| Insideraktier | 7 853 804 shares |
Insider Sentiment Score
Insider sentiment score hittar de företag som köps av foretagsinsynspersoner.
Det är resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av insiderackumulation. Poängmodellen använder en kombination av nettoantalet insiders som köpt de föregående 90 dagarna, det totala antalet aktier som köpts i procent av aktiekapitalet och det totala antalet aktier som ägs av insiders. Siffran sträcker sig från 0 till 100, med högre siffror som indikerar en högre nivå av ackumulering för sina kamrater, och 50 är genomsnittet.
Uppdateringsfrekvens: Dagligen
Se Insiders Top Picks, som ger en lista över företag med högsta insiderackumulation.
Office Sentiment Score
Officersentiment Score hittar företag som köps av Corporate Officers.
Per definition Corporate Officers är Corporate Insiders, men till skillnad från vissa av de andra Insiders (10 % aktieägare och styrelseledamöter), arbetar ämbetsmän för företaget dagligen och de använder sina egna pengar när de handlar . (10 % aktieägare och styrelseledamöter är ofta fondförvaltare som förvaltar andras pengar.) Som sådan är insideraffärer som görs av tjänstemän mycket mer betydelsefulla och bör behandlas på lämpligt sätt.
Liksom Insider Sentiment Score är Officer Sentiment Score resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av officersackumulering.
Uppdateringsfrekvens: Dagligen
Se insiderns bästa val, vilket ger en lista över företag med högsta insider sentiment.
Viktiga insidernyckeltal
Denna kort visar hur företaget rankas längs olika insidernyckeltal. Procenttilrankningen visar hur detta företag jämförs med andra företag på USA-marknaden. Högre rankingar indikerar bättre situationer.
Till exempel anses det allmänt att insiderköp är en positiv indikator, så företag med mer insiderköp skulle rankas högre än företag med mindre insiderköp (eller til och med insiderförsäljning).
Nettoantalet insiders som köper (rankning)
N/A
Nettoantalet insiders som köper är den totala mängden insiders som säljer minus det totala antalet insiders som säljer under de senaste 90 dagarna. Percentilrankningen visas här (intervall från 0 till 100%).
Procent av flytande köpta av insiders (ranking)
N/A
Procentandelen av aktier köpta av insiders är det totala antalet aktier som köpts av insiders minus det totala antalet aktier som sålts av insiders under de senaste 90 dagarna, dividerat med det totala antalet aktier och multiplicerat med 100.
Insiderhandelsdiagram
Concert Pharmaceuticals Inc insideraffärer visas i följande diagram. Insiders är tjänstemän, styrelseledamöter eller betydande investerare i ett företag. I allmänhet är det i allmänhet olagligt för insiders att göra affärer i sina företag baserat på väsentlig, icke-offentlig information. Detta betyder inte att det är olagligt för dem att göra några affärer i sina egna företag. De måste dock rapportera alla affärer till SEC via ett formulär 4.
Insiderlista och lönsamhetsstatistik
Den här tabellen visar listan över kända insiders och genereras automatiskt från anmälningar som avslöjas till SEC. Förutom namnen, den senaste titeln och direktören, tjänstemannen eller ägarbeteckningen på 10 %, tillhandahåller vi de senaste avslöjade innehaven. Dessutom, när det är möjligt tillhandahåller vi insiderns historiska handelsresultat. Det historiska handelsresultatet är ett vägt genomsnitt av resultatet för faktiska köptransaktioner på den öppna marknaden som insidern gjort. För mer information om hur detta beräknas, titta på detta YouTube-webinarium.
See our leaderboard of most profitable insider traders.
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|
Report errors via our new Insider Auditing Tool
Track Records av insiderköp - Kortsiktig vinstanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i CNCE / Concert Pharmaceuticals Inc. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste köpen på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Track Records av insiderförsäljning - Kortsiktig förlustanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i CNCE / Concert Pharmaceuticals Inc. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste försäljningarna på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Transaktionshistorik
Klicka på länkikonen för att se hela transaktionshistoriken. Transaktioner som rapporteras som en del av en automatisk handelsplan 10b5-1 kommer att ha ett X i kolumnen markerad 10b-5.
| Fil datum |
Handel datum |
Schema | Insider | Ticker | Värdepappertitel | Kod | Direkta | Utövningspris | Enhet pris |
Enheter ändrad |
Värde ändrad (1K) |
Kvarvarande Optioner |
Kvarvarande Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-03-06 | 2023-03-06 | 4 | van Heek Christi | CNCE | Common Stock | D | −16 400 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | van Heek Christi | CNCE | Common Stock | D | −25 651 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | −49 699 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | −38 350 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Stuart Nancy | CNCE | Common Stock | D | −73 233 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Stuart Nancy | CNCE | Common Stock | D | −167 963 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Tung Roger D By RD Tung Irrevocable Trust | CNCE | Common Stock | I | −12 389 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Tung Roger D By Tung Family Investment Trust | CNCE | Common Stock | I | −13 274 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Tung Roger D By Roger D. Tung 2011 GRAT | CNCE | Common Stock | I | −121 873 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Tung Roger D | CNCE | Common Stock | D | −57 916 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Tung Roger D | CNCE | Common Stock | D | −756 427 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Hoiland Jesper | CNCE | Common Stock | D | −16 400 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Hoiland Jesper | CNCE | Common Stock | D | −5 125 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | −16 400 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | −13 088 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | JAEGER WILFRED E | CNCE | Common Stock | D | −16 400 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | JAEGER WILFRED E | CNCE | Common Stock | D | −5 125 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Becker Marc A. | CNCE | Common Stock | D | −49 699 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Becker Marc A. | CNCE | Common Stock | D | −56 264 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Cassella James V | CNCE | Common Stock | D | −57 766 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Cassella James V | CNCE | Common Stock | D | −80 595 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Auchincloss Thomas G | CNCE | Common Stock | D | −16 400 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | Auchincloss Thomas G | CNCE | Common Stock | D | −17 625 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | ALDRICH RICHARD By Little Eagles, LLC | CNCE | Common Stock | I | −44 351 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | ALDRICH RICHARD By Richard H. Aldrich 2018 Revocable Trust | CNCE | Common Stock | I | −210 526 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | −16 400 | 0 | ||||||
| 2023-03-06 | 2023-03-06 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | −342 100 | 0 | ||||||
| 2023-02-16 | 2023-02-15 | 4 | Stuart Nancy | CNCE | Common Stock | D | 8,3300 | −6 048 | −50 | 262 596 | ||||
| 2023-02-16 | 2023-02-15 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | 8,3400 | −3 762 | −31 | 88 049 | ||||
| 2023-02-16 | 2023-02-15 | 4 | Cassella James V | CNCE | Common Stock | D | 8,3400 | −3 762 | −31 | 173 061 | ||||
| 2023-02-16 | 2023-02-15 | 4 | Becker Marc A. | CNCE | Common Stock | D | 8,3300 | −3 762 | −31 | 123 863 | ||||
| 2023-01-31 | 2023-01-30 | 4 | Stuart Nancy | CNCE | Common Stock | D | 8,3500 | −13 200 | −110 | 268 644 | ||||
| 2023-01-31 | 2023-01-30 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | 8,3500 | −8 493 | −71 | 91 811 | ||||
| 2023-01-31 | 2023-01-30 | 4 | Cassella James V | CNCE | Common Stock | D | 8,3500 | −10 106 | −84 | 176 823 | ||||
| 2023-01-31 | 2023-01-30 | 4 | Becker Marc A. | CNCE | Common Stock | D | 8,3500 | −8 493 | −71 | 127 625 | ||||
| 2023-01-09 | 2023-01-06 | 4 | Tung Roger D | CNCE | Common Stock | D | 7,2400 | −9 240 | −67 | 971 018 | ||||
| 2023-01-09 | 2023-01-06 | 4 | Stuart Nancy | CNCE | Common Stock | D | 7,2500 | −2 893 | −21 | 281 844 | ||||
| 2023-01-09 | 2023-01-06 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | 7,2500 | −2 893 | −21 | 100 304 | ||||
| 2023-01-09 | 2023-01-06 | 4 | Cassella James V | CNCE | Common Stock | D | 7,2500 | −2 893 | −21 | 186 929 | ||||
| 2023-01-09 | 2023-01-06 | 4 | Becker Marc A. | CNCE | Common Stock | D | 7,2500 | −2 893 | −21 | 136 118 | ||||
| 2022-10-18 | 2022-10-14 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | 6,0900 | −3 539 | −22 | 29 488 | ||||
| 2022-10-18 | 2022-10-14 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | 2,8800 | 3 539 | 10 | 33 027 | ||||
| 2022-06-13 | 2022-06-09 | 4 | van Heek Christi | CNCE | Common Stock | D | 16 400 | 42 051 | ||||||
| 2022-06-13 | 2022-06-09 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | 16 400 | 29 488 | ||||||
| 2022-06-13 | 2022-06-09 | 4 | JAEGER WILFRED E | CNCE | Common Stock | D | 16 400 | 21 525 | ||||||
| 2022-06-13 | 2022-06-09 | 4 | Hoiland Jesper | CNCE | Common Stock | D | 16 400 | 21 525 | ||||||
| 2022-06-13 | 2022-06-09 | 4 | Auchincloss Thomas G | CNCE | Common Stock | D | 16 400 | 34 025 | ||||||
| 2022-06-13 | 2022-06-09 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 16 400 | 358 500 | ||||||
| 2022-06-06 | 2022-06-06 | 4 | van Heek Christi | CNCE | Common Stock | D | 4,7500 | 10 526 | 50 | 25 651 | ||||
| 2022-06-06 | 2022-06-06 | 4 | Auchincloss Thomas G | CNCE | Common Stock | D | 4,7500 | 6 000 | 28 | 17 625 | ||||
| 2022-06-06 | 2022-06-06 | 4 | ALDRICH RICHARD By Richard H. Aldrich 2018 Revocable Trust | CNCE | Common Stock | I | 4,7500 | 210 526 | 1 000 | 210 526 | ||||
| 2022-02-16 | 2022-02-15 | 4 | Tung Roger D | CNCE | Common Stock | D | 3,0900 | −13 480 | −42 | 980 258 | ||||
| 2022-02-16 | 2022-02-14 | 4 | Stuart Nancy | CNCE | Common Stock | D | 3,0800 | −6 049 | −19 | 284 737 | ||||
| 2022-02-16 | 2022-02-14 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | 3,0900 | −3 762 | −12 | 103 197 | ||||
| 2022-02-16 | 2022-02-14 | 4 | Cassella James V | CNCE | Common Stock | D | 3,0900 | −3 762 | −12 | 189 822 | ||||
| 2022-02-16 | 2022-02-14 | 4 | Becker Marc A. | CNCE | Common Stock | D | 3,0800 | −3 762 | −12 | 139 011 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Stuart Nancy | CNCE | Common Stock | D | 21 400 | 290 786 | ||||||
| 2022-02-01 | 2022-01-28 | 4 | Stuart Nancy | CNCE | Common Stock | D | 99 000 | 269 386 | ||||||
| 2022-02-01 | 2022-01-28 | 4 | Tung Roger D | CNCE | Common Stock | D | 156 675 | 993 738 | ||||||
| 2022-02-01 | 2022-01-28 | 4 | Tung Roger D | CNCE | Common Stock | D | 52 225 | 837 063 | ||||||
| 2022-02-01 | 2022-01-28 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | 63 700 | 106 959 | ||||||
| 2022-02-01 | 2022-01-28 | 4 | Becker Marc A. | CNCE | Common Stock | D | 17 900 | 142 773 | ||||||
| 2022-02-01 | 2022-01-28 | 4 | Becker Marc A. | CNCE | Common Stock | D | 63 700 | 124 873 | ||||||
| 2022-02-01 | 2022-01-28 | 4 | Cassella James V | CNCE | Common Stock | D | 34 700 | 193 584 | ||||||
| 2022-02-01 | 2022-01-28 | 4 | Cassella James V | CNCE | Common Stock | D | 75 800 | 158 884 | ||||||
| 2022-01-07 | 2022-01-06 | 4 | Tung Roger D | CNCE | Common Stock | D | 3,0900 | −9 240 | −29 | 784 838 | ||||
| 2022-01-07 | 2021-12-15 | 4 | Tung Roger D | CNCE | Common Stock | D | −7 500 | 794 078 | ||||||
| 2022-01-07 | 2021-12-14 | 4 | Tung Roger D | CNCE | Common Stock | D | −7 000 | 801 578 | ||||||
| 2022-01-07 | 2022-01-05 | 4 | Stuart Nancy | CNCE | Common Stock | D | 3,1900 | −2 894 | −9 | 170 386 | ||||
| 2022-01-07 | 2022-01-05 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | 3,2000 | −2 894 | −9 | 43 259 | ||||
| 2022-01-07 | 2022-01-05 | 4 | Cassella James V | CNCE | Common Stock | D | 3,1900 | −2 894 | −9 | 83 084 | ||||
| 2022-01-07 | 2022-01-05 | 4 | Becker Marc A. | CNCE | Common Stock | D | 3,2000 | −2 894 | −9 | 61 173 | ||||
| 2021-12-15 | 2021-12-13 | 4 | Tung Roger D | CNCE | Stock Option (right to buy) | D | 3,50 | −6 700 | 4 522 | |||||
| 2021-12-15 | 2021-12-13 | 4 | Tung Roger D | CNCE | Common Stock | D | 3,6200 | −6 700 | −24 | 808 578 | ||||
