MDCO Insider Trading - Medicines Company

Insideraktier

2 021 521 shares

Insider Sentiment Score

Insider sentiment score hittar de företag som köps av foretagsinsynspersoner.

Det är resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av insiderackumulation. Poängmodellen använder en kombination av nettoantalet insiders som köpt de föregående 90 dagarna, det totala antalet aktier som köpts i procent av aktiekapitalet och det totala antalet aktier som ägs av insiders. Siffran sträcker sig från 0 till 100, med högre siffror som indikerar en högre nivå av ackumulering för sina kamrater, och 50 är genomsnittet.

Uppdateringsfrekvens: Dagligen

Se Insiders Top Picks, som ger en lista över företag med högsta insiderackumulation.

Se Högst rankade aktier

Office Sentiment Score

Officersentiment Score hittar företag som köps av Corporate Officers.

Per definition Corporate Officers är Corporate Insiders, men till skillnad från vissa av de andra Insiders (10 % aktieägare och styrelseledamöter), arbetar ämbetsmän för företaget dagligen och de använder sina egna pengar när de handlar . (10 % aktieägare och styrelseledamöter är ofta fondförvaltare som förvaltar andras pengar.) Som sådan är insideraffärer som görs av tjänstemän mycket mer betydelsefulla och bör behandlas på lämpligt sätt.

Liksom Insider Sentiment Score är Officer Sentiment Score resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av officersackumulering.

Uppdateringsfrekvens: Dagligen

Se insiderns bästa val, vilket ger en lista över företag med högsta insider sentiment.

Se Högst rankade aktier

Viktiga insidernyckeltal

Denna kort visar hur företaget rankas längs olika insidernyckeltal. Procenttilrankningen visar hur detta företag jämförs med andra företag på USA-marknaden. Högre rankingar indikerar bättre situationer.

Till exempel anses det allmänt att insiderköp är en positiv indikator, så företag med mer insiderköp skulle rankas högre än företag med mindre insiderköp (eller til och med insiderförsäljning).

Nettoantalet insiders som köper (rankning)

N/A

Nettoantalet insiders som köper är den totala mängden insiders som säljer minus det totala antalet insiders som säljer under de senaste 90 dagarna. Percentilrankningen visas här (intervall från 0 till 100%).

Procent av flytande köpta av insiders (ranking)

N/A

Procentandelen av aktier köpta av insiders är det totala antalet aktier som köpts av insiders minus det totala antalet aktier som sålts av insiders under de senaste 90 dagarna, dividerat med det totala antalet aktier och multiplicerat med 100.

Insiderhandelsdiagram

Medicines Company insideraffärer visas i följande diagram. Insiders är tjänstemän, styrelseledamöter eller betydande investerare i ett företag. I allmänhet är det i allmänhet olagligt för insiders att göra affärer i sina företag baserat på väsentlig, icke-offentlig information. Detta betyder inte att det är olagligt för dem att göra några affärer i sina egna företag. De måste dock rapportera alla affärer till SEC via ett formulär 4.

Insiderlista och lönsamhetsstatistik

Den här tabellen visar listan över kända insiders och genereras automatiskt från anmälningar som avslöjas till SEC. Förutom namnen, den senaste titeln och direktören, tjänstemannen eller ägarbeteckningen på 10 %, tillhandahåller vi de senaste avslöjade innehaven. Dessutom, när det är möjligt tillhandahåller vi insiderns historiska handelsresultat. Det historiska handelsresultatet är ett vägt genomsnitt av resultatet för faktiska köptransaktioner på den öppna marknaden som insidern gjort. För mer information om hur detta beräknas, titta på detta YouTube-webinarium.

See our leaderboard of most profitable insider traders.

Insider	Genomsnitt vinst (%)	Aktier Ägda	Delad Justerad

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Track Records av insiderköp - Kortsiktig vinstanalys

I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i MDCO / Medicines Company. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .

Tabellen nedan visar de senaste köpen på öppna marknaden som inte var en del av en automatisk handelsplan.

Handelsdatum	Insider	Rapporterade aktier	Rapporterat pris	Justerade aktier	Justerat pris	Kostnadsbasis	Dagar til Max
2019-06-28	DENNER ALEXANDER J	50 000	33,0000	50 000	33,0000	1 650 000	188
2019-05-30	DENNER ALEXANDER J	50 000	34,8100	50 000	34,8100	1 740 500
2019-05-29	DENNER ALEXANDER J	35 000	34,8500	35 000	34,8500	1 219 750
2019-05-22	DENNER ALEXANDER J	139 000	33,1300	139 000	33,1300	4 605 070
2019-05-21	DENNER ALEXANDER J	132 000	33,9500	132 000	33,9500	4 481 400
2019-05-20	DENNER ALEXANDER J	160 000	34,5000	160 000	34,5000	5 520 000
2019-03-06	DENNER ALEXANDER J	248 100	24,9100	248 100	24,9100	6 180 171
2019-03-05	DENNER ALEXANDER J	181 900	26,0700	181 900	26,0700	4 742 133
2019-03-04	DENNER ALEXANDER J	325 000	25,4500	325 000	25,4500	8 271 250

Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.

Track Records av insiderförsäljning - Kortsiktig förlustanalys

Tabellen nedan visar de senaste försäljningarna på öppna marknaden som inte var en del av en automatisk handelsplan.

Handelsdatum	Insider	Rapporterade aktier	Rapporterat pris	Justerade aktier	Justerat pris	Kostnadsbasis	Dagar til Min
2019-08-02	Rodin Stephen M	5 000	34,8200	5 000	34,8200	174 100	13
2018-08-01	MEANWELL CLIVE	50 000	39,2400	50 000	39,2400	1 962 000
2018-07-02	MEANWELL CLIVE	50 000	36,0700	50 000	36,0700	1 803 500
2018-05-25	Spigelman Melvin K	7 500	32,2000	7 500	32,2000	241 500
2018-03-21	CROUSE WILLIAM	7 500	32,2600	7 500	32,2600	241 950
2017-12-15	MEANWELL CLIVE	136 250	27,2400	136 250	27,2400	3 711 450
2016-11-15	MEANWELL CLIVE	20 000	40,0027	20 000	40,0027	800 054
2016-09-21	MEANWELL CLIVE	8 623	40,0000	8 623	40,0000	344 920
2016-09-01	MEANWELL CLIVE	1 377	40,0000	1 377	40,0000	55 080

Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.

Transaktionshistorik

Klicka på länkikonen för att se hela transaktionshistoriken. Transaktioner som rapporteras som en del av en automatisk handelsplan 10b5-1 kommer att ha ett X i kolumnen markerad 10b-5.

