| Insideraktier | 21 101 487 shares |
Insider Sentiment Score
Insider sentiment score hittar de företag som köps av foretagsinsynspersoner.
Det är resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av insiderackumulation. Poängmodellen använder en kombination av nettoantalet insiders som köpt de föregående 90 dagarna, det totala antalet aktier som köpts i procent av aktiekapitalet och det totala antalet aktier som ägs av insiders. Siffran sträcker sig från 0 till 100, med högre siffror som indikerar en högre nivå av ackumulering för sina kamrater, och 50 är genomsnittet.
Uppdateringsfrekvens: Dagligen
Se Insiders Top Picks, som ger en lista över företag med högsta insiderackumulation.
Office Sentiment Score
Officersentiment Score hittar företag som köps av Corporate Officers.
Per definition Corporate Officers är Corporate Insiders, men till skillnad från vissa av de andra Insiders (10 % aktieägare och styrelseledamöter), arbetar ämbetsmän för företaget dagligen och de använder sina egna pengar när de handlar . (10 % aktieägare och styrelseledamöter är ofta fondförvaltare som förvaltar andras pengar.) Som sådan är insideraffärer som görs av tjänstemän mycket mer betydelsefulla och bör behandlas på lämpligt sätt.
Liksom Insider Sentiment Score är Officer Sentiment Score resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av officersackumulering.
Uppdateringsfrekvens: Dagligen
Se insiderns bästa val, vilket ger en lista över företag med högsta insider sentiment.
Viktiga insidernyckeltal
Denna kort visar hur företaget rankas längs olika insidernyckeltal. Procenttilrankningen visar hur detta företag jämförs med andra företag på USA-marknaden. Högre rankingar indikerar bättre situationer.
Till exempel anses det allmänt att insiderköp är en positiv indikator, så företag med mer insiderköp skulle rankas högre än företag med mindre insiderköp (eller til och med insiderförsäljning).
Nettoantalet insiders som köper (rankning)
N/A
Nettoantalet insiders som köper är den totala mängden insiders som säljer minus det totala antalet insiders som säljer under de senaste 90 dagarna. Percentilrankningen visas här (intervall från 0 till 100%).
Procent av flytande köpta av insiders (ranking)
N/A
Procentandelen av aktier köpta av insiders är det totala antalet aktier som köpts av insiders minus det totala antalet aktier som sålts av insiders under de senaste 90 dagarna, dividerat med det totala antalet aktier och multiplicerat med 100.
Insiderhandelsdiagram
Tobira Therapeutics, Inc. insideraffärer visas i följande diagram. Insiders är tjänstemän, styrelseledamöter eller betydande investerare i ett företag. I allmänhet är det i allmänhet olagligt för insiders att göra affärer i sina företag baserat på väsentlig, icke-offentlig information. Detta betyder inte att det är olagligt för dem att göra några affärer i sina egna företag. De måste dock rapportera alla affärer till SEC via ett formulär 4.
Insiderlista och lönsamhetsstatistik
Den här tabellen visar listan över kända insiders och genereras automatiskt från anmälningar som avslöjas till SEC. Förutom namnen, den senaste titeln och direktören, tjänstemannen eller ägarbeteckningen på 10 %, tillhandahåller vi de senaste avslöjade innehaven. Dessutom, när det är möjligt tillhandahåller vi insiderns historiska handelsresultat. Det historiska handelsresultatet är ett vägt genomsnitt av resultatet för faktiska köptransaktioner på den öppna marknaden som insidern gjort. För mer information om hur detta beräknas, titta på detta YouTube-webinarium.
See our leaderboard of most profitable insider traders.
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|
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Track Records av insiderköp - Kortsiktig vinstanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i TBRA / Tobira Therapeutics, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste köpen på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Track Records av insiderförsäljning - Kortsiktig förlustanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i TBRA / Tobira Therapeutics, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste försäljningarna på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Transaktionshistorik
Klicka på länkikonen för att se hela transaktionshistoriken. Transaktioner som rapporteras som en del av en automatisk handelsplan 10b5-1 kommer att ha ett X i kolumnen markerad 10b-5.