| 2021-12-15 | 2021-12-13 | 4 | Tung Roger D | CNCE | Common Stock | D | 3,5000 | 6 700 | 23 | 815 278 | ||||
| 2021-08-17 | 2021-08-16 | 4 | Becker Marc A. | CNCE | Common Stock | D | 3,2800 | −7 304 | −24 | 64 067 | ||||
| 2021-08-17 | 2021-08-16 | 4 | Cassella James V | CNCE | Common Stock | D | 3,2800 | −8 086 | −27 | 85 978 | ||||
| 2021-06-11 | 2021-06-10 | 4 | van Heek Christi | CNCE | Stock Option (right to buy) | D | 4,26 | 10 250 | 10 250 | |||||
| 2021-06-11 | 2021-06-10 | 4 | van Heek Christi | CNCE | Common Stock | D | 5 125 | 15 125 | ||||||
| 2021-06-11 | 2021-06-10 | 4 | JAEGER WILFRED E | CNCE | Stock Option (right to buy) | D | 4,26 | 10 250 | 10 250 | |||||
| 2021-06-11 | 2021-06-10 | 4 | JAEGER WILFRED E | CNCE | Common Stock | D | 5 125 | 5 125 | ||||||
| 2021-06-11 | 2021-06-10 | 4 | HUTT PETER BARTON | CNCE | Stock Option (right to buy) | D | 4,26 | 10 250 | 10 250 | |||||
| 2021-06-11 | 2021-06-10 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | 5 125 | 13 088 | ||||||
| 2021-06-11 | 2021-06-10 | 4 | Hoiland Jesper | CNCE | Stock Option (right to buy) | D | 4,26 | 10 250 | 10 250 | |||||
| 2021-06-11 | 2021-06-10 | 4 | Hoiland Jesper | CNCE | Common Stock | D | 5 125 | 5 125 | ||||||
| 2021-06-11 | 2021-06-10 | 4 | Barrett Ronald W | CNCE | Stock Option (right to buy) | D | 4,26 | 10 250 | 10 250 | |||||
| 2021-06-11 | 2021-06-10 | 4 | Barrett Ronald W | CNCE | Common Stock | D | 5 125 | 5 125 | ||||||
| 2021-06-11 | 2021-06-10 | 4 | Auchincloss Thomas G | CNCE | Stock Option (right to buy) | D | 4,26 | 10 250 | 10 250 | |||||
| 2021-06-11 | 2021-06-10 | 4 | Auchincloss Thomas G | CNCE | Common Stock | D | 5 125 | 11 625 | ||||||
| 2021-06-11 | 2021-06-10 | 4 | ALDRICH RICHARD | CNCE | Stock Option (right to buy) | D | 4,26 | 30 182 | 30 182 | |||||
| 2021-06-11 | 2021-06-10 | 4 | ALDRICH RICHARD | CNCE | Stock Option (right to buy) | D | 4,26 | 10 250 | 10 250 | |||||
| 2021-06-11 | 2021-06-10 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 5 125 | 342 100 | ||||||
| 2021-02-17 | 2021-02-17 | 4 | Tung Roger D | CNCE | Common Stock | D | 7,2000 | −13 480 | −97 | 808 578 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Stuart Nancy | CNCE | Common Stock | D | 7,3200 | −6 049 | −44 | 173 280 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | 7,3200 | −3 763 | −28 | 46 153 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Cassella James V | CNCE | Common Stock | D | 7,3200 | −3 763 | −28 | 94 064 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Becker Marc A. | CNCE | Common Stock | D | 7,3200 | −3 763 | −28 | 71 371 | ||||
| 2021-01-07 | 2021-01-05 | 4 | Tung Roger D | CNCE | Stock Option (Right to Buy) | D | 13,07 | 205 000 | 205 000 | |||||
| 2021-01-07 | 2021-01-05 | 4 | Tung Roger D | CNCE | Common Stock | D | 69 300 | 822 058 | ||||||
| 2021-01-07 | 2021-01-05 | 4 | Stuart Nancy | CNCE | Stock Option (Right to Buy) | D | 13,07 | 51 850 | 51 850 | |||||
| 2021-01-07 | 2021-01-05 | 4 | Stuart Nancy | CNCE | Common Stock | D | 21 700 | 179 329 | ||||||
| 2021-01-07 | 2021-01-05 | 4 | Munsie Jeffrey A | CNCE | Stock Option (Right to Buy) | D | 13,07 | 51 850 | 51 850 | |||||
| 2021-01-07 | 2021-01-05 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | 21 700 | 49 916 | ||||||
| 2021-01-07 | 2021-01-05 | 4 | Cassella James V | CNCE | Stock Option (Right to Buy) | D | 13,07 | 60 400 | 60 400 | |||||
| 2021-01-07 | 2021-01-05 | 4 | Cassella James V | CNCE | Common Stock | D | 21 700 | 97 827 | ||||||
| 2021-01-07 | 2021-01-05 | 4 | Becker Marc A. | CNCE | Stock Option (Right to Buy) | D | 13,07 | 51 850 | 51 850 | |||||
| 2021-01-07 | 2021-01-05 | 4 | Becker Marc A. | CNCE | Common Stock | D | 21 700 | 75 134 | ||||||
| 2020-09-01 | 2020-08-31 | 4 | HUTT PETER BARTON | CNCE | Stock Option (right to buy) | D | 3,79 | −3 539 | 0 | |||||
| 2020-09-01 | 2020-08-31 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | 3,7900 | 3 539 | 13 | 7 963 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Cassella James V | CNCE | Common Stock | D | 10,3700 | −4 354 | −45 | 76 127 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Becker Marc A. | CNCE | Common Stock | D | 10,2400 | −2 875 | −29 | 53 434 | ||||
| 2020-06-24 | 2020-06-22 | 4 | Stuart Nancy | CNCE | Stock Option (right to buy) | D | 3,79 | −21 238 | 0 | |||||
| 2020-06-24 | 2020-06-22 | 4 | Stuart Nancy | CNCE | Common Stock | D | 11,3350 | −10 295 | −117 | 157 629 | ||||
| 2020-06-24 | 2020-06-22 | 4 | Stuart Nancy | CNCE | Common Stock | D | 3,7900 | 21 238 | 80 | 167 924 | ||||
| 2020-06-12 | 2020-06-11 | 4 | ALDRICH RICHARD | CNCE | Stock Option (right to buy) | D | 9,16 | 13 260 | 13 260 | |||||
| 2020-06-12 | 2020-06-11 | 4 | ALDRICH RICHARD | CNCE | Stock Option (right to buy) | D | 9,16 | 10 000 | 10 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | Auchincloss Thomas G | CNCE | Stock Option (right to buy) | D | 9,16 | 10 000 | 10 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | Barrett Ronald W | CNCE | Stock Option (right to buy) | D | 9,16 | 10 000 | 10 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | Hoiland Jesper | CNCE | Stock Option (right to buy) | D | 9,16 | 10 000 | 10 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | HUTT PETER BARTON | CNCE | Stock Option (right to buy) | D | 9,16 | 10 000 | 10 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | JAEGER WILFRED E | CNCE | Stock Option (right to buy) | D | 9,16 | 10 000 | 10 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | van Heek Christi | CNCE | Stock Option (right to buy) | D | 9,16 | 4 144 | 4 144 | |||||
| 2020-06-12 | 2020-06-11 | 4 | van Heek Christi | CNCE | Stock Option (right to buy) | D | 9,16 | 10 000 | 10 000 | |||||
| 2020-03-16 | 2020-03-13 | 4 | Tung Roger D | CNCE | Stock Option (right to buy) | D | 3,79 | −14 601 | 0 | |||||
| 2020-03-16 | 2020-03-13 | 4 | Tung Roger D | CNCE | Common Stock | D | 3,7900 | 14 601 | 55 | 752 758 | ||||
| 2020-03-13 | 2020-03-12 | 4 | Auchincloss Thomas G | CNCE | Common Stock | D | 8,5150 | 1 500 | 13 | 6 500 | ||||
| 2020-02-19 | 2020-02-14 | 4 | Munsie Jeffrey A | CNCE | Stock Option (Right to Buy) | D | 10,87 | 42 430 | 42 430 | |||||
| 2020-02-19 | 2020-02-14 | 4 | Munsie Jeffrey A | CNCE | Common Stock | D | 28 216 | 28 216 | ||||||
