Ionis Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US4622221004

Introduktion

Den här sidan ger en omfattande analys av den kända insiderhandelshistoriken för Stanley T Crooke. Insiders är tjänstemän, styrelseledamöter eller betydande investerare i ett företag. Det är olagligt för insiders att göra affärer i sina företag baserat på specifik, icke-offentlig information. Detta betyder inte att det är olagligt för dem att göra några affärer i sina egna företag. De måste dock rapportera alla affärer till SEC via ett formulär 4. Trots dessa restriktioner tyder akademisk forskning på att insiders – i allmänhet – tenderar att överträffa marknaden i sina egna företag.

Genomsnittlig handelslönsamhet

Den genomsnittliga handelslönsamheten är den genomsnittliga avkastningen av alla köp på den öppna marknaden som insidern gjort under de senaste tre åren. För att beräkna detta undersöker vi alla oplanerade köp på öppen marknad som görs av insidern, exklusive alla affärer som markerats som en del av en 10b5-1-handelsplan. Vi beräknar sedan den genomsnittliga prestandan för dessa affärer under 3, 6 och 12 månader, med ett genomsnitt av var och en av dessa varaktigheter för att generera ett slutgiltigt resultatmått för varje affär. Slutligen tar vi ett genomsnitt av alla prestationsmått för att beräkna ett prestationsmått för insidern. Denna lista inkluderar endast insiders som har gjort minst tre affärer under de senaste två åren.

Om lönsamheten för denna insiderhandel är "N/A", så har insidern antingen inte gjort några köp på den öppna marknaden under de senaste tre åren, eller så är affärerna de har gjort för nya för att kunna beräkna ett tillförlitligt resultatmått.

Uppdateringsfrekvens: Dagligen

Se listan över mest lönsamma insiderhandlare

Företag med rapporterade insiderpositioner

SEC-anmälningarna visar att Stanley T Crooke har rapporterat innehav eller affärer i följande företag:

Värdepapper Titel Senaste rapporterade innehav
US:IONS / Ionis Pharmaceuticals, Inc. Exec Chairman of the Board, Director 2 021
Director 0
US:RGLS / Regulus Therapeutics Inc. Director, 10% Owner 25 000
Hur man tolkar diagrammen

Följande diagram visar aktieutvecklingen för värdepapper efter varje icke-planerad handel på öppen marknad som görs av Stanley T Crooke. Icke-planerad handel är affärer som inte gjordes som en del av en 10b5-1-handelsplan. Aktieutvecklingen visas som kumulativ procentuell förändring av aktiekursen. Till exempel, om en insiderhandel gjordes den 1 januari 2019, kommer diagrammet att visa den dagliga procentuella förändringen av värdepapperet fram till idag. Om aktiekursen skulle gå från $10 till $15 under denna tid, skulle den kumulativa procentuella förändringen i aktiekursen vara 50%. En förändring i priset från 10 USD till 20 USD skulle vara 100 % och en prisändring på 10 USD till 5 USD skulle vara -50 %.

I slutändan försöker vi avgöra hur nära insiders affärer korrelerar med överavkastning (positiv eller negativ) i aktiekursen för att se om insidern tar tid för sina affärer att dra nytta av insiderinformation. Tänk på situationen där en insider gjorde detta. I den här situationen förväntar vi oss antingen (a) positiv avkastning efter köp eller (b) negativ avkastning efter försäljning. I fallet med (a) skulle KÖP-diagrammet visa en serie uppåtlutande kurvor, vilket indikerar positiv avkastning efter varje köptransaktion. I fallet med (b) skulle SALE-diagrammet visa en serie nedåtlutande kurvor, vilket indikerar negativ avkastning efter varje försäljningstransaktion.

Detta är dock inte tillräckligt för att dra slutsatser. Om till exempel aktiekursen i bolaget var i en icke-cyklisk stigning under många år, skulle vi förvänta oss att alla tomter efter köpet skulle vara uppåtlutande. Likaså skulle icke-cykliska nedgångar under många år resultera i nedåtlutande post-trade tomter. Inget av dessa diagram skulle tyda på insiderhandel.

Den starkaste indikatorn skulle vara en situation där aktiekursen var extremt cyklisk, och det fanns både positiva signaler i KÖP-diagrammet och negativa plotter på SALE-diagrammet. Denna situation skulle i hög grad tyda på en insider som tog tid för affärer till sin ekonomiska fördel.

Insiderköp IONS / Ionis Pharmaceuticals, Inc. - Analys av kortsiktig vinst

I det här avsnittet analyserar vi lönsamheten för varje oplanerat insiderköp på en öppen marknad som görs i IONS / Ionis Pharmaceuticals, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormal avkastning och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .

Tabellen nedan visar de senaste öppna marknadsköpen som inte var en del av en automatisk handelsplan.

Handelsdatum Ticker Insider Rapporterade
aktier
Rapporterad
pris
Justerade
aktier
Justerat
pris
Kostnadsgrund Dagar till
max
Pris vid
max
Max
vinst ($)
Maximal avkastning (%)
Det finns inga kända oplanerade öppna marknadstransaktioner för denna insider

Det justerade prisetär det justerade priset efter split. Justerade aktier er de split-justerade aktier.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Insiderförsäljning - Analys av kortsiktig förlust

I det här avsnittet analyserar vi det kortsiktiga undvikandet av förluster för varje oplanerad insiderförsäljning på öppen marknad som görs i IONS / Ionis Pharmaceuticals, Inc.. Ett konsekvent mönster för att undvika förluster kan tyda på att framtida försäljningstransaktioner kan förutsäga prisnedgångar. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .

Följande tabell visar de senaste försäljningarna på den öppna marknaden som inte ingick i en automatisk handelsplan.

Handelsdatum Ticker Insider Rapporterade
aktier
Rapporterad
pris
Justerade
aktier
Justerat
pris
Kostnadsgrund Dagar till
min
Pris vid
min
Maximal förlust
undvikits ($)
Maximal förlust
undvikits ($)
2020-03-17 IONS CROOKE STANLEY T 4 579 44,5000 4 579 44,5000 203 766 6 41.6000 −13 279 −6,52
2020-03-17 IONS CROOKE STANLEY T 5 421 44,5000 5 421 44,5000 241 234
2020-03-17 IONS CROOKE STANLEY T 5 651 45,0000 5 651 45,0000 254 295
2020-03-17 IONS CROOKE STANLEY T 4 349 45,0000 4 349 45,0000 195 705
2018-01-15 IONS CROOKE STANLEY T 15 893 51,7600 15 893 51,7600 822 622
2018-01-15 IONS CROOKE STANLEY T 656 51,7600 656 51,7600 33 955
2017-01-17 IONS CROOKE STANLEY T 3 008 46,2890 3 008 46,2890 139 237
2017-01-17 IONS CROOKE STANLEY T 4 236 46,2890 4 236 46,2890 196 080
2017-01-17 IONS CROOKE STANLEY T 3 728 46,2900 3 728 46,2900 172 569
2017-01-17 IONS CROOKE STANLEY T 4 410 46,2900 4 410 46,2900 204 139
2017-01-17 IONS CROOKE STANLEY T 163 46,2910 163 46,2910 7 545
2017-01-17 IONS CROOKE STANLEY T 139 46,2900 139 46,2900 6 434
2017-01-17 IONS CROOKE STANLEY T 142 46,2910 142 46,2910 6 573
2017-01-17 IONS CROOKE STANLEY T 131 46,2900 131 46,2900 6 064
2016-01-19 IONS CROOKE STANLEY T 1 645 41,4582 1 645 41,4582 68 199
2016-01-19 IONS CROOKE STANLEY T 3 065 41,4582 3 065 41,4582 127 069
2016-01-19 IONS CROOKE STANLEY T 4 317 41,4551 4 317 41,4551 178 962
2016-01-19 IONS CROOKE STANLEY T 3 798 41,4655 3 798 41,4655 157 486
2016-01-19 IONS CROOKE STANLEY T 124 41,4610 124 41,4610 5 141
2016-01-19 IONS CROOKE STANLEY T 166 41,4626 166 41,4626 6 883
2016-01-19 IONS CROOKE STANLEY T 141 41,4633 141 41,4633 5 846
2016-01-19 IONS CROOKE STANLEY T 145 41,4600 145 41,4600 6 012
2015-01-16 ISIS CROOKE STANLEY T 1 574 67,9640 1 574 67,9640 106 975
2015-01-16 ISIS CROOKE STANLEY T 2 933 67,9640 2 933 67,9640 199 338
2015-01-16 ISIS CROOKE STANLEY T 4 130 67,9645 4 130 67,9645 280 693
2015-01-16 ISIS CROOKE STANLEY T 121 67,9640 121 67,9640 8 224
2015-01-16 ISIS CROOKE STANLEY T 160 67,9640 160 67,9640 10 874
2015-01-16 ISIS CROOKE STANLEY T 136 67,9640 136 67,9640 9 243
2014-01-16 ISIS CROOKE STANLEY T 2 112 47,0812 2 112 47,0812 99 435
2014-01-16 ISIS CROOKE STANLEY T 1 134 47,0811 1 134 47,0811 53 390
2014-01-16 ISIS CROOKE STANLEY T 160 47,0799 160 47,0799 7 533
2014-01-16 ISIS CROOKE STANLEY T 121 47,0807 121 47,0807 5 697
2013-04-23 ISIS CROOKE STANLEY T 30 000 22,0967 30 000 22,0967 662 901
2013-01-16 ISIS CROOKE STANLEY T 1 317 13,9999 1 317 13,9999 18 438
2013-01-16 ISIS CROOKE STANLEY T 143 13,9994 143 13,9994 2 002