Fil datum	Handel datum	Schema	Insider	Ticker	Värdepappertitel	Kod	Direkta	Utövningspris	Enhet pris	Enheter ändrad	Värde ändrad (1K)	Kvarvarande Optioner	Kvarvarande Aktier
2020-01-06	2020-01-06	4	DENNER ALEXANDER J	MDCO	Stock Option	D - Sale to Issuer	D	34,81		−13 410		0
2020-01-06	2020-01-06	4	DENNER ALEXANDER J	MDCO	Stock Option	D - Sale to Issuer	D	33,86		−9 141		0
2020-01-06	2020-01-06	4	DENNER ALEXANDER J	MDCO	Stock Option	D - Sale to Issuer	D	39,39		−8 577		0
2020-01-06	2020-01-06	4	DENNER ALEXANDER J	MDCO	Stock Option	D - Sale to Issuer	D	37,22		−9 700		0
2020-01-06	2020-01-06	4	DENNER ALEXANDER J	MDCO	Stock Option	D - Sale to Issuer	D	32,86		−27 230		0
2020-01-06	2020-01-06	4	DENNER ALEXANDER J	MDCO	Common Stock	D - Sale to Issuer	I			−4 202 000			0
2020-01-06	2020-01-06	4	DENNER ALEXANDER J	MDCO	Common Stock	D - Sale to Issuer	D			−85 813			0
2020-01-06	2020-01-06	4	Germano Geno J By grantor retained annuity trust	MDCO	Stock Option	D - Sale to Issuer	I	34,81		−8 410		0
2020-01-06	2020-01-06	4	Germano Geno J By grantor retained annuity trust	MDCO	Stock Option	D - Sale to Issuer	I	33,86		−9 141		0
2020-01-06	2020-01-06	4	Germano Geno J By grantor retained annuity trust	MDCO	Stock Option	D - Sale to Issuer	I	30,90		−27 243		0
2020-01-06	2020-01-06	4	Germano Geno J	MDCO	Common Stock	D - Sale to Issuer	D			−7 429			0
2020-01-06	2020-01-06	4	Kelly John C. By trust	MDCO	Stock Option	D - Sale to Issuer	I	33,86		−9 141		0
2020-01-06	2020-01-06	4	Kelly John C.	MDCO	Stock Option	D - Sale to Issuer	D	34,81		−8 410		0
2020-01-06	2020-01-06	4	Kelly John C. By trust	MDCO	Stock Option	D - Sale to Issuer	I	39,39		−8 577		0
2020-01-06	2020-01-06	4	Kelly John C. By trust	MDCO	Stock Option	D - Sale to Issuer	I	28,14		−16 512		0
2020-01-06	2020-01-06	4	Kelly John C. By trust	MDCO	Stock Option	D - Sale to Issuer	I	37,22		−9 700		0
2020-01-06	2020-01-06	4	Kelly John C. By trust	MDCO	Stock Option	D - Sale to Issuer	I	27,78		−10 016		0
2020-01-06	2020-01-06	4	Kelly John C. By trust	MDCO	Stock Option	D - Sale to Issuer	I	33,13		−9 763		0
2020-01-06	2020-01-06	4	Kelly John C. By trust	MDCO	Stock Option	D - Sale to Issuer	I	21,14		−12 039		0
2020-01-06	2020-01-06	4	Kelly John C. By trust	MDCO	Stock Option	D - Sale to Issuer	I	18,18		−13 259		0
2020-01-06	2020-01-06	4	Kelly John C. By trust	MDCO	Stock Option	D - Sale to Issuer	I	16,00		−25 000		0
2020-01-06	2020-01-06	4	Kelly John C.	MDCO	Common Stock	D - Sale to Issuer	D			−32 148			0
2020-01-06	2019-09-26	4	Kelly John C. By trust	MDCO	Stock Option	G - Gift	I	33,86		9 141		9 141
2020-01-06	2019-09-26	4	Kelly John C.	MDCO	Stock Option	G - Gift	D	33,86		−9 141		0
2020-01-06	2019-09-26	4	Kelly John C. By trust	MDCO	Stock Option	G - Gift	I	39,39		8 577		8 577
2020-01-06	2019-09-26	4	Kelly John C.	MDCO	Stock Option	G - Gift	D	39,39		−8 577		0
2020-01-06	2019-09-26	4	Kelly John C. By trust	MDCO	Stock Option	G - Gift	I	37,22		9 700		9 700
2020-01-06	2019-09-26	4	Kelly John C.	MDCO	Stock Option	G - Gift	D	37,22		−9 700		0
2020-01-06	2019-09-26	4	Kelly John C. By trust	MDCO	Stock Option	G - Gift	I	28,14		16 512		16 512
2020-01-06	2019-09-26	4	Kelly John C.	MDCO	Stock Option	G - Gift	D	28,14		−16 512		0
2020-01-06	2019-09-26	4	Kelly John C. By trust	MDCO	Stock Option	G - Gift	I	27,78		10 016		10 016
2020-01-06	2019-09-26	4	Kelly John C.	MDCO	Stock Option	G - Gift	D	27,78		−10 016		0
2020-01-06	2019-09-26	4	Kelly John C. By trust	MDCO	Stock Option	G - Gift	I	33,13		9 763		9 763
2020-01-06	2019-09-26	4	Kelly John C.	MDCO	Stock Option	G - Gift	D	33,13		−9 763		0
2020-01-06	2019-09-26	4	Kelly John C. By trust	MDCO	Stock Option	G - Gift	I	21,14		12 039		12 039
2020-01-06	2019-09-26	4	Kelly John C.	MDCO	Stock Option	G - Gift	D	21,14		−12 039		0
2020-01-06	2019-09-26	4	Kelly John C. By trust	MDCO	Stock Option	G - Gift	I	18,18		13 259		13 259
2020-01-06	2019-09-26	4	Kelly John C.	MDCO	Stock Option	G - Gift	D	18,18		−13 259		0
2020-01-06	2019-09-26	4	Kelly John C. By trust	MDCO	Stock Option	G - Gift	I	16,00		25 000		25 000
2020-01-06	2019-09-26	4	Kelly John C.	MDCO	Stock Option	G - Gift	D	16,00		−25 000		0
2020-01-06	2020-01-06	4	MEANWELL CLIVE	MDCO	Stock Option	D - Sale to Issuer	D	25,41		−95 000		0
2020-01-06	2020-01-06	4	MEANWELL CLIVE	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−117 000		0
2020-01-06	2020-01-06	4	MEANWELL CLIVE	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−117 000		0
2020-01-06	2020-01-06	4	MEANWELL CLIVE	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−234 000		0
2020-01-06	2020-01-06	4	MEANWELL CLIVE	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−87 750		0
2020-01-06	2020-01-06	4	MEANWELL CLIVE	MDCO	Stock Option	D - Sale to Issuer	D	52,70		−210 793		0
2020-01-06	2020-01-06	4	MEANWELL CLIVE	MDCO	Stock Option	D - Sale to Issuer	D	33,04		−297 776		0
2020-01-06	2020-01-06	4	MEANWELL CLIVE	MDCO	Stock Option	D - Sale to Issuer	D	28,77		−234 375		0
2020-01-06	2020-01-06	4	MEANWELL CLIVE	MDCO	Stock Option	D - Sale to Issuer	D	30,55		−120 000		0
2020-01-06	2020-01-06	4	MEANWELL CLIVE	MDCO	Common Stock	D - Sale to Issuer	D			−480 340			0
2020-01-06	2020-01-06	4	Panayiotopoulos Paris	MDCO	Stock Option	D - Sale to Issuer	D	34,81		−8 410		0
2020-01-06	2020-01-06	4	Panayiotopoulos Paris	MDCO	Stock Option	D - Sale to Issuer	D	33,86		−9 141		0
2020-01-06	2020-01-06	4	Panayiotopoulos Paris	MDCO	Stock Option	D - Sale to Issuer	D	39,39		−8 577		0
2020-01-06	2020-01-06	4	Panayiotopoulos Paris	MDCO	Stock Option	D - Sale to Issuer	D	51,02		−16 559		0
2020-01-06	2020-01-06	4	Panayiotopoulos Paris	MDCO	Common Stock	D - Sale to Issuer	D			−13 881			0
2020-01-06	2020-01-06	4	Rodin Stephen M	MDCO	Stock Option	D - Sale to Issuer	D	25,41		−40 000		0
2020-01-06	2020-01-06	4	Rodin Stephen M	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−24 000		0
2020-01-06	2020-01-06	4	Rodin Stephen M	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−24 000		0
2020-01-06	2020-01-06	4	Rodin Stephen M	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−48 000		0
2020-01-06	2020-01-06	4	Rodin Stephen M	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−18 000		0
2020-01-06	2020-01-06	4	Rodin Stephen M	MDCO	Common Stock	D - Sale to Issuer	D			−84 782			0
2020-01-06	2020-01-06	4	Schlesinger Sarah J.	MDCO	Stock Option	D - Sale to Issuer	D	34,81		−8 410		0
2020-01-06	2020-01-06	4	Schlesinger Sarah J.	MDCO	Stock Option	D - Sale to Issuer	D	33,86		−9 141		0
2020-01-06	2020-01-06	4	Schlesinger Sarah J.	MDCO	Stock Option	D - Sale to Issuer	D	29,83		−26 383		0
2020-01-06	2020-01-06	4	Schlesinger Sarah J.	MDCO	Common Stock	D - Sale to Issuer	D			−7 429			0
2020-01-06	2020-01-06	4	Timney Mark	MDCO	Stock Option	D - Sale to Issuer	D	20,79		−110 000		0
2020-01-06	2020-01-06	4	Timney Mark	MDCO	Stock Option	D - Sale to Issuer	D	20,79		−110 000		0
2020-01-06	2020-01-06	4	Timney Mark	MDCO	Stock Option	D - Sale to Issuer	D	20,79		−220 000		0
2020-01-06	2020-01-06	4	Timney Mark	MDCO	Stock Option	D - Sale to Issuer	D	20,79		−82 500		0
2020-01-06	2020-01-06	4	Timney Mark	MDCO	Stock Option	D - Sale to Issuer	D	20,79		−45 000		0
2020-01-06	2020-01-06	4	Timney Mark	MDCO	Common Stock	D - Sale to Issuer	D			−185 415			0
2020-01-06	2020-01-06	4	Visioli Christopher	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−24 000		0
2020-01-06	2020-01-06	4	Visioli Christopher	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−30 000		0
2020-01-06	2020-01-06	4	Visioli Christopher	MDCO	Common Stock	D - Sale to Issuer	D			−68 843			0
2020-01-06	2020-01-06	4	Wijngaard Peter	MDCO	Stock Option	D - Sale to Issuer	D	29,01		−30 000		0
2020-01-06	2020-01-06	4	Wijngaard Peter	MDCO	Stock Option	D - Sale to Issuer	D	28,77		−30 000		0
2020-01-06	2020-01-06	4	Wijngaard Peter	MDCO	Stock Option	D - Sale to Issuer	D	33,04		−42 539		0
2020-01-06	2020-01-06	4	Wijngaard Peter	MDCO	Stock Option	D - Sale to Issuer	D	28,77		−7 143		0
2020-01-06	2020-01-06	4	Wijngaard Peter	MDCO	Stock Option	D - Sale to Issuer	D	30,55		−23 639		0
2020-01-06	2020-01-06	4	Wijngaard Peter	MDCO	Stock Option	D - Sale to Issuer	D	31,49		−40 995		0
2020-01-06	2020-01-06	4	Wijngaard Peter	MDCO	Stock Option	D - Sale to Issuer	D	22,04		−17 500		0
2020-01-06	2020-01-06	4	Wijngaard Peter	MDCO	Stock Option	D - Sale to Issuer	D	15,94		−10 000		0
2020-01-06	2020-01-06	4	Wijngaard Peter	MDCO	Common Stock	D - Sale to Issuer	D			−107 546			0
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Stock Option	M - Exercise	D	30,55		−11 483		120 000
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Stock Option	M - Exercise	D	31,49		−64 568		0
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Stock Option	M - Exercise	D	22,04		−150 000		0
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Stock Option	M - Exercise	D	17,45		−240 000		0
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Stock Option	M - Exercise	D	13,54		−15 620		0
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Stock Option	M - Exercise	D	7,31		−60 000		0
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		84,7800	−22 345	−1 894		480 340
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		84,7800	−329 796	−27 960		502 685
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		30,5500	11 483	351		832 481
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		31,4900	64 568	2 033		820 998
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		22,0400	150 000	3 306		756 430
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		17,4500	240 000	4 188		606 430
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		13,5400	15 620	211		366 430
2019-12-31	2019-12-27	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		7,3100	60 000	439		350 810
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	25,41		−25 000		40 000
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	52,70		−42 159		0
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	33,04		−47 644		0
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	28,77		−5 000		0
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	30,07		−40 000		0
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	30,55		−3 582		0
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	31,49		−2 196		0
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	22,04		−3 516		0
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	7,31		−7 500		0
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	17,45		−7 500		0
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Stock Option	M - Exercise	D	13,57		−10 000		0
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		84,7800	−4 887	−414		84 782
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		84,7800	−133 635	−11 330		89 669
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		25,4100	25 000	635		223 304
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		52,7000	42 159	2 222		198 304
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		33,0400	47 644	1 574		156 145
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		28,7700	5 000	144		108 501
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		30,0700	40 000	1 203		103 501
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		30,5500	3 582	109		63 501
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		31,4900	2 196	69		59 919
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		22,0400	3 516	77		57 723
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		17,4500	7 500	131		54 207
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		13,5700	10 000	136		46 707
2019-12-31	2019-12-27	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		7,3100	7 500	55		36 707
2019-12-31	2019-12-27	4	Timney Mark	MDCO	Stock Option	M - Exercise	D	20,79		−405 000		45 000
2019-12-31	2019-12-27	4	Timney Mark	MDCO	Common Stock	F - Taxes	D		84,7800	−249 865	−21 184		185 415
2019-12-31	2019-12-27	4	Timney Mark	MDCO	Common Stock	M - Exercise	D		84,7800	405 000	34 336		435 280
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	25,41		−65 000		0
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	29,01		−18 000		30 000
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	29,01		−18 000		30 000
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	29,01		−24 000		0
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	52,70		−15 810		0
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	33,04		−12 889		0
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	28,77		−16 500		0
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	28,77		−4 375		0
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	30,55		−3 477		0
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	31,49		−1 441		0
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	22,04		−6 635		0
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Stock Option	M - Exercise	D	17,45		−6 000		0
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	F - Taxes	D		84,7800	−2 066	−175		68 843
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	F - Taxes	D		84,7800	−128 470	−10 892		70 909
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		25,4100	65 000	1 652		199 379
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		29,0100	18 000	522		134 379
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		29,0100	18 000	522		134 379
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		29,0100	24 000	696		116 379
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		52,7000	15 810	833		74 379
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		33,0400	12 889	426		58 569
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		28,7700	16 500	475		45 680
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		28,7700	4 375	126		29 180
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		30,5500	3 477	106		24 805
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		31,4900	1 441	45		21 328
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		22,0400	6 635	146		19 887
2019-12-31	2019-12-27	4	Visioli Christopher	MDCO	Common Stock	M - Exercise	D		17,4500	6 000	105		13 252
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Stock Option	M - Exercise	D	25,41		−125 000		0
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Stock Option	M - Exercise	D	29,01		−5 000		30 000
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Stock Option	M - Exercise	D	29,01		−70 000		0
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Stock Option	M - Exercise	D	29,01		−35 000		0
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Stock Option	M - Exercise	D	29,01		−26 250		0