| 2020-02-19 | 2020-02-14 | 4 | Becker Marc A. | CNCE | Stock Option (Right to Buy) | D | 10,87 | 42 430 | 42 430 | |||||
| 2020-02-19 | 2020-02-14 | 4 | Becker Marc A. | CNCE | Common Stock | D | 28 216 | 56 309 | ||||||
| 2020-02-19 | 2020-02-14 | 4 | Cassella James V | CNCE | Stock Option (Right to Buy) | D | 10,87 | 42 430 | 42 430 | |||||
| 2020-02-19 | 2020-02-14 | 4 | Cassella James V | CNCE | Common Stock | D | 28 216 | 80 481 | ||||||
| 2020-02-19 | 2020-02-14 | 4 | Stuart Nancy | CNCE | Stock Option (Right to Buy) | D | 10,87 | 68 215 | 68 215 | |||||
| 2020-02-19 | 2020-02-14 | 4 | Stuart Nancy | CNCE | Common Stock | D | 45 363 | 146 686 | ||||||
| 2020-02-19 | 2020-02-14 | 4 | Tung Roger D | CNCE | Stock Option (Right to Buy) | D | 10,87 | 151 600 | 151 600 | |||||
| 2020-02-19 | 2020-02-14 | 4 | Tung Roger D | CNCE | Common Stock | D | 101 100 | 738 157 | ||||||
| 2020-02-04 | 2020-02-03 | 4 | Auchincloss Thomas G | CNCE | Common Stock | D | 10,9100 | 1 000 | 11 | 5 000 | ||||
| 2019-12-06 | 2019-12-04 | 4 | Tung Roger D | CNCE | Employee Stock Option (Right to Buy) | D | 4,41 | −13 166 | 0 | |||||
| 2019-12-06 | 2019-12-04 | 4 | Tung Roger D | CNCE | Common Stock | D | 7,6100 | −7 629 | −58 | 637 057 | ||||
| 2019-12-06 | 2019-12-04 | 4 | Tung Roger D | CNCE | Common Stock | D | 4,4100 | 13 166 | 58 | 644 686 | ||||
| 2019-12-06 | 2019-12-04 | 4 | Stuart Nancy | CNCE | Employee Stock Option (Right to Buy) | D | 4,41 | −5 896 | 0 | |||||
| 2019-12-06 | 2019-12-04 | 4 | Stuart Nancy | CNCE | Common Stock | D | 7,6100 | −3 416 | −26 | 101 323 | ||||
| 2019-12-06 | 2019-12-04 | 4 | Stuart Nancy | CNCE | Common Stock | D | 4,4100 | 5 896 | 26 | 104 739 | ||||
| 2019-10-10 | 2019-10-08 | 4 | van Heek Christi | CNCE | Common Stock | D | 5,9007 | 5 000 | 30 | 10 000 | ||||
| 2019-10-10 | 2019-08-02 | 4 | van Heek Christi | CNCE | Common Stock | D | 10,8406 | 5 000 | 54 | 5 000 | ||||
| 2019-09-27 | 2019-09-26 | 4 | Munsie Jeffrey A | CNCE | Employee Stock Option (Right to Buy) | D | 9,87 | 100 000 | 100 000 | |||||
| 2019-08-19 | 2019-08-15 | 4 | Cassella James V | CNCE | Common Stock | D | 31 100 | 52 265 | ||||||
| 2019-08-19 | 2019-08-15 | 4 | Becker Marc A. | CNCE | Common Stock | D | 28 093 | 28 093 | ||||||
| 2019-08-19 | 2019-08-15 | 4 | Lynch Ryan | CNCE | Common Stock | D | 14 063 | 18 059 | ||||||
| 2019-08-12 | 2019-08-08 | 4 | HUTT PETER BARTON | CNCE | Non-qualified Stock Option (right to buy) | D | 4,41 | −3 539 | 0 | |||||
| 2019-08-12 | 2019-08-08 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | 10,3100 | −3 539 | −36 | 4 424 | ||||
| 2019-08-12 | 2019-08-08 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | 4,4100 | 3 539 | 16 | 7 963 | ||||
| 2019-06-17 | 2019-06-13 | 4 | Barrett Ronald W | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 11,02 | 10 000 | 10 000 | |||||
| 2019-06-17 | 2019-06-13 | 4 | HUTT PETER BARTON | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 11,02 | 10 000 | 10 000 | |||||
| 2019-06-17 | 2019-06-13 | 4 | JAEGER WILFRED E | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 11,02 | 10 000 | 10 000 | |||||
| 2019-06-17 | 2019-06-13 | 4 | ALDRICH RICHARD | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 11,02 | 10 000 | 10 000 | |||||
| 2019-06-17 | 2019-06-13 | 4 | Hoiland Jesper | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 11,02 | 25 000 | 25 000 | |||||
| 2019-06-17 | 2019-06-13 | 4 | van Heek Christi | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 11,02 | 10 000 | 10 000 | |||||
| 2019-06-17 | 2019-06-13 | 4 | Auchincloss Thomas G | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 11,02 | 10 000 | 10 000 | |||||
| 2019-06-12 | 2019-06-10 | 4 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value | D | 10,7039 | −29 450 | −315 | 169 589 | ||||
| 2019-06-12 | 2019-06-10 | 4 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value | D | 10,7039 | −158 583 | −1 697 | 952 859 | ||||
| 2019-06-12 | 2019-06-10 | 4 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value | D | 10,7039 | −198 256 | −2 122 | 1 178 904 | ||||
| 2019-04-24 | 2019-04-23 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 3,79 | −14 601 | 14 601 | |||||
| 2019-04-24 | 2019-04-23 | 4 | Tung Roger D | CNCE | Common Stock | D | 3,7900 | 14 601 | 55 | 631 520 | ||||
| 2019-04-10 | 2019-04-10 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 4,41 | −24 886 | 13 166 | |||||
| 2019-04-10 | 2019-04-10 | 4 | Tung Roger D | CNCE | Common Stock | D | 4,4100 | 24 886 | 110 | 616 919 | ||||
| 2019-04-02 | 2019-03-31 | 4 | Stuart Nancy | CNCE | Common Stock | D | 12,0700 | −8 835 | −107 | 98 843 | ||||
| 2019-04-02 | 2019-03-31 | 4 | Cassella James V | CNCE | Common Stock | D | 12,0700 | −8 835 | −107 | 21 165 | ||||
| 2019-04-02 | 2019-03-31 | 4 | Lynch Ryan | CNCE | Common Stock | D | 12,0700 | −1 043 | −13 | 3 996 | ||||
| 2019-04-02 | 2019-03-31 | 4 | Tung Roger D | CNCE | Common Stock | D | 12,0700 | −5 890 | −71 | 592 033 | ||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 2 886 680 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 3 799 083 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 2 886 680 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 4 064 801 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 3 799 083 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 2 886 680 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 4 064 801 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 3 799 083 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 2 886 680 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 4 064 801 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 3 799 083 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 2 886 680 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 4 064 801 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 3 799 083 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 4 064 801 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 3 799 083 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 2 886 680 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 4 064 801 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 3 799 083 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 2 886 680 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 4 064 801 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 3 799 083 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 2 886 680 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 4 064 801 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 3 799 083 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 2 886 680 | ||||||||