Det justerade prisetär det justerade priset efter split. Justerade aktier er de split-justerade aktier.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Insiderhandelshistorik

Den här tabellen visar den fullständiga listan över insideraffärer gjorda av Stanley T Crooke som avslöjats för Securities Exchange Commission (SEC).

Fildatum Transaktionsdatum Schema Ticker Värdepapper Kode 10b5-1 Aktier Återstående aktier Procentuell förandring Aktie
pris
Transaktionsvärde Återstående
värde
2021-01-28 2021-01-26 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −28 333 2 021 −93,34 63,74 −1 805 812 128 809
2021-01-25 2021-01-22 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −40 000 494 391 −7,49 61,68 −2 467 000 30 491 565
2021-01-25 2021-01-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −21 042 534 391 −3,79 61,65 −1 297 239 32 945 205
2021-01-25 2021-01-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −13 958 555 433 −2,45 60,53 −844 878 33 620 359
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −4 371 7 801 −35,91
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −47 257 87 885 −34,97
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 5 333 5 333
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes −1 434 3 111 −31,55 61,28 −87 876 190 642
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4 371 4 545 2 512,07
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes −18 924 30 354 −38,40 61,28 −1 159 663 1 860 093
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 47 257 49 278 2 338,30
2021-01-06 2021-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 12 000 12 000
2021-01-06 2020-11-19 5 IONS IONIS PHARMACEUTICALS INC
Common Stock
G - Gift −31 000 569 391 −5,16
2020-12-17 2020-12-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 407 174 −88,99 50,50 −71 054 8 787
2020-12-17 2020-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −39 000 600 391 −6,10 49,78 −1 941 225 29 884 462
2020-12-09 2020-12-07 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −6 000 639 391 −0,93 51,50 −309 000 32 928 636
2020-12-09 2020-12-07 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 645 391 −0,77 51,87 −259 350 33 476 496
2020-11-30 2020-11-25 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
M - Exercise −12 990 0 −100,00
2020-11-30 2020-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −12 990 2 021 −86,54 50,05 −650 150 101 151
2020-11-30 2020-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 12 990 15 011 642,75 39,87 517 911 598 489
2020-11-25 2020-11-24 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
M - Exercise −2 590 12 990 −16,62
2020-11-25 2020-11-24 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 590 2 021 −56,17 50,83 −131 650 102 727
2020-11-25 2020-11-24 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2 590 4 611 128,15 39,87 103 263 183 841
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
M - Exercise −11 600 15 580 −42,68
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
M - Exercise −500 0 −100,00
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −11 600 2 021 −85,16 50,11 −581 276 101 272
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 11 600 13 621 573,97 39,87 462 492 543 069
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 1 581 −24,03 50,00 −25 000 79 050
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 2 081 31,63 39,87 19 935 82 969
2020-09-23 2020-09-22 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −50 000 650 391 −7,14 50,41 −2 520 460 32 785 690
2020-09-23 2020-09-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 000 1 581 −55,85 50,18 −100 360 79 335
2020-06-26 2020-06-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −9 914 2 021 −83,07 60,11 −595 907 121 477
2020-06-26 2020-06-24 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 11 935 −29,52 58,80 −294 000 701 778
2020-06-19 2020-06-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 16 935 −37,13 58,32 −583 250 987 734
2020-06-19 2020-06-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 000 3 581 −35,84 58,25 −116 500 208 593
2020-06-19 2020-06-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 000 26 935 −35,77 57,90 −868 521 1 559 574
2020-03-27 2020-03-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 5 581 −15,20 47,00 −47 000 262 307
2020-03-27 2020-03-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 000 41 935 −26,35 47,00 −705 000 1 970 945
2020-03-27 2020-03-17 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −4 349 71 935 −5,70 45,00 −195 705 3 237 075
2020-03-27 2020-03-17 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −5 651 76 284 −6,90 45,00 −254 295 3 432 780
2020-03-27 2020-03-17 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −5 421 81 935 −6,21 44,50 −241 234 3 646 108
2020-03-27 2020-03-17 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −4 579 87 356 −4,98 44,50 −203 766 3 887 342
2020-03-23 2020-03-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 6 581 −13,19 45,00 −45 000 296 145
2020-03-23 2020-03-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 56 545 −8,12 46,00 −230 000 2 601 070
2020-03-23 2020-03-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 61 545 −13,98 44,75 −447 546 2 754 422
2020-03-19 2020-03-17 4 IONS IONIS PHARMACEUTICALS INC
COMMON STOCK
S - Sale X −4 349 71 545 −5,73 45,00 −195 705 3 219 525
2020-03-19 2020-03-17 4 IONS IONIS PHARMACEUTICALS INC
COMMON STOCK
S - Sale X −5 651 75 894 −6,93 45,00 −254 295 3 415 230
2020-03-19 2020-03-17 4 IONS IONIS PHARMACEUTICALS INC
COMMON STOCK
S - Sale X −5 421 81 545 −6,23 44,50 −241 234 3 628 752
2020-03-19 2020-03-17 4 IONS IONIS PHARMACEUTICALS INC
COMMON STOCK
S - Sale X −4 969 86 966 −5,40 44,50 −221 120 3 869 987
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −3 317 6 627 −33,36
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −39 643 72 160 −35,46
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 5 545 5 545
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 62 982 62 982
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes −1 268 7 581 −14,33 62,06 −78 692 470 477
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3 317 8 849 59,96
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes −17 342 91 935 −15,87 62,06 −1 076 245 5 705 486
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 39 643 109 277 56,93
2020-01-03 2020-01-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 12 477 12 477
2020-01-03 2020-01-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 141 709 141 709
2020-01-03 2019-12-06 5 IONS IONIS PHARMACEUTICALS INC
Common Stock
G - Gift −25 000 700 391 −3,45
2019-08-22 2019-08-21 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 27 180 −26,90
2019-08-22 2019-08-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 69 634 −12,56 72,15 −721 500 5 024 093
2019-08-22 2019-08-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 79 634 14,36 39,87 398 700 3 175 008
2019-08-22 2019-08-20 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −2 000 500 −80,00
2019-08-22 2019-08-20 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 37 180 −21,20
2019-08-22 2019-08-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 000 5 532 −26,55 71,00 −142 000 392 772
2019-08-22 2019-08-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2 000 7 532 36,15 39,87 79 740 300 301
2019-08-22 2019-08-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 69 634 −12,56 71,00 −710 000 4 944 014
2019-08-22 2019-08-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 79 634 14,36 39,87 398 700 3 175 008
2019-07-22 2019-07-18 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 47 180 −17,49
2019-07-22 2019-07-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 69 634 −12,56 70,25 −702 506 4 891 830
2019-07-22 2019-07-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 79 634 14,36 39,87 398 700 3 175 008
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −700 2 500 −21,88
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −300 0 −100,00
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −13 320 57 180 −18,89
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −6 680 0 −100,00
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −700 5 532 −11,23 84,75 −59 325 468 837
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 700 6 232 12,65 39,87 27 909 248 470
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −300 5 532 −5,14 84,75 −25 425 468 837
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 300 5 832 5,42 10,82 3 246 63 102
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −13 320 69 634 −16,06 84,56 −1 126 370 5 888 411
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 13 320 82 954 19,13 39,87 531 068 3 307 376
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −6 680 69 634 −8,75 84,75 −566 130 5 901 482
2019-04-17 2019-04-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6 680 76 314 9,59 14,69 98 129 1 121 053
2019-04-17 2019-04-15 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 300 −76,92
2019-04-17 2019-04-15 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 6 680 −59,95
2019-04-17 2019-04-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 5 532 −15,31 85,25 −85 250 471 603
2019-04-17 2019-04-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 6 532 18,08 10,82 10 820 70 676
2019-04-17 2019-04-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 69 634 −12,56 85,25 −852 500 5 936 298
2019-04-17 2019-04-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 79 634 14,36 14,69 146 900 1 169 823
2019-02-27 2019-02-26 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −37 000 70 500 −34,42
2019-02-27 2019-02-26 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −37 000 69 634 −34,70 61,54 −2 276 799 4 284 935
2019-02-27 2019-02-26 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 37 000 106 634 53,13 39,87 1 475 190 4 251 498
2019-02-27 2019-02-25 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −40 000 107 500 −27,12
2019-02-27 2019-02-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −40 000 69 634 −36,49 60,07 −2 402 700 4 182 740
2019-02-27 2019-02-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 40 000 109 634 57,44 39,87 1 594 800 4 371 108
2019-02-14 2019-02-13 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −5 300 3 200 −62,35
2019-02-14 2019-02-13 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 604 1 300 −55,23
2019-02-14 2019-02-13 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −40 000 147 500 −21,33