| Fil datum |
Handel datum |
Schema | Insider | Ticker | Värdepappertitel | Kod | Direkta | Utövningspris | Enhet pris |
Enheter ändrad |
Värde ändrad (1K) |
Kvarvarande Optioner |
Kvarvarande Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2016-11-04 | 2016-11-01 | 4 | DOMAIN ASSOCIATES Held by Jesse I. Treu | TBRA | Stock Option (Right to Buy) | I | 8,19 | 17 695 | 0 | |||||
| 2016-11-04 | 2016-11-01 | 4 | DOMAIN ASSOCIATES Held by Jesse I. Treu | TBRA | Stock Option (Right to Buy) | I | 42,93 | 1 071 | 0 | |||||
| 2016-11-04 | 2016-11-01 | 4 | DOMAIN ASSOCIATES Held by Jesse I. Treu | TBRA | Stock Option (Right to Buy) | I | 36,00 | 1 996 | 0 | |||||
| 2016-11-04 | 2016-11-01 | 4 | DOMAIN ASSOCIATES | TBRA | Common Stock | D | 28,3500 | −38 094 | −1 080 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | Domain Partners VI, L.P. | TBRA | Common Stock | D | 28,3500 | −285 679 | −8 099 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | DP VI Associates, L.P. | TBRA | Common Stock | D | 28,3500 | −1 657 | −47 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | WEBER ECKARD | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −17 778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | WEBER ECKARD | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | −15 500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | WEBER ECKARD | TBRA | Employee Stock Option (Right to Buy) | D | 2,96 | −4 332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | WEBER ECKARD By Eckard Weber, M.D., Trustee of the Eckard Weber Living Trust UTA dated November 20, 2007 | TBRA | Common Stock, par value $0.001 | I | −243 726 | 0 | ||||||
| 2016-11-03 | 2016-11-01 | 4 | Cooper Jeffrey H | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −17 778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Cooper Jeffrey H | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | −15 500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Cooper Jeffrey H | TBRA | Employee Stock Option (Right to Buy) | D | 8,13 | −13 539 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 8,19 | −17 695 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 34,56 | −2 947 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −53 334 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | −27 500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 42,93 | −1 071 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 36,00 | −40 733 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 40,59 | −10 253 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 105,21 | −232 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 112,77 | −232 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 112,77 | −9 314 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Frazier Healthcare V, LP | TBRA | Common Stock | D | 28,3500 | −2 668 570 | −75 654 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. | TBRA | Employee Stock Option (Right to Buy) | D | 8,19 | −17 695 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −17 778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | −15 500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. | TBRA | Employee Stock Option (Right to Buy) | D | 58,23 | −5 666 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. Held by children of Reporting Person | TBRA | Common Stock, par value $0.001 | I | −5 | 0 | ||||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. | TBRA | Common Stock, par value $0.001 | D | −11 | 0 | ||||||
| 2016-11-03 | 2016-11-01 | 4 | Heron Patrick J | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −17 778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Heron Patrick J | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | −15 500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Heron Patrick J | TBRA | Employee Stock Option (Right to Buy) | D | 2,96 | −4 332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | DP VII ASSOCIATES LP | TBRA | Common Stock | D | 28,3500 | −47 613 | −1 350 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | DOMAIN PARTERS VII L P | TBRA | Common Stock | D | 28,3500 | −3 553 322 | −100 737 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −258 000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 14,00 | −105 000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | −503 882 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | −83 324 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 3,14 | −16 416 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 3,14 | −53 616 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 3,14 | −4 332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 2,96 | −4 332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Legault Pierre | TBRA | Employee Stock Option (Right to Buy) | D | 8,19 | −17 695 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Legault Pierre | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −17 778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Legault Pierre | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | −15 500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Legault Pierre | TBRA | Employee Stock Option (Right to Buy) | D | 42,93 | −535 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Legault Pierre | TBRA | Employee Stock Option (Right to Buy) | D | 43,83 | −6 111 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Brosgart Carol L | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −17 778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Brosgart Carol L | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | −15 500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Brosgart Carol L | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | −18 956 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Brosgart Carol L | TBRA | Employee Stock Option (Right to Buy) | D | 4,25 | −4 332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Brosgart Carol L | TBRA | Employee Stock Option (Right to Buy) | D | 3,14 | −4 332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Jenkins Helen | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −101 000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Jenkins Helen | TBRA | Employee Stock Option (Right to Buy) | D | 14,00 | −65 000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Jenkins Helen | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | −29 841 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Jenkins Helen | TBRA | Employee Stock Option (Right to Buy) | D | 3,51 | −29 548 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Peetz Christopher | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −101 000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Peetz Christopher | TBRA | Employee Stock Option (Right to Buy) | D | 14,00 | −85 000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Peetz Christopher | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | −31 091 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Peetz Christopher | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | −68 732 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Lefebvre Eric | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −101 000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Lefebvre Eric | TBRA | Employee Stock Option (Right to Buy) | D | 14,00 | −100 000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Lefebvre Eric | TBRA | Employee Stock Option (Right to Buy) | D | 3,51 | −79 287 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Melincoff Gwen A | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | −17 778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Melincoff Gwen A | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | −15 500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Melincoff Gwen A | TBRA | Employee Stock Option (Right to Buy) | D | 8,13 | −13 539 | 0 | |||||