| 2019-04-02 | 3 | LAMPERT MARK N | CNCE | Common Stock, $0.001 par value | D | 4 064 801 | ||||||||
| 2019-02-07 | 2019-02-06 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 4,41 | −28 616 | 5 896 | |||||
| 2019-02-07 | 2019-02-06 | 4 | Stuart Nancy | CNCE | Common Stock | D | 13,9500 | −9 046 | −126 | 107 678 | ||||
| 2019-02-07 | 2019-02-06 | 4 | Stuart Nancy | CNCE | Common Stock | D | 4,4100 | 28 616 | 126 | 116 724 | ||||
| 2019-01-08 | 2019-01-04 | 4 | Cassella James V | CNCE | Employee Stock Option (right to buy) | D | 13,93 | 75 000 | 75 000 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Becker Marc A. | CNCE | Employee Stock Option (right to buy) | D | 13,93 | 110 000 | 110 000 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 13,93 | 200 000 | 200 000 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 13,93 | 75 000 | 75 000 | |||||
| 2019-01-08 | 2019-01-04 | 4 | Lynch Ryan | CNCE | Employee Stock Option (right to buy) | D | 13,93 | 6 100 | 6 100 | |||||
| 2018-11-30 | 2018-11-29 | 4 | Stuart Nancy | CNCE | Common Stock | D | −1 850 | 88 108 | ||||||
| 2018-11-19 | 2018-11-15 | 4 | Auchincloss Thomas G | CNCE | Common Stock | D | 11,5000 | 1 000 | 12 | 4 000 | ||||
| 2018-11-15 | 2018-11-15 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 11,7817 | 40 000 | 471 | 336 975 | ||||
| 2018-11-15 | 2018-11-15 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 11,9994 | 10 000 | 120 | 296 975 | ||||
| 2018-11-15 | 2018-11-14 | 4 | Auchincloss Thomas G | CNCE | Common Stock | D | 11,9314 | 1 000 | 12 | 3 000 | ||||
| 2018-07-11 | 2018-07-10 | 4 | Stuart Nancy | CNCE | Common Stock | D | 17,9392 | −26 127 | −469 | 89 958 | ||||
| 2018-07-11 | 2018-07-09 | 4 | Stuart Nancy | CNCE | Common Stock | D | 17,5562 | −5 291 | −93 | 116 085 | ||||
| 2018-06-18 | 2018-06-14 | 4 | ALDRICH RICHARD | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 19,59 | 5 940 | 15 940 | |||||
| 2018-06-18 | 2018-06-14 | 4 | ALDRICH RICHARD | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 19,59 | 10 000 | 10 000 | |||||
| 2018-06-18 | 2018-06-14 | 4 | Auchincloss Thomas G | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 19,59 | 10 000 | 10 000 | |||||
| 2018-06-18 | 2018-06-14 | 4 | van Heek Christi | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 19,59 | 10 000 | 10 000 | |||||
| 2018-06-18 | 2018-06-14 | 4 | Barrett Ronald W | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 19,59 | 10 000 | 10 000 | |||||
| 2018-06-18 | 2018-06-14 | 4 | Fitzgerald Meghan | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 19,59 | 3 453 | 13 453 | |||||
| 2018-06-18 | 2018-06-14 | 4 | Fitzgerald Meghan | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 19,59 | 10 000 | 10 000 | |||||
| 2018-06-18 | 2018-06-14 | 4 | HUTT PETER BARTON | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 19,59 | 10 000 | 10 000 | |||||
| 2018-06-18 | 2018-06-14 | 4 | WIERENGA WENDALL | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 19,59 | 10 000 | 10 000 | |||||
| 2018-06-18 | 2018-06-14 | 4 | JAEGER WILFRED E | CNCE | Nonstatutory Stock Option (Right to Buy) | D | 19,59 | 10 000 | 10 000 | |||||
| 2018-06-12 | 2018-06-11 | 4 | Tung Roger D | CNCE | Common Stock | D | −1 000 | 597 923 | ||||||
| 2018-04-19 | 2018-04-17 | 4 | Cassella James V | CNCE | Common Stock | D | 20,1767 | −10 582 | −214 | 30 000 | ||||
| 2018-04-13 | 2018-03-31 | 4/A | Tung Roger D | CNCE | Common Stock | D | 22,9000 | −5 890 | −135 | 598 923 | ||||
| 2018-04-13 | 2018-03-31 | 4/A | Stuart Nancy | CNCE | Common Stock | D | 22,9000 | −4 418 | −101 | 121 376 | ||||
| 2018-04-13 | 2018-03-31 | 4/A | HERSCHA LYNETTE | CNCE | Common Stock | D | 22,9000 | −3 682 | −84 | 33 818 | ||||
| 2018-04-13 | 2018-03-31 | 4/A | Cassella James V | CNCE | Common Stock | D | 22,9000 | −4 418 | −101 | 40 582 | ||||
| 2018-04-03 | 2018-03-31 | 4 | HERSCHA LYNETTE | CNCE | Common Stock | D | 22,9000 | −3 682 | −84 | 46 318 | ||||
| 2018-04-03 | 2018-03-31 | 4 | Tung Roger D | CNCE | Common Stock | D | 22,9000 | −5 890 | −135 | 638 923 | ||||
| 2018-04-03 | 2018-03-31 | 4 | Cassella James V | CNCE | Common Stock | D | 22,9000 | −4 418 | −101 | 55 582 | ||||
| 2018-04-03 | 2018-03-31 | 4 | Stuart Nancy | CNCE | Common Stock | D | 22,9000 | −4 418 | −101 | 136 376 | ||||
| 2018-04-03 | 2018-03-31 | 4 | Lynch Ryan | CNCE | Common Stock | D | 22,9000 | −961 | −22 | 5 039 | ||||
| 2018-03-05 | 2018-03-02 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 4,58 | −27 757 | 0 | |||||
| 2018-03-05 | 2018-03-02 | 4 | Tung Roger D | CNCE | Common Stock | D | 21,0400 | −6 042 | −127 | 644 813 | ||||
| 2018-03-05 | 2018-03-02 | 4 | Tung Roger D | CNCE | Common Stock | D | 4,5800 | 27 757 | 127 | 650 855 | ||||
| 2018-02-01 | 2018-02-01 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,9900 | −1 946 | −39 | 0 | ||||
| 2018-02-01 | 2018-01-31 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 21,2900 | −300 | −6 | 1 946 | ||||
| 2018-02-01 | 2018-01-31 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 20,7800 | −4 700 | −98 | 2 246 | ||||
| 2018-02-01 | 2018-01-30 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 21,3300 | −5 000 | −107 | 6 946 | ||||
| 2018-01-29 | 2018-01-29 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 21,3600 | −5 000 | −107 | 11 946 | ||||
| 2018-01-29 | 2018-01-26 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 20,4600 | −5 000 | −102 | 16 946 | ||||
| 2018-01-29 | 2018-01-25 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 20,2200 | −3 054 | −62 | 44 351 | ||||
| 2018-01-29 | 2018-01-25 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 20,3100 | −5 000 | −102 | 21 946 | ||||
| 2018-01-26 | 2018-01-04 | 4/A | Becker Marc A. | CNCE | Employee Stock Option (right to buy) | D | 27,59 | 100 000 | 100 000 | |||||
| 2018-01-26 | 2018-01-25 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 4,58 | −48 882 | 0 | |||||
| 2018-01-26 | 2018-01-25 | 4 | Stuart Nancy | CNCE | Common Stock | D | 20,2300 | −11 066 | −224 | 140 794 | ||||