2019-02-14 2019-02-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 300 5 532 −48,93 60,00 −318 000 331 920
2019-02-14 2019-02-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 300 10 832 95,81 39,87 211 311 431 872
2019-02-14 2019-02-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 604 5 532 −22,48 60,00 −96 240 331 920
2019-02-14 2019-02-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 604 7 136 28,99 10,82 17 355 77 212
2019-02-14 2019-02-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −40 000 69 634 −36,49 60,10 −2 404 028 4 185 052
2019-02-14 2019-02-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 40 000 109 634 57,44 39,87 1 594 800 4 371 108
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −2 346 4 612 −33,72
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −30 587 48 077 −38,88
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 5 332 5 332
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 63 726 63 726
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes −942 5 532 −14,55 58,26 −54 881 322 294
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2 346 6 474 56,83
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes −12 686 69 634 −15,41 58,26 −739 086 4 056 877
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 30 587 82 320 59,12
2019-01-03 2019-01-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 12 000 12 000
2019-01-03 2019-01-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 143 400 143 400
2018-04-19 2018-04-17 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −4 000 2 904 −57,94
2018-04-19 2018-04-17 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −9 962 16 680 −37,39
2018-04-19 2018-04-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 000 4 128 −32,64 44,50 −89 000 183 696
2018-04-19 2018-04-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2 000 6 128 48,45 10,82 21 640 66 305
2018-04-19 2018-04-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2 000 6 128 48,45 10,82 21 640 66 305
2018-04-19 2018-04-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 000 4 128 −32,64 44,30 −88 600 182 870
2018-04-19 2018-04-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −4 981 51 733 −8,78 44,50 −221 654 2 302 118
2018-04-19 2018-04-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4 981 56 714 9,63 14,69 73 171 833 129
2018-04-19 2018-04-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4 981 56 714 9,63 14,69 73 171 833 129
2018-04-19 2018-04-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −4 981 51 733 −8,78 44,30 −220 658 2 291 772
2018-01-31 2018-01-29 4/A IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 6 904 −12,65
2018-01-31 2018-01-29 4/A IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 26 642 −27,29
2018-01-31 2018-01-29 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 4 128 −19,50 54,12 −54 120 223 407
2018-01-31 2018-01-29 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 5 128 24,22 10,82 10 820 55 485
2018-01-31 2018-01-29 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 51 733 −16,20 54,12 −541 200 2 799 790
2018-01-31 2018-01-29 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 61 733 19,33 14,69 146 900 906 858
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −1 722 3 047 −36,11
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −29 612 43 515 −40,49
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 3 911 3 911
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 35 149 35 149
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −656 4 128 −13,71 51,76 −33 955 213 665
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1 722 4 784 56,24
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −15 893 51 733 −23,50 51,76 −822 622 2 677 700
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 29 612 67 626 77,90
2018-01-10 2018-01-08 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 7 904 −11,23
2018-01-10 2018-01-08 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 36 642 −21,44
2018-01-10 2018-01-08 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 3 062 −24,62 52,01 −52 010 159 255
2018-01-10 2018-01-08 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 4 062 32,66 10,82 10 820 43 951
2018-01-10 2018-01-08 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 38 014 −20,83 52,01 −520 100 1 977 108
2018-01-10 2018-01-08 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 48 014 26,31 14,69 146 900 705 326
2018-01-05 2018-01-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 096 8 904 −10,96
2018-01-05 2018-01-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −904 0 −100,00
2018-01-05 2018-01-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −20 000 46 642 −30,01
2018-01-05 2018-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 096 3 062 −26,36 50,02 −54 822 153 161
2018-01-05 2018-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 096 4 158 35,79 10,82 11 859 44 990
2018-01-05 2018-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −904 3 062 −22,79 49,71 −44 938 152 212
2018-01-05 2018-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 904 3 966 29,52 7,25 6 554 28 754
2018-01-05 2018-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −20 000 38 014 −34,47 50,02 −1 000 400 1 901 460
2018-01-05 2018-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20 000 58 014 52,61 14,69 293 800 852 226
2018-01-02 2018-01-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 17 603 17 603
2018-01-02 2018-01-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 158 175 158 175
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 500 904 −62,40
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −15 000 66 642 −18,37
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 500 3 062 −32,88 59,46 −89 190 182 067
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 500 4 562 48,99 7,25 10 875 33 074
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 000 38 014 −28,29 59,46 −891 900 2 260 312
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 15 000 53 014 39,46 14,69 220 350 778 776
2017-10-04 2017-10-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 2 404 −29,38
2017-10-04 2017-10-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 81 642 −10,91
2017-10-04 2017-10-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 3 062 −14,04 54,25 −27 125 166 114
2017-10-04 2017-10-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 3 562 16,33 7,25 3 625 25 824
2017-10-04 2017-10-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 3 562 16,33 7,25 3 625 25 824
2017-10-04 2017-10-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 3 062 −14,04 54,20 −27 100 165 960
2017-10-04 2017-10-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 38 014 −11,62 54,25 −271 250 2 062 260
2017-10-04 2017-10-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 43 014 13,15 14,69 73 450 631 876
2017-10-04 2017-10-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 43 014 13,15 14,69 73 450 631 876
2017-10-04 2017-10-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 38 014 −11,62 54,20 −271 000 2 060 359
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 500 3 404 −30,59
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −15 000 91 642 −14,07
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 3 062 −14,04 52,50 −26 250 160 755
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 3 562 16,33 7,25 3 625 25 824
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 3 562 16,33 7,25 3 625 25 824
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 3 562 16,33 7,25 3 625 25 824
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 3 062 −14,04 52,05 −26 025 159 377
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 3 062 −14,04 51,45 −25 725 157 540
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 38 014 −11,62 52,50 −262 500 1 995 735
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 43 014 13,15 14,69 73 450 631 876
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 43 014 13,15 14,69 73 450 631 876
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 43 014 13,15 14,69 73 450 631 876
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 38 014 −11,62 52,05 −260 250 1 978 629
2017-10-04 2017-10-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 38 014 −11,62 51,45 −257 250 1 955 820
2017-07-24 2017-07-20 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option
M - Exercise −1 000 4 904 −16,94
2017-07-24 2017-07-20 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 106 642 −8,57
2017-07-24 2017-07-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 3 062 −24,62 55,35 −55 350 169 482
2017-07-24 2017-07-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 4 062 32,66 7,25 7 250 29 450
2017-07-24 2017-07-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 38 014 −20,83 55,35 −553 500 2 104 075
2017-07-24 2017-07-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 48 014 26,31 14,69 146 900 705 326
2017-07-18 2017-07-17 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 500 5 904 −20,26
2017-07-18 2017-07-17 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −15 000 116 642 −11,39
2017-07-18 2017-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 500 3 062 −32,88 52,45 −78 675 160 602
2017-07-18 2017-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 500 4 562 48,99 7,25 10 875 33 074
2017-07-18 2017-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 000 38 014 −28,29 52,45 −786 750 1 993 834
2017-07-18 2017-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 15 000 53 014 39,46 14,69 220 350 778 776
2017-07-13 3 AKCA AKCEA THERAPEUTICS, INC.
No securities are beneficially owned.
0
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 500 7 404 −16,85
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 538 131 642 −1,15
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −13 462 0 −100,00
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 500 3 062 −32,88 52,10 −78 150 159 530
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 500 4 562 48,99 7,25 10 875 33 074
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 538 38 014 −3,89 52,30 −80 437 1 988 132
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 538 39 552 4,05 14,69 22 593 581 019
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −13 462 38 014 −26,15 52,08 −701 101 1 979 769
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 13 462 51 476 35,41 7,25 97 600 373 201
2017-04-27 2017-04-25 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 500 8 904 −14,42