| 2016-11-02 | 2016-10-31 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 42,1000 | 5 000 | 210 | 3 758 200 | ||||
| 2016-11-02 | 2016-10-31 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 41,7100 | 10 000 | 417 | 3 753 200 | ||||
| 2016-10-19 | 2016-10-18 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 40,0400 | 8 300 | 332 | 3 743 200 | ||||
| 2016-10-19 | 2016-10-17 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 40,1000 | 27 400 | 1 099 | 3 734 900 | ||||
| 2016-10-19 | 2016-10-17 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,8900 | 4 300 | 172 | 3 707 500 | ||||
| 2016-10-06 | 2016-10-04 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,8300 | 4 481 | 178 | 3 703 200 | ||||
| 2016-09-30 | 2016-09-29 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,4900 | 9 019 | 356 | 3 698 719 | ||||
| 2016-09-30 | 2016-09-29 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,4900 | 6 500 | 257 | 3 689 700 | ||||
| 2016-09-29 | 3 | Sapphire Acquisition Corp. See Footnotes | TBRA | Common Stock, par value $0.001 | I | 0 | ||||||||
| 2016-09-28 | 2016-09-26 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,0000 | 49 400 | 1 927 | 3 683 200 | ||||
| 2016-09-28 | 2016-09-26 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,0100 | 600 | 23 | 3 633 800 | ||||
| 2016-09-23 | 2016-09-23 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,0900 | 5 000 | 195 | 3 633 200 | ||||
| 2016-09-23 | 2016-09-23 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,1900 | 95 000 | 3 723 | 3 628 200 | ||||
| 2016-09-22 | 3 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 3 818 000 | ||||||||
| 2016-09-22 | 3 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 3 818 000 | ||||||||
| 2016-09-22 | 2016-09-22 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,4500 | 20 000 | 789 | 3 533 200 | ||||
| 2016-09-22 | 2016-09-22 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,4000 | 27 791 | 1 095 | 3 513 200 | ||||
| 2016-09-22 | 2016-09-22 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,3000 | 50 000 | 1 965 | 3 485 409 | ||||
| 2016-09-22 | 2016-09-22 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,2600 | 1 209 | 47 | 3 435 409 | ||||
| 2016-09-22 | 2016-09-21 | 4 | Pentwater Capital Management LP By Matthew Halbower | TBRA | Common Stock, par value $0.001 per share | I | 39,1400 | 195 000 | 7 632 | 3 434 200 | ||||
| 2016-09-22 | 2016-09-21 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 38,9700 | 31 000 | 1 208 | 3 239 200 | ||||
| 2016-09-22 | 2016-09-21 | 4 | Pentwater Capital Management LP By David Pickering | TBRA | Common Stock, par value $0.001 per share | I | 39,1200 | 3 200 | 125 | 3 208 200 | ||||
| 2016-09-22 | 2016-09-20 | 4 | Pentwater Capital Management LP By Matthew Halbower | TBRA | Common Stock, par value $0.001 per share | I | 39,0700 | 5 000 | 195 | 3 205 000 | ||||
| 2016-09-22 | 2016-09-20 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 38,8700 | 220 000 | 8 551 | 3 200 000 | ||||
| 2016-09-22 | 2016-09-20 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,2300 | 1 000 | 39 | 2 980 000 | ||||
| 2016-09-22 | 2016-09-20 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,0300 | 1 070 000 | 41 762 | 2 979 000 | ||||
| 2016-07-13 | 2016-07-13 | 4 | Novo A/S | TBRA | Common Stock | D | 11,8774 | −29 884 | −355 | 1 875 905 | ||||
| 2016-07-13 | 2016-07-12 | 4 | Novo A/S | TBRA | Common Stock | D | 12,1198 | −8 752 | −106 | 1 905 789 | ||||
| 2016-07-13 | 2016-07-11 | 4 | Novo A/S | TBRA | Common Stock | D | 12,1923 | −20 431 | −249 | 1 914 541 | ||||
| 2016-07-07 | 2016-07-07 | 4 | Novo A/S | TBRA | Common Stock | D | 12,0330 | −21 869 | −263 | 1 934 972 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Novo A/S | TBRA | Common Stock | D | 12,2017 | −59 850 | −730 | 1 956 841 | ||||
| 2016-07-07 | 2016-07-05 | 4 | Novo A/S | TBRA | Common Stock | D | 12,5682 | −10 400 | −131 | 2 016 691 | ||||
| 2016-06-30 | 2016-06-30 | 4 | Novo A/S | TBRA | Common Stock | D | 12,5813 | −27 133 | −341 | 2 027 091 | ||||
| 2016-06-30 | 2016-06-29 | 4 | Novo A/S | TBRA | Common Stock | D | 12,6305 | −16 068 | −203 | 2 054 224 | ||||
| 2016-06-30 | 2016-06-28 | 4 | Novo A/S | TBRA | Common Stock | D | 14,2765 | −2 730 | −39 | 2 070 292 | ||||
| 2016-06-30 | 2016-06-28 | 4 | Novo A/S | TBRA | Common Stock | D | 13,7744 | −20 883 | −288 | 2 073 022 | ||||
| 2016-06-07 | 2016-06-06 | 4 | Novo A/S | TBRA | Common Stock | D | 10,3675 | −187 500 | −1 944 | 2 093 905 | ||||
| 2016-03-04 | 2016-03-04 | 4 | Novo A/S | TBRA | Common Stock | D | 6,5394 | −55 000 | −360 | 2 281 405 | ||||
| 2016-03-04 | 2016-03-03 | 4 | Novo A/S | TBRA | Common Stock | D | 6,8558 | −25 000 | −171 | 2 336 405 | ||||
| 2016-03-04 | 2016-03-02 | 4 | Novo A/S | TBRA | Common Stock | D | 6,9184 | −110 000 | −761 | 2 361 405 | ||||
| 2016-01-14 | 2016-01-12 | 4 | Jenkins Helen | TBRA | Stock Options (right to buy) | D | 7,91 | 101 000 | 101 000 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Peetz Christopher | TBRA | Stock Options (right to buy) | D | 7,91 | 101 000 | 101 000 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Lefebvre Eric | TBRA | Stock Options (right to buy) | D | 7,91 | 101 000 | 101 000 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 7,91 | 258 000 | 258 000 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Melincoff Gwen A | TBRA | Stock Options (right to buy) | D | 7,91 | 17 778 | 17 778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 7,91 | 17 778 | 17 778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Heron Patrick J | TBRA | Stock Options (right to buy) | D | 7,91 | 17 778 | 17 778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Fromkin Andrew J. | TBRA | Stock Options (right to buy) | D | 7,91 | 17 778 | 17 778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Legault Pierre | TBRA | Stock Options (right to buy) | D | 7,91 | 17 778 | 17 778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Podlesak Dennis | TBRA | Stock Options (right to buy) | D | 7,91 | 53 334 | 53 334 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Cooper Jeffrey H | TBRA | Stock Options (right to buy) | D | 7,91 | 17 778 | 17 778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | WEBER ECKARD | TBRA | Stock Options (right to buy) | D | 7,91 | 17 778 | 17 778 | |||||
