cheng Jennifer C. General Counsel - [O] | 118 863 | 11 886 | |
| Julie Clark Chief Medical Officer - [O] | 164 723 | 16 472 | |
| Paul B Cleveland Chief Executive Officer, Director - [D] [O] | 22 727 | 2 273 | |
| Athena Countouriotis SVP, Chief Medical Officer - [O] | 150 000 | 15 000 | |
| Rupert D'Souza Chief Financial Officer - [O] | 20 850 | 2 085 | |
|
Management Co Deerfield
10% Owner -
|
627 267 | 627 267 | |
|
Deerfield Partners, L.p.
10% Owner -
|
627 267 | 627 267 | |
|
Deerfield International Master Fund, L.P.
10% Owner -
|
627 267 | 627 267 | |
|
Deerfield Mgmt III, L.P.
10% Owner -
|
627 267 | 627 267 | |
|
Deerfield Mgmt L.P.
10% Owner -
|
627 267 | 627 267 | |
|
Deerfield Private Design Fund III, L.P.
10% Owner -
|
627 267 | 627 267 | |
|
Deerfield Special Situations Fund, L.P.
10% Owner -
|
627 267 | 627 267 | |
|
Deerfield Special Situations International Master Fund, L.P.
10% Owner -
|
627 267 | 627 267 | |
| Finer Mitchell H. Director - [D] | 603 069 | 60 307 | |
| Laurent Fischer CEO, PRESIDENT AND DIRECTOR, Director - [D] [O] | 87 488 | 87 488 | |
|
James E Flynn
10% Owner -
|
627 267 | 627 267 | |
| Mehdi Gasmi Director - [D] | 274 442 | 27 444 |
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
| Rekha Hemrajani Director - [D] | 0 | 0 | |
| Soo Hong Director - [D] | 0 | 0 | |
|
Anders D Hove
10% Owner -
|
2 365 471 | 2 365 471 | |
| Hans Hull Chief Executive Officer - [O] | 137 210 | 137 210 | |
|
Bong Y Koh
10% Owner -
|
2 365 471 | 2 365 471 | |
|
Braden Michael Leonard
10% Owner -
|
141 800 | 141 800 | |
| Thomas Leung Chief Financial Officer - [O] | 0 | 0 | |
| Lupher, Jr. Mark L. Director - [D] | 130 000 | 13 000 | |
| John Peter Mclaughlin Director - [D] | 10 333 | 10 333 | |
| Patrick Machado Director - [D] | 88 182 | 8 818 | |
| Nicholson, C. David Director - [D] | 0 | 0 | |
| Aaron Osborne Chief Medical Officer - [O] | 0 | 0 | |
| Rabia Gurses Ozden Chief Medical Officer - [O] | 8 125 | 8 125 | |
| Leone D Patterson President and CFO - [O] | 97 955 | 9 796 | |
| Nancy E Pecota Principal Accounting Officer - [O] | 0 | 0 | |
|
Regeneron Pharmaceuticals Inc
10% Owner -
|
1 809 098 | 1 809 098 | |
| John Rakow SVP, Genl Counsel, Acting CFO - [O] | 58 233 | 5 823 | |
| Brigit Riley Chief Scientific Officer - [O] | 117 435 | 11 744 | |
| Linda M Rubinstein CHIEF FINANCIAL OFFICER - [O] | 19 325 | 19 325 | |
| Rubio Roman G. SVP, Translational Medicine - [O] | 165 650 | 165 650 | |
| Carlo Russo | 66 000 | ||
| Amber Salzman President and CEO, Director - [D] [O] | 891 766 | 89 177 | |
| Steven Daniel Schwartz Director - [D] | 398 991 | 39 899 | |
| James Paul Scopa Director - [D] | 103 334 | 10 333 | |
| Setareh Seyedkazemi CHIEF DEVELOPMENT OFFICER - [O] | 13 768 | 13 768 |
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|---|---|---|
| Peter Soparkar CHIEF OPERATING OFFICER - [O] | 39 154 | 39 154 | |
| Spivey Richard N. Director - [D] | 70 804 | 7 080 | |
| Dawn Svoronos Director - [D] | 50 000 | 5 000 | |
| Michael Swartzburg Principal Accounting Officer - [O] | 82 113 | 82 113 | |
| Jack Anthony Thrift Interim CFO - [O] | 0 | 0 | |
| Angela Thedinga Chief Technology Officer - [O] | 150 000 | 15 000 | |
| Reed Vaughn Tuckson Director - [D] | 0 | 0 | |
|
Venrock Healthcare Capital Partners Lp
10% Owner -
|
2 365 471 | 2 365 471 | |
|
VHCP Co-Investment Holdings II, LLC
10% Owner -
|
2 365 471 | 2 365 471 | |
|
VHCP Co-Investment Holdings, LLC
10% Owner -
|
2 365 471 | 2 365 471 | |
|
VHCP Management II, LLC
10% Owner -
|
2 365 471 | 2 365 471 | |
|
VHCP Management, LLC
10% Owner -
|
2 365 471 | 2 365 471 | |
|
Venrock Associates VI, L.P.
10% Owner -
|
2 365 471 | 2 365 471 | |
|
Venrock Healthcare Capital Partners II, L.P.
10% Owner -
|
2 365 471 | 2 365 471 | |
|
Venrock Management VI, LLC
10% Owner -
|
2 365 471 | 2 365 471 | |
|
Venrock Partners Management VI, LLC
10% Owner -
|
2 365 471 | 2 365 471 | |
|
Venrock Partners VI, L.P.
10% Owner -
|
2 365 471 | 2 365 471 | |
|
Versant Capital IV (Switzerland) GmbH
10% Owner -
|
7 344 627 | 734 463 | |
|
Versant IV Luxco S.a r.l.
10% Owner -
|
7 344 627 | 734 463 | |
|
Versant Venture Capital IV, L.P.
10% Owner -
|
7 344 627 | 734 463 | |
|
Versant Ventures IV, LLC
10% Owner -
|
7 344 627 | 734 463 | |
| Paul Wachter Director - [D] | 31 951 | 31 951 | |
| Scott M Whitcup Director - [D] | 0 | 0 | |
| Thomas Woiwode Director - [D] | 18 822 | 1 882 | |
|
Zygtech, LLC
10% Owner -
|
2 438 176 | 2 438 176 |
Report errors via our new Insider Auditing Tool
Track Records av insiderköp - Kortsiktig vinstanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i ADVM / Adverum Biotechnologies, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste köpen på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Track Records av insiderförsäljning - Kortsiktig förlustanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i ADVM / Adverum Biotechnologies, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste försäljningarna på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Transaktionshistorik
Klicka på länkikonen för att se hela transaktionshistoriken. Transaktioner som rapporteras som en del av en automatisk handelsplan 10b5-1 kommer att ha ett X i kolumnen markerad 10b-5.
| Fil datum |
Handel datum |
Schema | Insider | Ticker | Värdepappertitel | Kod | Direkta | Utövningspris | Enhet pris |
Enheter ändrad |
Värde ändrad (1K) |
Kvarvarande Optioner |
Kvarvarande Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-05-16 | 2025-05-15 | 4 | Fischer Laurent | ADVM | Common Stock | D | 2,0000 | −9 126 | −18 | 87 488 | ||||
| 2025-05-16 | 2025-05-15 | 4 | Soparkar Peter | ADVM | Common Stock | D | 2,0000 | −2 960 | −6 | 39 154 | ||||
| 2025-05-16 | 2025-05-15 | 4 | Seyedkazemi Setareh | ADVM | Common Stock | D | 2,0000 | −924 | −2 | 13 768 | ||||
| 2025-04-28 | 2025-03-27 | 4/A | Leonard Braden Michael | ADVM | Common Stock | D | 5,1883 | 16 593 | 86 | 141 800 | ||||
| 2025-04-28 | 2025-03-26 | 4/A | Leonard Braden Michael | ADVM | Common Stock | D | 5,0395 | 20 407 | 103 | 125 207 | ||||
| 2025-04-28 | 2025-03-27 | 4 | Leonard Braden Michael | ADVM | Common Stock | D | 5,1883 | 16 593 | 86 | 141 800 | ||||
| 2025-04-28 | 2025-03-26 | 4 | Leonard Braden Michael | ADVM | Common Stock | D | 5,0395 | 20 407 | 103 | 125 207 | ||||
| 2025-04-24 | 2025-04-23 | 4 | Leonard Braden Michael | ADVM | Common Stock | D | 2,9790 | 50 000 | 149 | 191 800 | ||||
| 2025-04-24 | 2025-04-22 | 4 | Leonard Braden Michael Holdings of BML Investment Partners, L.P. | ADVM | Common Stock | I | 3,0000 | 300 000 | 900 | 3 057 526 | ||||
| 2025-04-02 | 2025-04-02 | 4 | Leonard Braden Michael Holdings of BML Investment Partners, L.P | ADVM | Common Stock | I | 4,0376 | 15 209 | 61 | 2 757 526 | ||||
| 2025-04-02 | 2025-03-31 | 4 | Leonard Braden Michael Holdings of BML Investment Partners, L.P. | ADVM | Common Stock | I | 4,3784 | 19 566 | 86 | 2 742 317 | ||||
| 2025-03-27 | 2025-03-27 | 4 | Leonard Braden Michael | ADVM | Common Stock | D | 5,1883 | −16 593 | −86 | 141 800 | ||||
| 2025-03-27 | 2025-03-26 | 4 | Leonard Braden Michael | ADVM | Common Stock | D | 5,0395 | 20 407 | 103 | 125 207 | ||||
| 2025-03-20 | 2025-03-20 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stovk | I | 5,6133 | 30 600 | 172 | 2 722 761 | ||||
| 2025-03-20 | 2025-03-19 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stock | I | 4,9356 | 25 000 | 123 | 2 692 161 | ||||
| 2025-03-20 | 2025-03-18 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stock | I | 4,7274 | 44 341 | 210 | 2 667 161 | ||||
| 2025-03-20 | 2025-03-18 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stock | I | 4,6000 | 18 000 | 83 | 2 622 820 | ||||
| 2025-02-28 | 2025-02-28 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stock | I | 4,5965 | 85 068 | 391 | 2 604 820 | ||||
| 2025-02-28 | 2025-02-27 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stock | I | 4,4595 | 86 802 | 387 | 2 519 752 | ||||
| 2025-02-28 | 2025-02-26 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stock | I | 4,0087 | 164 886 | 661 | 2 432 950 | ||||
| 2025-02-27 | 2025-02-25 | 4 | Rubinstein Linda M | ADVM | Common Stock | D | 8 125 | 19 325 | ||||||
| 2025-02-27 | 2025-02-25 | 4 | Fischer Laurent | ADVM | Common Stock | D | 25 000 | 96 614 | ||||||
| 2025-02-27 | 2025-02-25 | 4 | Seyedkazemi Setareh | ADVM | Common Stock | D | 8 125 | 14 692 | ||||||
| 2025-02-27 | 2025-02-25 | 4 | Ozden Rabia Gurses | ADVM | Common Stock | D | 8 125 | 8 125 | ||||||
| 2025-02-27 | 2025-02-25 | 4 | Soparkar Peter | ADVM | Common Stock | D | 13 125 | 42 114 | ||||||
| 2024-07-31 | 2024-07-30 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stock | I | 7,1500 | 85 800 | 613 | 2 268 064 | ||||
| 2024-07-18 | 3 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stock | I | 2 103 176 | ||||||||
| 2024-07-18 | 3 | Leonard Braden Michael | ADVM | Common Stock | D | 104 800 | ||||||||
| 2024-07-18 | 2024-07-18 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stock | I | 9,1149 | 80 718 | 736 | 2 182 264 | ||||
| 2024-07-18 | 2024-07-17 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ADVM | Common Stock | I | 7,7459 | 135 546 | 1 050 | 2 101 546 | ||||
| 2024-02-09 | 2024-02-07 | 4 | Scopa James Paul | ADVM | Common Stock | D | 1,3500 | 100 000 | 135 | 100 000 | ||||
| 2024-02-09 | 2024-02-07 | 4 | Lupher, Jr. Mark L. | ADVM | Common Stock | D | 1,3500 | 130 000 | 176 | 130 000 | ||||