2017-04-27 2017-04-25 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −15 000 13 462 −52,70
2017-04-27 2017-04-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 500 3 062 −32,88 47,81 −71 715 146 394
2017-04-27 2017-04-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 500 4 562 48,99 7,25 10 875 33 074
2017-04-27 2017-04-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 000 38 014 −28,29 47,81 −717 150 1 817 449
2017-04-27 2017-04-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 15 000 53 014 39,46 7,25 108 750 384 352
2017-04-21 2017-04-19 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −500 10 404 −4,59
2017-04-21 2017-04-19 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −5 000 28 462 −14,94
2017-04-21 2017-04-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 3 062 −14,04 43,25 −21 625 132 432
2017-04-21 2017-04-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 3 562 16,33 7,25 3 625 25 824
2017-04-21 2017-04-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 38 014 −11,62 43,25 −216 250 1 644 106
2017-04-21 2017-04-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 43 014 13,15 7,25 36 250 311 852
2017-04-13 2017-04-13 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −500 10 904 −4,38
2017-04-13 2017-04-13 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −500 10 904 −4,38
2017-04-13 2017-04-13 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 33 462 −23,01
2017-04-13 2017-04-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 3 062 −14,04 41,30 −20 650 126 461
2017-04-13 2017-04-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 3 062 −14,04 41,30 −20 650 126 461
2017-04-13 2017-04-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 3 562 16,33 7,25 3 625 25 824
2017-04-13 2017-04-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 3 562 16,33 10,29 5 145 36 653
2017-04-13 2017-04-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 38 014 −20,83 41,30 −413 000 1 569 978
2017-04-13 2017-04-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 48 014 26,31 7,25 72 500 348 102
2017-04-13 2017-04-12 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 500 −66,67
2017-04-13 2017-04-12 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 43 462 −18,70
2017-04-13 2017-04-12 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 3 062 −24,62 40,07 −40 070 122 694
2017-04-13 2017-04-12 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 4 062 32,66 10,29 10 290 41 798
2017-04-13 2017-04-12 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 38 014 −20,83 40,07 −400 700 1 523 221
2017-04-13 2017-04-12 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 48 014 26,31 7,25 72 500 348 102
2017-03-06 2017-03-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 100 1 500 −42,31
2017-03-06 2017-03-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −11 000 53 462 −17,06
2017-03-06 2017-03-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 100 3 062 −26,43 51,05 −56 155 156 315
2017-03-06 2017-03-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 100 4 162 35,92 10,29 11 319 42 827
2017-03-06 2017-03-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −11 000 38 014 −22,44 51,05 −561 550 1 940 615
2017-03-06 2017-03-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 11 000 49 014 28,94 7,25 79 750 355 352
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −131 3 062 −4,10 46,29 −6 064 141 740
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −142 2 859 −4,73 46,29 −6 573 132 346
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −139 2 638 −5,01 46,29 −6 434 122 113
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −163 2 423 −6,30 46,29 −7 545 112 163
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −4 410 38 014 −10,40 46,29 −204 139 1 759 668
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −3 728 34 291 −9,81 46,29 −172 569 1 587 330
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −4 236 31 144 −11,97 46,29 −196 080 1 441 625
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −3 008 27 568 −9,84 46,29 −139 237 1 276 095
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −334 999 −25,06
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −363 724 −33,39
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −354 354 −50,00
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −416 0 −100,00
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −8 133 24 397 −25,00
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −6 875 13 750 −33,33
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −7 812 7 812 −50,00
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −5 547 0 −100,00
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2 692 2 692
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 27 168 27 168
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 334 3 193 11,68
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 363 3 001 13,76
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 354 2 777 14,61
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 416 2 586 19,17
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 8 133 42 424 23,72
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 6 875 38 019 22,07
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 7 812 35 380 28,34
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5 547 30 576 22,16
2017-01-12 2017-01-10 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 200 2 600 −31,58
2017-01-12 2017-01-10 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −12 000 64 462 −15,69
2017-01-12 2017-01-10 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 200 2 170 −35,61 49,25 −59 100 106 872
2017-01-12 2017-01-10 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 200 3 370 55,30 10,29 12 348 34 677
2017-01-12 2017-01-10 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −12 000 25 029 −32,41 49,25 −591 000 1 232 678
2017-01-12 2017-01-10 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 12 000 37 029 47,94 7,25 87 000 268 460
2017-01-04 2017-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −700 3 800 −15,56
2017-01-04 2017-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −7 000 76 462 −8,39
2017-01-04 2017-01-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −700 2 170 −24,39 50,10 −35 070 108 717
2017-01-04 2017-01-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 700 2 870 32,26 10,29 7 203 29 532
2017-01-04 2017-01-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −7 000 25 029 −21,86 50,10 −350 700 1 253 953
2017-01-04 2017-01-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7 000 32 029 27,97 7,25 50 750 232 210
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 4 500 −18,18
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 83 462 −10,70
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 16 157 16 157
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 163 013 163 013
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 2 170 −18,73 48,80 −24 400 105 896
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 2 670 23,04 10,29 5 145 27 474
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 2 670 23,04 10,29 5 145 27 474
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 2 170 −18,73 47,30 −23 650 102 641
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 25 029 −16,65 48,80 −244 000 1 221 415
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 30 029 19,98 7,25 36 250 217 710
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 30 029 19,98 7,25 36 250 217 710
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 25 029 −16,65 47,30 −236 500 1 183 872
2016-11-14 2016-11-10 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 5 500 −15,38
2016-11-14 2016-11-10 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 93 462 −9,67
2016-11-14 2016-11-10 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 2 170 −31,55 42,22 −42 220 91 617
2016-11-14 2016-11-10 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 3 170 46,08 10,29 10 290 32 619
2016-11-14 2016-11-10 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 25 029 −28,55 40,23 −402 300 1 006 917
2016-11-14 2016-11-10 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 35 029 39,95 7,25 72 500 253 960
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −2 000 6 500 −23,53
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −3 741 103 462 −3,49
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −16 259 0 −100,00
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 2 170 −31,55 37,25 −37 250 80 832
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 3 170 46,08 10,29 10 290 32 619
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 3 170 46,08 10,29 10 290 32 619
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 2 170 −31,55 35,10 −35 100 76 167
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −3 741 25 029 −13,00 37,50 −140 288 938 588
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3 741 28 770 14,95 7,25 27 122 208 582
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −6 259 25 029 −20,00 37,10 −232 209 928 576
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6 259 31 288 25,01 10,29 64 405 321 954
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 25 029 −28,55 35,55 −355 500 889 781
2016-11-14 2016-11-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 35 029 39,95 10,29 102 900 360 448
2016-10-07 2016-10-05 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 8 500 −10,53
2016-10-07 2016-10-05 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 16 259 −38,08
2016-10-07 2016-10-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 2 170 −31,55 36,61 −36 610 79 444
2016-10-07 2016-10-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 3 170 46,08 10,29 10 290 32 619
2016-10-07 2016-10-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 25 029 −28,55 36,61 −366 100 916 312
2016-10-07 2016-10-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 35 029 39,95 10,29 102 900 360 448
2016-09-29 2016-09-27 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −2 000 9 500 −17,39
2016-09-29 2016-09-27 4 IONS IONIS PHARMACEUTICALS INC
Empoyee Stock Option (right to buy)
M - Exercise −20 000 26 259 −43,23
2016-09-29 2016-09-27 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 000 2 170 −47,96 36,05 −72 100 78 228
2016-09-29 2016-09-27 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2 000 4 170 92,17 10,29 20 580 42 909