| 2015-12-18 | 3 | Shah Nimesh By Domain Associates, LLC | TBRA | Common Stock | I | 76 188 | ||||||||
| 2015-12-18 | 3 | Shah Nimesh By Domain Associates, LLC | TBRA | Common Stock | I | 76 188 | ||||||||
| 2015-11-19 | 2015-11-18 | 4 | Novo A/S | TBRA | Common Stock | D | 9,7570 | −153 601 | −1 499 | 2 471 405 | ||||
| 2015-11-19 | 2015-11-17 | 4 | Novo A/S | TBRA | Common Stock | D | 9,8656 | −71 399 | −704 | 2 625 006 | ||||
| 2015-07-13 | 2015-07-09 | 4 | Podlesak Dennis | TBRA | Stock Options (right to buy) | D | 16,52 | 27 500 | 27 500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Fromkin Andrew J. | TBRA | Stock Options (right to buy) | D | 16,52 | 15 500 | 15 500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Legault Pierre | TBRA | Stock Options (right to buy) | D | 16,52 | 15 500 | 15 500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Melincoff Gwen A | TBRA | Stock Options (right to buy) | D | 16,52 | 15 500 | 15 500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 16,52 | 15 500 | 15 500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Heron Patrick J | TBRA | Stock Options (right to buy) | D | 16,52 | 15 500 | 15 500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Cooper Jeffrey H | TBRA | Stock Options (right to buy) | D | 16,52 | 15 500 | 15 500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | WEBER ECKARD | TBRA | Stock Options (right to buy) | D | 16,52 | 15 500 | 15 500 | |||||
| 2015-05-18 | 2015-05-15 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 14,00 | 105 000 | 105 000 | |||||
| 2015-05-18 | 2015-05-15 | 4 | Jenkins Helen | TBRA | Stock Options (right to buy) | D | 14,00 | 65 000 | 65 000 | |||||
| 2015-05-18 | 2015-05-15 | 4 | Peetz Christopher | TBRA | Stock Options (right to buy) | D | 14,00 | 85 000 | 85 000 | |||||
| 2015-05-18 | 2015-05-15 | 4 | Lefebvre Eric | TBRA | Stock Options (right to buy) | D | 14,00 | 100 000 | 100 000 | |||||
| 2015-05-07 | 2015-05-04 | 4/A | WEBER ECKARD | TBRA | Stock Options (right to buy) | D | 2,96 | 4 332 | 4 332 | |||||
| 2015-05-07 | 2015-05-04 | 4/A | WEBER ECKARD By Eckard Weber, M.D., Trustee of the Eckard Weber Living Trust UTA dated November 20, 2007 | TBRA | Common Stock | I | 243 726 | 243 726 | ||||||
| 2015-05-07 | 3 | WEBER ECKARD | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-07 | 2015-05-04 | 4 | WEBER ECKARD | TBRA | Stock Options (right to buy) | D | 2,96 | 4 332 | 4 332 | |||||
| 2015-05-07 | 2015-05-04 | 4 | WEBER ECKARD By DP VII Associates, L.P. | TBRA | Common Stock | I | 47 613 | 47 613 | ||||||
| 2015-05-07 | 2015-05-04 | 4 | WEBER ECKARD By Domain Partners VII, L.P. | TBRA | Common Stock | I | 3 553 322 | 3 553 322 | ||||||
| 2015-05-07 | 2015-05-04 | 4 | WEBER ECKARD By Domain Associates, L.L.C. | TBRA | Common Stock | I | 36 187 | 36 187 | ||||||
| 2015-05-07 | 2015-05-04 | 4 | WEBER ECKARD By Eckard Weber, M.D., Trustee of the Eckard Weber Living Trust UTA dated November 20, 2007 | TBRA | Common Stock | I | 243 726 | 243 726 | ||||||
| 2015-05-06 | 3 | Peetz Christopher | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Fischer Laurent | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Frazier Healthcare V, LP | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Lefebvre Eric | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Brosgart Carol L | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Melincoff Gwen A | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Jenkins Helen | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Novo A/S | TBRA | COMMON STOCK | D | 3 716 728 | ||||||||
| 2015-05-06 | 3 | Novo A/S | TBRA | COMMON STOCK | D | 3 716 728 | ||||||||
| 2015-05-06 | 3 | Cooper Jeffrey H | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Heron Patrick J | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95 226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95 226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95 226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95 226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95 226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95 226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95 226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95 226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6 551 090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6 551 090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6 551 090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6 551 090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6 551 090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6 551 090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6 551 090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6 551 090 | ||||||||
| 2015-05-06 | 2015-05-04 | 4 | Cooper Jeffrey H | TBRA | Stock Options (right to buy) | D | 8,13 | 13 539 | 13 539 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Frazier Healthcare V, LP | TBRA | Common Stock | D | 2 668 570 | 2 668 570 | ||||||
| 2015-05-06 | 2015-05-04 | 4 | Heron Patrick J | TBRA | Stock Option (right to buy) | D | 2,96 | 4 332 | 4 332 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Heron Patrick J By Frazier Healthcare V, LP | TBRA | Common Stock | I | 2 668 570 | 2 668 570 | ||||||
| 2015-05-06 | 2015-05-04 | 4 | DOMAIN PARTERS VII L P | TBRA | Common Stock | D | 10,6200 | 277 777 | 2 950 | 3 553 322 | ||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 4,81 | 503 882 | 672 671 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 4,81 | 83 324 | 168 789 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 3,51 | 6 769 | 85 465 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 3,14 | 16 416 | 78 696 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 3,14 | 53 616 | 62 280 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 2,96 | 4 332 | 8 664 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 3,14 | 4 332 | 8 664 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Novo A/S | TBRA | COMMON STOCK | D | 10,6200 | 838 041 | 8 900 | 2 696 405 | ||||
| 2015-05-06 | 2015-05-04 | 4 | DOMAIN ASSOCIATES | TBRA | Common Stock | D | 36 187 | 38 094 | ||||||