| 2018-01-26 | 2018-01-25 | 4 | Stuart Nancy | CNCE | Common Stock | D | 4,5800 | 48 882 | 224 | 151 860 | ||||
| 2018-01-24 | 2018-01-24 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,8300 | −5 000 | −99 | 47 405 | ||||
| 2018-01-24 | 2018-01-24 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,8300 | −5 000 | −99 | 47 405 | ||||
| 2018-01-24 | 2018-01-23 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,6800 | −5 000 | −98 | 52 405 | ||||
| 2018-01-24 | 2018-01-23 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,6700 | −5 000 | −98 | 31 946 | ||||
| 2018-01-24 | 2018-01-22 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,5400 | −5 000 | −98 | 57 405 | ||||
| 2018-01-24 | 2018-01-22 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,5500 | −5 000 | −98 | 36 946 | ||||
| 2018-01-19 | 2018-01-19 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,6500 | −5 000 | −98 | 62 405 | ||||
| 2018-01-19 | 2018-01-19 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,6600 | −5 000 | −98 | 41 946 | ||||
| 2018-01-19 | 2018-01-18 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,4300 | −5 000 | −97 | 67 405 | ||||
| 2018-01-19 | 2018-01-18 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,3600 | −5 000 | −97 | 46 946 | ||||
| 2018-01-19 | 2018-01-17 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,0300 | −5 000 | −95 | 72 405 | ||||
| 2018-01-19 | 2018-01-17 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 18,9500 | −5 000 | −95 | 51 946 | ||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Non-Qualified Stock Option (Right to Buy) | D | 2,88 | −5 309 | 0 | |||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Non-Qualified Stock Option (Right to Buy) | D | 4,41 | −5 309 | 0 | |||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Non-Qualified Stock Option (Right to Buy) | D | 3,50 | −5 309 | 0 | |||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Non-Qualified Stock Option (Right to Buy) | D | 3,79 | −5 309 | 0 | |||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,2600 | −5 000 | −96 | 77 405 | ||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 19,2700 | −5 000 | −96 | 56 946 | ||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 19,0800 | −21 236 | −405 | 286 975 | ||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 2,8800 | 5 309 | 15 | 308 211 | ||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 3,5000 | 5 309 | 19 | 302 902 | ||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 3,7900 | 5 309 | 20 | 297 593 | ||||
| 2018-01-18 | 2018-01-16 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 4,4100 | 5 309 | 23 | 292 284 | ||||
| 2018-01-08 | 2018-01-04 | 4 | Cassella James V | CNCE | Employee Stock Option (right to buy) | D | 27,59 | 49 500 | 49 500 | |||||
| 2018-01-08 | 2018-01-04 | 4 | Lynch Ryan | CNCE | Employee Stock Option (right to buy) | D | 27,59 | 4 950 | 4 950 | |||||
| 2018-01-08 | 2018-01-04 | 4 | HERSCHA LYNETTE | CNCE | Employee Stock Option (right to buy) | D | 27,59 | 49 500 | 49 500 | |||||
| 2018-01-08 | 2018-01-04 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 27,59 | 70 000 | 70 000 | |||||
| 2018-01-08 | 2018-01-04 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 27,59 | 200 000 | 200 000 | |||||
| 2018-01-08 | 2017-11-22 | 4 | Tung Roger D | CNCE | Common Stock | D | −1 600 | 623 098 | ||||||
| 2017-12-21 | 2017-12-19 | 4 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value | D | 26,6500 | −169 292 | −4 512 | 122 496 | ||||
| 2017-12-21 | 2017-12-19 | 4 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value | D | 26,6500 | −445 615 | −11 876 | 632 642 | ||||
| 2017-12-21 | 2017-12-19 | 4 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value | D | 26,6500 | −667 949 | −17 801 | 951 300 | ||||
| 2017-12-06 | 2017-12-04 | 4 | Barrett Ronald W | CNCE | Non-qualified Stock Option (right to buy) | D | 4,41 | −3 539 | 0 | |||||
| 2017-12-06 | 2017-12-04 | 4 | Barrett Ronald W | CNCE | Non-qualified Stock Option (right to buy) | D | 2,88 | −3 539 | 0 | |||||
| 2017-12-06 | 2017-12-04 | 4 | Barrett Ronald W | CNCE | Non-qualified Stock Option (right to buy) | D | 3,50 | −3 539 | 0 | |||||
| 2017-12-06 | 2017-12-04 | 4 | Barrett Ronald W | CNCE | Non-qualified Stock Option (right to buy) | D | 3,79 | −3 539 | 0 | |||||
| 2017-12-06 | 2017-12-04 | 4 | Barrett Ronald W | CNCE | Common Stock | D | 24,7000 | −14 156 | −350 | 0 | ||||
| 2017-12-06 | 2017-12-04 | 4 | Barrett Ronald W | CNCE | Common Stock | D | 2,8800 | 3 539 | 10 | 14 156 | ||||
| 2017-12-06 | 2017-12-04 | 4 | Barrett Ronald W | CNCE | Common Stock | D | 3,5000 | 3 539 | 12 | 10 617 | ||||
| 2017-12-06 | 2017-12-04 | 4 | Barrett Ronald W | CNCE | Common Stock | D | 3,7900 | 3 539 | 13 | 7 078 | ||||
| 2017-12-06 | 2017-12-04 | 4 | Barrett Ronald W | CNCE | Common Stock | D | 4,4100 | 3 539 | 16 | 3 539 | ||||
| 2017-11-20 | 2017-11-17 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 4,58 | −7 340 | 27 757 | |||||
| 2017-11-20 | 2017-11-17 | 4 | Tung Roger D | CNCE | Common Stock | D | 20,9100 | −1 607 | −34 | 624 698 | ||||
| 2017-11-20 | 2017-11-17 | 4 | Tung Roger D | CNCE | Common Stock | D | 4,5800 | 7 340 | 34 | 626 305 | ||||
| 2017-11-15 | 2017-11-15 | 4 | Stuart Nancy | CNCE | Common Stock | D | −1 100 | 102 978 | ||||||
| 2017-11-15 | 2017-11-14 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 4,58 | −4 215 | 48 882 | |||||
| 2017-11-15 | 2017-11-14 | 4 | Stuart Nancy | CNCE | Common Stock | D | 18,5700 | −1 039 | −19 | 104 078 | ||||
| 2017-11-15 | 2017-11-14 | 4 | Stuart Nancy | CNCE | Common Stock | D | 4,5800 | 4 215 | 19 | 105 117 | ||||
| 2017-10-23 | 2017-10-19 | 4 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value | D | 15,8375 | 34 632 | 548 | 291 788 | ||||
| 2017-10-23 | 2017-10-19 | 4 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value | D | 15,8375 | 135 206 | 2 141 | 1 078 257 | ||||