2016-09-29 2016-09-27 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −20 000 25 029 −44,42 36,02 −720 400 901 545
2016-09-29 2016-09-27 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20 000 45 029 79,91 10,29 205 800 463 348
2016-09-23 2016-09-21 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −2 000 11 500 −14,81
2016-09-23 2016-09-21 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −20 000 46 259 −30,18
2016-09-23 2016-09-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 000 2 170 −47,96 35,50 −71 000 77 035
2016-09-23 2016-09-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2 000 4 170 92,17 10,29 20 580 42 909
2016-09-23 2016-09-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −20 000 25 029 −44,42 35,50 −710 000 888 530
2016-09-23 2016-09-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20 000 45 029 79,91 10,29 205 800 463 348
2016-04-07 2016-04-06 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 13 500 −6,90
2016-04-07 2016-04-06 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 66 259 −13,11
2016-04-07 2016-04-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 2 170 −18,73 46,30 −23 150 100 471
2016-04-07 2016-04-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 2 670 23,04 10,29 5 145 27 474
2016-04-07 2016-04-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 2 670 23,04 10,29 5 145 27 474
2016-04-07 2016-04-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 2 170 −18,73 45,95 −22 975 99 712
2016-04-07 2016-04-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 25 029 −16,65 46,30 −231 500 1 158 843
2016-04-07 2016-04-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 30 029 19,98 10,29 51 450 308 998
2016-04-07 2016-04-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 30 029 19,98 10,29 51 450 308 998
2016-04-07 2016-04-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 25 029 −16,65 45,95 −229 750 1 150 083
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −500 14 500 −3,33
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −500 14 500 −3,33
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 76 259 −11,59
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 2 170 −18,73 40,75 −20 375 88 428
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 2 670 23,04 10,29 5 145 27 474
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 2 170 −18,73 40,72 −20 360 88 362
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 2 670 23,04 9,22 4 610 24 617
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 25 029 −16,65 40,72 −203 600 1 019 181
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 30 029 19,98 10,29 51 450 308 998
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 30 029 19,98 10,29 51 450 308 998
2016-04-01 2016-03-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 25 029 −16,65 40,75 −203 750 1 019 932
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −145 2 170 −6,26 41,46 −6 012 89 968
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −141 1 952 −6,74 41,46 −5 846 80 936
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −166 1 739 −8,71 41,46 −6 883 72 103
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −124 1 489 −7,69 41,46 −5 141 61 735
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −3 798 25 029 −13,18 41,47 −157 486 1 037 840
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −4 317 21 952 −16,43 41,46 −178 962 910 022
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −3 065 18 456 −14,24 41,46 −127 069 765 153
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale −1 645 15 974 −9,34 41,46 −68 199 662 253
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −363 1 087 −25,03
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −354 708 −33,33
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −416 416 −50,00
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −316 0 −100,00
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −6 875 20 625 −25,00
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −7 813 15 624 −33,34
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −5 547 5 547 −50,00
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −2 977 0 −100,00
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1 333 1 333
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 32 530 32 530
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 363 2 315 18,60
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 354 2 093 20,36
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 416 1 905 27,94
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 316 1 613 24,36
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 6 875 28 827 31,32
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 7 813 26 269 42,33
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5 547 21 521 34,73
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2 977 17 619 20,33
2016-01-07 2016-01-05 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −500 500 −50,00
2016-01-07 2016-01-05 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −5 000 86 259 −5,48
2016-01-07 2016-01-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 1 297 −27,82 62,10 −31 050 80 544
2016-01-07 2016-01-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 1 797 38,55 9,22 4 610 16 568
2016-01-07 2016-01-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 14 642 −25,46 62,10 −310 500 909 268
2016-01-07 2016-01-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 19 642 34,15 10,29 51 450 202 116
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 1 000 −50,00
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 91 259 −9,88
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 8 000 8 000
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 195 182 195 182
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 1 297 −43,54 61,05 −61 050 79 182
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 2 297 77,10 9,22 9 220 21 178
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 14 642 −40,58 61,05 −610 500 893 894
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 24 642 68,30 10,29 102 900 253 566
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −2 500 2 000 −55,56
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −20 837 101 259 −17,07
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −4 163 0 −100,00
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 1 297 −27,82 45,30 −22 650 58 754
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 1 797 38,55 9,22 4 610 16 568
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 000 1 297 −60,66 44,18 −88 350 57 295
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2 000 3 297 154,20 9,22 18 440 30 398
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 14 642 −25,46 45,30 −226 500 663 283
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 19 642 34,15 10,29 51 450 202 116
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 837 14 642 −51,96 44,18 −699 599 646 810
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 15 837 30 479 108,16 10,29 162 963 313 629
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −4 163 14 642 −22,14 43,90 −182 756 642 784
2015-10-23 2015-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4 163 18 805 28,43 11,27 46 917 211 932
2015-10-23 2015-10-21 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −500 4 500 −10,00
2015-10-23 2015-10-21 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 0 −100,00
2015-10-23 2015-10-21 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −15 000 4 163 −78,28
2015-10-23 2015-10-21 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −500 1 297 −27,82 43,00 −21 500 55 771
2015-10-23 2015-10-21 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 500 1 797 38,55 9,22 4 610 16 568
2015-10-23 2015-10-21 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 1 297 −43,54 43,00 −43 000 55 771
2015-10-23 2015-10-21 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 2 297 77,10 11,27 11 270 25 887
2015-10-23 2015-10-21 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 000 14 642 −50,60 43,00 −645 000 629 606
2015-10-23 2015-10-21 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 15 000 29 642 102,45 11,27 169 050 334 065
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 175 5 000 −19,03
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −5 000 19 163 −20,69
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 175 1 297 −47,53 57,01 −66 983 73 938
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 175 2 472 90,59 9,22 10 834 22 792
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 14 642 −25,46 57,01 −285 035 834 696
2015-07-08 2015-07-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 19 642 34,15 11,27 56 350 221 365
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 175 6 175 −15,99
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −5 000 24 163 −17,15
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 175 1 297 −47,53 57,56 −67 634 74 657
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 175 2 472 90,59 9,22 10 834 22 792
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 14 642 −25,46 57,56 −287 805 842 808
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 19 642 34,15 11,27 56 350 221 365
2015-04-08 2015-04-07 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −2 034 7 350 −21,68
2015-04-08 2015-04-07 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −20 343 29 163 −41,09
2015-04-08 2015-04-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 034 1 297 −61,06 63,07 −128 286 81 803
2015-04-08 2015-04-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2 034 3 331 156,82 9,22 18 753 30 712
2015-04-08 2015-04-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −20 343 14 642 −58,15 63,07 −1 283 053 923 486
2015-04-08 2015-04-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20 343 34 985 138,94 11,27 229 266 394 281
2015-04-06 2015-04-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 966 9 384 −17,32
2015-04-06 2015-04-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −19 657 49 506 −28,42
2015-04-06 2015-04-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 966 1 297 −60,25 61,93 −121 759 80 326
2015-04-06 2015-04-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 966 3 263 151,58 9,22 18 127 30 085
2015-04-06 2015-04-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −19 657 14 642 −57,31 61,93 −1 217 399 906 810
2015-04-06 2015-04-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 19 657 34 299 134,25 11,27 221 534 386 550
2015-01-29 2015-01-27 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 11 350 −8,10