| 2015-05-06 | 2015-05-04 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 4,81 | 18 956 | 31 952 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 4,25 | 4 332 | 12 996 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 3,51 | 4 332 | 12 996 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 3,14 | 4 332 | 8 664 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Jenkins Helen | TBRA | Stock Options (right to buy) | D | 4,81 | 29 841 | 75 700 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Jenkins Helen | TBRA | Stock Options (right to buy) | D | 3,51 | 16 311 | 45 859 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Jenkins Helen | TBRA | Stock Options (right to buy) | D | 3,51 | 29 548 | 29 548 | |||||
| 2015-05-06 | 2015-05-06 | 4 | Peetz Christopher | TBRA | Stock Options | D | 4,81 | 31 091 | 99 823 | |||||
| 2015-05-06 | 2015-05-06 | 4 | Peetz Christopher | TBRA | Stock Options (right to buy) | D | 4,81 | 68 732 | 68 732 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Lefebvre Eric | TBRA | Stock Options (right to buy) | D | 3,51 | 21 607 | 100 894 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Lefebvre Eric | TBRA | Stock Options (right to buy) | D | 3,51 | 79 287 | 79 287 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Melincoff Gwen A | TBRA | Stock Options (right to buy) | D | 8,13 | 13 539 | 13 539 | |||||
| 2015-02-20 | 2014-12-03 | 4/A | Metzger Michael A | RGDO | Stock Option (right to buy) | D | 0,84 | 837 531 | 837 531 | |||||
| 2015-01-06 | 2015-01-01 | 4 | NEFF P SHERRILL | RGDO | Common Stock (right to buy) | D | 0,91 | 159 261 | 159 261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Clark B. Jefferson | RGDO | Common Stock (right to buy) | D | 0,91 | 159 261 | 159 261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Elsey R Don | RGDO | Common Stock (right to buy) | D | 0,91 | 92 902 | 92 902 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Legault Pierre | RGDO | Common Stock (right to buy) | D | 0,91 | 159 261 | 159 261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Podlesak Dennis | RGDO | Common Stock (right to buy) | D | 0,91 | 159 261 | 159 261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Gopka Anton | RGDO | Common Stock (right to buy) | D | 0,91 | 159 261 | 159 261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Mendelsohn Michael | RGDO | Common Stock (right to buy) | D | 0,91 | 159 261 | 159 261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Fromkin Andrew J. | RGDO | Common Stock (right to buy) | D | 0,91 | 159 261 | 159 261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | TREU JESSE I | RGDO | Stock Option (right to buy) | D | 0,91 | 159 261 | 159 261 | |||||
| 2014-12-24 | 2014-10-28 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 1,1000 | −941 252 | −1 035 | 3 214 955 | ||||
| 2014-12-24 | 2014-10-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 1,0800 | −18 748 | −20 | 4 156 207 | ||||
| 2014-12-24 | 2014-10-24 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 1,1000 | −100 000 | −110 | 4 174 955 | ||||
| 2014-12-24 | 2014-10-24 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 1,0600 | −10 000 | −11 | 4 274 955 | ||||
| 2014-12-05 | 2014-12-03 | 4 | Metzger Michael A | RGDO | Stock Option (right to buy) | D | 0,85 | 837 531 | 837 531 | |||||
| 2014-06-16 | 3 | Fromkin Andrew J. [by his children] | RGDO | Common Stock | I | 200 | ||||||||
| 2014-06-16 | 3 | Fromkin Andrew J. | RGDO | Common Stock | D | 250 | ||||||||
| 2014-06-16 | 3 | Fromkin Andrew J. | RGDO | Common Stock | D | 250 | ||||||||
| 2014-06-16 | 3 | Fromkin Andrew J. [by his children] | RGDO | Common Stock | I | 200 | ||||||||
| 2014-06-16 | 2014-06-12 | 4 | Fromkin Andrew J. | RGDO | Stock Option (right to buy) | D | 6,47 | 51 000 | 51 000 | |||||
| 2014-05-21 | 3 | Pelliccione Nicholas J. | RGDO | No securities are beneficially owned | D | 0 | ||||||||
| 2014-05-21 | 2014-05-21 | 4 | Pelliccione Nicholas J. | RGDO | Stock Option (right to buy) | D | 5,46 | 100 000 | 100 000 | |||||
| 2014-05-07 | 3 | Elsey R Don | RGDO | No securities are beneficially owned | D | 0 | ||||||||
| 2014-05-07 | 2014-05-05 | 4 | Elsey R Don | RGDO | Stock Option (right to buy) | D | 6,36 | 250 000 | 250 000 | |||||
| 2014-04-17 | 2014-04-16 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 6,0000 | 575 000 | 3 450 | 4 284 955 | ||||
| 2014-03-25 | 2014-03-21 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | RGDO | Preferred Stock, $0.001 per share | I | 5,00 | 2 632 | 2 632 | |||||
| 2014-03-25 | 2014-03-21 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | RGDO | Preferred Stock, $0.001 per share | I | 5,00 | 4 577 | 4 577 | |||||
| 2014-03-25 | 2014-03-21 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | RGDO | Common Stock, $0.001 par value | I | −526 436 | 1 121 221 | ||||||
| 2014-03-25 | 2014-03-21 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | RGDO | Common Stock, $0.001 par value | I | −915 345 | 1 979 670 | ||||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Stock Option (right to buy) | I | 3,34 | −1 | 0 | |||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Warrant (right to buy) | I | 0,17 | −1 | 0 | |||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Stock Option (right to buy) | I | 4,51 | −1 | 0 | |||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Stock Option (right to buy) | I | 4,51 | −1 | 0 | |||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Common Stock, par value $0.001 per share | I | 0,1700 | 4 491 | 1 | 1 130 133 | ||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Common Stock, par value $0.001 per share | I | 4,5100 | 3 341 | 15 | 1 125 642 | ||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Common Stock, par value $0.001 per share | I | 4,5100 | 5 447 | 25 | 1 122 301 | ||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Common Stock, par value $0.001 per share | I | 3,3400 | 2 095 | 7 | 1 116 854 | ||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4 222 129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5 080 487 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4 222 129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5 080 487 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5 080 487 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5 080 487 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4 222 129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4 222 129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5 080 487 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4 222 129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4 222 129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5 080 487 | ||||||||
| 2014-02-06 | 2014-02-05 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 5,0000 | 400 000 | 2 000 | 3 700 955 | ||||