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Stock Option	M - Exercise	D	33,27		−18 000		0
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Stock Option	M - Exercise	D	52,70		−50 189		0
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Common Stock	F - Taxes	D		84,7800	−224 341	−19 020		107 546
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Common Stock	M - Exercise	D		25,4100	125 000	3 176		331 887
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Common Stock	M - Exercise	D		29,0100	5 000	145		206 887
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Common Stock	M - Exercise	D		29,0100	70 000	2 031		201 887
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Common Stock	M - Exercise	D		29,0100	35 000	1 015		131 887
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Common Stock	M - Exercise	D		29,0100	26 250	762		96 887
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Common Stock	M - Exercise	D		33,2700	18 000	599		70 637
2019-12-31	2019-12-27	4	Wijngaard Peter	MDCO	Common Stock	M - Exercise	D		52,7000	50 189	2 645		52 637
2019-09-04	2019-08-30	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		21,6000	491	11		290 810
2019-09-04	2019-08-30	4	Wijngaard Peter	MDCO	Common Stock	A - Award	D		21,6000	491	11		2 448
2019-09-04	2019-08-30	4	Timney Mark	MDCO	Common Stock	A - Award	D		21,6000	491	11		30 280
2019-09-04	2019-08-30	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D		21,6000	491	11		28 630
2019-08-06	2019-08-02	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D	8,38		−5 000		0
2019-08-06	2019-08-02	4	Rodin Stephen M	MDCO	Common Stock	S - Sale	D		34,8200	−5 000	−174		28 139
2019-08-06	2019-08-02	4	Rodin Stephen M	MDCO	Common Stock	M - Exercise	D		8,3800	5 000	42		33 139
2019-06-28	2019-06-28	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		33,0000	50 000	1 650		4 202 000
2019-06-10		3/A	Wijngaard Peter	MDCO	Common Stock		D						1 957
2019-06-03	2019-05-30	4	Kelly John C.	MDCO	Stock Option (right-to-buy)	A - Award	D	34,81		8 410		8 410
2019-06-03	2019-05-30	4	Kelly John C.	MDCO	Common Stock	A - Award	D			3 663			32 148
2019-06-03	2019-05-30	4	Germano Geno J	MDCO	Stock Options (right-to-buy)	A - Award	D	34,81		8 410		8 410
2019-06-03	2019-05-30	4	Germano Geno J	MDCO	Common Stock	A - Award	D			3 663			7 429
2019-06-03	2019-05-30	4	DENNER ALEXANDER J	MDCO	Stock Option (right-to-buy)	A - Award	D	34,81		13 410		13 410
2019-06-03	2019-05-30	4	DENNER ALEXANDER J	MDCO	Common Stock	A - Award	D			3 663			14 092
2019-06-03	2019-05-30	4	Schlesinger Sarah J.	MDCO	Stock Option (right-to-buy)	A - Award	D	34,81		8 410		8 410
2019-06-03	2019-05-30	4	Schlesinger Sarah J.	MDCO	Common Stock	A - Award	D			3 663			7 429
2019-06-03	2019-05-30	4	Panayiotopoulos Paris	MDCO	Stock Option (right-to-buy)	A - Award	D	34,81		8 410		8 410
2019-06-03	2019-05-30	4	Panayiotopoulos Paris	MDCO	Common Stock	A - Award	D			3 663			13 881
2019-05-31	2019-05-30	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		34,8100	50 000	1 740		4 152 000
2019-05-31	2019-05-29	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		34,8500	35 000	1 220		4 102 000
2019-05-22	2019-05-22	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		33,1300	139 000	4 605		4 067 000
2019-05-22	2019-05-21	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		33,9500	132 000	4 481		3 928 000
2019-05-22	2019-05-20	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		34,5000	160 000	5 520		3 796 000
2019-04-26	2019-04-25	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		30,4800	−2 796	−85		290 319
2019-03-08	2019-03-06	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		24,9100	248 100	6 180		3 636 000
2019-03-06	2019-03-04	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		25,5300	−2 962	−76		293 115
2019-03-06	2019-03-04	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		25,5300	−3 586	−92		296 077
2019-03-06	2019-03-04	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		25,5300	−3 063	−78		299 663
2019-03-06	2019-03-04	4	Visioli Christopher	MDCO	Common Stock	F - Taxes	D		25,5300	−381	−10		7 252
2019-03-06	2019-03-04	4	Visioli Christopher	MDCO	Common Stock	F - Taxes	D		25,5300	−238	−6		7 633
2019-03-06	2019-03-04	4	Visioli Christopher	MDCO	Common Stock	F - Taxes	D		25,5300	−212	−5		7 871
2019-03-06	2019-03-04	4	Visioli Christopher	MDCO	Common Stock	F - Taxes	D		25,5300	−78	−2		8 083
2019-03-06	2019-03-04	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		25,5300	−476	−12		28 139
2019-03-06	2019-03-04	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		25,5300	−527	−13		28 615
2019-03-06	2019-03-04	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		25,5300	−671	−17		29 142
2019-03-06	2019-03-04	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		25,5300	−78	−2		29 813
2019-03-06	2019-03-04	4	Cox Christopher T	MDCO	Common Stock	F - Taxes	D		25,5300	−1 436	−37		57 987
2019-03-06	2019-03-04	4	Cox Christopher T	MDCO	Common Stock	F - Taxes	D		25,5300	−1 202	−31		59 423
2019-03-05	2019-03-05	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		26,0700	181 900	4 742		3 387 900
2019-03-05	2019-03-04	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		25,4500	325 000	8 271		3 206 000
2019-03-05	2019-03-01	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		25,1500	100 000	2 515		2 881 000
2019-03-04	2019-03-01	4	Visioli Christopher	MDCO	Stock option (right-to-buy)	A - Award	D	25,41		65 000		65 000
2019-03-04	2019-03-01	4	MEANWELL CLIVE	MDCO	Stock option (right to buy)	A - Award	D	25,41		95 000		95 000
2019-03-04	2019-02-28	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		20,9700	317	7		302 726
2019-03-04	2019-03-01	4	Rodin Stephen M	MDCO	Stock option (right to buy)	A - Award	D	25,41		65 000		65 000
2019-03-04	2019-02-28	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D		20,9700	317	7		29 891
2019-03-04	2019-02-28	4	Cox Christopher T	MDCO	Common Stock	A - Award	D		20,9700	317	7		60 625
2018-12-27	2018-12-21	4	Timney Mark	MDCO	Common Stock	P - Purchase	D		17,9000	2 926	52		29 789
2018-12-21	2018-12-20	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		17,8900	10 000	179		2 781 000
2018-12-21	2018-12-20	4	Cox Christopher T	MDCO	Common Stock	P - Purchase	I		17,7000	113 500	2 009		334 955
2018-12-18	2018-12-17	4	Timney Mark	MDCO	Common Stock	P - Purchase	D		18,6000	26 863	500		26 863
2018-12-18	2018-12-10	4	Timney Mark	MDCO	Option (right to buy)	A - Award	D	20,79		450 000		450 000
2018-12-18	2018-12-18	4	DENNER ALEXANDER J	MDCO	3.50% Convertible Senior Notes due 2024	P - Purchase	I	25,19	20 000 000,0000
2018-12-18	2018-12-18	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		18,1800	10 000	182		2 771 000
2018-12-18	2018-12-17	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		17,9100	20 000	358		2 761 000
2018-12-17	2018-12-14	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		18,9700	219 000	4 154		2 741 000
2018-12-17	2018-12-13	4	DENNER ALEXANDER J	MDCO	Common Stock	P - Purchase	I		20,7300	600 000	12 438		2 522 000
2018-11-19	2018-11-16	4	Cox Christopher T	MDCO	Common Stock	P - Purchase	I		19,7300	50 300	992		221 455
2018-09-05	2018-08-31	4	Cox Christopher T	MDCO	Common Stock	A - Award	D		28,2800	375	11		60 308
2018-09-05	2018-09-04	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		39,3100	−50 000	−1 966		302 409
2018-09-05	2018-08-31	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		28,2800	375	11		352 409
2018-09-05	2018-08-31	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D		28,2800	375	11		29 574
2018-08-02	2018-08-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		39,2400	−50 000	−1 962		352 034
2018-07-05	2018-07-02	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		36,0700	−50 000	−1 804		402 034
2018-06-04	2018-05-31	4	Kelly John C.	MDCO	Stock Option (right-to-buy)	A - Award	D	33,86		9 141		9 141
2018-06-04	2018-05-31	4	Kelly John C.	MDCO	Common Stock	A - Award	D			3 766			28 485
2018-06-04	2018-05-31	4	Germano Geno J	MDCO	Stock Option (right-to-buy)	A - Award	D	33,86		9 141		9 141
2018-06-04	2018-05-31	4	Germano Geno J	MDCO	Common Stock	A - Award	D			3 766			3 766
2018-06-04	2018-05-31	4	Panayiotopoulos Paris	MDCO	Stock Option (right-to-buy)	A - Award	D	33,86		9 141		9 141
2018-06-04	2018-05-31	4	Panayiotopoulos Paris	MDCO	Common Stock	A - Award	D			3 766			10 218
2018-06-04	2018-05-31	4	Schlesinger Sarah J.	MDCO	Stock Option (right-to-buy)	A - Award	D	33,86		9 141		9 141
2018-06-04	2018-05-31	4	Schlesinger Sarah J.	MDCO	Common Stock	A - Award	D			3 766			3 766
2018-06-04	2018-05-31	4	ESHELMAN FREDRIC N	MDCO	Stock Option (right-to-buy)	A - Award	D	33,86		14 141		14 141
2018-06-04	2018-05-31	4	ESHELMAN FREDRIC N	MDCO	Common Stock	A - Award	D			3 766			1 132 149
2018-06-04	2018-05-31	4	DENNER ALEXANDER J	MDCO	Stock Option (right-to-buy)	A - Award	D	33,86		9 141		9 141
2018-06-04	2018-05-31	4	DENNER ALEXANDER J	MDCO	Common Stock	A - Award	D			3 766			10 429
2018-05-29	2018-05-25	4	Spigelman Melvin K	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,30		−7 500		0
2018-05-29	2018-05-25	4	Spigelman Melvin K	MDCO	Common Stock	S - Sale	D		32,2000	−7 500	−242		53 133
2018-05-29	2018-05-25	4	Spigelman Melvin K	MDCO	Common Stock	M - Exercise	D		18,3000	7 500	137		60 633
2018-05-14	2018-05-10	4	KESSLER ARMIN M	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,30		−7 500		0
2018-05-14	2018-05-10	4	KESSLER ARMIN M	MDCO	Common Stock	M - Exercise	D		18,3000	7 500	137		138 493
2018-04-26	2018-04-24	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D			22 589			452 034
2018-04-18	2018-04-16	4	KESSLER ARMIN M	MDCO	Common Stock	S - Sale	D		30,0500	−10 000	−300		130 993
2018-04-18	2018-01-16	4	KESSLER ARMIN M	MDCO	Common Stock	S - Sale	D		27,3700	−10 000	−274		140 993
2018-04-02		3	Visioli Christopher	MDCO	Common Stock		D						16 322
2018-04-02		3	Visioli Christopher	MDCO	Common Stock		D						16 322
2018-04-02		3	Visioli Christopher	MDCO	Common Stock		D						16 322
2018-03-23	2018-03-21	4	CROUSE WILLIAM	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,30		−7 500		0
2018-03-23	2018-03-21	4	CROUSE WILLIAM	MDCO	Common Stock	S - Sale	D		32,2600	−7 500	−242		53 133
2018-03-23	2018-03-21	4	CROUSE WILLIAM	MDCO	Common Stock	M - Exercise	D		18,3000	7 500	137		60 633
2018-03-23	2018-03-22	4	WYATT ELIZABETH H S	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,30		−7 500		0
2018-03-23	2018-03-22	4	WYATT ELIZABETH H S	MDCO	Common Stock	M - Exercise	D		18,3000	7 500	137		60 633
2018-03-05	2018-03-02	4	Cox Christopher T	MDCO	Common Stock	F - Taxes	D		33,2900	−1 010	−34		59 933
2018-03-05	2018-03-02	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		33,2900	−1 312	−44		29 199
2018-03-05	2018-03-02	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		33,2900	−2 663	−89		21 882
2018-03-05	2018-03-02	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		33,2900	−22 287	−742		429 445
2018-03-05	2018-03-02	4	Frazier Jeff	MDCO	Common Stock	F - Taxes	D		33,2900	−1 426	−47		34 350
2018-03-02	2018-03-01	4	Cox Christopher T	MDCO	Common Stock	A - Award	D			15 000			60 943
2018-03-02	2018-02-28	4	Cox Christopher T	MDCO	Common Stock	A - Award	D		26,0200	330	9		45 943
2018-03-02	2018-02-28	4	Frazier Jeff	MDCO	Common Stock	A - Award	D		26,0200	330	9		35 776
2018-03-02	2018-02-28	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		26,0200	330	9		451 732
2018-03-02	2018-02-28	4	O'Connor William Bernard	MDCO	Common Stock	A - Award	D		26,0200	330	9		24 545
2018-03-02	2018-03-01	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D			6 250			30 511
2018-03-02	2018-02-28	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D		26,0200	330	9		24 261
2018-02-26	2018-02-22	4	Schlesinger Sarah J.	MDCO	Call Option (right-to-buy)	A - Award	D	29,83		26 383		26 383
2017-12-19	2017-12-15	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,36		−200 920		0
2017-12-19	2017-12-15	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		27,2400	−136 250	−3 711		451 402
2017-12-19	2017-12-15	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		19,3600	200 920	3 890		587 652
2017-12-11	2017-12-08	4	ESHELMAN FREDRIC N	MDCO	Common Stock	P - Purchase	D		26,6500	100 000	2 665		1 128 383
2017-12-11	2017-12-07	4	ESHELMAN FREDRIC N	MDCO	Common Stock	P - Purchase	D		26,4600	100 000	2 646		1 028 383
2017-12-01	2017-11-30	4	Panayiotopoulos Paris	MDCO	Common Stock	P - Purchase	D		30,9700	3 215	100		6 452
2017-11-30	2017-11-29	4	DENNER ALEXANDER J See Footnotes	MDCO	Common Stock	P - Purchase	I		30,0300	170 000	5 105		1 922 000
2017-11-20	2017-11-09	4	Germano Geno J	MDCO	Call Option (right-to-buy)	A - Award	D	30,90		27 243		27 243
2017-11-13	2017-11-09	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	M - Exercise	D	21,14		−12 039		0
2017-11-13	2017-11-09	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,18		−13 259		0
2017-11-13	2017-11-09	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,30		−7 500		0
2017-11-13	2017-11-09	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	M - Exercise	D	8,28		−7 500		0
2017-11-13	2017-11-09	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	M - Exercise	D	7,51		−7 500		0
2017-11-13	2017-11-09	4	HUGIN ROBERT J	MDCO	Common Stock	M - Exercise	D		21,1400	12 039	255		163 431
2017-11-13	2017-11-09	4	HUGIN ROBERT J	MDCO	Common Stock	M - Exercise	D		18,1800	13 259	241		151 392
2017-11-13	2017-11-09	4	HUGIN ROBERT J	MDCO	Common Stock	M - Exercise	D		8,2800	7 500	62		138 133
2017-11-13	2017-11-09	4	HUGIN ROBERT J	MDCO	Common Stock	M - Exercise	D		7,5100	7 500	56		130 633
2017-11-13	2017-11-09	4	HUGIN ROBERT J	MDCO	Common Stock	M - Exercise	D		18,3000	7 500	137		123 133
2017-09-05	2017-08-31	4	Frazier Jeff	MDCO	Common Stock	A - Award	D		31,1800	237	7		35 446
2017-09-05	2017-08-31	4	Cox Christopher T	MDCO	Common Stock	A - Award	D		31,1800	237	7		45 613
2017-09-05	2017-08-31	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D		31,1800	237	7		23 931
2017-09-05	2017-08-31	4	O'Connor William Bernard	MDCO	Common Stock	A - Award	D		31,1800	237	7		24 215
2017-09-05	2017-08-31	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		31,1800	237	7		386 732
2017-08-31	2017-08-31	4	DENNER ALEXANDER J See Footnotes	MDCO	Common Stock	A - Award	I		36,6900	7 146	262		1 752 000
2017-06-07	2017-06-05	4	Frazier Jeff	MDCO	Common Stock	F - Taxes	D		40,0000	−2 168	−87		35 209
2017-05-30	2017-05-25	4	Shigeta Hiroaki	MDCO	Stock Option (right-to-buy)	A - Award	D	39,39		8 577		8 577