2015-01-29 2015-01-27 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 69 163 −12,63
2015-01-29 2015-01-27 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 1 297 −43,54 72,93 −72 926 94 585
2015-01-29 2015-01-27 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 2 297 77,10 9,22 9 220 21 178
2015-01-29 2015-01-27 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 14 642 −40,58 72,93 −729 260 1 067 782
2015-01-29 2015-01-27 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 24 642 68,30 11,27 112 700 277 715
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −136 1 297 −9,49 67,96 −9 243 88 149
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −160 1 079 −12,91 67,96 −10 874 73 333
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −121 822 −12,83 67,96 −8 224 55 866
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −4 130 14 642 −22,00 67,96 −280 693 995 136
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −2 933 10 959 −21,11 67,96 −199 338 744 817
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −1 574 8 344 −15,87 67,96 −106 975 567 092
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −354 1 062 −25,00
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −417 832 −33,39
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −316 316 −50,00
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −7 813 23 437 −25,00
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −5 548 11 094 −33,34
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −2 977 2 977 −50,00
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1 450 1 450
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 27 500 27 500
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 354 1 433 32,81
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 417 1 239 50,73
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 316 943 50,40
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 7 813 18 772 71,29
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5 548 13 892 66,49
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2 977 9 918 42,89
2015-01-13 2015-01-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 12 350 −7,49
2015-01-13 2015-01-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 79 163 −11,22
2015-01-13 2015-01-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 627 −61,46 73,57 −73 570 46 128
2015-01-13 2015-01-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 1 627 159,49 9,22 9 220 15 001
2015-01-13 2015-01-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 6 941 −59,03 73,57 −735 700 510 649
2015-01-13 2015-01-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 16 941 144,07 11,27 112 700 190 925
2015-01-08 2015-01-07 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 13 350 −6,97
2015-01-08 2015-01-07 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 89 163 −10,08
2015-01-08 2015-01-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 627 −61,46 68,05 −68 048 42 666
2015-01-08 2015-01-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 1 627 159,49 9,22 9 220 15 001
2015-01-08 2015-01-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 6 941 −59,03 68,05 −680 480 472 321
2015-01-08 2015-01-07 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 16 941 144,07 11,27 112 700 190 925
2015-01-08 2015-01-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 14 350 −6,51
2015-01-08 2015-01-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 99 163 −9,16
2015-01-08 2015-01-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 627 −61,46 66,04 −66 038 41 406
2015-01-08 2015-01-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 1 627 159,49 9,22 9 220 15 001
2015-01-08 2015-01-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 6 941 −59,03 66,04 −660 380 458 370
2015-01-08 2015-01-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 16 941 144,07 11,27 112 700 190 925
2015-01-05 2015-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 8 700 8 700
2015-01-05 2015-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 165 000 165 000
2014-10-24 2014-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 600 15 350 −9,44
2014-10-24 2014-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 109 163 −8,39
2014-10-24 2014-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −3 000 0 −100,00
2014-10-24 2014-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 600 627 −71,85 42,22 −67 552 26 472
2014-10-24 2014-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 600 2 227 255,18 9,22 14 752 20 533
2014-10-24 2014-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 6 941 −59,03 42,22 −422 200 293 049
2014-10-24 2014-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 16 941 144,07 11,27 112 700 190 925
2014-10-24 2014-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −3 000 6 941 −30,18 42,22 −126 660 293 049
2014-10-24 2014-10-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3 000 9 941 43,22 14,47 43 410 143 846
2014-10-03 2014-10-03 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 16 950 −5,57
2014-10-03 2014-10-03 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −13 000 3 000 −81,25
2014-10-03 2014-10-03 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 627 −61,46 39,49 −39 487 24 758
2014-10-03 2014-10-03 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 1 627 159,49 9,22 9 220 15 001
2014-10-03 2014-10-03 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −13 000 6 941 −65,19 39,49 −513 331 274 079
2014-10-03 2014-10-03 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 13 000 19 941 187,29 14,47 188 110 288 546
2014-10-03 2014-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −800 17 950 −4,27
2014-10-03 2014-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 200 1 000 −54,55
2014-10-03 2014-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −20 000 16 000 −55,56
2014-10-03 2014-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −800 627 −56,06 37,91 −30 329 23 770
2014-10-03 2014-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 800 1 427 127,59 9,22 7 376 13 157
2014-10-03 2014-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 200 627 −65,68 37,91 −45 493 23 770
2014-10-03 2014-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 200 1 827 191,39 11,27 13 524 20 590
2014-10-03 2014-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −20 000 6 941 −74,24 37,91 −758 220 263 140
2014-10-03 2014-10-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20 000 26 941 288,14 14,47 289 400 389 836
2014-08-15 2014-08-13 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 600 2 200 −42,11
2014-08-15 2014-08-13 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −15 500 36 000 −30,10
2014-08-15 2014-08-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 600 627 −71,85 35,45 −56 726 22 230
2014-08-15 2014-08-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 600 2 227 255,18 11,27 18 032 25 098
2014-08-15 2014-08-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 500 6 941 −69,07 35,45 −549 537 246 086
2014-08-15 2014-08-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 15 500 22 441 223,31 14,47 224 285 324 721
2014-08-01 2014-08-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 3 800 −20,83
2014-08-01 2014-08-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −15 000 51 500 −22,56
2014-08-01 2014-08-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 627 −61,46 30,52 −30 525 19 139
2014-08-01 2014-08-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 1 627 159,49 11,27 11 270 18 336
2014-08-01 2014-08-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 000 6 941 −68,37 30,52 −457 875 211 874
2014-08-01 2014-08-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 15 000 21 941 216,11 14,47 217 050 317 486
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 800 4 800 −27,27
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −200 0 −100,00
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 15 500 66 500 30,39
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 800 627 −74,17 35,55 −63 990 22 290
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 800 2 427 287,08 11,27 20 286 27 352
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −200 627 −24,18 35,55 −7 110 22 290
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 200 827 31,90 14,47 2 894 11 967
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 500 6 941 −69,07 35,58 −551 459 246 947
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 15 500 22 441 223,31 14,47 224 285 324 721
2014-06-20 2014-06-19 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −11 000 82 000 −11,83
2014-06-20 2014-06-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −11 000 6 941 −61,31 35,10 −386 111 243 636
2014-06-20 2014-06-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 11 000 17 941 158,48 14,47 159 170 259 606
2014-06-12 2014-06-10 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 000 200 −83,33
2014-06-12 2014-06-10 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 93 000 −9,71
2014-06-12 2014-06-10 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 000 627 −61,46 33,46 −33 455 20 976
2014-06-12 2014-06-10 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 000 1 627 159,49 14,47 14 470 23 543
2014-06-12 2014-06-10 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 6 941 −59,03 33,46 −334 550 232 211
2014-06-12 2014-06-10 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 16 941 144,07 14,47 144 700 245 136
2014-04-04 2014-04-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 800 1 200 −60,00
2014-04-04 2014-04-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −7 000 103 000 −6,36
2014-04-04 2014-04-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 800 627 −74,17 43,65 −78 566 27 367
2014-04-04 2014-04-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 800 2 427 287,08 14,47 26 046 35 119
2014-04-04 2014-04-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −7 000 6 941 −50,21 43,65 −305 536 302 961
2014-04-04 2014-04-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7 000 13 941 100,85 14,47 101 290 201 726
2014-01-17 2014-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −121 627 −16,18 47,08 −5 697 29 520
2014-01-17 2014-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −160 431 −27,07 47,08 −7 533 20 291
2014-01-17 2014-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −1 134 6 941 −14,04 47,08 −53 390 326 790
2014-01-17 2014-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −2 112 5 097 −29,30 47,08 −99 435 239 973