| 2014-01-03 | 2014-01-01 | 4 | TREU JESSE I | RGDO | Stock Option (right to buy) | D | 4,77 | 9 640 | 9 640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | NEFF P SHERRILL | RGDO | Stock Option (right to buy) | D | 4,77 | 9 640 | 9 640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Legault Pierre | RGDO | Stock Option (right to buy) | D | 4,77 | 4 820 | 4 820 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Podlesak Dennis | RGDO | Stock Option (right to buy) | D | 4,77 | 9 640 | 9 640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Mazzo David J | RGDO | Stock Option (right to buy) | D | 4,77 | 180 000 | 180 000 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Clark B. Jefferson | RGDO | Stock Option (right to buy) | D | 4,77 | 9 640 | 9 640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Rusconi Christopher Paul | RGDO | Stock Option (right to buy) | D | 4,77 | 73 000 | 73 000 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Gopka Anton | RGDO | Stock Option (right to buy) | D | 4,77 | 9 640 | 9 640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Wisniewski Raphael | RGDO | Stock Option (right to buy) | D | 4,77 | 9 640 | 9 640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Courts Christopher | RGDO | Stock Option (right to buy) | D | 4,77 | 23 000 | 23 000 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Zelenkofske Steven | RGDO | Stock Option (right to buy) | D | 4,77 | 75 000 | 75 000 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Giaquinto Alexander R | RGDO | Stock Option (right to buy) | D | 4,77 | 38 000 | 38 000 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Mendelsohn Michael | RGDO | Stock Option (right to buy) | D | 4,77 | 4 820 | 4 820 | |||||
| 2013-12-20 | 2013-12-16 | 4 | Metzger Michael A | RGDO | Stock Option (right to buy) | D | 4,81 | 434 008 | 434 008 | |||||
| 2013-08-30 | 2013-08-27 | 4/A | RMI Investments S.a.r.l. | RGDO | Series E Preferred Stock | D | −22 878 805 | 0 | ||||||
| 2013-08-30 | 2013-08-27 | 4/A | RMI Investments S.a.r.l. | RGDO | Common Stock, par value $0.001 per share | D | 4,0000 | 3 866 529 | 15 466 | 5 236 517 | ||||
| 2013-08-30 | 2013-08-27 | 4/A | RMI Investments S.a.r.l. | RGDO | Common Stock, par value $0.001 per share | D | 1 369 988 | 1 369 988 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Series E Preferred Stock | D | −807 652 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Series D Preferred Stock | D | −7 769 715 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Series C Preferred Stock | D | −4 566 908 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Series B Preferred Stock | D | −6 666 667 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Common Stock, par value $0.001 per share | D | 4,0000 | 71 810 | 287 | 1 294 021 | ||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Common Stock, par value $0.001 per share | D | 48 362 | 1 222 211 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Common Stock, par value $0.001 per share | D | 465 252 | 1 173 849 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Common Stock, par value $0.001 per share | D | 273 468 | 708 597 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Common Stock, par value $0.001 per share | D | 399 201 | 435 129 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Series E Preferred Stock | I | −807 652 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Series D Preferred Stock | I | −7 769 715 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Series C Preferred Stock | I | −4 566 908 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Series B Preferred Stock | I | −6 666 667 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL | RGDO | Stock Option (right to buy) | D | 4,00 | 17 964 | 17 964 | |||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Common Stock, par value $0.001 per share | I | 4,0000 | 71 810 | 287 | 1 294 021 | ||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Common Stock, par value $0.001 per share | I | 48 362 | 1 222 211 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Common Stock, par value $0.001 per share | I | 465 252 | 1 173 849 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Common Stock, par value $0.001 per share | I | 273 468 | 708 597 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Common Stock, par value $0.001 per share | I | 399 201 | 435 129 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Podlesak Dennis | RGDO | Stock Option (right to buy) | D | 4,00 | 366 605 | 366 605 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Mazzo David J | RGDO | Stock Option (right to buy) | D | 4,00 | 558 167 | 558 167 | |||||
| 2013-08-29 | 2013-08-27 | 4 | McDonald Ellen | RGDO | Stock Option (right to buy) | D | 4,00 | 51 092 | 51 092 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Series E Preferred Stock | I | −807 652 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Series D Preferred Stock | I | 5 376 964 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Series C Preferred Stock | I | −2 222 222 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Series B Preferred Stock | I | −1 458 333 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Series A Preferred Stock | I | −2 428 367 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson | RGDO | Stock Option (right to buy) | D | 4,00 | 17 964 | 17 964 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 8 | RGDO | Common Stock, par value $0.001 per share | I | 4,0000 | 359 310 | 1 437 | 1 114 759 | ||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Common Stock, par value $0.001 per share | I | 48 362 | 755 449 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Common Stock, par value $0.001 per share | I | 321 973 | 707 087 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Common Stock, par value $0.001 per share | I | 133 067 | 385 114 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Common Stock, par value $0.001 per share | I | 87 325 | 252 047 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Common Stock, par value $0.001 per share | I | 145 411 | 164 722 | ||||||
| 2013-08-29 | 2023-08-27 | 4 | Wisniewski Raphael | RGDO | Stock Option (right to buy) | D | 4,00 | 17 964 | 17 964 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Wisniewski Raphael See Footnote 4 | RGDO | Series E Preferred Stock | I | −2 832 872 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Wisniewski Raphael See Footnote 4 | RGDO | Series D Preferred Stock | I | −17 066 243 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Wisniewski Raphael See Footnote 4 | RGDO | Common Stock, par value $0.001 per share | I | 4,0000 | 1 215 708 | 4 863 | 2 407 271 | ||||