2017-05-30	2017-05-25	4	Shigeta Hiroaki	MDCO	Common Stock	A - Award	D			3 237			26 784
2017-05-30	2017-05-25	4	DENNER ALEXANDER J	MDCO	Stock Option (right-to-buy	A - Award	D	39,39		8 577		8 577
2017-05-30	2017-05-25	4	DENNER ALEXANDER J	MDCO	Common Stock	A - Award	D			3 237			6 663
2017-05-30	2017-05-25	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	A - Award	D	39,39		8 577		8 577
2017-05-30	2017-05-25	4	HUGIN ROBERT J	MDCO	Common Stock	A - Award	D			3 237			115 633
2017-05-30	2017-05-25	4	Kelly John C.	MDCO	Stock Option (right-to-buy)	A - Award	D	39,39		8 577		8 577
2017-05-30	2017-05-25	4	Kelly John C.	MDCO	Common Stock	A - Award	D			3 237			24 719
2017-05-30	2017-05-25	4	KESSLER ARMIN M	MDCO	Stock Option (right-to-buy)	A - Award	D	39,39		8 577		8 577
2017-05-30	2017-05-25	4	KESSLER ARMIN M	MDCO	Common Stock	A - Award	D			3 237			150 993
2017-05-30	2017-05-25	4	CROUSE WILLIAM	MDCO	Stock Option (right-to-buy)	A - Award	D	39,39		8 577		8 577
2017-05-30	2017-05-25	4	CROUSE WILLIAM	MDCO	Common Stock	A - Award	D			3 237			53 133
2017-05-30	2017-05-25	4	ESHELMAN FREDRIC N	MDCO	Stock Option (right-to-buy)	A - Award	D	39,39		13 577		13 577
2017-05-30	2017-05-25	4	ESHELMAN FREDRIC N	MDCO	Common Stock	A - Award	D			3 237			928 383
2017-05-30	2017-05-25	4	WYATT ELIZABETH H S	MDCO	Stock Option (right-to-buy)	A - Award	D	39,39		8 577		8 577
2017-05-30	2017-05-25	4	WYATT ELIZABETH H S	MDCO	Common Stock	A - Award	D			3 237			53 133
2017-05-30	2017-05-25	4	Spigelman Melvin K	MDCO	Stock Option (right-to-buy	A - Award	D	39,39		8 577		8 577
2017-05-30	2017-05-25	4	Spigelman Melvin K	MDCO	Common Stock	A - Award	D			3 237			53 133
2017-05-30	2017-05-25	4	Panayiotopoulos Paris	MDCO	Stock Option (right-to-buy)	A - Award	D	39,39		8 577		8 577
2017-05-30	2017-05-25	4	Panayiotopoulos Paris	MDCO	Common Stock	A - Award	D			3 237			3 237
2017-05-25	2017-05-23	4	Spigelman Melvin K	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,60		−7 500		0
2017-05-25	2017-05-23	4	Spigelman Melvin K	MDCO	Common Stock	M - Exercise	D		19,6000	7 500	147		49 896
2017-05-16	2017-05-12	4	CROUSE WILLIAM	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,60		−7 500		0
2017-05-16	2017-05-12	4	CROUSE WILLIAM	MDCO	Common Stock	M - Exercise	D		19,6000	7 500	147		49 896
2017-05-16	2017-05-16	4	WYATT ELIZABETH H S	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,60		−7 500		0
2017-05-16	2017-05-16	4	WYATT ELIZABETH H S	MDCO	Common Stock	M - Exercise	D		19,6000	7 500	147		49 896
2017-03-31	2017-03-28	4	Panayiotopoulos Paris	MDCO	Call Option (right-to-buy)	A - Award	D	51,02		16 559		16 559
2017-03-15	2017-03-13	4	KESSLER ARMIN M	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,60		−7 500		0
2017-03-15	2017-03-13	4	KESSLER ARMIN M	MDCO	Common Stock	M - Exercise	D		19,6000	7 500	147		147 756
2017-03-10	2017-03-08	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,60		−7 500		0
2017-03-10	2017-03-08	4	HUGIN ROBERT J	MDCO	Common Stock	M - Exercise	D		19,6000	7 500	147		112 396
2017-03-02	2017-03-01	4	Cox Christopher T	MDCO	Stock Option (right-to-buy)	A - Award	D	52,70		70 265		70 265
2017-03-02	2017-03-01	4	Cox Christopher T	MDCO	Common Stock	A - Award	D			11 386			45 376
2017-03-02	2017-02-28	4	Cox Christopher T	MDCO	Common Stock	A - Award	D		33,1200	320	11		33 990
2017-03-02	2017-03-02	4	Frazier Jeff	MDCO	Common Stock	F - Taxes	D		52,4000	−1 045	−55		37 377
2017-03-02	2017-03-01	4	Frazier Jeff	MDCO	Stock Option (right-to-buy)	A - Award	D	52,70		35 133		35 133
2017-03-02	2017-03-01	4	Frazier Jeff	MDCO	Common Stock	A - Award	D			5 693			38 422
2017-03-02	2017-02-28	4	Frazier Jeff	MDCO	Common Stock	A - Award	D		33,1200	320	11		32 729
2017-03-02	2017-03-02	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		52,4000	−27 149	−1 423		386 495
2017-03-02	2017-03-01	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	A - Award	D	52,70		210 793		210 793
2017-03-02	2017-03-01	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D			34 156			413 644
2017-03-02	2017-02-28	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		33,1200	320	11		379 488
2017-03-02	2017-03-01	4	Kingsley Stuart A	MDCO	Stock Option (right-to-buy)	A - Award	D	52,70		70 265		70 265
2017-03-02	2017-03-01	4	Kingsley Stuart A	MDCO	Common Stock	A - Award	D			11 386			11 386
2017-03-02	2017-03-02	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		52,4000	−4 414	−231		23 978
2017-03-02	2017-03-01	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	A - Award	D	52,70		49 185		49 185
2017-03-02	2017-03-01	4	O'Connor William Bernard	MDCO	Common Stock	A - Award	D			7 970			28 392
2017-03-02	2017-02-28	4	O'Connor William Bernard	MDCO	Common Stock	A - Award	D		33,1200	320	11		20 422
2017-03-02	2017-03-02	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		52,4000	−1 038	−54		23 694
2017-03-02	2017-03-01	4	Rodin Stephen M	MDCO	Stock Option (right-to-buy)	A - Award	D	52,70		42 159		42 159
2017-03-02	2017-03-01	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D			6 832			24 732
2017-03-02	2017-02-28	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D		33,1200	320	11		17 900
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	30,55		−16 282		6 705
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	31,49		−10 313		448
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,36		−15 907		0
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,06		−15 000		0
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		50,0000	−16 282	−814		20 102
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		30,5500	16 282	497		36 384
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		50,0000	−10 313	−516		20 102
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		31,4900	10 313	325		30 415
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		50,0000	−15 907	−795		20 102
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		19,3600	15 907	308		36 009
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		50,0000	−15 000	−750		20 102
2017-02-14	2017-02-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		19,0600	15 000	286		35 102
2017-02-07	2017-02-07	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,60		−15 000		0
2017-02-07	2017-02-07	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		47,4500	−2 900	−138		20 102
2017-02-07	2017-02-07	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		46,9800	−12 100	−568		23 002
2017-02-07	2017-02-07	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		28,6000	15 000	429		35 102
2017-02-07	2017-02-03	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	22,04		−10 833		0
2017-02-07	2017-02-03	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		45,0000	−10 833	−487		20 102
2017-02-07	2017-02-03	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		22,0400	10 833	239		30 935
2016-12-09	2016-12-07	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,60		−40 000		0
2016-12-09	2016-12-07	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,6000	40 000	1 144		379 168
2016-12-09	2016-12-08	4	Cox Christopher T	MDCO	Common Stock	P - Purchase	I		32,5200	16 500	537		171 155
2016-12-09	2016-12-07	4	Cox Christopher T	MDCO	Common Stock	P - Purchase	I		33,3300	89 000	2 966		154 655
2016-12-08	2016-12-08	4	ESHELMAN FREDRIC N	MDCO	Common Stock	P - Purchase	D		33,1900	5 501	183		925 146
2016-12-08	2016-12-08	4	ESHELMAN FREDRIC N	MDCO	Common Stock	P - Purchase	D		32,5100	19 188	624		919 645
2016-12-08	2016-12-07	4	ESHELMAN FREDRIC N	MDCO	Common Stock	P - Purchase	D		32,9000	86 587	2 849		900 457
2016-12-08	2016-12-07	4	ESHELMAN FREDRIC N	MDCO	Common Stock	P - Purchase	D		33,6100	172 764	5 807		813 870
2016-12-08	2016-12-06	4	ESHELMAN FREDRIC N	MDCO	Common Stock	P - Purchase	D		34,1500	337 680	11 532		641 106
2016-11-17	2016-11-15	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,60		−20 000		40 000
2016-11-17	2016-11-15	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		40,0027	−20 000	−800		339 168
2016-11-17	2016-11-15	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,6000	20 000	572		359 168
2016-09-23	2016-09-21	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,60		−8 623		60 000
2016-09-23	2016-09-21	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		40,0000	−8 623	−345		339 168
2016-09-23	2016-09-21	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,6000	8 623	247		347 791
2016-09-02	2016-09-01	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,60		−1 377		68 623
2016-09-02	2016-09-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		40,0000	−1 377	−55		339 168
2016-09-02	2016-09-01	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,6000	1 377	39		340 545
2016-09-02	2016-08-31	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		28,0800	378	11		339 168
2016-09-02	2016-08-31	4	O'Connor William Bernard	MDCO	Common Stock	A - Award	D		28,0800	378	11		20 102
2016-09-02	2016-08-31	4	Frazier Jeff	MDCO	Common Stock	A - Award	D		28,0800	378	11		32 409
2016-09-02	2016-08-31	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D		28,0800	378	11		17 580
2016-08-25	2016-08-24	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,60		−20 000		70 000
2016-08-25	2016-08-24	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		40,0000	−20 000	−800		338 790
2016-08-25	2016-08-24	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,6000	20 000	572		358 790
2016-07-13	2016-06-13	4/A	Shigeta Hiroaki	MDCO	Stock Option (right-to-buy)	M - Exercise	D	26,20		−20 000		0
2016-07-13	2016-06-13	4/A	Shigeta Hiroaki	MDCO	Common Stock	S - Sale	D		36,7600	−20 000	−735		27 396
2016-07-13	2016-06-13	4/A	Shigeta Hiroaki	MDCO	Common Stock	M - Exercise	D		26,2000	20 000	524		47 396
2016-07-13	2016-07-11	4	Shigeta Hiroaki	MDCO	Common Stock	S - Sale	D		38,5000	−3 849	−148		23 547
2016-06-20	2016-06-13	4	Shigeta Hiroaki	MDCO	Stock Option (right-to-buy)	M - Exercise	D	26,20		−20 000		0
2016-06-20	2016-06-13	4	Shigeta Hiroaki	MDCO	Common Stock	S - Sale	D		36,7600	−20 000	−735		27 396
2016-06-20	2016-06-13	4	Shigeta Hiroaki	MDCO	Common Stock	M - Exercise	D		26,2000	20 000	524		47 396
2016-06-10	2016-06-10	4	Cox Christopher T	MDCO	Common Stock	P - Purchase	D		37,2100	6 670	248		33 670
2016-06-10	2016-06-10	4	Cox Christopher T	MDCO	Common Stock	P - Purchase	I		37,2200	13 340	497		65 655
2016-06-10	2016-06-08	4	Cox Christopher T	MDCO	Common Stock	P - Purchase	I		38,4300	25 975	998		52 315
2016-06-08	2016-06-07	4	Cox Christopher T	MDCO	Common Stock	P - Purchase	I		37,9600	26 340	1 000		26 340
2016-06-08	2016-06-07	4	Cox Christopher T	MDCO	Common Stock	P - Purchase	D		37,4900	6 200	232		27 000
2016-06-08	2016-06-07	4	Cox Christopher T	MDCO	Common Stock	P - Purchase	D		37,0500	20 800	771		20 800
2016-06-03	2016-06-03	4	Frazier Jeff	MDCO	Common Stock	F - Taxes	D		37,5300	−1 969	−74		32 031
2016-05-31	2016-05-26	4	CROUSE WILLIAM	MDCO	Stock Option (right-to-buy)	A - Award	D	37,22		9 700		9 700
2016-05-31	2016-05-26	4	CROUSE WILLIAM	MDCO	Common Stock	A - Award	D			3 426			42 396
2016-05-31	2016-05-26	4	ESHELMAN FREDRIC N	MDCO	Stock Option (right-to-buy)	A - Award	D	37,22		14 700		14 700
2016-05-31	2016-05-26	4	ESHELMAN FREDRIC N	MDCO	Common Stock	A - Award	D			3 426			303 426
2016-05-31	2016-05-26	4	WYATT ELIZABETH H S	MDCO	Stock Option (right-to-buy)	A - Award	D	37,22		9 700		9 700
2016-05-31	2016-05-26	4	WYATT ELIZABETH H S	MDCO	Common Stock	A - Award	D			3 426			42 396
2016-05-31	2016-05-26	4	KESSLER ARMIN M	MDCO	Stock Option (right-to-buy)	A - Award	D	37,22		9 700		9 700
2016-05-31	2016-05-26	4	KESSLER ARMIN M	MDCO	Common Stock	A - Award	D			3 426			140 256
2016-05-31	2016-05-26	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	A - Award	D	37,22		9 700		9 700
2016-05-31	2016-05-26	4	HUGIN ROBERT J	MDCO	Common Stock	A - Award	D			3 426			104 896
2016-05-31	2016-05-26	4	Savage Robert G.	MDCO	Stock Option (right-to-buy)	A - Award	D	37,22		9 700		9 700
2016-05-31	2016-05-26	4	Savage Robert G.	MDCO	Common Stock	A - Award	D			3 426			31 146
2016-05-31	2016-05-26	4	Spigelman Melvin K	MDCO	Stock Option (right-to-buy)	A - Award	D	37,22		9 700		9 700
2016-05-31	2016-05-26	4	Spigelman Melvin K	MDCO	Common Stock	A - Award	D			3 426			42 396
2016-05-31	2016-05-26	4	DENNER ALEXANDER J	MDCO	Stock Option (right-to-buy)	A - Award	D	37,22		9 700		9 700
2016-05-31	2016-05-26	4	DENNER ALEXANDER J	MDCO	Common Stock	A - Award	D			3 426			3 426
2016-05-31	2016-05-26	4	Shigeta Hiroaki	MDCO	Stock Option (right-to-buy)	A - Award	D	37,22		9 700		9 700
2016-05-31	2016-05-26	4	Shigeta Hiroaki	MDCO	Common Stock	A - Award	D			3 426			27 396
2016-05-31	2016-05-26	4	Kelly John C.	MDCO	Stock Option (right-to-buy)	A - Award	D	37,22		9 700		9 700
2016-05-31	2016-05-26	4	Kelly John C.	MDCO	Common Stock	A - Award	D			3 426			21 482
2016-05-26	2016-05-24	4	Savage Robert G.	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,60		−10 000		0
2016-05-26	2016-05-24	4	Savage Robert G.	MDCO	Common Stock	S - Sale	D		36,9500	−10 000	−370		27 720
2016-05-26	2016-05-24	4	Savage Robert G.	MDCO	Common Stock	M - Exercise	D		18,6000	10 000	186		37 720
2016-05-26	2016-05-24	4	Spigelman Melvin K	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,60		−15 000		0
2016-05-26	2016-05-24	4	Spigelman Melvin K	MDCO	Common Stock	S - Sale	D		37,0000	−15 000	−555		38 970
2016-05-26	2016-05-24	4	Spigelman Melvin K	MDCO	Common Stock	M - Exercise	D		18,6000	15 000	279		53 970
2016-05-18	2016-05-16	4	CROUSE WILLIAM	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,60		−15 000		0
2016-05-18	2016-05-16	4	CROUSE WILLIAM	MDCO	Common Stock	S - Sale	D		35,1530	−15 000	−527		38 970
2016-05-18	2016-05-16	4	CROUSE WILLIAM	MDCO	Common Stock	M - Exercise	D		18,6000	15 000	279		53 970
2016-05-18	2016-05-16	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,60		−10 000		90 000
2016-05-18	2016-05-16	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		35,0000	−10 000	−350		338 790
2016-05-18	2016-05-16	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,6000	10 000	286		348 790
2016-05-18	2016-05-16	4	Kingsley Stuart A	MDCO	Call Option (right-to-buy)	A - Award	D	35,65		398 232		398 232
2016-05-13	2016-05-12	4	ESHELMAN FREDRIC N	MDCO	Common Stock	P - Purchase	D		33,6800	300 000	10 104		300 000
2016-05-13	2016-05-13	4	WYATT ELIZABETH H S	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,60		−4 153		0
2016-05-13	2016-05-13	4	WYATT ELIZABETH H S	MDCO	Common Stock	S - Sale	D		34,0000	−4 153	−141		38 970
2016-05-13	2016-05-13	4	WYATT ELIZABETH H S	MDCO	Common Stock	M - Exercise	D		18,6000	4 153	77		43 123