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted StockUnits
M - Exercise −317 632 −33,40
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −417 1 249 −25,03
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −2 978 5 954 −33,34
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −5 548 16 642 −25,00
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1 416 1 416
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 31 250 31 250
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 317 748 73,55
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 417 591 239,66
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2 978 8 075 58,43
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5 548 7 209 334,02
2014-01-10 2014-01-08 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 500 3 000 −33,33
2014-01-10 2014-01-08 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −11 000 110 000 −9,09
2014-01-10 2014-01-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 500 174 −89,61 40,05 −60 078 6 969
2014-01-10 2014-01-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 500 1 674 862,07 14,47 21 705 24 223
2014-01-10 2014-01-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −11 000 1 661 −86,88 40,05 −440 572 66 526
2014-01-10 2014-01-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 11 000 12 661 662,25 14,47 159 170 183 205
2014-01-03 2014-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 8 500 8 500
2014-01-03 2014-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 187 500 187 500
2014-01-03 2014-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 500 174 −93,49 39,25 −98 132 6 830
2014-01-03 2014-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2 500 2 674 1 436,78 14,47 36 175 38 693
2014-01-03 2014-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −4 000 1 661 −70,66 40,00 −160 000 66 440
2014-01-03 2014-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4 000 5 661 240,82 14,47 57 880 81 915
2014-01-03 2014-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −25 000 1 661 −93,77 39,25 −981 325 65 199
2014-01-03 2014-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 25 000 26 661 1 505,12 14,47 361 750 385 785
2013-09-23 2013-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −8 740 0 −100,00
2013-09-23 2013-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −8 740 1 661 −84,03 35,90 −313 749 59 627
2013-09-23 2013-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8 740 10 401 526,19 11,12 97 189 115 659
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −50 000 8 740 −85,12
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −30 000 1 661 −94,75 35,02 −1 050 600 58 168
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30 000 31 661 1 806,14 11,12 333 600 352 070
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −20 000 1 661 −92,33 35,12 −702 480 58 341
2013-09-23 2013-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20 000 21 661 1 204,09 11,12 222 400 240 870
2013-09-11 2013-09-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −20 000 725 391 −2,68 31,18 −623 620 22 618 417
2013-09-11 2013-09-10 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −30 000 745 391 −3,87 31,65 −949 440 23 590 134
2013-09-11 2013-09-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −26 615 58 740 −31,18
2013-09-11 2013-09-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −26 615 1 661 −94,13 30,42 −809 495 50 519
2013-09-11 2013-09-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 26 615 28 276 1 602,35 11,12 295 959 314 429
2013-07-25 2013-07-23 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −11 500 85 355 −11,87
2013-07-25 2013-07-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −11 500 1 661 −87,38 30,00 −345 000 49 830
2013-07-25 2013-07-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 11 500 13 161 692,35 11,12 127 880 146 350
2013-07-22 2013-07-22 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 885 96 855 −1,91
2013-07-22 2013-07-22 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −18 115 0 −100,00
2013-07-22 2013-07-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 885 1 661 −53,16 31,02 −58 473 51 524
2013-07-22 2013-07-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 885 3 546 113,49 11,12 20 961 39 432
2013-07-22 2013-07-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −8 115 1 661 −83,01 31,02 −251 727 51 524
2013-07-22 2013-07-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8 115 9 776 488,56 15,38 124 809 150 355
2013-07-22 2013-07-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 30,52 −305 250 50 702
2013-07-22 2013-07-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 15,38 153 800 179 346
2013-07-22 2013-07-19 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −22 200 18 115 −55,07
2013-07-22 2013-07-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 30,18 −301 850 50 137
2013-07-22 2013-07-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 15,38 153 800 179 346
2013-07-22 2013-07-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 15,38 153 800 179 346
2013-07-22 2013-07-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 30,87 −308 720 51 278
2013-07-22 2013-07-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −2 200 1 661 −56,98 31,40 −69 080 52 155
2013-07-22 2013-07-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2 200 3 861 132,45 15,38 33 836 59 382
2013-07-22 2013-07-18 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −20 000 98 740 −16,84
2013-07-22 2013-07-18 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 30,02 −300 220 49 867
2013-07-22 2013-07-18 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 11,12 111 200 129 670
2013-07-22 2013-07-18 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 11,12 111 200 129 670
2013-07-22 2013-07-18 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 30,20 −302 000 50 162
2013-07-17 2013-07-17 4 ISIS ISIS PHARMACEUTICALS INC
Emloyee Stock Option (right to buy)
M - Exercise −5 000 0 −100,00
2013-07-17 2013-07-17 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −8 300 0 −100,00
2013-07-17 2013-07-17 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 174 −96,64 31,96 −159 800 5 561
2013-07-17 2013-07-17 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 000 5 174 2 873,56 9,92 49 600 51 326
2013-07-17 2013-07-17 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −44 174 −20,18 31,96 −1 406 5 561
2013-07-17 2013-07-17 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 44 218 25,29 15,38 677 3 353
2013-07-17 2013-07-17 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −8 256 174 −97,94 31,22 −257 752 5 432
2013-07-17 2013-07-17 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8 256 8 430 4 744,83 15,38 126 977 129 653
2013-07-17 2013-07-16 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −6 000 118 740 −4,81
2013-07-17 2013-07-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −6 000 1 661 −78,32 33,31 −199 842 55 323
2013-07-17 2013-07-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6 000 7 661 361,23 11,12 66 720 85 190
2013-07-17 2013-07-15 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −30 000 124 740 −19,39
2013-07-17 2013-07-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 33,56 −335 650 55 751
2013-07-17 2013-07-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 11,12 111 200 129 670
2013-07-17 2013-07-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 11,12 111 200 129 670
2013-07-17 2013-07-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 33,80 −338 050 56 150
2013-07-17 2013-07-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 34,05 −340 480 56 554
2013-07-17 2013-07-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 11,12 111 200 129 670
2013-07-12 2013-07-12 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −24 000 36 000 −40,00
2013-07-12 2013-07-12 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −6 000 40 315 −12,95
2013-07-12 2013-07-12 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −12 000 1 661 −87,84 33,50 −402 010 55 645
2013-07-12 2013-07-12 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 12 000 13 661 722,46 11,12 133 440 151 910
2013-07-12 2013-07-12 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 12 000 13 661 722,46 11,12 133 440 151 910
2013-07-12 2013-07-12 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −12 000 1 661 −87,84 33,08 −397 008 54 953
2013-07-12 2013-07-12 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −6 000 1 661 −78,32 32,83 −196 980 54 531
2013-07-12 2013-07-12 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6 000 7 661 361,23 15,38 92 280 117 826
2013-07-12 2013-07-11 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −30 000 46 315 −39,31
2013-07-12 2013-07-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −30 000 1 661 −94,75 32,00 −960 090 53 157
2013-07-12 2013-07-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30 000 311 661 10,65 15,38 461 400 4 793 346
2013-07-12 2013-07-10 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −30 000 76 315 −28,22
2013-07-12 2013-07-10 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −30 000 1 661 −94,75 30,05 −901 440 49 910
2013-07-12 2013-07-10 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30 000 31 661 1 806,14 15,38 461 400 486 946
2013-07-09 2013-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −30 000 106 315 −22,01
2013-07-09 2013-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −30 000 1 661 −94,75 30,04 −901 290 49 901
2013-07-09 2013-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30 000 31 661 1 806,14 15,38 461 400 486 946
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −30 000 136 315 −18,04
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −24 992 1 661 −93,77 30,09 −752 009 49 979
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X 24 992 26 653 1 504,64 15,38 384 377 409 923
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 008 1 661 −75,09 30,03 −150 370 49 873
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 008 6 669 301,51 15,38 77 023 102 569
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −24 180 166 315 −12,69
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −24 180 1 661 −93,57 30,02 −725 763 49 855
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 24 180 25 841 1 455,75 15,38 371 888 397 435
2013-07-01 2013-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 775 391 −1,27 28,17 −281 700 21 842 764