| 2023-11-06 | 3 | Nicholson, C. David | ADVM | No securities owned. | D | 0 | ||||||||
| 2023-09-18 | 2023-09-15 | 4 | Seyedkazemi Setareh | ADVM | Common Stock | D | 1,5486 | −130 | −0 | 47 674 | ||||
| 2023-09-18 | 2023-09-15 | 4 | Seyedkazemi Setareh | ADVM | Common Stock | D | 1,5200 | −6 071 | −9 | 47 804 | ||||
| 2023-06-09 | 2023-06-07 | 4 | Rubinstein Linda M | ADVM | Common Stock | D | 1,4549 | 100 000 | 145 | 100 000 | ||||
| 2023-03-17 | 2023-03-15 | 4 | Soparkar Peter | ADVM | Common Stock | D | 0,7816 | −13 360 | −10 | 265 891 | ||||
| 2023-03-17 | 2023-03-15 | 4 | Riley Brigit | ADVM | Common Stock | D | 0,7816 | −7 299 | −6 | 117 435 | ||||
| 2023-03-17 | 2023-03-15 | 4 | Fischer Laurent | ADVM | Common Stock | D | 0,7816 | −41 239 | −32 | 692 141 | ||||
| 2022-12-15 | 3 | Rubinstein Linda M | ADVM | No securities are beneficially owned. | D | 0 | ||||||||
| 2022-09-21 | 2022-09-19 | 4 | Seyedkazemi Setareh | ADVM | Common Stock | D | 1,0696 | −6 058 | −6 | 47 875 | ||||
| 2022-09-21 | 2022-09-19 | 4 | Beckman Richard | ADVM | Common Stock | D | 1,0697 | −4 272 | −5 | 39 061 | ||||
| 2022-09-21 | 2022-09-19 | 4 | Soparkar Peter | ADVM | Common Stock | D | 1,0697 | −13 305 | −14 | 273 251 | ||||
| 2022-09-21 | 2022-09-19 | 4 | Riley Brigit | ADVM | Common Stock | D | 1,0697 | −7 266 | −8 | 118 734 | ||||
| 2022-09-21 | 2022-09-19 | 4 | Fischer Laurent | ADVM | Common Stock | D | 1,0696 | −41 082 | −44 | 727 380 | ||||
| 2022-09-21 | 2022-09-14 | 4/A | Beckman Richard | ADVM | Common Stock | D | 33 333 | 43 333 | ||||||
| 2022-09-16 | 2022-09-14 | 4 | Beckman Richard | ADVM | Common Stock | D | 25 000 | 35 000 | ||||||
| 2022-09-16 | 2022-09-14 | 4 | Seyedkazemi Setareh | ADVM | Common Stock | D | 33 333 | 53 933 | ||||||
| 2022-06-10 | 3 | Rakow John | ADVM | Common Stock | D | 58 233 | ||||||||
| 2022-06-07 | 3 | PECOTA NANCY E | ADVM | No securities owned | D | 0 | ||||||||
| 2022-05-24 | 2022-05-23 | 4 | Seyedkazemi Setareh | ADVM | Common Stock | D | 0,8400 | 20 000 | 17 | 20 600 | ||||
| 2022-05-19 | 2022-05-17 | 4 | Beckman Richard | ADVM | Common Stock | D | 0,8228 | 10 000 | 8 | 10 000 | ||||
| 2022-05-18 | 2022-05-16 | 4 | Svoronos Dawn | ADVM | Common Stock | D | 0,8526 | 30 000 | 26 | 50 000 | ||||
| 2022-05-17 | 2022-05-17 | 4 | D'Souza Rupert | ADVM | Common Stock | D | 0,8272 | 10 000 | 8 | 20 850 | ||||
| 2022-05-17 | 2022-05-13 | 4 | D'Souza Rupert | ADVM | Common Stock | D | 0,8585 | 10 000 | 9 | 10 850 | ||||
| 2022-04-22 | 2022-04-20 | 4 | Fischer Laurent | ADVM | Common Stock | D | 1,1120 | 25 000 | 28 | 762 462 | ||||
| 2022-04-20 | 2022-04-19 | 4 | Soparkar Peter | ADVM | Common Stock | D | 1,1400 | 21 750 | 25 | 280 556 | ||||
| 2022-04-20 | 2022-04-19 | 4 | Soparkar Peter | ADVM | Common Stock | D | 1,1373 | 175 | 0 | 258 806 | ||||
| 2022-03-18 | 2022-03-17 | 4 | Hong Soo | ADVM | Stock Option (Right to Buy) | D | 1,35 | 80 000 | 80 000 | |||||
| 2022-03-18 | 3 | Hong Soo | ADVM | No securities owned. | D | 0 | ||||||||
| 2022-03-18 | 2022-03-17 | 4 | Ozden Rabia Gurses | ADVM | Stock Option (Right to Buy) | D | 1,35 | 80 000 | 80 000 | |||||
| 2022-03-18 | 3 | Ozden Rabia Gurses | ADVM | No securities owned. | D | 0 | ||||||||
| 2022-03-17 | 2022-03-08 | 4 | Riley Brigit | ADVM | Stock Option (Right to Buy) | D | 1,29 | 195 000 | 195 000 | |||||
| 2022-03-17 | 2022-03-08 | 4 | Soparkar Peter | ADVM | Stock Option (Right to Buy) | D | 1,29 | 255 000 | 255 000 | |||||
| 2022-03-17 | 2022-03-08 | 4 | Fischer Laurent | ADVM | Stock Option (Right to Buy) | D | 1,29 | 630 000 | 630 000 | |||||
| 2022-02-09 | 2022-02-07 | 4 | Beckman Richard | ADVM | Stock Option (Right to Buy) | D | 1,58 | 485 000 | 485 000 | |||||
| 2022-02-09 | 3 | Beckman Richard | ADVM | No securities owned. | D | 0 | ||||||||
| 2022-01-10 | 2022-01-06 | 4 | Seyedkazemi Setareh | ADVM | Stock Option (Right to Buy) | D | 1,73 | 425 000 | 425 000 | |||||
| 2022-01-10 | 3 | Seyedkazemi Setareh | ADVM | Common Stock | D | 600 | ||||||||
| 2021-12-10 | 2021-12-09 | 4 | Fischer Laurent | ADVM | Common Stock | D | 1,8500 | 14 323 | 26 | 737 462 | ||||
| 2021-12-10 | 2021-12-08 | 4 | Fischer Laurent | ADVM | Common Stock | D | 1,7900 | 10 677 | 19 | 723 139 | ||||
| 2021-12-10 | 2021-12-08 | 4 | Soparkar Peter | ADVM | Common Stock | D | 1,9100 | 25 000 | 48 | 258 631 | ||||
| 2021-12-08 | 2021-12-06 | 4 | D'Souza Rupert | ADVM | Stock Option (Right to Buy) | D | 1,77 | 400 000 | 400 000 | |||||
| 2021-12-08 | 3 | D'Souza Rupert | ADVM | Common Stock | D | 850 | ||||||||
| 2021-11-17 | 2021-11-15 | 4 | Scopa James Paul By Trust | ADVM | Common Stock | I | 2,1800 | −50 000 | −109 | 3 334 | ||||
| 2021-10-04 | 2021-09-30 | 4 | Clark Julie | ADVM | Common Stock | D | 2,1700 | −4 766 | −10 | 164 723 | ||||
| 2021-09-14 | 3 | Riley Brigit | ADVM | Common Stock | D | 120 000 | ||||||||
| 2021-09-13 | 3 | THRIFT JACK ANTHONY | ADVM | No securities owned. | D | 0 | ||||||||
| 2021-08-10 | 2021-08-06 | 4 | Clark Julie | ADVM | Common Stock | D | 120 000 | 169 489 | ||||||
| 2021-08-10 | 2021-08-06 | 4 | Soparkar Peter | ADVM | Stock Option (Right to Buy) | D | 2,48 | 160 000 | 160 000 | |||||
| 2021-08-10 | 2021-08-06 | 4 | Soparkar Peter | ADVM | Common Stock | D | 220 000 | 230 692 | ||||||
| 2021-08-10 | 2021-08-06 | 4 | Thedinga Angela | ADVM | Stock Option (Right to Buy) | D | 2,48 | 120 000 | 120 000 | |||||
| 2021-08-10 | 2021-08-06 | 4 | Thedinga Angela | ADVM | Common Stock | D | 150 000 | 150 000 | ||||||
| 2021-08-10 | 2021-08-06 | 4 | Fischer Laurent | ADVM | Stock Option (Right to Buy) | D | 2,48 | 455 000 | 455 000 | |||||
| 2021-08-10 | 2021-08-06 | 4 | Fischer Laurent | ADVM | Common Stock | D | 680 000 | 706 292 | ||||||
| 2021-06-03 | 2021-06-01 | 4 | Clark Julie | ADVM | Stock Option (Right to Buy) | D | 3,51 | 400 000 | 400 000 | |||||
| 2021-06-03 | 3 | Clark Julie | ADVM | Common Stock | D | 49 489 | ||||||||
| 2021-05-14 | 2021-05-12 | 4 | Woiwode Thomas | ADVM | Stock Option (Right to Buy) | D | 3,70 | 40 000 | 40 000 | |||||
| 2021-05-14 | 2021-05-12 | 4 | Svoronos Dawn | ADVM | Stock Option (Right to Buy) | D | 3,70 | 40 000 | 40 000 | |||||
| 2021-05-14 | 2021-05-12 | 4 | Whitcup Scott M | ADVM | Stock Option (Right to Buy) | D | 3,70 | 40 000 | 40 000 | |||||
| 2021-05-14 | 2021-05-12 | 4 | Scopa James Paul | ADVM | Stock Option (Right to Buy) | D | 3,70 | 40 000 | 40 000 | |||||
| 2021-05-14 | 2021-05-12 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 3,70 | 40 000 | 40 000 | |||||
| 2021-05-14 | 2021-05-12 | 4 | Lupher, Jr. Mark L. | ADVM | Stock Option (Right to Buy) | D | 3,70 | 40 000 | 40 000 | |||||
| 2021-05-14 | 2021-05-12 | 4 | Machado Patrick | ADVM | Stock Option (Right to Buy) | D | 3,70 | 12 500 | 12 500 | |||||
| 2021-05-14 | 2021-05-12 | 4 | Machado Patrick | ADVM | Stock Option (Right to Buy) | D | 3,70 | 40 000 | 40 000 | |||||
| 2021-04-01 | 2021-03-31 | 4 | Svoronos Dawn | ADVM | Common Stock | D | 10,0169 | 20 000 | 200 | 20 000 | ||||
| 2021-03-24 | 2021-03-24 | 4 | Fischer Laurent | ADVM | Common Stock | D | 9,8780 | 10 000 | 99 | 26 292 | ||||
| 2021-03-24 | 2021-03-24 | 4 | Machado Patrick | ADVM | Common Stock | D | 9,9196 | 10 000 | 99 | 88 182 | ||||
| 2021-02-23 | 2021-02-19 | 4 | Tuckson Reed Vaughn | ADVM | Stock Option (Right to Buy) | D | 12,85 | 45 000 | 45 000 | |||||
| 2021-02-23 | 3 | Tuckson Reed Vaughn | ADVM | No securities owned. | D | 0 | ||||||||
| 2021-02-18 | 2021-02-16 | 4 | Thedinga Angela | ADVM | Stock Option (Right to Buy) | D | 13,44 | 250 000 | 250 000 | |||||
| 2021-02-18 | 2021-02-16 | 4 | Soparkar Peter | ADVM | Stock Option (Right to Buy) | D | 13,44 | 140 000 | 140 000 | |||||
| 2021-02-18 | 2021-02-16 | 4 | Osborne Aaron | ADVM | Stock Option (Right to Buy) | D | 13,44 | 150 000 | 150 000 | |||||
| 2021-02-18 | 2021-02-16 | 4 | PATTERSON LEONE D | ADVM | Stock Option (Right to Buy) | D | 13,44 | 240 000 | 240 000 | |||||
| 2021-02-18 | 2021-02-16 | 4 | Fischer Laurent | ADVM | Stock Option (Right to Buy) | D | 13,44 | 680 000 | 680 000 | |||||
| 2021-02-11 | 2021-02-09 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 14,1393 | −62 | −1 | 97 955 | ||||
| 2021-02-11 | 2021-02-09 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 14,1000 | −12 471 | −176 | 98 017 | ||||
| 2021-01-19 | 2021-01-15 | 4 | Machado Patrick | ADVM | Common Stock | D | 11,5174 | 10 000 | 115 | 78 182 | ||||
| 2021-01-19 | 2021-01-15 | 4 | Fischer Laurent | ADVM | Common Stock | D | 11,5338 | 8 600 | 99 | 16 292 | ||||
| 2020-12-16 | 2020-12-14 | 4 | Woiwode Thomas | ADVM | Common Stock | D | 12 783 | 18 822 | ||||||
| 2020-12-11 | 3 | Svoronos Dawn | ADVM | No Securities Owned | D | 0 | ||||||||
| 2020-12-11 | 2020-12-09 | 4 | Svoronos Dawn | ADVM | Stock Option (Right to Buy) | D | 12,82 | 45 000 | 45 000 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Fischer Laurent | ADVM | Common Stock | D | 13,0000 | 7 692 | 100 | 7 692 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Soparkar Peter | ADVM | Common Stock | D | 13,0000 | 7 692 | 100 | 10 692 | ||||
| 2020-07-22 | 2020-07-20 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −5 000 | 78 000 | |||||
| 2020-07-22 | 2020-07-20 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 17,5956 | −5 000 | −88 | 274 442 | ||||