2016-05-13	2016-05-11	4	WYATT ELIZABETH H S	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,60		−10 847		4 153
2016-05-13	2016-05-11	4	WYATT ELIZABETH H S	MDCO	Common Stock	S - Sale	D		34,0920	−10 847	−370		38 970
2016-05-13	2016-05-11	4	WYATT ELIZABETH H S	MDCO	Common Stock	M - Exercise	D		18,6000	10 847	202		49 817
2016-03-08	2016-03-07	4	KESSLER ARMIN M	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,60		−15 000		0
2016-03-08	2016-03-07	4	KESSLER ARMIN M	MDCO	Common Stock	S - Sale	D		34,8200	−8 100	−282		136 830
2016-03-08	2016-03-07	4	KESSLER ARMIN M	MDCO	Common Stock	M - Exercise	D		18,6000	15 000	279		144 930
2016-03-08	2016-03-04	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		34,0100	−5 287	−180		19 724
2016-03-08	2016-03-04	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		35,0000	−3 330	−117		25 011
2016-03-02	2016-03-02	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		33,8500	−21 600	−731		338 790
2016-03-02	2016-03-01	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	A - Award	D	33,04		297 776		297 776
2016-03-02	2016-03-01	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D			45 400			360 390
2016-03-02	2016-02-29	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		27,3400	305	8		314 990
2016-03-02	2016-03-02	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		33,8500	−2 487	−84		28 341
2016-03-02	2016-03-01	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	A - Award	D	33,04		47 644		47 644
2016-03-02	2016-03-01	4	O'Connor William Bernard	MDCO	Common Stock	A - Award	D			7 264			30 828
2016-03-02	2016-03-02	4	Frazier Jeff	MDCO	Common Stock	F - Taxes	D		33,8500	−422	−14		34 000
2016-03-02	2016-03-01	4	Frazier Jeff	MDCO	Stock Option (right-to-buy)	A - Award	D	33,04		47 644		47 644
2016-03-02	2016-03-01	4	Frazier Jeff	MDCO	Common Stock	A - Award	D			7 264			34 422
2016-03-02	2016-02-29	4	Frazier Jeff	MDCO	Common Stock	A - Award	D		27,3400	305	8		27 158
2016-03-02	2016-03-02	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		33,8500	−395	−13		17 202
2016-03-02	2016-03-01	4	Rodin Stephen M	MDCO	Stock Option (right-to-buy)	A - Award	D	33,04		47 644		47 644
2016-03-02	2016-03-01	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D			7 264			17 597
2016-03-02	2016-02-29	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D		27,3400	305	8		10 333
2016-02-29	2016-02-25	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		32,4200	−10 220	−331		314 685
2016-02-29	2016-02-25	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		32,4200	−1 168	−38		23 564
2016-02-29	2016-02-25	4	Cox Christopher T	MDCO	Call Option (right-to-buy)	A - Award	D	32,49		302 205		302 205
2016-02-29	2016-02-25	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		32,4200	−208	−7		10 028
2016-02-19	2016-02-17	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,60		−15 000		0
2016-02-19	2016-02-17	4	HUGIN ROBERT J	MDCO	Common Stock	M - Exercise	D		18,6000	15 000	279		101 470
2016-02-04		3	DENNER ALEXANDER J Sarissa Capital Offshore Master Fund LP	MDCO	Common Stock		I						2 410 595
2016-02-04		3	DENNER ALEXANDER J Sarissa Capital Domestic Fund LP	MDCO	Common Stock		I						2 845 405
2016-02-04		3	DENNER ALEXANDER J Sarissa Capital Offshore Master Fund LP	MDCO	Common Stock		I						2 410 595
2016-02-04		3	DENNER ALEXANDER J Sarissa Capital Domestic Fund LP	MDCO	Common Stock		I						2 845 405
2016-02-04	2016-02-02	4	DENNER ALEXANDER J	MDCO	Call Option (right-to-buy)	A - Award	D	32,86		27 230		27 230
2015-11-25	2015-11-23	4	ESHELMAN FREDRIC N	MDCO	Call Option (right-to-buy)	P - Purchase	D	42,00	538,9000	1 000	539	1 000
2015-11-16	2015-11-13	4	Savage Robert G.	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,60		−5 000		10 000
2015-11-16	2015-11-13	4	Savage Robert G.	MDCO	Common Stock	S - Sale	D		39,3400	−5 000	−197		27 720
2015-11-16	2015-11-13	4	Savage Robert G.	MDCO	Common Stock	M - Exercise	D		18,6000	5 000	93		32 720
2015-09-04	2015-09-03	4	SBLENDORIO GLENN	MDCO	Stock Option (right-to-buy)	M - Exercise	D	22,04		−25 000		43 000
2015-09-04	2015-09-03	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		42,0000	−25 000	−1 050		99 805
2015-09-04	2015-09-03	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		22,0400	25 000	551		124 805
2015-09-02	2015-08-31	4	SBLENDORIO GLENN	MDCO	Stock Option (right-to-buy)	M - Exercise	D	17,45		−50 000		15 000
2015-09-02	2015-08-31	4	SBLENDORIO GLENN	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,36		−24 495		0
2015-09-02	2015-08-31	4	SBLENDORIO GLENN	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,60		−40 000		0
2015-09-02	2015-08-31	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		39,7537	−114 495	−4 552		99 805
2015-09-02	2015-08-31	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		17,4500	50 000	872		214 300
2015-09-02	2015-08-31	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		19,3600	24 495	474		164 300
2015-09-02	2015-08-31	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		28,6000	40 000	1 144		139 805
2015-09-02	2015-08-31	4	SBLENDORIO GLENN	MDCO	Common Stock	A - Award	D		24,7400	266	7		99 805
2015-09-02	2015-08-31	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,27		−49 998		0
2015-09-02	2015-08-31	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		39,3590	−49 998	−1 968		324 905
2015-09-02	2015-08-31	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		18,2700	49 998	913		374 903
2015-09-02	2015-08-31	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		24,7400	429	11		324 905
2015-09-02	2015-08-31	4	Spigelman Melvin K	MDCO	Stock Option (right-to-buy)	M - Exercise	D	20,87		−20 000		0
2015-09-02	2015-08-31	4	Spigelman Melvin K	MDCO	Common Stock	S - Sale	D		40,5000	−20 000	−810		38 970
2015-09-02	2015-08-31	4	Spigelman Melvin K	MDCO	Common Stock	M - Exercise	D		20,8700	20 000	417		58 970
2015-09-02	2015-08-31	4	Frazier Jeff	MDCO	Common Stock	A - Award	D		24,7400	429	11		26 853
2015-09-02	2015-08-31	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D		24,7400	429	11		10 236
2015-09-02	2015-08-31	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	17,45		−9 722		0
2015-09-02	2015-08-31	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	7,31		−729		0
2015-09-02	2015-08-31	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,98		−25 000		0
2015-09-02	2015-08-31	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		40,0000	−35 451	−1 418		24 732
2015-09-02	2015-08-31	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		17,4500	9 722	170		60 183
2015-09-02	2015-08-31	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		7,3100	729	5		50 461
2015-09-02	2015-08-31	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		19,9800	25 000	500		49 732
2015-09-01		3	ESHELMAN FREDRIC N Footnote	MDCO	Common Stock		I						1 889 074
2015-09-01		3	ESHELMAN FREDRIC N Footnote	MDCO	Common Stock		I						1 889 074
2015-09-01	2015-08-28	4	ESHELMAN FREDRIC N	MDCO	Stock Option (right-to-buy)	A - Award	D	33,64		24 080		24 080
2015-08-04	2015-08-03	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,27		−16 667		49 998
2015-08-04	2015-08-03	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		30,9570	−16 667	−516		324 476
2015-08-04	2015-08-03	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		18,2700	16 667	305		341 143
2015-07-02	2015-07-01	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,27		−16 667		66 665
2015-07-02	2015-07-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		28,3940	−16 667	−473		324 476
2015-07-02	2015-07-01	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		18,2700	16 667	305		341 143
2015-06-26	2015-06-25	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		32,0000	−3 305	−106		99 539
2015-06-10	2015-06-08	4	Shigeta Hiroaki	MDCO	Common Stock	S - Sale	D		28,9900	−7 500	−217		23 970
2015-06-05	2015-06-03	4	Frazier Jeff	MDCO	Common Stock	F - Taxes	D		28,6800	−2 169	−62		26 424
2015-06-03	2015-06-01	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,27		−16 667		83 332
2015-06-03	2015-06-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		28,1059	−16 667	−468		324 476
2015-06-03	2015-06-01	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		18,2700	16 667	305		341 143
2015-06-01	2015-05-28	4	CROUSE WILLIAM	MDCO	Stock Option (right-to-buy)	A - Award	D	28,14		11 512		11 512
2015-06-01	2015-05-28	4	CROUSE WILLIAM	MDCO	Common Stock	A - Award	D			4 531			38 970
2015-06-01	2015-05-28	4	WYATT ELIZABETH H S	MDCO	Stock Option (right-to-buy)	A - Award	D	28,14		11 512		11 512
2015-06-01	2015-05-25	4	WYATT ELIZABETH H S	MDCO	Common Stock	A - Award	D			4 531			38 970
2015-06-01	2015-05-28	4	KESSLER ARMIN M	MDCO	Stock Option (right-to-buy)	A - Award	D	28,14		11 512		11 512
2015-06-01	2015-05-28	4	KESSLER ARMIN M	MDCO	Common Stock	A - Award	D			4 531			129 930
2015-06-01	2015-05-28	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	A - Award	D	28,14		11 512		11 512
2015-06-01	2015-05-28	4	HUGIN ROBERT J	MDCO	Common Stock	A - Award	D			4 531			86 470
2015-06-01	2015-05-28	4	Savage Robert G.	MDCO	Stock Option (right-to-buy)	A - Award	D	28,14		11 512		11 512
2015-06-01	2015-05-28	4	Savage Robert G.	MDCO	Common Stock	A - Award	D			4 531			27 720
2015-06-01	2015-05-28	4	Spigelman Melvin K	MDCO	Stock Option (right-to-buy)	A - Award	D	28,14		11 512		11 512
2015-06-01	2015-05-28	4	Spigelman Melvin K	MDCO	Common Stock	A - Award	D			4 531			38 970
2015-06-01	2015-05-28	4	Shigeta Hiroaki	MDCO	Stock Option (right-to-buy)	A - Award	D	28,14		11 512		11 512
2015-06-01	2015-05-28	4	Shigeta Hiroaki	MDCO	Common Stock	A - Award	D			4 531			31 470
2015-06-01	2015-05-28	4	Kelly John C.	MDCO	Stock Option (right-to-buy)	A - Award	D	28,14		16 512		16 512
2015-06-01	2015-05-28	4	Kelly John C.	MDCO	Common Stock	A - Award	D			4 531			18 056
2015-05-26	2015-05-22	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	M - Exercise	D	21,45		−15 000		0
2015-05-26	2015-05-22	4	HUGIN ROBERT J	MDCO	Common Stock	M - Exercise	D		21,4500	15 000	322		81 939
2015-05-21	2015-05-19	4	CROUSE WILLIAM	MDCO	Stock Option (right-to-buy)	M - Exercise	D	21,45		−15 000		0
2015-05-21	2015-05-19	4	CROUSE WILLIAM	MDCO	Common Stock	S - Sale	D		26,8601	−15 000	−403		34 439
2015-05-21	2015-05-19	4	CROUSE WILLIAM	MDCO	Common Stock	M - Exercise	D		21,4500	15 000	322		49 439
2015-05-21	2015-05-19	4	WYATT ELIZABETH H S	MDCO	Stock Option (right-to-buy)	M - Exercise	D	21,45		−15 000		0
2015-05-21	2015-05-19	4	WYATT ELIZABETH H S	MDCO	Common Stock	S - Sale	D		26,7988	−15 000	−402		34 439
2015-05-21	2015-05-19	4	WYATT ELIZABETH H S	MDCO	Common Stock	M - Exercise	D		21,4500	15 000	322		49 439
2015-05-21	2015-05-20	4	Savage Robert G.	MDCO	Stock Option (right-to-buy)	M - Exercise	D	21,45		−15 000		0
2015-05-21	2015-05-20	4	Savage Robert G.	MDCO	Common Stock	S - Sale	D		26,7764	−15 000	−402		23 189
2015-05-21	2015-05-20	4	Savage Robert G.	MDCO	Common Stock	M - Exercise	D		21,4500	15 000	322		38 189
2015-05-15	2015-05-13	4	KESSLER ARMIN M	MDCO	Stock Option (right-to-buy)	M - Exercise	D	21,45		−15 000		0
2015-05-15	2015-05-13	4	KESSLER ARMIN M	MDCO	Common Stock	S - Sale	D		25,8696	−12 475	−323		125 399
2015-05-15	2015-05-13	4	KESSLER ARMIN M	MDCO	Common Stock	M - Exercise	D		21,4500	15 000	322		137 874
2015-05-05	2015-05-01	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,27		−16 667		99 999
2015-05-05	2015-05-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		26,5212	−16 667	−442		324 476
2015-05-05	2015-05-01	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		18,2700	16 667	305		341 143
2015-04-20	2015-04-16	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		30,0000	−1 281	−38		24 732
2015-04-03	2015-04-01	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,27		−16 667		116 666
2015-04-03	2015-04-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		27,5753	−16 667	−460		324 476
2015-04-03	2015-04-01	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		18,2700	16 667	305		341 143
2015-04-01	2015-03-30	4	WYATT ELIZABETH H S	MDCO	Stock Option (right-to-buy)	M - Exercise	D	22,68		−20 000		0
2015-04-01	2015-03-30	4	WYATT ELIZABETH H S	MDCO	Common Stock	S - Sale	D		28,0767	−20 000	−562		34 439
2015-04-01	2015-03-30	4	WYATT ELIZABETH H S	MDCO	Common Stock	M - Exercise	D		22,6750	20 000	454		54 439
2015-03-25	2015-03-23	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	18,27		−16 667		133 333
2015-03-25	2015-03-23	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		30,6230	−16 667	−510		324 476
2015-03-25	2015-03-23	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		18,2700	16 667	305		341 143
2015-03-25	2015-03-23	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		30,7801	−34 773	−1 070		102 844
2015-03-18	2015-03-16	4	Savage Robert G.	MDCO	Common Stock	S - Sale	D		28,9820	−7 500	−217		23 189
2015-03-03	2015-03-02	4	SBLENDORIO GLENN	MDCO	Common Stock	F - Taxes	D		28,9301	−8 138	−235		137 617
2015-03-03	2015-03-01	4	SBLENDORIO GLENN	MDCO	Stock Option (right-to-buy)	A - Award	D	28,77		93 750		93 750
2015-03-03	2015-03-01	4	SBLENDORIO GLENN	MDCO	Common Stock	A - Award	D			15 641			145 755
2015-03-03	2015-02-27	4	SBLENDORIO GLENN	MDCO	Common Stock	A - Award	D		22,3200	475	11		130 114
2015-03-03	2015-03-02	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		28,9301	−2 019	−58		26 013
2015-03-03	2015-03-02	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		28,7800	−2 988	−86		28 032
2015-03-03	2015-03-01	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	A - Award	D	28,77		29 688		29 688
2015-03-03	2015-03-01	4	O'Connor William Bernard	MDCO	Common Stock	A - Award	D			4 953			31 020
2015-03-03	2015-03-02	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		28,9301	−16 470	−476		324 476
2015-03-03	2015-03-01	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	A - Award	D	28,77		234 375		234 375
2015-03-03	2015-03-01	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D			39 103			340 946
2015-03-03	2015-02-27	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		22,3200	475	11		301 843
2015-03-03	2015-03-01	4	Frazier Jeff	MDCO	Stock Option (right-to-buy)	A - Award	D	28,77		29 688		29 688
2015-03-03	2015-03-01	4	Frazier Jeff	MDCO	Common Stock	A - Award	D			4 953			28 593
2015-03-03	2015-02-27	4	Frazier Jeff	MDCO	Common Stock	A - Award	D		22,3200	475	11		23 640
2015-03-03	2015-03-02	4	Rodin Stephen M	MDCO	Common Stock	F - Taxes	D		28,9301	−332	−10		9 807
2015-03-03	2015-03-01	4	Rodin Stephen M	MDCO	Stock Option (right-to-buy)	A - Award	D	28,77		5 000		5 000