| 2013-08-29 | 2013-08-27 | 4 | Wisniewski Raphael See Footnote 4 | RGDO | Common Stock, par value $0.001 per share | I | 169 633 | 1 191 563 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Wisniewski Raphael See Footnote 4 | RGDO | Common Stock, par value $0.001 per share | I | 1 021 930 | 1 021 930 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Giaquinto Alexander R | RGDO | Stock Option (right to buy) | D | 4,00 | 29 929 | 29 929 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Zelenkofske Steven | RGDO | Stock Option (right to buy) | D | 4,00 | 225 552 | 225 552 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Courts Christopher | RGDO | Series E Preferred Stock | D | −90 277 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Courts Christopher | RGDO | Stock Option (right to buy) | D | 4,00 | 25 965 | 25 965 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Courts Christopher | RGDO | Common Stock, par value $0.001 per share | D | 5 405 | 5 405 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Rusconi Christopher Paul | RGDO | Stock Option (right to buy) | D | 4,00 | 59 880 | 59 880 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Gopka Anton See Footnote 3 | RGDO | Series E Preferred Stock | I | −22 878 805 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Gopka Anton | RGDO | Stock Option (right to buy) | D | 4,00 | 17 964 | 17 964 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Gopka Anton See Footnote 3 | RGDO | Common Stock, par value $0.001 per share | I | 4,0000 | 3 866 529 | 15 466 | 5 236 517 | ||||
| 2013-08-29 | 2013-08-27 | 4 | Gopka Anton See Footnote 3 | RGDO | Common Stock, par value $0.001 per share | I | 1 369 988 | 1 369 988 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | BIODISCOVERY 3, FCPR | RGDO | Series E Preferred Stock | D | −2 832 872 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | BIODISCOVERY 3, FCPR | RGDO | Series D Preferred Stock | D | −17 066 243 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | BIODISCOVERY 3, FCPR | RGDO | Common Stock, par value $0.001 per share | D | 4,0000 | 1 215 708 | 4 863 | 2 407 271 | ||||
| 2013-08-29 | 2013-08-27 | 4 | BIODISCOVERY 3, FCPR | RGDO | Common Stock, par value $0.001 per share | D | 169 633 | 1 191 563 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | BIODISCOVERY 3, FCPR | RGDO | Common Stock, par value $0.001 per share | D | 1 021 930 | 1 021 930 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | RMI Investments S.a.r.l. | RGDO | Series E Preferred Stock | D | −22 878 805 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | RMI Investments S.a.r.l. | RGDO | Common Stock, par value $0.001 per share | D | 4,0000 | 3 866 529 | 15 466 | 5 236 517 | ||||
| 2013-08-29 | 2013-08-27 | 4 | RMI Investments S.a.r.l. | RGDO | Common Stock, par value $0.001 per share | D | 1 369 988 | 1 369 988 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Series E Preferred Stock | D | −10 750 105 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Series D Preferred Stock | D | −23 261 013 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Series C Preferred Stock | D | −3 324 136 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Series B Preferred Stock | D | −1 670 833 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Series A Preferred Stock | D | −3 369 811 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 4,0000 | 750 000 | 3 000 | 3 300 955 | ||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 634 718 | 2 550 955 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 1 392 875 | 1 916 237 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 199 050 | 523 362 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 100 050 | 324 312 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 201 785 | 224 262 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | D | −225 913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | D | −894 120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | D | −270 568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | D | −394 969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 4,0000 | 750 000 | 3 000 | 2 571 117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 225 913 | 1 821 117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 894 120 | 1 595 204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 270 568 | 701 084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 394 969 | 430 516 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Series D Preferred Stock | D | −7 407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Series C Preferred Stock | D | −2 899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Series B Preferred Stock | D | −4 233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Common Stock | D | 7 407 | 14 920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Common Stock | D | 2 899 | 7 513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Common Stock | D | 4 233 | 4 614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Series D Preferred Stock | I | −7 407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Series C Preferred Stock | I | −2 899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Series B Preferred Stock | I | −4 233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | I | −225 913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | I | −894 120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | I | −270 568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | I | −394 969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Common Stock | I | 7 407 | 14 920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Common Stock | I | 2 899 | 7 513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Common Stock | I | 4 233 | 4 614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 4,0000 | 750 000 | 3 000 | 2 571 117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 225 913 | 1 821 117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 894 120 | 1 595 204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 270 568 | 701 084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 394 969 | 430 516 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Series D Preferred Stock | I | −7 407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Series C Preferred Stock | I | −2 899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Series B Preferred Stock | I | −4 233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | I | −225 913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | I | −894 120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | I | −270 568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | I | −394 969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Common Stock | I | 7 407 | 14 920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Common Stock | I | 2 899 | 7 513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Common Stock | I | 4 233 | 4 614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 4,0000 | 750 000 | 3 000 | 2 571 117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 225 913 | 1 821 117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 894 120 | 1 595 204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 270 568 | 701 084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 394 969 | 430 516 