| 2020-07-22 | 2020-07-20 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 5 000 | 24 | 279 442 | ||||
| 2020-06-25 | 2020-06-23 | 4 | Carter Eric G | ADVM | Stock Option (Right to Buy) | D | 25,64 | 30 000 | 30 000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Hemrajani Rekha | ADVM | Stock Option (Right to Buy) | D | 25,64 | 30 000 | 30 000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Woiwode Thomas | ADVM | Stock Option (Right to Buy) | D | 25,64 | 30 000 | 30 000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Machado Patrick | ADVM | Stock Option (Right to Buy) | D | 25,64 | 30 000 | 30 000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Scopa James Paul | ADVM | Stock Option (Right to Buy) | D | 25,64 | 30 000 | 30 000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 25,64 | 30 000 | 30 000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Lupher, Jr. Mark L. | ADVM | Stock Option (Right to Buy) | D | 25,64 | 30 000 | 30 000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Whitcup Scott M | ADVM | Stock Option (Right to Buy) | D | 25,64 | 30 000 | 30 000 | |||||
| 2020-06-23 | 2020-06-22 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −23 605 | 83 000 | |||||
| 2020-06-23 | 2020-06-22 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 25,0632 | −23 605 | −592 | 274 442 | ||||
| 2020-06-23 | 2020-06-22 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 23 605 | 113 | 298 047 | ||||
| 2020-06-18 | 2020-06-18 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −11 127 | 106 605 | |||||
| 2020-06-18 | 2020-06-18 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 25,0138 | −11 127 | −278 | 274 442 | ||||
| 2020-06-18 | 2020-06-18 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 11 127 | 53 | 285 569 | ||||
| 2020-06-18 | 2020-06-17 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −268 | 117 732 | |||||
| 2020-06-18 | 2020-06-17 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 25,0101 | −268 | −7 | 274 442 | ||||
| 2020-06-18 | 2020-06-17 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 268 | 1 | 274 710 | ||||
| 2020-06-17 | 2020-06-16 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 24,6800 | −13 171 | −325 | 110 488 | ||||
| 2020-06-17 | 3 | Fischer Laurent | ADVM | No securities owned. | D | 0 | ||||||||
| 2020-06-17 | 2020-06-15 | 4 | Fischer Laurent | ADVM | Stock Option (Right to Buy) | D | 23,70 | 1 200 000 | 1 200 000 | |||||
| 2020-06-17 | 2020-06-15 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −10 000 | 118 000 | |||||
| 2020-06-17 | 2020-06-15 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 23,5923 | −159 | −4 | 274 442 | ||||
| 2020-06-17 | 2020-06-15 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 23,0034 | −3 425 | −79 | 274 601 | ||||
| 2020-06-17 | 2020-06-15 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 21,9259 | −1 416 | −31 | 278 026 | ||||
| 2020-06-17 | 2020-06-15 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 21,0084 | −5 000 | −105 | 279 442 | ||||
| 2020-06-17 | 2020-06-15 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 10 000 | 48 | 284 442 | ||||
| 2020-05-22 | 2020-05-21 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −3 599 | 128 000 | |||||
| 2020-05-22 | 2020-05-21 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 20,0189 | 3 599 | 72 | 274 442 | ||||
| 2020-05-22 | 2020-05-21 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 3 599 | 17 | 278 041 | ||||
| 2020-05-22 | 2020-05-20 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −1 401 | 131 599 | |||||
| 2020-05-22 | 2020-05-20 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 20,0071 | −1 401 | −28 | 274 442 | ||||
| 2020-05-22 | 2020-05-20 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 1 401 | 7 | 275 843 | ||||
| 2020-05-20 | 2020-02-12 | 4/A | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −10 000 | 178 000 | |||||
| 2020-05-20 | 2020-02-12 | 4/A | Gasmi Mehdi | ADVM | Common Stock | D | 15,0690 | −10 000 | −151 | 274 442 | ||||
| 2020-05-20 | 2020-02-12 | 4/A | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 10 000 | 48 | 284 442 | ||||
| 2020-05-20 | 2020-02-12 | 4/A | Gasmi Mehdi | ADVM | Common Stock | D | 15,0500 | −15 494 | −233 | 274 442 | ||||
| 2020-05-20 | 2020-02-12 | 4/A | Gasmi Mehdi | ADVM | Common Stock | D | 11,3300 | −31 482 | −357 | 289 936 | ||||
| 2020-05-20 | 2020-01-15 | 4/A | Gasmi Mehdi | ADVM | Common Stock | D | 88 496 | 321 418 | ||||||
| 2020-05-20 | 2020-05-18 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −5 000 | 133 000 | |||||
| 2020-05-20 | 2020-05-18 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 19,0300 | −300 | −6 | 274 442 | ||||
| 2020-05-20 | 2020-05-18 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 18,1115 | −4 700 | −85 | 274 742 | ||||
| 2020-05-20 | 2020-05-18 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 5 000 | 24 | 279 442 | ||||
| 2020-05-20 | 2020-05-06 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −25 000 | 138 000 | |||||
| 2020-05-20 | 2020-05-06 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 20,0267 | −25 000 | −501 | 274 442 | ||||
| 2020-05-20 | 2020-05-06 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 25 000 | 120 | 299 442 | ||||
| 2020-05-20 | 2020-05-05 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −10 000 | 163 000 | |||||
| 2020-05-20 | 2020-05-05 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 16,2573 | −10 000 | −163 | 274 442 | ||||
| 2020-05-20 | 2020-05-05 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 10 000 | 48 | 284 442 | ||||
| 2020-05-08 | 2020-02-09 | 4/A | PATTERSON LEONE D | ADVM | Common Stock | D | 10,2400 | −10 985 | −112 | 139 235 | ||||
| 2020-05-08 | 2020-05-06 | 4 | PATTERSON LEONE D | ADVM | Stock Option (Right to Buy) | D | 3,44 | −20 000 | 155 576 | |||||
| 2020-05-08 | 2020-05-06 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 20,0200 | −20 000 | −400 | 123 659 | ||||
| 2020-05-08 | 2020-05-06 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 3,4400 | 20 000 | 69 | 143 659 | ||||
| 2020-05-05 | 2020-05-04 | 4 | Scopa James Paul | ADVM | Stock Option (Right to Buy) | D | 6,48 | −23 334 | 46 666 | |||||
| 2020-05-05 | 2020-05-04 | 4 | Scopa James Paul By Trust | ADVM | Common Stock | I | 6,4800 | 23 334 | 151 | 53 334 | ||||
| 2020-04-20 | 3 | Whitcup Scott M | ADVM | No securities owned. | D | 0 | ||||||||
| 2020-04-20 | 2020-04-16 | 4 | Whitcup Scott M | ADVM | Stock Option (Right to Buy) | D | 11,62 | 60 000 | 60 000 | |||||
| 2020-03-25 | 2020-03-20 | 4 | PATTERSON LEONE D | ADVM | Stock Option (Right to Buy) | D | 3,44 | −24 424 | 175 576 | |||||
| 2020-03-25 | 2020-03-20 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 10,1682 | −39 526 | −402 | 123 429 | ||||
| 2020-03-25 | 2020-03-20 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 3,4400 | 24 424 | 84 | 162 955 | ||||
| 2020-03-18 | 2020-03-17 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 10,0195 | −474 | −5 | 138 531 | ||||
| 2020-02-25 | 2020-02-21 | 4 | Thedinga Angela | ADVM | Stock Option (Right to Buy) | D | 14,84 | 150 000 | 150 000 | |||||
| 2020-02-25 | 3 | Thedinga Angela | ADVM | Common Stock | D | 0 | ||||||||
| 2020-02-21 | 2020-02-20 | 4 | Osborne Aaron | ADVM | Stock Option (Right to Buy) | D | 15,75 | 150 000 | 150 000 | |||||
| 2020-02-21 | 2020-02-20 | 4 | Leung Thomas | ADVM | Stock Option (Right to Buy) | D | 15,75 | 120 000 | 120 000 | |||||
| 2020-02-21 | 2020-02-20 | 4 | Soparkar Peter | ADVM | Stock Option (Right to Buy) | D | 15,75 | 40 750 | 40 750 | |||||
| 2020-02-21 | 2020-02-20 | 4 | PATTERSON LEONE D | ADVM | Stock Option (Right to Buy) | D | 15,75 | 300 000 | 300 000 | |||||
| 2020-02-20 | 2020-02-18 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | 5 000 | 173 000 | |||||
| 2020-02-20 | 2020-02-18 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 16,2312 | −5 000 | −81 | 258 979 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 5 000 | 24 | 263 979 | ||||
| 2020-02-14 | 2020-02-09 | 4/A | Gasmi Mehdi | ADVM | Common Stock | D | 10,2400 | −15 494 | −159 | 274 473 | ||||
| 2020-02-14 | 2020-02-12 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 4,80 | −10 000 | 178 000 | |||||
| 2020-02-14 | 2020-02-12 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 15,0690 | −10 000 | −151 | 258 979 | ||||
| 2020-02-14 | 2020-02-12 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 4,8000 | 10 000 | 48 | 268 979 | ||||
| 2020-02-14 | 2020-02-12 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 15,0500 | −15 494 | −233 | 258 979 | ||||
| 2020-02-14 | 2020-02-12 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 11,3300 | −31 451 | −356 | 289 967 | ||||
| 2020-02-14 | 2020-01-15 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 88 496 | 321 418 | ||||||
| 2020-02-14 | 2020-02-14 | 4 | Scopa James Paul By Trust | ADVM | Common Stock | I | 13,7500 | 10 000 | 138 | 30 000 | ||||
| 2020-02-10 | 2019-12-23 | 4/A | PATTERSON LEONE D | ADVM | Common Stock | D | 10,7200 | −40 000 | −429 | 150 220 | ||||
| 2020-02-10 | 2018-06-15 | 4/A | Gasmi Mehdi | ADVM | Common Stock | D | 88 496 | 345 258 | ||||||
| 2020-02-10 | 2020-02-09 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 10,2400 | −11 551 | −118 | 309 867 | ||||
| 2020-02-10 | 2019-06-15 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 10,8200 | −35 282 | −382 | 190 220 | ||||