2015-03-03	2015-03-01	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D			834			10 139
2015-03-03	2015-02-27	4	Rodin Stephen M	MDCO	Common Stock	A - Award	D		22,3200	475	11		9 305
2015-02-27		3	Rodin Stephen M	MDCO	Common Stock		D						17 660
2015-02-27		3	Rodin Stephen M	MDCO	Common Stock		D						17 660
2015-02-27		3	Frazier Jeff	MDCO	Common Stock		D						46 330
2015-02-27		3	Frazier Jeff	MDCO	Common Stock		D						46 330
2015-02-26	2015-02-24	4	SBLENDORIO GLENN	MDCO	Common Stock	F - Taxes	D		28,6682	−4 008	−115		129 639
2015-02-26	2015-02-24	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		28,6682	−12 306	−353		301 368
2015-02-26	2015-02-24	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		28,6682	−1 179	−34		26 067
2015-02-20	2015-02-18	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		28,3819	−624	−18		27 246
2015-02-20	2015-02-18	4	SBLENDORIO GLENN	MDCO	Common Stock	F - Taxes	D		28,3742	−1 672	−47		133 647
2015-02-20	2015-02-18	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		28,3824	−5 045	−143		313 674
2014-09-03	2014-08-29	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		21,7700	415	9		318 719
2014-09-03	2014-08-29	4	SBLENDORIO GLENN	MDCO	Common Stock	A - Award	D		21,7700	295	6		135 319
2014-09-03	2014-08-29	4	Furse Brent	MDCO	Common Stock	A - Award	D		21,7700	415	9		41 044
2014-06-02	2014-05-29	4	CROUSE WILLIAM	MDCO	Stock Option (right-to-buy)	A - Award	D	27,78		10 016		10 016
2014-06-02	2014-05-29	4	CROUSE WILLIAM	MDCO	Common Stock	A - Award	D			4 590			34 439
2014-06-02	2014-05-29	4	WYATT ELIZABETH H S	MDCO	Stock Option (right-to-buy)	A - Award	D	27,78		15 016		15 016
2014-06-02	2014-05-29	4	WYATT ELIZABETH H S	MDCO	Common Stock	A - Award	D			4 590			34 439
2014-06-02	2014-05-29	4	KESSLER ARMIN M	MDCO	Stock Option (right-to-buy)	A - Award	D	27,78		10 016		10 016
2014-06-02	2014-05-29	4	KESSLER ARMIN M	MDCO	Common Stock	A - Award	D			4 590			122 874
2014-06-02	2014-05-29	4	HUGIN ROBERT J	MDCO	Stock Option (right-to-buy)	A - Award	D	27,00		10 016		10 016
2014-06-02	2014-05-29	4	HUGIN ROBERT J	MDCO	Common Stock	A - Award	D			4 590			66 939
2014-06-02	2014-05-29	4	Savage Robert G.	MDCO	Stock Option (right-to-buy)	A - Award	D	27,78		10 016		10 016
2014-06-02	2014-05-29	4	Savage Robert G.	MDCO	Common Stock	A - Award	D			4 590			30 689
2014-06-02	2014-05-29	4	Spigelman Melvin K	MDCO	Stock Option (right-to-buy)	A - Award	D	27,78		10 016		10 016
2014-06-02	2014-05-29	4	Spigelman Melvin K	MDCO	Common Stock	A - Award	D			4 590			34 439
2014-06-02	2014-05-29	4	Shigeta Hiroaki	MDCO	Stock Option (right-to-buy)	A - Award	D	27,78		10 016		10 016
2014-06-02	2014-05-29	4	Shigeta Hiroaki	MDCO	Common Stock	A - Award	D			4 590			26 939
2014-06-02	2014-05-29	4	Kelly John C.	MDCO	Stock Option (right-to-buy)	A - Award	D	27,78		10 016		10 016
2014-06-02	2014-05-29	4	Kelly John C.	MDCO	Common Stock	A - Award	D			4 590			13 525
2014-03-05		3/A	Furse Brent	MDCO	Common Stock		D						40 629
2014-03-05	2014-03-03	4	Kusiak Victoria	MDCO	Stock Option (right-to-buy)	A - Award	D	30,07		20 000		20 000
2014-03-05	2014-03-03	4	Heiman Cornelis	MDCO	Stock Option (right-to-buy)	A - Award	D	30,07		30 000		30 000
2014-03-05	2014-03-03	4	Heiman Cornelis	MDCO	Common Stock	A - Award	D			20 000			31 457
2014-03-05	2014-03-03	4	Furse Brent	MDCO	Stock Option (right-to-buy)	A - Award	D	30,07		20 000		20 000
2014-03-04	2014-03-03	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		30,0985	−8 643	−260		318 304
2014-03-04	2014-03-01	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	A - Award	D	30,55		131 483		131 483
2014-03-04	2014-03-01	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D			60 082			326 947
2014-03-04	2014-02-28	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		25,9700	392	10		266 865
2014-03-04	2014-03-03	4	SBLENDORIO GLENN	MDCO	Common Stock	F - Taxes	D		30,0985	−3 549	−107		135 024
2014-03-04	2014-03-01	4	SBLENDORIO GLENN	MDCO	Stock Option (right-to-buy)	A - Award	D	30,55		57 736		57 736
2014-03-04	2014-03-01	4	SBLENDORIO GLENN	MDCO	Common Stock	A - Award	D			26 383			138 573
2014-03-04	2014-02-28	4	SBLENDORIO GLENN	MDCO	Common Stock	A - Award	D		25,9700	392	10		112 190
2014-03-04	2014-03-03	4	Antinori Paul Michael	MDCO	Common Stock	F - Taxes	D		29,9900	−12	−0		31 080
2014-03-04	2014-03-03	4	Antinori Paul Michael	MDCO	Common Stock	F - Taxes	D		30,0786	−1 086	−33		31 092
2014-03-04	2014-03-01	4	Antinori Paul Michael	MDCO	Stock Option (right-to-buy)	A - Award	D	30,55		8 059		8 059
2014-03-04	2014-03-01	4	Antinori Paul Michael	MDCO	Common Stock	A - Award	D			3 682			32 178
2014-03-04	2014-02-25	4	Antinori Paul Michael	MDCO	Common Stock	F - Taxes	D		30,4946	−1 641	−50		28 496
2014-03-04	2014-03-03	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		30,0985	−1 442	−43		27 870
2014-03-04	2014-03-03	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		30,3100	−2 968	−90		29 312
2014-03-04	2014-03-01	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	A - Award	D	30,55		22 987		22 987
2014-03-04	2014-03-01	4	O'Connor William Bernard	MDCO	Common Stock	A - Award	D			10 504			32 280
2014-03-04		3	Kusiak Victoria	MDCO	Common Stock		D						7 038
2014-03-04		3	Kusiak Victoria	MDCO	Common Stock		D						7 038
2014-03-04		3	Heiman Cornelis	MDCO	Common Stock		D						22 914
2014-03-04		3	Heiman Cornelis	MDCO	Common Stock		D						22 914
2014-03-04		3	Furse Brent	MDCO	Common Stock		D						81 258
2014-03-04		3	Furse Brent	MDCO	Common Stock		D						81 258
2014-02-27	2014-02-25	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		30,4946	−12 369	−377		266 473
2014-02-27	2014-02-25	4	SBLENDORIO GLENN	MDCO	Common Stock	F - Taxes	D		30,4946	−4 142	−126		111 798
2014-02-27	2014-02-25	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		30,4946	−1 650	−50		21 776
2014-02-21	2014-02-20	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		29,7315	−2 603	−77		278 842
2014-02-21	2014-02-19	4	MEANWELL CLIVE	MDCO	Common Stock	F - Taxes	D		29,9809	−6 328	−190		281 445
2014-02-21	2014-02-20	4	SBLENDORIO GLENN	MDCO	Common Stock	F - Taxes	D		29,7315	−935	−28		115 940
2014-02-21	2014-02-19	4	SBLENDORIO GLENN	MDCO	Common Stock	F - Taxes	D		29,9905	−1 530	−46		116 875
2014-02-21	2014-02-20	4	Antinori Paul Michael	MDCO	Common Stock	F - Taxes	D		29,7315	−542	−16		30 137
2014-02-21	2014-02-19	4	Antinori Paul Michael	MDCO	Common Stock	F - Taxes	D		30,0300	−350	−11		30 679
2014-02-21	2014-02-20	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		29,7315	−760	−23		23 426
2014-02-21	2014-02-19	4	O'Connor William Bernard	MDCO	Common Stock	F - Taxes	D		30,0220	−872	−26		24 186
2014-02-05	2014-02-03	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		34,2916	−10 000	−343		287 773
2014-01-23	2014-01-21	4	Antinori Paul Michael	MDCO	Stock Option (right-to-buy)	M - Exercise	D	17,45		−7 000		6 333
2014-01-23	2014-01-21	4	Antinori Paul Michael	MDCO	Stock Option (right-to-buy)	M - Exercise	D	14,82		−20 000		8 330
2014-01-23	2014-01-21	4	Antinori Paul Michael	MDCO	Stock Option (right-to-buy)	M - Exercise	D	7,31		−10 500		2 000
2014-01-23	2014-01-21	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		38,0526	−383	−15		31 029
2014-01-23	2014-01-21	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		37,8171	−7 000	−265		31 412
2014-01-23	2014-01-21	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		17,4500	7 000	122		38 412
2014-01-23	2014-01-21	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		38,0907	−20 000	−762		31 412
2014-01-23	2014-01-21	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		14,8200	20 000	296		51 412
2014-01-23	2014-01-21	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		38,0024	−10 500	−399		31 412
2014-01-23	2014-01-21	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		7,3100	10 500	77		41 912
2014-01-16	2014-01-15	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	22,04		−1 250		10 833
2014-01-16	2014-01-15	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		40,0000	−1 250	−50		25 058
2014-01-16	2014-01-15	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		22,0400	1 250	28		26 308
2014-01-16	2014-01-14	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	17,45		−2 083		9 722
2014-01-16	2014-01-14	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	7,31		−1 094		729
2014-01-16	2014-01-14	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		38,8101	−3 177	−123		25 058
2014-01-16	2014-01-14	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		17,4500	2 083	36		28 235
2014-01-16	2014-01-14	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		7,3100	1 094	8		26 152
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	22,04		−7 917		12 083
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	17,45		−694		11 805
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	7,31		−365		1 823
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,36		−15 908		15 907
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,06		−15 000		15 000
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	17,04		−7 500		0
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Stock Option (right-to-buy)	M - Exercise	D	19,98		−25 000		25 000
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		40,0000	−72 384	−2 895		25 058
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		22,0400	7 917	174		97 442
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		17,4500	694	12		89 525
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		7,3100	365	3		88 831
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		19,3600	15 908	308		88 466
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		19,0600	15 000	286		72 558
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		17,0400	7 500	128		57 558
2014-01-14	2014-01-10	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		19,9800	25 000	500		50 058
2014-01-08	2014-01-07	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,02		−24 627		0
2014-01-08	2014-01-07	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		38,1268	−24 627	−939		297 773
2014-01-08	2014-01-07	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,0200	24 627	690		322 400
2014-01-08	2014-01-06	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,02		−3 302		24 627
2014-01-08	2014-01-06	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		38,1297	−3 302	−126		297 773
2014-01-08	2014-01-06	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,0200	3 302	93		301 075
2014-01-06	2014-01-03	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,02		−47 516		27 929
2014-01-06	2014-01-03	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		38,1946	−47 516	−1 815		297 773
2014-01-06	2014-01-03	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,0200	47 516	1 331		345 289
2014-01-06	2014-01-02	4	MEANWELL CLIVE	MDCO	Stock Option (right-to-buy)	M - Exercise	D	28,02		−24 555		75 445
2014-01-06	2014-01-02	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		37,9757	−10 000	−380		297 773
2014-01-06	2014-01-02	4	MEANWELL CLIVE	MDCO	Commom Stock	S - Sale	D		37,9757	−24 555	−932		307 773
2014-01-06	2014-01-02	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,0200	24 555	688		332 328
2013-12-17	2013-12-13	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		36,9102	−9 600	−354		31 412
2013-12-17	2013-12-12	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		37,0114	−10 000	−370		41 012
2013-12-11	2013-12-09	4	CROUSE WILLIAM	MDCO	Stock Option (right-to-buy)	M - Exercise	D	32,30		−12 500		0
2013-12-11	2013-12-09	4	CROUSE WILLIAM	MDCO	Common Stock	S - Sale	D		38,0017	−12 500	−475		29 849
2013-12-11	2013-12-09	4	CROUSE WILLIAM	MDCO	Common Stock	M - Exercise	D		32,3000	12 500	404		42 349
2013-12-06	2013-12-05	4	SBLENDORIO GLENN	MDCO	Stock Option (right-to-buy)	M - Exercise	D	20,11		−326		0
2013-12-06	2013-12-05	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		38,5000	−326	−13		118 405
2013-12-06	2013-12-05	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		20,1100	326	7		118 731
2013-12-06	2013-12-04	4	SBLENDORIO GLENN	MDCO	Stock Option (right-to-buy)	M - Exercise	D	20,11		−8 190		326
2013-12-06	2013-12-04	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		38,5000	−8 190	−315		118 405
2013-12-06	2013-12-04	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		20,1100	8 190	165		126 595
2013-12-04	2013-12-02	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		36,5764	−10 000	−366		307 773
2013-11-27	2013-11-26	4	MEANWELL CLIVE	MDCO	Option (Right-to-buy)	M - Exercise	D	28,01		−25 136		0
2013-11-27	2013-11-26	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		36,6600	−25 136	−921		317 773
2013-11-27	2013-11-26	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,0100	25 136	704		342 909
2013-11-27	2013-11-25	4	MEANWELL CLIVE	MDCO	Option (Right-to-buy)	M - Exercise	D	28,01		−99 864		25 136
2013-11-27	2013-11-25	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		36,7100	−99 864	−3 666		317 773
2013-11-27	2013-11-25	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		28,0100	99 864	2 797		417 637
2013-11-27	2013-11-25	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		36,7100	−10 000	−367		317 773
2013-11-27	2013-11-25	4	Shigeta Hiroaki	MDCO	Option (Right-to-buy)	M - Exercise	D	21,14		−17 039		0
2013-11-27	2013-11-25	4	Shigeta Hiroaki	MDCO	Common Stock	S - Sale	D		37,1900	−17 039	−634		22 349
2013-11-27	2013-11-25	4	Shigeta Hiroaki	MDCO	Common Stock	M - Exercise	D		21,1400	17 039	360		39 388
2013-11-20	2013-11-18	4	SBLENDORIO GLENN	MDCO	Option (Right-to-buy)	M - Exercise	D	20,11		−16 484		8 516
2013-11-20	2013-11-18	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		38,5000	−16 484	−635		118 405
2013-11-20	2013-11-18	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		20,1100	16 484	331		134 889
2013-11-18	2013-11-14	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		38,0000	−1 667	−63		118 405
2013-10-29	2013-10-25	4	SBLENDORIO GLENN	MDCO	Option (Right-to-buy)	M - Exercise	D	17,04		−25 000		0
2013-10-29	2013-10-25	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		35,6900	−25 000	−892		120 072
2013-10-29	2013-10-25	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		17,0400	25 000	426		145 072
2013-10-29	2013-10-25	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		35,8900	−574	−21		120 072
2013-10-25	2013-10-23	4	O'Connor William Bernard	MDCO	Option (Right-to-Buy)	M - Exercise	D	17,45		−4 167		12 499
2013-10-25	2013-10-23	4	O'Connor William Bernard	MDCO	Option (Right-to-Buy)	M - Exercise	D	7,31		−2 187		2 188