| 2017-10-23 | 2017-10-19 | 4 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value | D | 15,8375 | 162 078 | 2 567 | 1 619 249 | ||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 4 114 549 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 3 600 429 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 2 914 534 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 4 114 549 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 3 600 429 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 2 914 534 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 4 114 549 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 3 600 429 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 2 914 534 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 4 114 549 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 3 600 429 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 2 914 534 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 4 114 549 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 3 600 429 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 2 914 534 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 4 114 549 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 3 600 429 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 2 914 534 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 4 114 549 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 3 600 429 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 2 914 534 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 4 114 549 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 3 600 429 | ||||||||
| 2017-09-29 | 3 | BVF PARTNERS L P/IL | CNCE | Common Stock, $0.001 par value per share | D | 2 914 534 | ||||||||
| 2017-09-18 | 2017-09-14 | 4 | Lynch Ryan | CNCE | Employee Stock Option (right to buy) | D | 9,46 | −3 500 | 3 200 | |||||
| 2017-09-18 | 2017-09-14 | 4 | Lynch Ryan | CNCE | Common Stock | D | 14,5100 | −3 500 | −51 | 6 000 | ||||
| 2017-09-18 | 2017-09-14 | 4 | Lynch Ryan | CNCE | Common Stock | D | 9,4600 | 3 500 | 33 | 9 500 | ||||
| 2017-07-10 | 2017-07-06 | 4 | Cassella James V | CNCE | Common Stock | D | 60 000 | 60 000 | ||||||
| 2017-07-10 | 2017-07-06 | 4 | Stuart Nancy | CNCE | Common Stock | D | 60 000 | 100 902 | ||||||
| 2017-07-10 | 2017-07-06 | 4 | Lynch Ryan | CNCE | Common Stock | D | 6 000 | 6 000 | ||||||
| 2017-07-10 | 2017-07-06 | 4 | Tung Roger D | CNCE | Common Stock | D | 80 000 | 618 965 | ||||||
| 2017-07-10 | 2017-07-06 | 4 | HERSCHA LYNETTE | CNCE | Common Stock | D | 50 000 | 50 000 | ||||||
| 2017-06-19 | 2017-06-15 | 4 | WIERENGA WENDALL | CNCE | Nonstatutory Stock Option (right to buy) | D | 13,29 | 10 000 | 10 000 | |||||
| 2017-06-19 | 2017-06-15 | 4 | HERSCHA LYNETTE | CNCE | Employee Stock Option (right to buy) | D | 13,29 | 10 000 | 10 000 | |||||
| 2017-06-19 | 2017-06-15 | 4 | JAEGER WILFRED E | CNCE | Nonstatutory Stock Option (right to buy) | D | 13,29 | 10 000 | 10 000 | |||||
| 2017-06-19 | 2017-06-15 | 4 | van Heek Christi | CNCE | Nonstatutory Stock Option (right to buy) | D | 13,29 | 10 000 | 10 000 | |||||
| 2017-06-19 | 2017-06-15 | 4 | ALDRICH RICHARD | CNCE | Nonstatutory Stock Option (right to buy) | D | 13,29 | 10 000 | 10 000 | |||||
| 2017-06-19 | 2017-06-15 | 4 | Barrett Ronald W | CNCE | Nonstatutory Stock Option (right to buy) | D | 13,29 | 10 000 | 10 000 | |||||
| 2017-06-19 | 2017-06-15 | 4 | Fitzgerald Meghan | CNCE | Nonstatutory Stock Option (right to buy) | D | 13,29 | 10 000 | 10 000 | |||||
| 2017-06-19 | 2017-06-15 | 4 | HUTT PETER BARTON | CNCE | Nonstatutory Stock Option (right to buy) | D | 13,29 | 10 000 | 10 000 | |||||
| 2017-06-19 | 2017-06-15 | 4 | Auchincloss Thomas G | CNCE | Nonstatutory Stock Option (right to buy) | D | 13,29 | 10 000 | 10 000 | |||||
| 2017-03-13 | 2016-01-20 | 4/A | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −8 000 | 11 469 | |||||
| 2017-03-13 | 2017-03-09 | 4 | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −11 469 | 0 | |||||
| 2017-03-13 | 2017-03-09 | 4 | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −19 497 | 0 | |||||
| 2017-03-13 | 2017-03-09 | 4 | Silverman Robert | CNCE | Common Stock | D | 16,8600 | −768 | −13 | 50 307 | ||||
| 2017-03-13 | 2017-03-09 | 4 | Silverman Robert | CNCE | Common Stock | D | 1,1300 | 11 469 | 13 | 51 075 | ||||
| 2017-03-13 | 2017-03-09 | 4 | Silverman Robert | CNCE | Common Stock | D | 16,8600 | −1 306 | −22 | 39 606 | ||||
| 2017-03-13 | 2017-03-09 | 4 | Silverman Robert | CNCE | Common Stock | D | 1,1300 | 19 497 | 22 | 40 912 | ||||
| 2017-03-09 | 2017-03-08 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −2 098 | 0 | |||||
| 2017-03-09 | 2017-03-08 | 4 | Stuart Nancy | CNCE | Common Stock | D | 16,0400 | −147 | −2 | 40 902 | ||||
| 2017-03-09 | 2017-03-08 | 4 | Stuart Nancy | CNCE | Common Stock | D | 1,1300 | 2 098 | 2 | 41 049 | ||||
| 2017-01-06 | 2017-01-04 | 4 | Cassella James V | CNCE | Employee Stock Option (right to buy) | D | 10,97 | 70 000 | 70 000 | |||||
| 2017-01-06 | 2017-01-04 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 10,97 | 70 000 | 70 000 | |||||
| 2017-01-06 | 2017-01-04 | 4 | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 10,97 | 55 000 | 55 000 | |||||
| 2017-01-06 | 2017-01-04 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 10,97 | 200 000 | 200 000 | |||||
| 2017-01-06 | 2017-01-04 | 4 | Daws D. Ryan | CNCE | Employee Stock Option (right to buy) | D | 10,97 | 82 500 | 82 500 | |||||
| 2016-12-07 | 2015-06-23 | 5/A | Stuart Nancy | CNCE | Common Stock | D | −1 000 | 33 748 | ||||||
| 2016-12-07 | 2016-12-06 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −7 100 | 2 098 | |||||
| 2016-12-07 | 2016-12-06 | 4 | Stuart Nancy | CNCE | Common Stock | D | 8,9400 | −897 | −8 | 38 951 | ||||
| 2016-12-07 | 2016-12-06 | 4 | Stuart Nancy | CNCE | Common Stock | D | 1,1300 | 7 100 | 8 | 39 848 | ||||
| 2016-12-07 | 2016-11-29 | 4 | Stuart Nancy | CNCE | Common Stock | D | −1 000 | 32 748 | ||||||
| 2016-11-21 | 2016-11-14 | 4 | HUTT PETER BARTON | CNCE | Non-qualified Stock Option (right to buy) | D | 1,13 | −22 123 | 0 | |||||
| 2016-11-21 | 2016-11-14 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | 9,8100 | −22 123 | −217 | 0 | ||||
| 2016-11-21 | 2016-11-14 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | 1,1300 | 22 123 | 25 | 22 123 | ||||