| 2020-02-10 | 2019-06-15 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 10,8200 | −8 570 | −93 | 225 502 | ||||
| 2020-02-10 | 2019-02-09 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 3,3300 | −8 176 | −27 | 234 072 | ||||
| 2020-02-10 | 2018-06-15 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 5,5500 | −8 645 | −48 | 242 248 | ||||
| 2020-02-10 | 2018-02-09 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 7,0500 | −8 208 | −58 | 162 397 | ||||
| 2020-02-10 | 2017-06-15 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 2,7000 | −9 395 | −25 | 170 605 | ||||
| 2020-02-10 | 2019-04-21 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 5,9800 | −589 | −4 | 321 418 | ||||
| 2020-02-10 | 2019-02-12 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 3,5500 | −10 652 | −38 | 322 007 | ||||
| 2020-02-10 | 2019-02-09 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 3,3300 | −12 599 | −42 | 332 659 | ||||
| 2020-02-10 | 2018-04-21 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 6,3000 | −605 | −4 | 247 762 | ||||
| 2020-02-10 | 2018-02-12 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 6,8500 | −10 806 | −74 | 248 367 | ||||
| 2020-02-10 | 2018-02-09 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 7,0500 | −11 433 | −81 | 259 173 | ||||
| 2020-02-10 | 2017-08-21 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 2,5000 | −5 479 | −14 | 270 606 | ||||
| 2020-02-10 | 2017-04-21 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 2,7000 | −657 | −2 | 276 085 | ||||
| 2020-02-10 | 2017-02-12 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 3,0000 | −12 793 | −38 | 276 742 | ||||
| 2020-02-10 | 2020-02-09 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 10,2400 | −11 215 | −115 | 139 005 | ||||
| 2020-01-03 | 2020-01-01 | 4 | Machado Patrick | ADVM | Stock Option (Right to Buy) | D | 11,52 | 15 000 | 15 000 | |||||
| 2019-12-26 | 2019-12-23 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 10,7200 | −40 000 | −429 | 228 496 | ||||
| 2019-11-01 | 3 | Soparkar Peter | ADVM | No securities owned. | D | 0 | ||||||||
| 2019-11-01 | 2019-10-30 | 4 | Soparkar Peter | ADVM | Stock Option (Right to Buy) | D | 6,88 | 400 000 | 400 000 | |||||
| 2019-10-25 | 2019-07-31 | 4/A | Finer Mitchell H. | ADVM | Stock Option (Right to Buy) | D | 13,41 | 0 | 0 | |||||
| 2019-08-16 | 2019-08-15 | 4 | Hemrajani Rekha | ADVM | Stock Option (Right to Buy) | D | 13,41 | 33 750 | 45 000 | |||||
| 2019-08-16 | 2019-08-15 | 4 | Scopa James Paul | ADVM | Stock Option (Right to Buy) | D | 13,41 | 33 750 | 45 000 | |||||
| 2019-08-16 | 2019-08-15 | 4 | Lupher, Jr. Mark L. | ADVM | Stock Option (Right to Buy) | D | 13,41 | 33 750 | 45 000 | |||||
| 2019-08-02 | 2019-07-31 | 4 | Hemrajani Rekha | ADVM | Stock Option (Right to Buy) | D | 13,41 | 11 250 | 11 250 | |||||
| 2019-08-02 | 2019-07-31 | 4 | Lupher, Jr. Mark L. | ADVM | Stock Option (Right to Buy) | D | 13,41 | 11 250 | 11 250 | |||||
| 2019-08-02 | 2019-07-31 | 4 | Scopa James Paul | ADVM | Stock Option (Right to Buy) | D | 13,41 | 11 250 | 11 250 | |||||
| 2019-08-02 | 2019-07-31 | 4 | Finer Mitchell H. | ADVM | Stock Option (Right to Buy) | D | 13,41 | 45 000 | 45 000 | |||||
| 2019-08-02 | 2019-07-31 | 4 | Woiwode Thomas | ADVM | Stock Option (Right to Buy) | D | 13,41 | 45 000 | 45 000 | |||||
| 2019-08-02 | 2019-07-31 | 4 | Carter Eric G | ADVM | Stock Option (Right to Buy) | D | 13,41 | 45 000 | 45 000 | |||||
| 2019-08-02 | 2019-07-31 | 4 | Spivey Richard N. | ADVM | Stock Option (Right to Buy) | D | 13,41 | 45 000 | 45 000 | |||||
| 2019-08-02 | 2019-07-31 | 4 | Machado Patrick | ADVM | Stock Option (Right to Buy) | D | 13,41 | 45 000 | 45 000 | |||||
| 2019-05-06 | 2019-05-06 | 4 | Scopa James Paul By Trust | ADVM | Common Stock | I | 6,7100 | 20 000 | 134 | 20 000 | ||||
| 2019-05-03 | 2019-05-01 | 4 | Hemrajani Rekha | ADVM | Stock Option (Right to Buy) | D | 6,48 | 70 000 | 70 000 | |||||
| 2019-05-03 | 2019-05-01 | 4 | Lupher, Jr. Mark L. | ADVM | Stock Option (Right to Buy) | D | 6,48 | 70 000 | 70 000 | |||||
| 2019-05-03 | 2019-05-01 | 4 | Scopa James Paul | ADVM | Stock Option (Right to Buy) | D | 6,48 | 70 000 | 70 000 | |||||
| 2019-05-03 | 3 | Hemrajani Rekha | ADVM | No securities owned. | D | 0 | ||||||||
| 2019-05-03 | 3 | Lupher, Jr. Mark L. | ADVM | No securities owned. | D | 0 | ||||||||
| 2019-05-03 | 3 | Scopa James Paul | ADVM | No securities owned. | D | 0 | ||||||||
| 2019-04-25 | 3 | Leung Thomas | ADVM | No securities owned. | D | 0 | ||||||||
| 2019-04-25 | 2019-04-24 | 4 | Leung Thomas | ADVM | Stock Option (Right to Buy) | D | 6,62 | 450 000 | 450 000 | |||||
| 2019-04-02 | 3 | Osborne Aaron | ADVM | No securities owned. | D | 0 | ||||||||
| 2019-04-02 | 2019-04-01 | 4 | Osborne Aaron | ADVM | Stock Option (Right to Buy) | D | 5,41 | 450 000 | 450 000 | |||||
| 2019-02-19 | 2019-02-14 | 4 | PATTERSON LEONE D | ADVM | Stock Option (Right to Buy) | D | 3,50 | 800 000 | 800 000 | |||||
| 2019-02-19 | 2019-02-14 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 3,50 | 225 000 | 225 000 | |||||
| 2019-02-19 | 2019-02-14 | 4 | Cheng Jennifer C. | ADVM | Stock Option (Right to Buy) | D | 3,50 | 80 000 | 80 000 | |||||
| 2018-10-22 | 2018-10-18 | 4 | PATTERSON LEONE D | ADVM | Stock Option (Right to Buy) | D | 4,70 | 150 000 | 150 000 | |||||
| 2018-06-18 | 2018-06-15 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 88 496 | 268 496 | ||||||
| 2018-06-18 | 2018-06-15 | 4 | Cheng Jennifer C. | ADVM | Common Stock | D | 11 150 | 118 863 | ||||||
| 2018-06-18 | 2018-06-15 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 88 496 | 387 031 | ||||||
| 2018-06-15 | 2018-05-31 | 4 | Finer Mitchell H. | ADVM | Stock Option (Right to Buy) | D | 6,25 | 35 000 | 35 000 | |||||
| 2018-06-15 | 2018-05-31 | 4 | Woiwode Thomas | ADVM | Stock Option (Right to Buy) | D | 6,25 | 35 000 | 35 000 | |||||
| 2018-06-15 | 2018-05-31 | 4 | Carter Eric G | ADVM | Stock Option (Right to Buy) | D | 6,25 | 35 000 | 35 000 | |||||
| 2018-06-15 | 2018-05-31 | 4 | Spivey Richard N. | ADVM | Stock Option (Right to Buy) | D | 6,25 | 35 000 | 35 000 | |||||
| 2018-06-15 | 2018-05-31 | 4 | Machado Patrick | ADVM | Stock Option (Right to Buy) | D | 6,25 | 35 000 | 35 000 | |||||
| 2018-06-15 | 2018-05-31 | 4 | Cleveland Paul B | ADVM | Stock Option (Right to Buy) | D | 6,25 | 35 000 | 35 000 | |||||
| 2018-02-20 | 2018-02-15 | 4 | Salzman Amber | ADVM | Stock Option (Right to Buy) | D | 6,40 | 478 000 | 478 000 | |||||
| 2018-02-20 | 2018-02-15 | 4 | Countouriotis Athena | ADVM | Stock Option (Right to Buy) | D | 6,40 | 160 000 | 160 000 | |||||
| 2018-02-20 | 2018-02-15 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 6,40 | 160 000 | 160 000 | |||||
| 2018-02-20 | 2018-02-15 | 4 | PATTERSON LEONE D | ADVM | Stock Option (Right to Buy) | D | 6,40 | 160 000 | 160 000 | |||||
| 2018-02-20 | 2018-02-15 | 4 | Cheng Jennifer C. | ADVM | Stock Option (Right to Buy) | D | 6,40 | 114 000 | 114 000 | |||||
| 2018-02-20 | 2018-02-15 | 4 | Machado Patrick | ADVM | Stock Option (Right to Buy) | D | 6,40 | 10 000 | 10 000 | |||||
| 2017-09-08 | 2017-09-07 | 4 | Carter Eric G | ADVM | Stock Option (Right to Buy) | D | 2,70 | 69 000 | 69 000 | |||||
| 2017-09-08 | 2017-09-07 | 4 | Carter Eric G | ADVM | Common Stock | D | 48 000 | 48 000 | ||||||
| 2017-06-21 | 2017-06-19 | 4 | Countouriotis Athena | ADVM | Stock Option (Right to Buy) | D | 2,90 | 213 000 | 213 000 | |||||
| 2017-06-21 | 2017-06-19 | 4 | Countouriotis Athena | ADVM | Common Stock | D | 150 000 | 150 000 | ||||||
| 2017-06-14 | 2017-06-12 | 4 | Woiwode Thomas | ADVM | Stock Option (Right to Buy) | D | 2,75 | 33 602 | 33 602 | |||||
| 2017-06-14 | 2017-06-12 | 4 | Woiwode Thomas | ADVM | Common Stock | D | 22 727 | 70 380 | ||||||
| 2017-06-14 | 2017-06-12 | 4 | Spivey Richard N. | ADVM | Stock Option (Right to Buy) | D | 2,75 | 33 602 | 33 602 | |||||
| 2017-06-14 | 2017-06-12 | 4 | Spivey Richard N. | ADVM | Common Stock | D | 22 727 | 70 804 | ||||||
| 2017-06-14 | 2017-06-12 | 4 | Finer Mitchell H. | ADVM | Stock Option (Right to Buy) | D | 2,75 | 33 602 | 33 602 | |||||
| 2017-06-14 | 2017-06-12 | 4 | Finer Mitchell H. | ADVM | Common Stock | D | 22 727 | 603 069 | ||||||
| 2017-06-14 | 2017-06-12 | 4 | Schwartz Steven Daniel | ADVM | Stock Option (Right to Buy) | D | 2,75 | 33 602 | 33 602 | |||||
| 2017-06-14 | 2017-06-12 | 4 | Schwartz Steven Daniel | ADVM | Common Stock | D | 22 727 | 398 991 | ||||||
| 2017-06-14 | 2017-06-12 | 4 | Cleveland Paul B | ADVM | Stock Option (Right to Buy) | D | 2,75 | 33 602 | 33 602 | |||||
| 2017-06-14 | 2017-06-12 | 4 | Cleveland Paul B | ADVM | Common Stock | D | 22 727 | 22 727 | ||||||
| 2017-06-14 | 2017-06-12 | 4 | Machado Patrick | ADVM | Stock Option (Right to Buy) | D | 2,75 | 33 602 | 33 602 | |||||
| 2017-06-14 | 2017-06-12 | 4 | Machado Patrick | ADVM | Common Stock | D | 22 727 | 68 182 | ||||||
| 2017-05-01 | 2017-04-28 | 4 | Woiwode Thomas | ADVM | Common Stock | D | 2 223 | 47 653 | ||||||
| 2017-04-21 | 2017-04-19 | 4 | Spivey Richard N. | ADVM | Stock Option (Right to Buy) | D | 2,60 | 69 061 | 69 061 | |||||
| 2017-04-21 | 2017-04-19 | 4 | Spivey Richard N. | ADVM | Common Stock | D | 48 077 | 48 077 | ||||||
| 2017-04-03 | 2017-03-31 | 4 | Woiwode Thomas | ADVM | Common Stock | D | 3 704 | 45 430 | ||||||