2013-10-25	2013-10-23	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		35,0000	−4 167	−146		25 058
2013-10-25	2013-10-23	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		17,4500	4 167	73		29 225
2013-10-25	2013-10-23	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		35,0000	−2 187	−77		25 058
2013-10-25	2013-10-23	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		7,3100	2 187	16		27 245
2013-10-03	2013-10-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		33,4500	−7 500	−251		327 773
2013-10-01	2013-09-27	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		33,1600	−894	−30		51 012
2013-09-17	2013-09-13	4	Antinori Paul Michael	MDCO	Option (Right-to-Buy)	M - Exercise	D	28,60		−50 000		0
2013-09-17	2013-09-13	4	Antinori Paul Michael	MDCO	Option (Right-to-Buy)	M - Exercise	D	28,02		−23 500		0
2013-09-17	2013-09-13	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		34,5000	−73 500	−2 536		51 906
2013-09-17	2013-09-13	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		28,6000	50 000	1 430		125 406
2013-09-17	2013-09-13	4	Antinori Paul Michael	MDCO	Commmon Stock	M - Exercise	D		28,0200	23 500	658		75 406
2013-09-05	2013-09-03	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		31,8500	−7 500	−239		335 273
2013-09-03	2013-08-30	4	MEANWELL CLIVE	MDCO	Common Stock	J - Other	D		26,7700	396	11		342 773
2013-09-03	2013-08-30	4	SBLENDORIO GLENN	MDCO	Common Stock	J - Other	D		26,7700	212	6		120 646
2013-08-05	2013-08-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		31,2600	−7 500	−234		342 377
2013-07-09	2013-07-08	4	Antinori Paul Michael	MDCO	Option (Right-to-buy)	M - Exercise	D	23,77		−36 000		0
2013-07-09	2013-07-08	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		33,0000	−36 000	−1 188		51 906
2013-07-09	2013-07-08	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		23,7700	36 000	856		87 906
2013-07-02	2013-07-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		31,2500	−7 500	−234		349 877
2013-06-13	2013-06-11	4	Antinori Paul Michael	MDCO	Option (Right-to-buy)	M - Exercise	D	22,47		−50 000		0
2013-06-13	2013-06-11	4	Antinori Paul Michael	MDCO	Option (Right-to-buy)	M - Exercise	D	12,95		−9 283		0
2013-06-13	2013-06-11	4	Antinori Paul Michael	MDCO	Option (Right-to-buy)	M - Exercise	D	19,36		−50 690		0
2013-06-13	2013-06-11	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		33,2800	−50 000	−1 664		51 906
2013-06-13	2013-06-11	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		22,4700	50 000	1 124		101 906
2013-06-13	2013-06-11	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		33,2900	−9 283	−309		51 906
2013-06-13	2013-06-11	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		12,9500	9 283	120		61 189
2013-06-13	2013-06-11	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		33,2900	−50 690	−1 687		51 906
2013-06-13	2013-06-11	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		19,3600	50 690	981		102 596
2013-05-31	2013-05-30	4	CROUSE WILLIAM	MDCO	Option (Right-to-buy)	A - Award	D	33,13		9 763		9 763
2013-05-31	2013-05-30	4	CROUSE WILLIAM	MDCO	Common Stock	A - Award	D			3 849			29 849
2013-05-31	2013-05-30	4	WYATT ELIZABETH H S	MDCO	Option (Right-to-buy)	A - Award	D	33,13		14 763		14 763
2013-05-31	2013-05-30	4	WYATT ELIZABETH H S	MDCO	Common Stock	A - Award	D			3 849			29 849
2013-05-31	2013-05-30	4	KESSLER ARMIN M	MDCO	Option (Right-to-buy)	A - Award	D	33,13		9 763		9 763
2013-05-31	2013-05-30	4	KESSLER ARMIN M	MDCO	Common Stock	A - Award	D			3 849			118 284
2013-05-31	2013-05-29	4	KESSLER ARMIN M	MDCO	Option (Right-to-buy)	M - Exercise	D	23,00		−12 500		0
2013-05-31	2013-05-29	4	KESSLER ARMIN M	MDCO	Common Stock	S - Sale	D		33,0500	−8 750	−289		114 435
2013-05-31	2013-05-29	4	KESSLER ARMIN M	MDCO	Common Stock	M - Exercise	D		23,0000	12 500	288		123 185
2013-05-31	2013-05-30	4	HUGIN ROBERT J	MDCO	Option (Right-to-buy)	A - Award	D	33,14		9 763		9 763
2013-05-31	2013-05-30	4	HUGIN ROBERT J	MDCO	Common Stock	A - Award	D			3 849			62 349
2013-05-31	2013-05-22	4	HUGIN ROBERT J	MDCO	Option (Right-to-buy)	M - Exercise	D	23,00		−12 500		0
2013-05-31	2013-05-22	4	HUGIN ROBERT J	MDCO	Common Stock	M - Exercise	D		23,0000	12 500	288		58 500
2013-05-31	2013-05-30	4	Savage Robert G.	MDCO	Option (Right-to-buy)	A - Award	D	33,13		9 763		9 763
2013-05-31	2013-05-30	4	Savage Robert G.	MDCO	Common Stock	A - Award	D			3 849			26 099
2013-05-31	2013-05-30	4	Spigelman Melvin K	MDCO	Option (Right-to-buy)	A - Award	D	33,13		9 763		9 763
2013-05-31	2013-05-30	4	Spigelman Melvin K	MDCO	Common Stock	A - Award	D			3 849			29 849
2013-05-31	2013-05-30	4	Shigeta Hiroaki	MDCO	Option (Right-to-buy)	A - Award	D	33,13		9 763		9 763
2013-05-31	2013-05-30	4	Shigeta Hiroaki	MDCO	Common Stock	A - Award	D			3 849			22 349
2013-05-31	2013-05-30	4	Kelly John C.	MDCO	Option (Right-to-buy)	A - Award	D	33,13		9 763		9 763
2013-05-31	2013-05-30	4	Kelly John C.	MDCO	Common Stock	A - Award	D			3 849			8 935
2013-05-13	2013-05-10	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		37,0000	−2 709	−100		120 434
2013-05-13	2013-05-09	4	Antinori Paul Michael	MDCO	Option (Right-to-buy)	M - Exercise	D	17,04		−5 000		0
2013-05-13	2013-05-09	4	Antinori Paul Michael	MDCO	Option (Right-to-buy)	M - Exercise	D	18,27		−30 000		0
2013-05-13	2013-05-09	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		34,9000	−5 000	−174		51 906
2013-05-13	2013-05-09	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		17,0400	5 000	85		56 906
2013-05-13	2013-05-09	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		34,9000	−30 000	−1 047		51 906
2013-05-13	2013-05-09	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		18,2700	30 000	548		81 906
2013-05-13	2013-05-09	4	O'Connor William Bernard	MDCO	Option (Right-to-buy)	M - Exercise	D	12,95		−4 654		0
2013-05-13	2013-05-09	4	O'Connor William Bernard	MDCO	Option (Right-to-buy)	M - Exercise	D	19,98		−25 000		50 000
2013-05-13	2013-05-09	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		35,0000	−4 654	−163		25 058
2013-05-13	2013-05-09	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		12,9500	4 654	60		29 712
2013-05-13	2013-05-09	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		35,0000	−25 000	−875		25 058
2013-05-13	2013-05-09	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		19,9800	25 000	500		50 058
2013-05-02	2013-05-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		33,4700	−7 500	−251		357 377
2013-04-18	2013-04-16	4	HUGIN ROBERT J	MDCO	Option (Right to Buy)	M - Exercise	D	17,19		−1 667		0
2013-04-18	2013-04-16	4	HUGIN ROBERT J	MDCO	Common Stock	M - Exercise	D		17,1900	1 667	29		46 000
2013-04-04	2013-04-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		33,3700	−7 500	−250		364 877
2013-03-28	2013-03-26	4	Shigeta Hiroaki	MDCO	Options (Right to buy)	M - Exercise	D	18,18		−18 259		0
2013-03-28	2013-03-26	4	Shigeta Hiroaki	MDCO	Options (Right to buy)	M - Exercise	D	18,30		−7 500		0
2013-03-28	2013-03-26	4	Shigeta Hiroaki	MDCO	Options (Right to buy)	M - Exercise	D	19,60		−7 500		0
2013-03-28	2013-03-26	4	Shigeta Hiroaki	MDCO	Common Stock	S - Sale	D		33,5000	−18 259	−612		18 500
2013-03-28	2013-03-26	4	Shigeta Hiroaki	MDCO	Common Stock	M - Exercise	D		18,1800	18 259	332		36 759
2013-03-28	2013-03-26	4	Shigeta Hiroaki	MDCO	Common Stock	S - Sale	D		33,5000	−7 500	−251		18 500
2013-03-28	2013-03-26	4	Shigeta Hiroaki	MDCO	Common Stock	S - Sale	D		33,5000	−7 500	−251		18 500
2013-03-28	2013-03-26	4	Shigeta Hiroaki	MDCO	Common Stock	M - Exercise	D		18,3000	7 500	137		26 000
2013-03-28	2013-03-26	4	Shigeta Hiroaki	MDCO	Common Stock	M - Exercise	D		19,6000	7 500	147		26 000
2013-03-15	2013-03-13	4	Savage Robert G.	MDCO	Common Stock	S - Sale	D		31,7700	−3 750	−119		22 250
2013-03-13	2013-03-11	4	CROUSE WILLIAM	MDCO	Option (right to buy)	M - Exercise	D	23,00		−12 500		0
2013-03-13	2013-03-11	4	CROUSE WILLIAM	MDCO	Common Stock	S - Sale	D		32,2300	−12 500	−403		26 000
2013-03-13	2013-03-11	4	CROUSE WILLIAM	MDCO	Common Stock	M - Exercise	D		23,0000	12 500	288		38 500
2013-03-05	2013-03-01	4	MEANWELL CLIVE	MDCO	Options (Right to Buy)	A - Award	D	31,49	31,4900	64 568	2 033	64 568
2013-03-05	2013-03-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		31,5600	−7 500	−237		372 377
2013-03-05	2013-03-01	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D			65 354			379 877
2013-03-05	2013-02-28	4	MEANWELL CLIVE	MDCO	Common Stock	J - Other	D		22,3900	474	11		314 523
2013-03-05	2013-03-01	4	SBLENDORIO GLENN	MDCO	Option (Right to Buy)	A - Award	D	31,49	31,4900	36 896	1 162	36 896
2013-03-05	2013-03-01	4	SBLENDORIO GLENN	MDCO	Common Stock	A - Award	D			37 345			123 143
2013-03-05	2013-02-28	4	SBLENDORIO GLENN	MDCO	Common Stock	J - Other	D		22,3900	474	11		85 798
2013-03-05	2013-03-01	4	Antinori Paul Michael	MDCO	Option (Right to buy)	A - Award	D	31,49	31,4900	8 235	259	8 235
2013-03-05	2013-03-01	4	Antinori Paul Michael	MDCO	Common Stock	A - Award	D			8 335			51 906
2013-03-05	2013-02-28	4	Antinori Paul Michael	MDCO	Common Stock	J - Other	D		22,3900	196	4		43 571
2013-03-05	2013-03-01	4	O'Connor William Bernard	MDCO	Option (Right to Buy)	A - Award	D	31,49	31,4900	10 761	339	10 761
2013-03-05	2013-03-01	4	O'Connor William Bernard	MDCO	Common Stock	A - Award	D			10 892			25 058
2013-03-01	2013-02-27	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		31,0900	−4 872	−151		14 166
2013-02-26	2013-02-25	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		31,1700	−12 303	−383		314 049
2013-02-26	2013-02-26	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		30,8500	−1 033	−32		85 324
2013-02-26	2013-02-25	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		31,1600	−5 580	−174		86 357
2013-02-26	2013-02-25	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		31,2200	−1 067	−33		43 375
2013-02-26	2013-02-25	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		31,1700	−1 182	−37		19 038
2013-02-22	2013-02-20	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		32,4200	−8 292	−269		326 352
2013-02-22	2013-02-20	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		32,4200	−2 793	−91		91 937
2013-02-22	2013-02-20	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		32,4200	−1 027	−33		44 442
2013-02-22	2013-02-21	4	O'Connor William Bernard	MDCO	Option (right to buy)	M - Exercise	D	17,45		−3 473		16 666
2013-02-22	2013-02-21	4	O'Connor William Bernard	MDCO	Option (right to buy)	M - Exercise	D	7,31		−1 823		4 375
2013-02-22	2013-02-21	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		32,9000	−3 473	−114		20 220
2013-02-22	2013-02-21	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		17,4500	3 473	61		23 693
2013-02-22	2013-02-21	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		32,9000	−1 823	−60		20 220
2013-02-22	2013-02-21	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		7,3100	1 823	13		22 043
2013-02-22	2013-02-20	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		32,4200	−570	−18		20 220
2013-02-21	2013-02-19	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		31,8400	−6 232	−198		334 644
2013-02-21	2013-02-20	4	Savage Robert G.	MDCO	Option (right to buy)	M - Exercise	D	23,00		−6 250		0
2013-02-21	2013-02-20	4	Savage Robert G.	MDCO	Common Stock	S - Sale	D		32,5000	−6 250	−203		26 000
2013-02-21	2013-02-20	4	Savage Robert G.	MDCO	Common Stock	M - Exercise	D		23,0000	6 250	144		32 250
2013-02-21	2013-02-20	4	SBLENDORIO GLENN	MDCO	Option(right to buy)	M - Exercise	D	20,11		−25 000		25 000
2013-02-21	2013-02-20	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		32,5100	−25 000	−813		94 730
2013-02-21	2013-02-20	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		20,1100	25 000	503		119 730
2013-02-21	2013-02-19	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		31,8100	−2 552	−81		94 730
2013-02-21	2013-02-20	4	Antinori Paul Michael	MDCO	Option (right to buy)	M - Exercise	D	18,27		−6 500		0
2013-02-21	2013-02-20	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		32,5000	−6 500	−211		45 469
2013-02-21	2013-02-20	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		18,2700	6 500	119		51 969
2013-02-21	2013-02-19	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		31,8100	−569	−18		45 469
2013-02-21	2013-02-19	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		31,8000	−1 143	−36		20 790
2013-02-19	2013-02-14	4	Antinori Paul Michael	MDCO	Option (right to buy)	M - Exercise	D	27,81		−6 000		0
2013-02-19	2013-02-14	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		30,9000	−6 000	−185		46 038
2013-02-19	2013-02-14	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		27,8100	6 000	167		52 038
2013-02-05	2013-02-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		29,8300	−5 000	−149		340 876
2013-02-05	2013-02-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		30,0400	−2 500	−75		345 876
2013-01-17	2013-01-16	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		30,0000	−2 500	−75		348 376
2013-01-17	2013-01-16	4	Savage Robert G.	MDCO	Option (right to buy)	M - Exercise	D	23,00		−6 250		6 250
2013-01-17	2013-01-16	4	Savage Robert G.	MDCO	Option (right to buy)	M - Exercise	D	17,19		−5 000		0
2013-01-17	2013-01-16	4	Savage Robert G.	MDCO	Common Stock	S - Sale	D		30,0000	−6 250	−188		26 000
2013-01-17	2013-01-16	4	Savage Robert G.	MDCO	Common Stock	M - Exercise	D		23,0000	6 250	144		32 250
2013-01-17	2013-01-16	4	Savage Robert G.	MDCO	Common Stock	S - Sale	D		30,0000	−5 000	−150		26 000
2013-01-17	2013-01-16	4	Savage Robert G.	MDCO	Common Stock	M - Exercise	D		17,1900	5 000	86		31 000
2013-01-17	2013-01-16	4	SBLENDORIO GLENN	MDCO	Common stock	M - Exercise	D	20,11		−100 000		50 000
2013-01-17	2013-01-16	4	SBLENDORIO GLENN	MDCO	Option (right to buy)	M - Exercise	D	19,36		−25 000		24 495
2013-01-17	2013-01-16	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		30,0000	−100 000	−3 000		97 282
2013-01-17	2013-01-16	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		20,1100	100 000	2 011		197 282
2013-01-17	2013-01-16	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		30,0000	−25 000	−750		97 282
2013-01-17	2013-01-16	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		19,3600	25 000	484		122 282
2013-01-17	2013-01-15	4	Antinori Paul Michael	MDCO	Option (right to buy)	M - Exercise	D	18,27		−6 000		6 500
2013-01-17	2013-01-15	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		29,5000	−6 000	−177		46 038
2013-01-17	2013-01-15	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		18,2700	6 000	110		52 038