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Series D Preferred Stock | I | −7 407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Series C Preferred Stock | I | −2 899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Series B Preferred Stock | I | −4 233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | I | −225 913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | I | −894 120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | I | −270 568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | I | −394 969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Common Stock | I | 7 407 | 14 920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Common Stock | I | 2 899 | 7 513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Common Stock | I | 4 233 | 4 614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 4,0000 | 750 000 | 3 000 | 2 571 117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 225 913 | 1 821 117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 894 120 | 1 595 204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 270 568 | 701 084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 394 969 | 430 516 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I | RGDO | Stock Option (right to buy) | D | 4,00 | 17 964 | 17 964 | |||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Series D Preferred Stock | I | −7 407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Series C Preferred Stock | I | −2 899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Series B Preferred Stock | I | −4 233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | I | −225 913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | I | −894 120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | I | −270 568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | I | −394 969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Common Stock | I | 7 407 | 14 920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Common Stock | I | 2 899 | 7 513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Common Stock | I | 4 233 | 4 614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 4,0000 | 750 000 | 3 000 | 2 571 117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 225 913 | 1 821 117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 894 120 | 1 595 204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 270 568 | 701 084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 394 969 | 430 516 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Series D Preferred Stock | I | −7 407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Series C Preferred Stock | I | −2 899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Series B Preferred Stock | I | −4 233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | I | −225 913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | I | −894 120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | I | −270 568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | I | −394 969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Common Stock | I | 7 407 | 14 920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Common Stock | I | 2 899 | 7 513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Common Stock | I | 4 233 | 4 614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 4,0000 | 750 000 | 3 000 | 2 571 117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 225 913 | 1 821 117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 894 120 | 1 595 204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 270 568 | 701 084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 394 969 | 430 516 | ||||||
| 2013-08-21 | 3 | BLAIR JAMES C By Domain Associates, LLC | RGDO | Common Stock | I | 17 171 | ||||||||
| 2013-08-21 | 3 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Common Stock | I | 381 | ||||||||
| 2013-08-21 | 3 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 35 547 | ||||||||
| 2013-08-21 | 3 | DOMAIN ASSOCIATES | RGDO | Common Stock | D | 17 171 | ||||||||
| 2013-08-21 | 3 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Common Stock | I | 381 | ||||||||
| 2013-08-21 | 3 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 35 547 | ||||||||
| 2013-08-21 | 3 | DOVEY BRIAN H By Domain Associates, LLC | RGDO | Common Stock | I | 17 171 | ||||||||
| 2013-08-21 | 3 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 35 547 | ||||||||
| 2013-08-21 | 3 | DP VI Associates, L.P. | RGDO | Common Stock | D | 381 | ||||||||
| 2013-08-21 | 3 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 35 547 | ||||||||
| 2013-08-21 | 3 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Common Stock | I | 381 | ||||||||
| 2013-08-21 | 3 | SCHOEMAKER KATHLEEN K By Domain Associates, LLC | RGDO | Common Stock | I | 17 171 | ||||||||
| 2013-08-21 | 3 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 35 547 | ||||||||
| 2013-08-21 | 3 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Common Stock | I | 381 | ||||||||
| 2013-08-21 | 3 | TREU JESSE I By Domain Associates, LLC | RGDO | Common Stock | I | 17 171 | ||||||||
| 2013-08-21 | 3 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Common Stock | I | 381 | ||||||||
| 2013-08-21 | 3 | VITULLO NICOLE By Domain Associates, LLC | RGDO | Common Stock | I | 17 171 | ||||||||
| 2013-08-21 | 3 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 35 547 | ||||||||
| 2013-08-21 | 3 | NEFF P SHERRILL | RGDO | Common Stock, par value $0.001 per share | I | 35 928 | ||||||||
| 2013-08-21 | 3 | QUAKER BIOVENTURES CAPITAL LP | RGDO | Common Stock, par value $0.001 per share | D | 35 928 | ||||||||
| 2013-08-21 | 3 | Halak Brian K By Domain Associates, LLC | RGDO | Common Stock | I | 17 171 | ||||||||
| 2013-08-21 | 3 | Clark B. Jefferson See Footnote 1 | RGDO | Common Stock, par value $0.001 per share | I | 19 311 | ||||||||
| 2013-08-21 | 3 | Kamdar Kim P. By Domain Associates, LLC | RGDO | Common Stock | I | 17 171 | ||||||||
| 2013-08-21 | 3 | Rusconi Christopher Paul | RGDO | Common Stock, par value $0.001 per share | D | 22 904 | ||||||||
| 2013-08-21 | 3 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 22 478 |
P
Köp på öppna marknaden eller privat köp av icke-derivatsäkerhet
S
Köp på öppna marknaden eller privat försäljning av icke-derivatsäkerhet
A
Bevilja, tilldelning eller annat förvärv av värdepapper från företaget (såsom en option)
C
Omvandling av derivat
D
Försäljning eller överföring av värdepapper tillbaka til företaget
F
Betalning av lösenpris eller skatteskuld med del av värdepapper som erhållits från bolaget
G
Överlåtelse av värdepapper från eller till insidern
K
Aktieswappar och liknande säkringsaffärer
M
Utövande eller omvandling av derivatsäkerhet som erhållits från företaget (som en option)
V
En transaktion friviligt rapporterad på schema 4
J
Andra (med en fotnot som beskriver transaktionen)