| 2017-03-16 | 2017-03-14 | 4 | Machado Patrick | ADVM | Stock Option (Right to Buy) | D | 2,75 | 64 767 | 64 767 | |||||
| 2017-03-16 | 2017-03-14 | 4 | Machado Patrick | ADVM | Common Stock | D | 45 455 | 45 455 | ||||||
| 2017-03-09 | 3 | Cheng Jennifer C. | ADVM | Common Stock | D | 215 426 | ||||||||
| 2017-03-09 | 3 | Cheng Jennifer C. | ADVM | Common Stock | D | 215 426 | ||||||||
| 2017-03-02 | 2017-02-28 | 4 | Woiwode Thomas | ADVM | Common Stock | D | 3 774 | 41 726 | ||||||
| 2017-02-13 | 2017-02-09 | 4 | Salzman Amber | ADVM | Stock Option (Right to Buy) | D | 2,70 | 378 000 | 378 000 | |||||
| 2017-02-13 | 2017-02-09 | 4 | Salzman Amber | ADVM | Common Stock | D | 262 000 | 891 766 | ||||||
| 2017-02-13 | 2017-02-09 | 4 | PATTERSON LEONE D | ADVM | Stock Option (Right to Buy) | D | 2,70 | 116 000 | 116 000 | |||||
| 2017-02-13 | 2017-02-09 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 80 000 | 180 000 | ||||||
| 2017-02-13 | 2017-02-09 | 4 | Barone Samuel B. | ADVM | Stock Option (Right to Buy) | D | 2,70 | 84 000 | 84 000 | |||||
| 2017-02-13 | 2017-02-09 | 4 | Barone Samuel B. | ADVM | Common Stock | D | 58 000 | 172 335 | ||||||
| 2017-02-13 | 2017-02-09 | 4 | Gasmi Mehdi | ADVM | Stock Option (Right to Buy) | D | 2,70 | 181 000 | 181 000 | |||||
| 2017-02-13 | 2017-02-09 | 4 | Gasmi Mehdi | ADVM | Common Stock | D | 125 000 | 289 535 | ||||||
| 2017-02-02 | 2017-01-31 | 4 | Woiwode Thomas | ADVM | Common Stock | D | 3 449 | 37 952 | ||||||
| 2017-01-03 | 2016-12-30 | 4 | Woiwode Thomas | ADVM | Common Stock | D | 3 449 | 34 503 | ||||||
| 2016-12-01 | 2016-11-30 | 4 | Woiwode Thomas | ADVM | Common Stock | D | 3 509 | 31 054 | ||||||
| 2016-11-01 | 2016-10-31 | 4 | Woiwode Thomas | ADVM | Common Stock | D | 3 390 | 27 545 | ||||||
| 2016-07-01 | 2016-05-11 | 4 | Finer Mitchell H. | ADVM | Stock Option (Right to Buy) | D | 4,14 | 44 248 | 44 248 | |||||
| 2016-07-01 | 2016-05-11 | 4 | Finer Mitchell H. | ADVM | Common Stock | D | 24 155 | 580 342 | ||||||
| 2016-07-01 | 2016-05-11 | 4 | Woiwode Thomas | ADVM | Stock Option (Right to Buy) | D | 4,14 | 44 248 | 44 248 | |||||
| 2016-07-01 | 2016-05-11 | 4 | Woiwode Thomas | ADVM | Common Stock | D | 24 155 | 24 155 | ||||||
| 2016-06-21 | 2016-06-17 | 4 | Barone Samuel B. | ADVM | Stock Option (Right to Buy) | D | 3,31 | 50 000 | 50 000 | |||||
| 2016-06-21 | 2016-06-17 | 4 | Barone Samuel B. | ADVM | Common Stock | D | 20 000 | 114 335 | ||||||
| 2016-06-16 | 2016-06-15 | 4 | PATTERSON LEONE D | ADVM | Stock Option (Right to Buy) | D | 3,44 | 200 000 | 200 000 | |||||
| 2016-06-16 | 2016-06-15 | 4 | PATTERSON LEONE D | ADVM | Common Stock | D | 100 000 | 100 000 | ||||||
| 2016-05-20 | 3 | Finer Mitchell H. | ADVM | Common Stock | D | 1 112 374 | ||||||||
| 2016-05-20 | 3 | Finer Mitchell H. | ADVM | Common Stock | D | 1 112 374 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Side Fund IV, L.P. | ADVM | Common Stock | I | 7 006 068 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Capital IV (Switzerland) GmbH | ADVM | Common Stock | I | 13 664 873 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Venture Capital IV, L.P. | ADVM | Common Stock | I | 7 344 627 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Side Fund IV, L.P. | ADVM | Common Stock | I | 7 006 068 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Capital IV (Switzerland) GmbH | ADVM | Common Stock | I | 13 664 873 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Venture Capital IV, L.P. | ADVM | Common Stock | I | 7 344 627 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Venture Capital IV, L.P. | ADVM | Common Stock | I | 7 344 627 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Side Fund IV, L.P. | ADVM | Common Stock | I | 7 006 068 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Venture Capital IV, L.P. | ADVM | Common Stock | I | 7 344 627 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Side Fund IV, L.P. | ADVM | Common Stock | I | 7 006 068 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Capital IV (Switzerland) GmbH | ADVM | Common Stock | I | 13 664 873 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Venture Capital IV, L.P. | ADVM | Common Stock | I | 7 344 627 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Side Fund IV, L.P. | ADVM | Common Stock | I | 7 006 068 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Capital IV (Switzerland) GmbH | ADVM | Common Stock | I | 13 664 873 | ||||||||
| 2016-05-18 | 3 | Versant Capital IV (Switzerland) GmbH Through Versant Capital IV (Switzerland) GmbH | ADVM | Common Stock | I | 13 664 873 | ||||||||
| 2016-05-13 | 2016-05-11 | 4 | Cleveland Paul B | ADVM | Stock Option (Right to Buy) | D | 4,14 | 381 000 | 381 000 | |||||
| 2016-05-13 | 2016-05-11 | 4 | Salzman Amber | ADVM | Stock Option (Right to Buy) | D | 4,14 | 218 000 | 218 000 | |||||
| 2016-05-13 | 2016-05-11 | 4 | Salzman Amber | ADVM | Stock Option (Right to Buy) | D | 0,21 | 377 890 | 377 890 | |||||
| 2016-05-13 | 2016-05-11 | 4 | Salzman Amber | ADVM | Common Stock | D | 629 766 | 629 766 | ||||||
| 2016-05-13 | 2016-05-11 | 4 | Russo Carlo | ADVM | Stock Option (RIght to Buy) | D | 4,14 | 66 000 | 66 000 | |||||
| 2016-05-13 | 2016-05-11 | 4 | Russo Carlo | ADVM | Stock Option (Right to Buy) | D | 0,21 | 715 991 | 715 991 | |||||
| 2016-03-02 | 2016-02-29 | 4 | Wachter Paul | AAVL | Common Stock | D | 3 907 | 31 951 | ||||||
| 2016-02-17 | 2016-02-12 | 4 | MCLAUGHLIN JOHN PETER | AAVL | Stock Option (Right to Buy) | D | 4,80 | 11 905 | 11 905 | |||||
| 2016-02-17 | 2016-02-12 | 4 | MCLAUGHLIN JOHN PETER | AAVL | Common Stock | D | 8 333 | 10 333 | ||||||
| 2016-02-17 | 2016-02-12 | 4 | Wachter Paul | AAVL | Stock Option (Right to Buy) | D | 4,80 | 11 905 | 11 905 | |||||
| 2016-02-17 | 2016-02-12 | 4 | Wachter Paul | AAVL | Common Stock | D | 8 333 | 28 044 | ||||||
| 2016-02-17 | 2016-02-12 | 4 | Blumenkranz Mark S. | AAVL | Stock Option (Right to Buy) | D | 4,80 | 11 905 | 11 905 | |||||
| 2016-02-17 | 2016-02-12 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 8 333 | 531 322 | ||||||
| 2016-02-17 | 2016-02-12 | 4 | Gasmi Mehdi | AAVL | Stock Option (Right to Buy) | D | 4,80 | 188 000 | 188 000 | |||||
| 2016-02-17 | 2016-02-12 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 125 000 | 161 803 | ||||||
| 2016-02-17 | 2016-02-12 | 4 | Barone Samuel B. | AAVL | Stock Option (Right to Buy) | D | 4,80 | 75 000 | 75 000 | |||||
| 2016-02-17 | 2016-02-12 | 4 | Barone Samuel B. | AAVL | Common Stock | D | 50 000 | 91 603 | ||||||
| 2016-02-17 | 2016-02-12 | 4 | Schwartz Steven Daniel | AAVL | Stock Option (Right to Buy) | D | 4,80 | 11 905 | 11 905 | |||||
| 2016-02-17 | 2016-02-12 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 8 333 | 376 264 | ||||||
| 2016-02-17 | 2016-02-12 | 4 | Rubio Roman G. | AAVL | Stock Option (Right to Buy) | D | 4,80 | 75 000 | 75 000 | |||||
| 2016-02-17 | 2016-02-12 | 4 | Rubio Roman G. | AAVL | Common Stock | D | 50 000 | 165 650 | ||||||
| 2016-02-17 | 2016-02-12 | 4 | Braun Shirley | AAVL | Common Stock | D | 116 900 | 161 140 | ||||||
| 2016-02-17 | 2016-02-12 | 4 | Swartzburg Michael | AAVL | Common Stock | D | 36 900 | 82 113 | ||||||
| 2016-02-01 | 2016-01-29 | 4 | Wachter Paul | AAVL | Common Stock | D | 3 334 | 19 711 | ||||||
| 2016-01-04 | 2015-12-31 | 4 | Wachter Paul | AAVL | Common Stock | D | 2 101 | 16 377 | ||||||
| 2015-12-14 | 3 | Swartzburg Michael | AAVL | Common Stock | D | 90 426 | ||||||||
| 2015-12-14 | 3 | Swartzburg Michael | AAVL | Common Stock | D | 90 426 | ||||||||
| 2015-12-11 | 2015-12-09 | 4 | Cleveland Paul B | AAVL | Stock Option (Right to Buy) | D | 9,04 | 910 000 | 910 000 | |||||
| 2015-12-02 | 2015-11-30 | 4 | Wachter Paul | AAVL | Common Stock | D | 1 909 | 14 276 | ||||||
| 2015-11-02 | 2015-10-30 | 4 | Wachter Paul | AAVL | Common Stock | D | 2 373 | 12 367 | ||||||
| 2015-10-02 | 2015-09-30 | 4 | Wachter Paul | AAVL | Common Stock | D | 2 428 | 9 994 | ||||||
| 2015-09-23 | 3 | Braun Shirley | AAVL | Common Stock | D | 81 480 | ||||||||
| 2015-09-23 | 3 | Braun Shirley | AAVL | Common Stock | D | 81 480 | ||||||||
| 2015-09-23 | 2015-09-21 | 4 | Braun Shirley | AAVL | Common Stock | D | 3 500 | 44 240 | ||||||
| 2015-09-11 | 2015-09-09 | 4 | Wachter Paul | AAVL | Common Stock | D | 5 566 | 7 566 | ||||||
| 2015-08-25 | 2015-08-21 | 4 | Hull Hans | AAVL | Common Stock | D | 117 590 | 137 210 | ||||||
| 2015-08-25 | 2015-08-21 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 29 160 | 36 160 | ||||||
| 2015-08-25 | 2015-08-21 | 4 | Barone Samuel B. | AAVL | Common Stock | D | 33 960 | 40 960 | ||||||
| 2015-08-25 | 2015-08-21 | 4 | Rubio Roman G. | AAVL | Common Stock | D | 108 650 | 115 650 | ||||||
| 2015-08-25 | 2015-08-21 | 4 | Bain Linda | AAVL | Common Stock | D | 32 930 | 41 930 | ||||||
| 2015-06-17 | 2015-06-15 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 39,8620 | −1 192 | −48 | 37 161 | ||||
| 2015-06-17 | 2015-06-15 | 4 | Gasmi Mehdi | [AAVL] | Stock Option (Right to Buy) | D | 2,75 | −500 | 95 000 | |||||
| 2015-06-17 | 2015-06-15 | 4 | Gasmi Mehdi | [AAVL] | Common Stock | D | 39,8620 | −500 | −20 | 7 000 | ||||
| 2015-06-17 | 2015-06-15 | 4 | Gasmi Mehdi | [AAVL] | Common Stock | D | 2,7500 | 500 | 1 | 7 500 | ||||
| 2015-06-17 | 2015-06-15 | 4 | Schwartz Steven Daniel | [AAVL] | Common Stock | D | 39,8620 | −16 875 | −673 | 367 931 | ||||