2013-01-17	2013-01-15	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		29,9000	−3 781	−113		46 038
2013-01-17	2013-01-16	4	O'Connor William Bernard	MDCO	Option (right to buy)	M - Exercise	D	17,45		−13 194		20 139
2013-01-17	2013-01-16	4	O'Connor William Bernard	MDCO	Common stock	M - Exercise	D	7,31		−11 302		6 198
2013-01-17	2013-01-16	4	O'Connor William Bernard	MDCO	Option (right to buy)	M - Exercise	D	19,98		−25 000		75 000
2013-01-17	2013-01-16	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		30,0000	−13 194	−396		21 933
2013-01-17	2013-01-16	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		17,4500	13 194	230		35 127
2013-01-17	2013-01-16	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		30,0000	−11 302	−339		21 933
2013-01-17	2013-01-16	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		7,3100	11 302	83		33 235
2013-01-17	2013-01-16	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		30,0000	−25 000	−750		21 933
2013-01-17	2013-01-16	4	O'Connor William Bernard	MDCO	Common Stock	M - Exercise	D		19,9800	25 000	500		46 933
2013-01-10	2013-01-08	4	Savage Robert G.	MDCO	Option (right to buy)	M - Exercise	D	17,19		−5 000		5 000
2013-01-10	2013-01-08	4	Savage Robert G.	MDCO	Common Stock	S - Sale	D		27,5000	−5 000	−138		26 000
2013-01-10	2013-01-08	4	Savage Robert G.	MDCO	Common Stock	M - Exercise	D		17,1900	5 000	86		31 000
2013-01-10	2013-01-08	4	SBLENDORIO GLENN	MDCO	Option (right to buy)	M - Exercise	D	19,36		−25 000		49 495
2013-01-10	2013-01-08	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		28,0700	−25 000	−702		97 282
2013-01-10	2013-01-08	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		19,3600	25 000	484		122 282
2013-01-10	2013-01-08	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		27,9000	−3 500	−98		49 819
2013-01-04	2013-01-02	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		24,2200	−5 000	−121		350 876
2012-12-18	2012-12-14	4	CROUSE WILLIAM	MDCO	Option (right to buy)	M - Exercise	D	17,19		−20 000		0
2012-12-18	2012-12-14	4	CROUSE WILLIAM	MDCO	Common Stock	S - Sale	D		21,8900	−20 000	−438		26 000
2012-12-18	2012-12-14	4	CROUSE WILLIAM	MDCO	Common Stock	M - Exercise	D		17,1900	20 000	344		46 000
2012-12-18	2012-12-14	4	KESSLER ARMIN M	MDCO	Common Stock	S - Sale	D		21,7600	−11 500	−250		110 685
2012-11-28	2012-11-26	4	MEANWELL CLIVE	MDCO	Option (right to buy)	M - Exercise	D	15,50		−13 593		0
2012-11-28	2012-11-26	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		21,0200	−13 593	−286		355 876
2012-11-28	2012-11-26	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		15,5000	13 593	211		369 469
2012-10-29	2012-10-25	4	MEANWELL CLIVE	MDCO	Option (right to buy)	M - Exercise	D	15,50		−13 600		13 593
2012-10-29	2012-10-25	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		23,0900	−13 600	−314		355 876
2012-10-29	2012-10-25	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		15,5000	13 600	211		369 476
2012-09-26	2012-09-25	4	MEANWELL CLIVE	MDCO	Option (right to buy)	M - Exercise	D	15,50		−13 600		27 193
2012-09-26	2012-09-25	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		26,3100	−13 600	−358		355 876
2012-09-26	2012-09-25	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		15,5000	13 600	211		369 476
2012-09-19	2012-09-17	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		26,0400	−559	−15		53 319
2012-09-04	2012-08-31	4	MEANWELL CLIVE	MDCO	Common Stock	J - Other	D		18,4400	576	11		355 876
2012-09-04	2012-08-30	4	MEANWELL CLIVE	MDCO	Option (right to buy)	M - Exercise	D	15,50		−13 600		40 793
2012-09-04	2012-08-30	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		25,3300	−13 600	−344		355 300
2012-09-04	2012-08-30	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		15,5000	13 600	211		368 900
2012-09-04	2012-08-31	4	SBLENDORIO GLENN	MDCO	Common Stock	J - Other	D		18,4400	405	7		97 282
2012-09-04	2012-08-31	4	Antinori Paul Michael	MDCO	Common Stock	J - Other	D		18,4400	383	7		53 878
2012-08-23	2012-08-21	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		25,2500	−3 000	−76		53 495
2012-08-16	2012-08-15	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		25,4500	−662	−17		56 495
2012-08-16	2012-08-15	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		25,3000	−2 842	−72		57 157
2012-08-16	2012-08-14	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		25,2500	−2 158	−54		59 999
2012-08-14	2012-08-10	4	SBLENDORIO GLENN	MDCO	Option(right to buy)	M - Exercise	D	17,45		−25 000		65 000
2012-08-14	2012-08-10	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		25,1500	−25 000	−629		96 877
2012-08-14	2012-08-10	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		17,4500	25 000	436		121 877
2012-08-14	2012-08-10	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		25,0900	−8 989	−226		96 877
2012-08-14	2012-08-10	4	Antinori Paul Michael	MDCO	Option (right to buy)	M - Exercise	D	15,50		−4 500		0
2012-08-14	2012-08-10	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		25,0000	−4 500	−112		62 157
2012-08-14	2012-08-10	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		15,5000	4 500	70		66 657
2012-08-08	2012-08-06	4	Savage Robert G.	MDCO	Option (right to buy)	M - Exercise	D	17,19		−10 000		10 000
2012-08-08	2012-08-06	4	Savage Robert G.	MDCO	Common Stock	S - Sale	D		24,9400	−10 000	−249		26 000
2012-08-08	2012-08-06	4	Savage Robert G.	MDCO	Common Stock	M - Exercise	D		17,1900	10 000	172		36 000
2012-07-27	2012-07-25	4	SBLENDORIO GLENN	MDCO	Option (right to buy)	M - Exercise	D	19,36		−25 000		74 495
2012-07-27	2012-07-25	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		25,1500	−25 000	−629		105 866
2012-07-27	2012-07-25	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		19,3600	25 000	484		130 866
2012-07-05	2012-07-02	4	MEANWELL CLIVE	MDCO	Option (right to buy)	M - Exercise	D	15,50		−68 607		54 393
2012-07-05	2012-07-02	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		23,0300	−5 000	−115		355 300
2012-07-05	2012-07-02	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		22,7800	−68 607	−1 563		360 300
2012-07-05	2012-07-02	4	MEANWELL CLIVE	MDCO	Common Stock	M - Exercise	D		15,5000	68 607	1 063		428 907
2012-06-04	2012-06-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		21,7200	−5 000	−109		360 300
2012-05-24	2012-05-22	4	CROUSE WILLIAM	MDCO	Option (right to buy)	A - Award	D	0,00		12 039		12 039
2012-05-24	2012-05-22	4	CROUSE WILLIAM	MDCO	Common Stock	A - Award	D			5 086			26 000
2012-05-24	2012-05-22	4	WYATT ELIZABETH H S	MDCO	Option (right to buy)	A - Award	D	21,14		12 039		12 039
2012-05-24	2012-05-22	4	WYATT ELIZABETH H S	MDCO	Common Stock	A - Award	D			5 086			26 000
2012-05-24	2012-05-22	4	KESSLER ARMIN M	MDCO	Option (right to buy)	A - Award	D	21,14		12 039		12 039
2012-05-24	2012-05-22	4	KESSLER ARMIN M	MDCO	Common Stock	A - Award	D			5 086			122 185
2012-05-24	2012-05-22	4	HUGIN ROBERT J	MDCO	Option (right to buy)	A - Award	D	21,14		12 039		12 039
2012-05-24	2012-05-22	4	HUGIN ROBERT J	MDCO	Common Stock	A - Award	D			5 086			44 333
2012-05-24	2012-05-22	4	Savage Robert G.	MDCO	Option (right to buy)	A - Award	D	21,14		12 039		12 039
2012-05-24	2012-05-22	4	Savage Robert G.	MDCO	Common Stock	A - Award	D			5 086			26 000
2012-05-24	2012-05-22	4	Spigelman Melvin K	MDCO	Option (right to buy)	A - Award	D	21,14		12 039		12 039
2012-05-24	2012-05-22	4	Spigelman Melvin K	MDCO	Common Stock	A - Award	D			5 086			26 000
2012-05-24	2012-05-22	4	Shigeta Hiroaki	MDCO	Option (right to buy)	A - Award	D	21,14		17 039		17 039
2012-05-24	2012-05-22	4	Shigeta Hiroaki	MDCO	Common Stock	A - Award	D			5 086			18 500
2012-05-24	2012-05-22	4	Kelly John C.	MDCO	Option (right to buy)	A - Award	D	21,14		12 039		12 039
2012-05-24	2012-05-22	4	Kelly John C.	MDCO	Common Stock	A - Award	D			5 086			20 150
2012-05-03	2012-05-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		22,1600	−5 000	−111		365 300
2012-05-03	2012-05-02	4	Kelly John C.	MDCO	Common Stock	P - Purchase	D		21,9000	9 150	200		15 064
2012-04-27	2012-04-25	4	Shigeta Hiroaki	MDCO	Option (right to buy)	M - Exercise	D	8,28		−12 500		0
2012-04-27	2012-04-25	4	Shigeta Hiroaki	MDCO	Option (right to buy)	M - Exercise	D	7,51		−7 500		0
2012-04-27	2012-04-25	4	Shigeta Hiroaki	MDCO	Common Stock	S - Sale	D		21,5000	−27 500	−591		13 414
2012-04-27	2012-04-25	4	Shigeta Hiroaki	MDCO	Common Stock	M - Exercise	D		8,2800	12 500	103		40 914
2012-04-27	2012-04-25	4	Shigeta Hiroaki	MDCO	Common Stock	M - Exercise	D		7,5100	7 500	56		28 414
2012-04-18	2012-04-16	4	Antinori Paul Michael	MDCO	Option (right to buy)	M - Exercise	D	9,13		−18 750		0
2012-04-18	2012-04-16	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		9,1300	18 750	171		62 157
2012-04-04	2012-04-02	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		20,0700	−5 000	−100		370 300
2012-03-21	2012-03-19	4	SBLENDORIO GLENN	MDCO	Option (right to buy)	M - Exercise	D	7,31		−625		15 625
2012-03-21	2012-03-19	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		20,3900	−625	−13		105 866
2012-03-21	2012-03-19	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		7,3100	625	5		106 491
2012-03-15	2012-03-14	4	KESSLER ARMIN M	MDCO	Option (right to buy)	M - Exercise	D	8,51		−7 500		0
2012-03-15	2012-03-14	4	KESSLER ARMIN M	MDCO	Common Stock	M - Exercise	D		8,5100	7 500	64		117 099
2012-03-15	2012-03-14	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		21,0800	−1 040	−22		21 933
2012-03-05	2012-03-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		21,4900	−5 000	−107		375 300
2012-03-05	2012-03-01	4	MEANWELL CLIVE	MDCO	Common Stock	J - Other	D		12,0300	883	11		380 300
2012-03-05	2012-03-01	4	SBLENDORIO GLENN	MDCO	Common Stock	J - Other	D		12,0300	883	11		105 866
2012-03-05	2012-03-01	4	Antinori Paul Michael	MDCO	Common Stock	J - Other	D		12,0300	314	4		43 407
2012-02-28	2012-02-24	4	MEANWELL CLIVE	MDCO	Option (right to buy)	A - Award	D	22,04	22,0400	150 000	3 306	150 000
2012-02-28	2012-02-24	4	MEANWELL CLIVE	MDCO	Common Stock	A - Award	D		22,0400	93 750	2 066		379 417
2012-02-28	2012-02-24	4	SBLENDORIO GLENN	MDCO	Option (right to buy)	A - Award	D	22,04	22,0400	68 000	1 499	68 000
2012-02-28	2012-02-24	4	SBLENDORIO GLENN	MDCO	Common Stock	A - Award	D		22,0400	42 500	937		104 983
2012-02-28	2012-02-24	4	Antinori Paul Michael	MDCO	Option (right to buy)	A - Award	D	22,04	22,0400	20 000	441	20 000
2012-02-28	2012-02-24	4	Antinori Paul Michael	MDCO	Common Stock	A - Award	D		22,0400	12 500	276		43 093
2012-02-28	2012-02-24	4	O'Connor William Bernard	MDCO	Option (right to buy)	A - Award	D	22,04	22,0400	20 000	441	20 000
2012-02-28	2012-02-24	4	O'Connor William Bernard	MDCO	Common Stock	A - Award	D		22,0400	12 500	276		22 973
2012-02-27	2012-02-23	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		22,2200	−1 908	−42		10 473
2012-02-23	2012-02-21	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		20,9400	−7 063	−148		285 667
2012-02-23	2012-02-21	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		20,9400	−1 842	−39		292 730
2012-02-23	2012-02-21	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		20,9400	−4 425	−93		294 572
2012-02-23	2012-02-21	4	SBLENDORIO GLENN	MDCO	Option(right to buy)	M - Exercise	D	7,31	7,3100	−625	−5	16 250
2012-02-23	2012-02-21	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		21,0300	−625	−13		62 483
2012-02-23	2012-02-21	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		7,3100	625	5		63 108
2012-02-23	2012-02-21	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		20,9400	−1 781	−37		62 483
2012-02-23	2012-02-21	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		20,9400	−833	−17		64 264
2012-02-23	2012-02-21	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		20,9400	−1 505	−32		65 097
2012-02-23	2012-02-21	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		20,9400	−1 008	−21		30 593
2012-02-23	2012-02-21	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		20,9400	−348	−7		31 601
2012-02-23	2012-02-21	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		20,9400	−223	−5		31 949
2012-02-23	2012-02-21	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		20,9400	−519	−11		12 381
2012-02-23	2012-02-21	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		20,9400	−548	−11		12 900
2012-02-23	2012-02-21	4	O'Connor William Bernard	MDCO	Common Stock	S - Sale	D		20,9400	−627	−13		13 448
2012-02-23	2012-02-21	4	Rohrbacker Leslie C	MDCO	Common Stock	S - Sale	D		20,9400	−335	−7		13 628
2012-02-23	2012-02-21	4	Rohrbacker Leslie C	MDCO	Common Stock	S - Sale	D		20,9400	−548	−11		13 963
2012-02-23	2012-02-21	4	Rohrbacker Leslie C	MDCO	Common Stock	S - Sale	D		20,9400	−627	−13		14 511
2012-02-16	2012-02-14	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		20,8900	−500	−10		32 172
2012-02-07	2012-02-03	4	Antinori Paul Michael	MDCO	Option (right to buy)	M - Exercise	D	9,13	9,1300	−5 000	−46	18 750
2012-02-07	2012-02-03	4	Antinori Paul Michael	MDCO	Common Stock	S - Sale	D		22,0000	−5 000	−110		32 672
2012-02-07	2012-02-03	4	Antinori Paul Michael	MDCO	Common Stock	M - Exercise	D		9,1300	5 000	46		37 672
2012-02-02	2012-02-01	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		20,0800	−5 000	−100		298 997
2012-02-02	2012-01-31	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		20,0000	−2 500	−50		303 997
2012-01-20	2012-01-19	4	SBLENDORIO GLENN	MDCO	Option (right to buy)	M - Exercise	D	7,31	7,3100	−625	−5	16 875
2012-01-20	2012-01-19	4	SBLENDORIO GLENN	MDCO	Common Stock	S - Sale	D		19,3800	−625	−12		66 602
2012-01-20	2012-01-19	4	SBLENDORIO GLENN	MDCO	Common Stock	M - Exercise	D		7,3100	625	5		67 227
2012-01-05	2012-01-03	4	MEANWELL CLIVE	MDCO	Common Stock	S - Sale	D		18,9900	−2 500	−47		306 497

Köp på öppna marknaden eller privat köp av icke-derivatsäkerhet

Köp på öppna marknaden eller privat försäljning av icke-derivatsäkerhet

Bevilja, tilldelning eller annat förvärv av värdepapper från företaget (såsom en option)

Omvandling av derivat

Försäljning eller överföring av värdepapper tillbaka til företaget

Betalning av lösenpris eller skatteskuld med del av värdepapper som erhållits från bolaget

Överlåtelse av värdepapper från eller till insidern

Aktieswappar och liknande säkringsaffärer

Utövande eller omvandling av derivatsäkerhet som erhållits från företaget (som en option)

En transaktion friviligt rapporterad på schema 4

Andra (med en fotnot som beskriver transaktionen)

MDCO / Medicines Company - Insider Trading and Ownership Report - SEC Form 3, 4, 5