2013-07-01 2013-06-28 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −5 958 0 −100,00
2013-07-01 2013-06-28 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −4 725 0 −100,00
2013-07-01 2013-06-28 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −10 000 0 −100,00
2013-07-01 2013-06-28 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 958 174 −97,16 27,31 −162 713 4 752
2013-07-01 2013-06-28 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5 958 6 132 3 424,14 11,12 66 253 68 188
2013-07-01 2013-06-28 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −4 725 174 −96,45 27,31 −129 040 4 752
2013-07-01 2013-06-28 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4 725 4 899 2 715,52 6,81 32 177 33 362
2013-07-01 2013-06-28 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 27,07 −270 700 44 963
2013-07-01 2013-06-28 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 6,81 68 100 79 411
2013-07-01 2013-06-27 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −20 000 10 000 −66,67
2013-07-01 2013-06-27 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 27,40 −274 000 45 511
2013-07-01 2013-06-27 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 6,81 68 100 79 411
2013-07-01 2013-06-27 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 000 11 661 602,05 6,81 68 100 79 411
2013-07-01 2013-06-27 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 1 661 −85,76 28,30 −283 000 47 006
2013-06-26 2013-06-26 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −20 000 30 000 −40,00
2013-06-26 2013-06-26 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 785 391 −1,26 26,70 −267 000 20 969 940
2013-06-26 2013-06-26 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −20 000 1 661 −92,33 27,10 −542 020 45 015
2013-06-26 2013-06-26 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20 000 21 661 1 204,09 6,81 136 200 147 511
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −30 000 50 000 −37,50
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −19 565 1 661 −92,17 27,86 −545 179 46 284
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 19 565 21 226 1 177,90 6,81 133 238 144 549
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 435 1 661 −86,27 28,32 −295 519 47 040
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10 435 12 096 628,24 6,81 71 062 82 374
2013-06-26 2013-06-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −13 730 795 391 −1,70 25,22 −346 271 20 059 761
2013-06-26 2013-06-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −16 270 809 121 −1,97 25,16 −409 353 20 357 484
2013-04-26 2013-04-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 825 391 −1,20 22,12 −221 200 18 257 649
2013-04-23 2013-04-23 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −30 000 835 391 −3,47 22,10 −662 901 18 459 384
2013-04-23 2013-04-22 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −20 000 0 −100,00
2013-04-23 2013-04-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −10 000 865 391 −1,14 20,99 −209 900 18 164 557
2013-04-23 2013-04-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −20 000 1 661 −92,33 20,99 −419 800 34 864
2013-04-23 2013-04-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20 000 21 661 1 204,09 7,26 145 200 157 259
2013-04-23 2013-04-19 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −30 000 20 000 −60,00
2013-04-23 2013-04-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −30 000 1 661 −94,75 20,01 −600 180 33 230
2013-04-23 2013-04-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30 000 31 661 1 806,14 7,26 217 800 229 859
2013-02-01 2013-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 133 180 133 180
2013-02-01 2013-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 22 190 22 190
2013-01-17 2013-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −143 174 −45,11 14,00 −2 002 2 436
2013-01-17 2013-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale −1 317 1 661 −44,22 14,00 −18 438 23 254
2013-01-17 2013-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1 666 1 666
2013-01-17 2013-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −317 949 −25,04
2013-01-17 2013-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise −2 978 8 932 −25,00
2013-01-17 2013-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 317 317
2013-01-17 2013-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2 978 2 978
2013-01-03 2013-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 10 000 10 000
2012-11-07 2012-11-05 4 RGLS Regulus Therapeutics Inc.
Stock Option (Right to Buy)
A - Award 25 000 25 000
2012-10-11 2012-10-10 4 RGLS Regulus Therapeutics Inc.
Series A Preferred Stock
C - Conversion −6 299 500 0 −100,00
2012-10-11 2012-10-10 4 RGLS Regulus Therapeutics Inc.
Common Stock
P - Purchase 750 000 7 049 500 11,91 4,00 3 000 000 28 198 000
2012-10-11 2012-10-10 4 RGLS Regulus Therapeutics Inc.
Common Stock
C - Conversion 6 299 500 6 299 500
2012-09-21 2012-09-21 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −29 462 0 −100,00
2012-09-21 2012-09-21 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −29 462 0 −100,00 14,06 −414 236
2012-09-21 2012-09-21 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 29 462 29 462 6,84 201 520 201 520
2012-09-21 2012-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −20 538 29 462 −41,08
2012-09-21 2012-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −9 462 0 −100,00
2012-09-21 2012-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X 20 538 0 −100,00 15,01 308 234
2012-09-21 2012-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20 538 20 538 6,84 140 480 140 480
2012-09-21 2012-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −9 462 0 −100,00 15,01 −142 006
2012-09-21 2012-09-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 9 462 9 462 5,25 49 676 49 676
2012-09-21 2012-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −30 000 9 462 −76,02
2012-09-21 2012-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −30 000 0 −100,00 14,82 −444 450
2012-09-21 2012-09-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30 000 30 000 5,25 157 500 157 500
2012-09-17 2012-09-13 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −27 074 39 462 −40,69
2012-09-17 2012-09-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −27 074 0 −100,00 14,55 −393 927
2012-09-17 2012-09-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 27 074 27 074 5,25 142 138 142 138
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −6 000 0 −100,00
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −4 687 0 −100,00
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 925 0 −100,00
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −17 388 66 536 −20,72
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −6 000 0 −100,00 15,00 −90 012
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6 000 6 000 5,25 31 500 31 500
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −306 0 −100,00 15,00 −4 591
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 306 306 5,25 1 606 1 606
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −4 381 0 −100,00 15,04 −65 868
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4 381 4 381 5,25 23 000 23 000
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 925 0 −100,00 15,04 −28 942
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1 925 1 925 6,84 13 167 13 167
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −8 694 0 −100,00 15,04 −130 714
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8 694 8 694 5,25 45 644 45 644
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −8 694 0 −100,00 15,00 −130 427
2012-09-06 2012-09-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8 694 8 694 5,25 45 644 45 644
2012-09-06 2012-09-05 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −15 000 83 924 −15,16
2012-09-06 2012-09-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −15 000 0 −100,00 14,82 −222 345
2012-09-06 2012-09-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 15 000 15 000 5,25 78 750 78 750
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −30 000 98 924 −23,27
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −30 000 0 −100,00 14,11 −423 255
2012-09-06 2012-09-04 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 30 000 30 000 5,25 157 500 157 500
2012-01-17 2012-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1 266 1 266
2012-01-17 2012-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 11 910 11 910
2012-01-03 2012-01-03 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 11 404 11 404
2012-01-03 2012-01-03 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 107 203 107 203
2010-01-05 2010-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 6 600 6 600
2010-01-05 2010-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 119 163 119 163
2004-12-01 2004-12-01 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −5 000 7 051 −41,49
2004-12-01 2004-12-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −5 000 922 241 −0,54 4,90 −24 479 4 515 107
2004-12-01 2004-12-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5 000 927 241 0,54 4,00 20 000 3 708 964
2004-12-01 2004-11-30 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −4 000 12 051 −24,92
2004-12-01 2004-11-30 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −4 000 922 241 −0,43 4,70 −18 820 4 339 144
2004-12-01 2004-11-30 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4 000 926 241 0,43 4,00 16 000 3 704 964
2004-12-01 2004-11-29 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise −1 549 16 051 −8,80
2004-12-01 2004-11-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X −1 549 922 241 −0,17 4,62 −7 153 4 258 817
2004-12-01 2004-11-29 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1 549 923 790 0,17 4,00 6 196 3 695 160
P
Köp på öppna marknaden eller privat köp av icke-derivatsäkerhet
S
Köp på öppna marknaden eller privat försäljning av icke-derivatsäkerhet
A
Bevilja, tilldelning eller annat förvärv av värdepapper från företaget (såsom en option)
C
Omvandling av derivat
D
Försäljning eller överföring av värdepapper tillbaka til företaget
F
Betalning av lösenpris eller skatteskuld med del av värdepapper som erhållits från bolaget
G
Överlåtelse av värdepapper från eller till insidern
K
Aktieswappar och liknande säkringsaffärer
M
Utövande eller omvandling av derivatsäkerhet som erhållits från företaget (som en option)
V
En transaktion friviligt rapporterad på schema 4
J
Andra (med en fotnot som beskriver transaktionen)