| 2015-06-16 | 2015-06-12 | 4 | Hull Hans | AAVL | Stock Option (Right to Buy) | D | 0,19 | −8 300 | 12 200 | |||||
| 2015-06-16 | 2015-06-12 | 4 | Hull Hans | AAVL | Common Stock | D | 0,1900 | 8 300 | 2 | 19 620 | ||||
| 2015-06-15 | 2015-06-12 | 4 | Bain Linda | [AAVL] | Stock Option (Right to Buy) | D | 3,15 | −3 500 | 233 000 | |||||
| 2015-06-15 | 2015-06-12 | 4 | Bain Linda | [AAVL] | Common Stock | D | 39,9414 | −3 500 | −140 | 9 000 | ||||
| 2015-06-15 | 2015-06-12 | 4 | Bain Linda | [AAVL] | Common Stock | D | 3,1500 | 3 500 | 11 | 12 500 | ||||
| 2015-06-15 | 2015-06-11 | 4 | Blumenkranz Mark S. | [AAVL] | Common Stock | D | 39,9680 | −1 900 | −76 | 522 989 | ||||
| 2015-06-11 | 2015-06-10 | 4 | Blumenkranz Mark S. | [AAVL] | Common Stock | D | 39,9133 | −600 | −24 | 524 889 | ||||
| 2015-06-11 | 2015-06-09 | 4 | Blumenkranz Mark S. | [AAVL] | Common Stock | D | 37,3500 | −200 | −7 | 525 489 | ||||
| 2015-06-11 | 2015-06-09 | 4 | Blumenkranz Mark S. | [AAVL] | Common Stock | D | 36,2003 | −7 000 | −253 | 525 689 | ||||
| 2015-06-11 | 2015-06-09 | 4 | Blumenkranz Mark S. | [AAVL] | Common Stock | D | 35,5200 | −15 300 | −543 | 532 689 | ||||
| 2015-06-11 | 2015-06-10 | 4 | Chalberg Thomas W. | [AAVL] | Common Stock | D | 38,9025 | −6 995 | −272 | 258 988 | ||||
| 2015-06-11 | 2015-06-10 | 4 | Chalberg Thomas W. | [AAVL] | Common Stock | D | 38,0369 | −12 970 | −493 | 265 983 | ||||
| 2015-06-11 | 2015-06-10 | 4 | Chalberg Thomas W. | [AAVL] | Common Stock | D | 36,8883 | −5 035 | −186 | 278 953 | ||||
| 2015-06-10 | 2015-06-08 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 39,8833 | −176 | −7 | 38 353 | ||||
| 2015-06-10 | 2015-06-08 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 38,9579 | −475 | −19 | 38 529 | ||||
| 2015-06-10 | 2015-06-08 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 37,9604 | −541 | −21 | 39 004 | ||||
| 2015-06-10 | 2015-06-08 | 4 | Gasmi Mehdi | [AAVL] | Stock Option (Right to Buy) | D | 2,75 | −500 | 95 500 | |||||
| 2015-06-10 | 2015-06-08 | 4 | Gasmi Mehdi | [AAVL] | Common Stock | D | 39,8826 | −82 | −3 | 7 000 | ||||
| 2015-06-10 | 2015-06-08 | 4 | Gasmi Mehdi | [AAVL] | Common Stock | D | 38,9505 | −183 | −7 | 7 082 | ||||
| 2015-06-10 | 2015-06-08 | 4 | Gasmi Mehdi | [AAVL] | Common Stock | D | 37,9684 | −235 | −9 | 7 265 | ||||
| 2015-06-10 | 2015-06-08 | 4 | Gasmi Mehdi | [AAVL] | Common Stock | D | 2,7500 | 500 | 1 | 7 500 | ||||
| 2015-06-08 | 2015-06-05 | 4 | Blumenkranz Mark S. | [AAVL] | Common Stock | D | 40,0828 | −5 000 | −200 | 547 989 | ||||
| 2015-06-05 | 2015-05-28 | 4/A | Gasmi Mehdi | AAVL | Stock Option (Right to Buy) | D | 2,75 | −500 | 96 000 | |||||
| 2015-06-05 | 2015-05-28 | 4/A | Gasmi Mehdi | AAVL | Common Stock | D | 38,0180 | −500 | −19 | 7 000 | ||||
| 2015-06-05 | 2015-05-28 | 4/A | Gasmi Mehdi | AAVL | Common Stock | D | 2,7500 | 500 | 1 | 7 500 | ||||
| 2015-06-05 | 2015-06-04 | 4 | Hull Hans | [AAVL] | Stock Option (Right to Buy) | D | 0,19 | −2 000 | 20 500 | |||||
| 2015-06-05 | 2015-06-04 | 4 | Hull Hans | [AAVL] | Common Stock | D | 37,6416 | −2 000 | −75 | 11 320 | ||||
| 2015-06-05 | 2015-06-04 | 4 | Hull Hans | [AAVL] | Common Stock | D | 0,1900 | 2 000 | 0 | 13 320 | ||||
| 2015-06-02 | 2015-06-01 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 36,8103 | −210 | −8 | 39 545 | ||||
| 2015-06-02 | 2015-06-01 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 36,1112 | −982 | −35 | 39 755 | ||||
| 2015-06-02 | 2015-06-01 | 4 | Schwartz Steven Daniel | [AAVL] | Common Stock | D | 36,8102 | −3 093 | −114 | 384 806 | ||||
| 2015-06-02 | 2015-06-01 | 4 | Schwartz Steven Daniel | [AAVL] | Common Stock | D | 36,1086 | −14 157 | −511 | 387 899 | ||||
| 2015-05-29 | 2015-05-28 | 4 | Gasmi Mehdi | [AAVL] | Stock Option (Right to Buy) | D | 2,75 | −500 | 96 000 | |||||
| 2015-05-29 | 2015-05-28 | 4 | Gasmi Mehdi | [AAVL] | Common Stock | D | 38,0180 | −500 | −19 | 7 000 | ||||
| 2015-05-29 | 2015-05-28 | 4 | Gasmi Mehdi | [AAVL] | Common Stock | D | 2,7500 | 500 | 1 | 7 500 | ||||
| 2015-05-27 | 2015-05-26 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 38,2968 | −102 | −4 | 40 737 | ||||
| 2015-05-27 | 2015-05-26 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 37,5926 | −304 | −11 | 40 839 | ||||
| 2015-05-27 | 2015-05-26 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 36,5173 | −786 | −29 | 41 143 | ||||
| 2015-05-22 | 2015-05-21 | 4 | Gasmi Mehdi | AAVL | Stock Option (Right to Buy) | D | 2,75 | −500 | 96 500 | |||||
| 2015-05-22 | 2015-05-21 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 38,8700 | −500 | −19 | 7 000 | ||||
| 2015-05-22 | 2015-05-21 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 2,7500 | 500 | 1 | 7 500 | ||||
| 2015-05-22 | 2015-05-22 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 38,8843 | −5 196 | −202 | 402 056 | ||||
| 2015-05-22 | 2015-05-22 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 38,1577 | −11 679 | −446 | 407 252 | ||||
| 2015-05-21 | 2015-05-19 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 36,9112 | −1 000 | −37 | 10 531 | ||||
| 2015-05-21 | 2015-05-19 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 36,9112 | −1 000 | −37 | 1 669 498 | ||||
| 2015-05-21 | 2015-05-19 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 36,9112 | −1 000 | −37 | 10 531 | ||||
| 2015-05-19 | 2015-05-18 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 35,3069 | −1 192 | −42 | 41 929 | ||||
| 2015-05-18 | 2015-05-15 | 4 | Blumenkranz Mark S. | [AAVL] | Common Stock | D | 35,9970 | −4 525 | −163 | 552 989 | ||||
| 2015-05-18 | 2015-05-15 | 4 | Blumenkranz Mark S. | [AAVL] | Common Stock | D | 35,3639 | −17 975 | −636 | 557 514 | ||||
| 2015-05-15 | 2015-05-14 | 4 | Gasmi Mehdi | [AAVL] | Stock Option (Right to Buy) | D | 2,75 | −500 | 97 000 | |||||
| 2015-05-15 | 2015-05-14 | 4 | Gasmi Mehdi | [AAVL] | Common Stock | D | 35,3125 | −500 | −18 | 7 000 | ||||
| 2015-05-15 | 2015-05-14 | 4 | Gasmi Mehdi | [AAVL] | Common Stock | D | 2,7500 | 500 | 1 | 7 500 | ||||
| 2015-05-13 | 2015-05-13 | 4 | Bain Linda | [AAVL] | Stock Option (Right to Buy) | D | 3,15 | −285 | 236 500 | |||||
| 2015-05-13 | 2015-05-13 | 4 | Bain Linda | [AAVL] | Common Stock | D | 34,9429 | −285 | −10 | 9 000 | ||||
| 2015-05-13 | 2015-05-13 | 4 | Bain Linda | [AAVL] | Common Stock | D | 3,1500 | 285 | 1 | 9 285 | ||||
| 2015-05-13 | 2015-05-13 | 4 | Blumenkranz Mark S. | [AAVL] | Common Stock | D | 34,9429 | −715 | −25 | 575 489 | ||||
| 2015-05-12 | 2015-05-11 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 34,2939 | −132 | −5 | 43 121 | ||||
| 2015-05-12 | 2015-05-11 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 33,7028 | −552 | −19 | 43 253 | ||||
| 2015-05-12 | 2015-05-11 | 4 | Wachter Paul | [AAVL] | Common Stock | I | 32,7987 | −508 | −17 | 43 805 | ||||
| 2015-05-12 | 2015-05-11 | 4 | Bain Linda | [AAVL] | Stock Option (Right to Buy) | D | 3,15 | −715 | 236 785 | |||||
| 2015-05-12 | 2015-05-11 | 4 | Bain Linda | [AAVL] | Common Stock | D | 34,9146 | −715 | −25 | 9 000 | ||||
| 2015-05-12 | 2015-05-11 | 4 | Bain Linda | [AAVL] | Common Stock | D | 3,1500 | 715 | 2 | 9 715 | ||||
| 2015-05-12 | 2015-05-11 | 4 | Blumenkranz Mark S. | [AAVL] | Common Stock | D | 34,9146 | −1 785 | −62 | 576 204 | ||||
| 2015-05-11 | 2015-05-08 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 33,0488 | −17 250 | −570 | 418 931 | ||||
| 2015-05-08 | 2015-05-07 | 4 | Gasmi Mehdi | AAVL | Stock Option (Right to Buy) | D | 2,75 | −500 | 97 500 | |||||
| 2015-05-08 | 2015-05-07 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 33,2763 | −500 | −17 | 7 000 | ||||
| 2015-05-08 | 2015-05-07 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 2,7500 | 500 | 1 | 7 500 | ||||
| 2015-05-07 | 2015-05-05 | 4 | Chalberg Thomas W. | AAVL | Common Stock | D | 30,0037 | −25 000 | −750 | 283 988 | ||||
| 2015-05-06 | 2015-05-04 | 4 | Wachter Paul | AAVL | Common Stock | I | 30,8698 | −1 192 | −37 | 44 313 | ||||
| 2015-05-06 | 2015-05-04 | 4 | Bain Linda | AAVL | Stock Option (Right to Buy) | D | 3,15 | −2 500 | 237 500 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Bain Linda | AAVL | Common Stock | D | 31,5888 | −2 500 | −79 | 9 000 | ||||
| 2015-05-06 | 2015-05-04 | 4 | Bain Linda | AAVL | Common Stock | D | 3,1500 | 2 500 | 8 | 11 500 | ||||
| 2015-05-06 | 2015-05-04 | 4 | Hull Hans | AAVL | Stock Option (Right to Buy) | D | 0,19 | −5 000 | 22 500 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Hull Hans | AAVL | Common Stock | D | 30,8698 | −5 000 | −154 | 11 320 | ||||
| 2015-05-06 | 2015-05-04 | 4 | Hull Hans | AAVL | Common Stock | D | 0,1900 | 5 000 | 1 | 16 320 | ||||
| 2015-05-05 | 2015-05-01 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 32,3653 | −20 000 | −647 | 577 989 | ||||
| 2015-04-30 | 2015-04-28 | 4 | Gasmi Mehdi | AAVL | Stock Option (Right to Buy) | D | 2,75 | −1 000 | 98 000 | |||||
| 2015-04-30 | 2015-04-28 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 35,6670 | −1 000 | −36 | 7 000 | ||||
| 2015-04-30 | 2015-04-28 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 2,7500 | 1 000 | 3 | 8 000 | ||||
| 2015-04-29 | 2015-04-27 | 4 | Wachter Paul | AAVL | Common Stock | I | 35,6066 | −1 192 | −42 | 45 505 | ||||
| 2015-04-23 | 2015-04-21 | 4 | MCLAUGHLIN JOHN PETER | AAVL | Stock Option (Right to Buy) | D | 39,35 | 7 000 | 7 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | MCLAUGHLIN JOHN PETER | AAVL | Common Stock | D | 2 000 | 2 000 | ||||||
| 2015-04-23 | 2015-04-21 | 4 | Wachter Paul | AAVL | Stock Option (Right to Buy) | D | 39,35 | 7 000 | 7 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | Wachter Paul | AAVL | Common Stock | D | 2 000 | 2 000 | ||||||
| 2015-04-23 | 2015-04-21 | 4 | Bain Linda | AAVL | Stock Option (Right to Buy) | D | 39,35 | 25 000 | 25 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | Bain Linda | AAVL | Common Stock | D | 9 000 | 9 000 | ||||||
| 2015-04-23 | 2015-04-21 | 4 | Blumenkranz Mark S. | AAVL | Stock Option (Right to Buy) | D | 39,35 | 7 000 | 7 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 2 000 | 597 989 | ||||||
| 2015-04-23 | 2015-04-21 | 4 | Chalberg Thomas W. | AAVL | Stock Option (Right to Buy) | D | 39,35 | 67 000 | 67 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | Chalberg Thomas W. | AAVL | Common Stock | D | 23 000 | 308 988 | ||||||
| 2015-04-23 | 2015-04-21 | 4 | Gasmi Mehdi | AAVL | Stock Option (Right to Buy) | D | 39,35 | 20 000 | 20 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | Gasmi Mehdi | AAVL | Stock Option (Right to Buy) | D | 2,75 | −1 000 | 99 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 7 000 | 7 000 | ||||||
| 2015-04-23 | 2015-04-21 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 39,2114 | −1 000 | −39 | 0 | ||||
| 2015-04-23 | 2015-04-21 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 2,7500 | 1 000 | 3 | 1 000 | ||||
| 2015-04-23 | 2015-04-21 | 4 | Hull Hans | AAVL | Stock Option (Right to Buy) | D | 39,35 | 23 000 | 23 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | Hull Hans | AAVL | Common Stock | D | 8 000 | 11 320 | ||||||
| 2015-04-23 | 2015-04-21 | 4 | Barone Samuel B. | AAVL | Stock Option (Right to Buy) | D | 39,35 | 20 000 | 20 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | Barone Samuel B. | AAVL | Common Stock | D | 7 000 | 7 000 | ||||||
| 2015-04-23 | 2015-04-21 | 4 | Schwartz Steven Daniel | AAVL | Stock Option (Right to Buy) | D | 39,35 | 7 000 | 7 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 2 000 | 453 056 | ||||||
| 2015-04-23 | 2015-04-23 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 38,6172 | −16 875 | −652 | 436 181 | ||||
| 2015-04-23 | 2015-04-21 | 4 | Rubio Roman G. | AAVL | Stock Option (Right to Buy) | D | 39,35 | 20 000 | 20 000 | |||||
| 2015-04-23 | 2015-04-21 | 4 | Rubio Roman G. | AAVL | Common Stock | D | 7 000 | 7 000 | ||||||
| 2015-04-21 | 2015-04-20 | 4 | Wachter Paul | AAVL | Common Stock | I | 40,1927 | −1 192 | −48 | 46 697 | ||||
| 2015-04-20 | 2015-04-16 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 42,0400 | −200 | −8 | 595 989 | ||||
| 2015-04-20 | 2015-04-16 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 41,5865 | −24 800 | −1 031 | 596 189 | ||||
| 2015-04-15 | 2015-04-13 | 4 | Wachter Paul | AAVL | Common Stock | I | 40,7400 | −24 | −1 | 47 889 | ||||
| 2015-04-15 | 2015-04-13 | 4 | Wachter Paul | AAVL | Common Stock | I | 39,8475 | −338 | −13 | 47 913 | ||||
| 2015-04-15 | 2015-04-13 | 4 | Wachter Paul | AAVL | Common Stock | I | 39,0958 | −830 | −32 | 48 251 | ||||
| 2015-04-15 | 2015-04-14 | 4 | Gasmi Mehdi | AAVL | Stock Option (Right to Buy) | D | 2,75 | −1 000 | 100 000 | |||||
| 2015-04-15 | 2015-04-14 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 39,4480 | −1 000 | −39 | 0 | ||||
| 2015-04-15 | 2015-04-14 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 2,7500 | 1 000 | 3 | 1 000 | ||||
| 2015-04-15 | 2015-04-14 | 4 | Zygtech, LLC | AAVL | Common Stock | D | 39,9268 | −4 600 | −184 | 2 438 176 | ||||
| 2015-04-15 | 2015-04-13 | 4 | Zygtech, LLC | AAVL | Common Stock | D | 40,6942 | −776 | −32 | 2 442 776 | ||||
| 2015-04-15 | 2015-04-13 | 4 | Zygtech, LLC | AAVL | Common Stock | D | 39,9438 | −7 350 | −294 | 2 443 552 | ||||
| 2015-04-15 | 2015-04-13 | 4 | Zygtech, LLC | AAVL | Common Stock | D | 39,0943 | −12 274 | −480 | 2 450 902 | ||||
| 2015-04-13 | 2015-04-09 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 40,3779 | −200 | −8 | 451 056 | ||||
| 2015-04-13 | 2015-04-09 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 39,7186 | −17 050 | −677 | 451 256 | ||||
| 2015-04-08 | 2015-04-08 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 39,9363 | −2 500 | −100 | 620 989 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 39,0608 | −32 | −1 | 11 531 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 39,0608 | −32 | −1 | 11 531 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 39,0608 | −32 | −1 | 11 531 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 38,5875 | −968 | −37 | 11 563 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 38,5875 | −968 | −37 | 11 563 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 38,5875 | −968 | −37 | 11 563 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 39,0603 | −726 | −28 | 623 489 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 38,5874 | −21 774 | −840 | 624 215 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Gasmi Mehdi | AAVL | Stock Option (Right to Buy) | D | 2,75 | −9 000 | 101 000 | |||||
| 2015-04-08 | 2015-04-07 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 39,0603 | −292 | −11 | 0 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 38,5874 | −8 708 | −336 | 292 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Gasmi Mehdi | AAVL | Common Stock | D | 2,7500 | 9 000 | 25 | 9 000 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Hull Hans | AAVL | Stock Option (Right to Buy) | D | 0,19 | −27 500 | 27 500 | |||||
| 2015-04-08 | 2015-04-07 | 4 | Hull Hans | AAVL | Common Stock | D | 39,0603 | −887 | −35 | 3 320 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Hull Hans | AAVL | Common Stock | D | 38,5874 | −26 613 | −1 027 | 4 207 | ||||
| 2015-04-08 | 2015-04-07 | 4 | Hull Hans | AAVL | Common Stock | D | 0,1900 | 27 500 | 5 | 30 820 | ||||
| 2015-01-15 | 2015-01-13 | 4 | Chalberg Thomas W. | AAVL | Common Stock | D | 55,4600 | −85 000 | −4 714 | 285 988 | ||||
| 2015-01-15 | 2015-01-13 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 55,4600 | −100 000 | −5 546 | 645 989 | ||||
| 2015-01-15 | 2015-01-13 | 4 | Wachter Paul | AAVL | Common Stock | I | 55,4600 | −14 000 | −776 | 49 081 | ||||
| 2015-01-15 | 2015-01-13 | 4 | Zygtech, LLC | AAVL | Common Stock | D | 55,4600 | −100 000 | −5 546 | 2 463 176 | ||||
| 2015-01-15 | 2015-01-13 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 55,4600 | −91 000 | −5 047 | 468 306 | ||||
| 2015-01-14 | 2014-12-12 | 4 | Chalberg Thomas W. | AAVL | Stock Option (Right to Buy) | D | 0,21 | −413 | 159 587 | |||||
| 2015-01-14 | 2014-12-12 | 4 | Chalberg Thomas W. | AAVL | Common Stock | I | 413 | 413 | ||||||
| 2015-01-14 | 2014-12-12 | 4 | Chalberg Thomas W. | AAVL | Common Stock | D | −413 | 370 988 | ||||||
| 2015-01-14 | 2014-12-12 | 4 | Chalberg Thomas W. | AAVL | Common Stock | D | 0,2100 | 413 | 0 | 371 401 | ||||
| 2014-11-14 | 2014-10-03 | 4 | Rubio Roman G. | AAVL | Stock Option (Right to Buy) | D | 33,70 | 180 000 | 180 000 | |||||
| 2014-08-07 | 3/A | Blumenkranz Mark S. | AAVL | Common Stock | D | 700 000 | ||||||||
| 2014-08-07 | 3/A | Schwartz Steven Daniel | AAVL | Common Stock | D | 500 000 | ||||||||
| 2014-08-07 | 2014-08-05 | 4 | MCLAUGHLIN JOHN PETER | AAVL | Series B Preferred Stock | I | −13 280 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | MCLAUGHLIN JOHN PETER | AAVL | Series B Preferred Stock | I | −13 280 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | MCLAUGHLIN JOHN PETER | AAVL | Common Stock | I | 13 280 | 13 280 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | MCLAUGHLIN JOHN PETER | AAVL | Common Stock | I | 13 280 | 13 280 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Wachter Paul | AAVL | Series B Preferred Stock | I | −63 081 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Wachter Paul | AAVL | Common Stock | I | 63 081 | 63 081 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock | I | −12 531 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock | I | −12 531 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock | I | 1,4500 | 4 137 | 6 | 12 531 | ||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock | I | 1,4500 | 4 137 | 6 | 12 531 | ||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock Purchase Warrant | I | 1,45 | −4 137 | 0 | |||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock Purchase Warrant | I | 1,45 | −4 137 | 0 | |||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock | I | −12 531 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock | I | 1,4500 | 4 137 | 6 | 12 531 | ||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock Purchase Warrant | I | 1,45 | −4 137 | 0 | |||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock | D | −20 989 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock | D | 1,4500 | 5 689 | 8 | 20 989 | ||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Series A Preferred Stock Purchase Warrant | D | 1,45 | −5 689 | 0 | |||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Common Stock Purchase Warrant | D | 0,15 | −25 000 | 0 | |||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 12 531 | 12 531 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 12 531 | 12 531 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | I | 12 531 | 12 531 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 20 989 | 745 989 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Blumenkranz Mark S. | AAVL | Common Stock | D | 0,1500 | 25 000 | 4 | 725 000 | ||||
| 2014-08-07 | 2014-08-05 | 4 | Chalberg Thomas W. | AAVL | Series A Preferred Stock | D | −10 988 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Chalberg Thomas W. | AAVL | Series A Preferred Stock | D | 1,4500 | 3 102 | 4 | 10 988 | ||||
| 2014-08-07 | 2014-08-05 | 4 | Chalberg Thomas W. | AAVL | Series A Preferred Stock Purchase Warrant | D | 1,45 | −3 102 | 0 | |||||
| 2014-08-07 | 2014-08-05 | 4 | Chalberg Thomas W. | AAVL | Common Stock | D | 10 988 | 370 988 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Hull Hans | AAVL | Series B Preferred Stock | D | −3 320 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Hull Hans | AAVL | Common Stock | D | 3 320 | 3 320 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Zygtech, LLC | AAVL | Series B Preferred Stock | D | −295 115 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Zygtech, LLC | AAVL | Series A Preferred Stock | D | −2 799 269 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Zygtech, LLC | AAVL | Common Stock | D | 295 115 | 3 094 384 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Zygtech, LLC | AAVL | Common Stock | D | 2 799 269 | 2 799 269 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Schwartz Steven Daniel | AAVL | Series A Preferred Stock | D | −25 306 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Schwartz Steven Daniel | AAVL | Series A Preferred Stock | D | 1,4500 | 6 620 | 10 | 25 306 | ||||
| 2014-08-07 | 2014-08-05 | 4 | Schwartz Steven Daniel | AAVL | Series A Preferred Stock Purchase Warrant | D | 1,45 | −6 620 | 0 | |||||
| 2014-08-07 | 2014-08-05 | 4 | Schwartz Steven Daniel | AAVL | Common Stock Purchase Warrant | D | 0,15 | −34 000 | 0 | |||||
| 2014-08-07 | 2014-08-05 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 25 306 | 559 306 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Schwartz Steven Daniel | AAVL | Common Stock | D | 0,1500 | 34 000 | 5 | 534 000 | ||||
| 2014-08-07 | 2014-08-05 | 4 | Venrock Associates VI, L.P. By Funds | AAVL | Series B Preferred Stock | I | −1 965 471 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Venrock Associates VI, L.P. By Funds | AAVL | Common Stock | I | 17,0000 | 400 000 | 6 800 | 2 365 471 | ||||
| 2014-08-07 | 2014-08-05 | 4 | Venrock Associates VI, L.P. By Funds | AAVL | Common Stock | I | 1 965 471 | 1 965 471 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Venrock Healthcare Capital Partners II, L.P. By Funds | AAVL | Series B Preferred Stock | I | −1 965 471 | 0 | ||||||
| 2014-08-07 | 2014-08-05 | 4 | Venrock Healthcare Capital Partners II, L.P. By Funds | AAVL | Common Stock | I | 17,0000 | 400 000 | 6 800 | 2 365 471 | ||||
| 2014-08-07 | 2014-08-05 | 4 | Venrock Healthcare Capital Partners II, L.P. By Funds | AAVL | Common Stock | I | 1 965 471 | 1 965 471 | ||||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | AAVL | Series B Preferred Stock | I | −531 208 | 0 | ||||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | AAVL | Series B Preferred Stock | I | −147 410 | 0 | ||||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | AAVL | Series B Preferred Stock | I | −184 594 | 0 | ||||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield International Master Fund, L.P. | AAVL | Common Stock | I | 24,5700 | 31 650 | 778 | 627 267 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield International Master Fund, L.P. | AAVL | Common Stock | I | 26,3500 | 49 981 | 1 317 | 595 617 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield International Master Fund, L.P. | AAVL | Common Stock | I | 26,1400 | 27 600 | 721 | 545 636 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield International Master Fund, L.P. | AAVL | Common Stock | I | 27,5400 | 12 400 | 341 | 518 036 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield International Master Fund, L.P. | AAVL | Common Stock | I | 26,4200 | 219 864 | 5 809 | 505 636 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield International Master Fund, L.P. | AAVL | Common Stock | I | 25,7900 | 18 700 | 482 | 285 772 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield International Master Fund, L.P. | AAVL | Common Stock | I | 25,5200 | 9 800 | 250 | 267 072 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield International Master Fund, L.P. | AAVL | Common Stock | I | 25,4100 | 201 972 | 5 132 | 257 272 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield International Master Fund, L.P. | AAVL | Common Stock | I | 17,0000 | 55 300 | 940 | 55 300 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Partners, L.P. | AAVL | Common Stock | I | 24,5700 | 25 600 | 629 | 507 200 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Partners, L.P. | AAVL | Common Stock | I | 26,3500 | 40 400 | 1 065 | 481 600 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Partners, L.P. | AAVL | Common Stock | I | 26,1400 | 22 400 | 586 | 441 200 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Partners, L.P. | AAVL | Common Stock | I | 27,5400 | 10 100 | 278 | 418 800 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Partners, L.P. | AAVL | Common Stock | I | 26,4200 | 177 700 | 4 695 | 408 700 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Partners, L.P. | AAVL | Common Stock | I | 25,7900 | 15 100 | 389 | 231 000 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Partners, L.P. | AAVL | Common Stock | I | 25,5200 | 7 900 | 202 | 215 900 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Partners, L.P. | AAVL | Common Stock | I | 25,4100 | 163 300 | 4 149 | 208 000 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Partners, L.P. | AAVL | Common Stock | I | 17,0000 | 44 700 | 760 | 44 700 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | AAVL | Common Stock | I | 17,0000 | 123 077 | 2 092 | 654 285 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | AAVL | Common Stock | I | 17,0000 | 34 223 | 582 | 181 633 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | AAVL | Common Stock | I | 17,0000 | 42 700 | 726 | 227 294 | ||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | AAVL | Common Stock | I | 531 208 | 531 208 | ||||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | AAVL | Common Stock | I | 147 410 | 147 410 | ||||||
| 2014-08-05 | 2014-08-05 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | AAVL | Common Stock | I | 184 594 | 184 594 | ||||||
| 2014-08-05 | 2014-08-05 | 4 | REGENERON PHARMACEUTICALS INC | AAVL | Series B Preferred Stock | D | −531 208 | 0 | ||||||
| 2014-08-05 | 2014-08-05 | 4 | REGENERON PHARMACEUTICALS INC | AAVL | Series A Preferred Stock | D | −689 655 | 0 | ||||||
| 2014-08-05 | 2014-08-05 | 4 | REGENERON PHARMACEUTICALS INC | AAVL | Common Stock | D | 17,0000 | 588 235 | 10 000 | 1 809 098 | ||||
| 2014-08-05 | 2014-08-05 | 4 | REGENERON PHARMACEUTICALS INC | AAVL | Common Stock | D | 531 208 | 1 220 863 | ||||||
| 2014-08-05 | 2014-08-05 | 4 | REGENERON PHARMACEUTICALS INC | AAVL | Common Stock | D | 689 655 | 689 655 | ||||||
| 2014-08-01 | 2014-07-30 | 4 | MCLAUGHLIN JOHN PETER | AAVL | Stock Option (Right to Buy) | D | 17,00 | 75 000 | 75 000 | |||||
| 2014-08-01 | 2014-07-30 | 4 | Wachter Paul | AAVL | Stock Option (Right to Buy) | D | 17,00 | 75 000 | 75 000 | |||||
| 2014-08-01 | 2014-07-30 | 4 | Chalberg Thomas W. | AAVL | Stock Option (Right to Buy) | D | 17,00 | 80 000 | 80 000 | |||||
| 2014-08-01 | 2014-07-30 | 4 | Gasmi Mehdi | AAVL | Stock Option (Right to Buy) | D | 17,00 | 70 000 | 70 000 | |||||
| 2014-08-01 | 2014-07-30 | 4 | Hull Hans | AAVL | Stock Option (Right to Buy) | D | 17,00 | 75 000 | 75 000 | |||||
| 2014-07-30 | 3 | Blumenkranz Mark S. | AAVL | Common Stock | D | 1 450 000 | ||||||||
| 2014-07-30 | 3 | Blumenkranz Mark S. | AAVL | Common Stock | D | 1 450 000 | ||||||||
| 2014-07-30 | 3 | Chalberg Thomas W. | AAVL | Common Stock | D | 1 560 000 | ||||||||
| 2014-07-30 | 3 | Chalberg Thomas W. | AAVL | Common Stock | I | 1 620 000 | ||||||||
| 2014-07-30 | 3 | Chalberg Thomas W. | AAVL | Common Stock | I | 1 620 000 | ||||||||
| 2014-07-30 | 3 | Chalberg Thomas W. | AAVL | Common Stock | D | 1 560 000 | ||||||||
| 2014-07-30 | 3 | Chalberg Thomas W. | AAVL | Common Stock | I | 1 620 000 | ||||||||
| 2014-07-30 | 3 | Chalberg Thomas W. | AAVL | Common Stock | I | 1 620 000 | ||||||||
| 2014-07-30 | 3 | Schwartz Steven Daniel | AAVL | Common Stock | D | 1 068 000 | ||||||||
| 2014-07-30 | 3 | Schwartz Steven Daniel | AAVL | Common Stock | D | 1 068 000 |
P
Köp på öppna marknaden eller privat köp av icke-derivatsäkerhet
S
Köp på öppna marknaden eller privat försäljning av icke-derivatsäkerhet
A
Bevilja, tilldelning eller annat förvärv av värdepapper från företaget (såsom en option)
C
Omvandling av derivat
D
Försäljning eller överföring av värdepapper tillbaka til företaget
F
Betalning av lösenpris eller skatteskuld med del av värdepapper som erhållits från bolaget
G
Överlåtelse av värdepapper från eller till insidern
K
Aktieswappar och liknande säkringsaffärer
M
Utövande eller omvandling av derivatsäkerhet som erhållits från företaget (som en option)
V
En transaktion friviligt rapporterad på schema 4
J
Andra (med en fotnot som beskriver transaktionen)