| 2016-06-10 | 2016-06-09 | 4 | Barrett Ronald W | CNCE | Nonstatutory Stock Option (right to buy) | D | 12,96 | 10 000 | 10 000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | WIERENGA WENDALL | CNCE | Nonstatutory Stock Option (right to buy) | D | 12,96 | 10 000 | 10 000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | ALDRICH RICHARD | CNCE | Nonstatutory Stock Option (right to buy) | D | 12,96 | 10 000 | 10 000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | HUTT PETER BARTON | CNCE | Nonstatutory Stock Option (right to buy) | D | 12,96 | 10 000 | 10 000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | JAEGER WILFRED E | CNCE | Nonstatutory Stock Option (right to buy) | D | 12,96 | 10 000 | 10 000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | Auchincloss Thomas G | CNCE | Nonstatutory Stock Option (right to buy) | D | 12,96 | 10 000 | 10 000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | van Heek Christi | CNCE | Nonstatutory Stock Option (right to buy) | D | 12,96 | 25 000 | 25 000 | |||||
| 2016-05-16 | 2016-05-12 | 4 | Auchincloss Thomas G | CNCE | Common Stock | D | 10,1056 | 2 000 | 20 | 2 000 | ||||
| 2016-05-12 | 2016-05-11 | 4 | Tung Roger D | CNCE | Common Stock | D | 10,5500 | 19 610 | 207 | 538 965 | ||||
| 2016-03-23 | 2016-03-22 | 4 | Fitzgerald Meghan | CNCE | Nonstatutory Stock Option (right to buy) | D | 13,68 | 25 000 | 25 000 | |||||
| 2016-01-21 | 2016-01-20 | 4 | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −8 000 | 11 497 | |||||
| 2016-01-21 | 2016-01-20 | 4 | Silverman Robert | CNCE | Common Stock | D | 1,1300 | 8 000 | 9 | 21 415 | ||||
| 2016-01-13 | 2016-01-11 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 4,58 | −18 000 | 35 097 | |||||
| 2016-01-13 | 2016-01-11 | 4 | Tung Roger D | CNCE | Common Stock | D | 4,5800 | 18 000 | 82 | 519 355 | ||||
| 2016-01-13 | 2015-07-07 | 4 | Tung Roger D By Roger D. Tung 2011 GRAT | CNCE | Common Stock | I | −12 888 | 121 873 | ||||||
| 2016-01-13 | 2015-07-07 | 4 | Tung Roger D | CNCE | Common Stock | D | 12 888 | 501 355 | ||||||
| 2016-01-08 | 2015-06-23 | 5 | Stuart Nancy | CNCE | Common Stock | D | −1 000 | 32 748 | ||||||
| 2016-01-08 | 2016-01-07 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 16,85 | 170 000 | 170 000 | |||||
| 2016-01-08 | 2016-01-07 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 16,85 | 80 000 | 80 000 | |||||
| 2016-01-08 | 2016-01-07 | 4 | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 16,85 | 50 000 | 50 000 | |||||
| 2016-01-08 | 2016-01-07 | 4 | Daws D. Ryan | CNCE | Employee Stock Option (right to buy) | D | 16,85 | 50 000 | 50 000 | |||||
| 2016-01-08 | 2016-01-07 | 4 | McGowan Pauline | CNCE | Employee Stock Option (right to buy) | D | 16,85 | 15 000 | 15 000 | |||||
| 2016-01-08 | 2016-01-07 | 4 | Cassella James V | CNCE | Employee Stock Option (right to buy) | D | 16,85 | 50 000 | 50 000 | |||||
| 2015-12-17 | 2015-12-16 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 19,7595 | −20 000 | −395 | 286 975 | ||||
| 2015-12-16 | 2015-12-16 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 19,5656 | −113 | −2 | 0 | ||||
| 2015-12-16 | 2015-12-16 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 19,5656 | −5 066 | −99 | 0 | ||||
| 2015-12-16 | 2015-12-16 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 19,5656 | −265 | −5 | 0 | ||||
| 2015-12-16 | 2015-12-16 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 19,5656 | −4 916 | −96 | 0 | ||||
| 2015-12-16 | 2015-12-15 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 20,1041 | −589 | −12 | 113 | ||||
| 2015-12-16 | 2015-12-15 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 20,1041 | −26 697 | −537 | 5 066 | ||||
| 2015-12-16 | 2015-12-15 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 20,1041 | −1 392 | −28 | 265 | ||||
| 2015-12-16 | 2015-12-15 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 20,1041 | −25 894 | −521 | 4 916 | ||||
| 2015-12-16 | 2015-12-14 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 20,0881 | −42 | −1 | 702 | ||||
| 2015-12-16 | 2015-12-14 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 20,0881 | −1 919 | −39 | 31 763 | ||||
| 2015-12-16 | 2015-12-14 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 20,0881 | −100 | −2 | 1 657 | ||||
| 2015-12-16 | 2015-12-14 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 20,0881 | −1 861 | −37 | 30 810 | ||||
| 2015-12-15 | 2015-12-14 | 4 | McGowan Pauline | CNCE | Employee Stock Option (right to buy) | D | 3,50 | −498 | 0 | |||||
| 2015-12-15 | 2015-12-14 | 4 | McGowan Pauline | CNCE | Common Stock | D | 20,0735 | −498 | −10 | 0 | ||||
| 2015-12-15 | 2015-12-14 | 4 | McGowan Pauline | CNCE | Common Stock | D | 3,5000 | 498 | 2 | 498 | ||||
| 2015-11-23 | 2015-11-17 | 4 | Tung Roger D | CNCE | Common Stock | D | −350 | 488 467 | ||||||
| 2015-11-23 | 2015-11-17 | 4 | Tung Roger D | CNCE | Common Stock | D | −1 000 | 488 817 | ||||||
| 2015-11-23 | 2014-12-12 | 4 | Tung Roger D | CNCE | Common Stock | D | −200 | 489 817 | ||||||
| 2015-11-12 | 2015-11-11 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −9 200 | 9 198 | |||||
| 2015-11-12 | 2015-11-11 | 4 | Stuart Nancy | CNCE | Common Stock | D | 22,7800 | −456 | −10 | 33 748 | ||||
| 2015-11-12 | 2015-11-11 | 4 | Stuart Nancy | CNCE | Common Stock | D | 1,1300 | 9 200 | 10 | 34 204 | ||||
| 2015-11-10 | 2015-11-09 | 4 | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −3 600 | 19 497 | |||||
| 2015-11-10 | 2015-11-09 | 4 | Silverman Robert | CNCE | Common Stock | D | 21,9500 | −185 | −4 | 13 415 | ||||
| 2015-11-10 | 2015-11-09 | 4 | Silverman Robert | CNCE | Common Stock | D | 1,1300 | 3 600 | 4 | 13 600 | ||||
| 2015-11-10 | 2015-11-09 | 4 | Barrett Ronald W | CNCE | Non-qualified Stock Option (right to buy) | D | 1,13 | −17 699 | 0 | |||||
| 2015-11-10 | 2015-11-09 | 4 | Barrett Ronald W | CNCE | Common Stock | D | 21,9000 | −10 000 | −219 | 0 | ||||
| 2015-11-10 | 2015-11-09 | 4 | Barrett Ronald W | CNCE | Common Stock | D | 22,7500 | −7 699 | −175 | 10 000 | ||||
| 2015-11-10 | 2015-11-09 | 4 | Barrett Ronald W | CNCE | Common Stock | D | 1,1300 | 17 699 | 20 | 17 699 | ||||
| 2015-11-03 | 2015-11-02 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 0,57 | −23 216 | 0 | |||||
| 2015-11-03 | 2015-11-02 | 4 | Stuart Nancy | CNCE | Common Stock | D | 24,2944 | −23 216 | −564 | 25 004 | ||||
| 2015-11-03 | 2015-11-02 | 4 | Stuart Nancy | CNCE | Common Stock | D | 0,5700 | 23 216 | 13 | 48 220 | ||||
| 2015-09-22 | 2015-09-18 | 4 | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −5 000 | 23 097 | |||||
| 2015-09-22 | 2015-09-18 | 4 | Silverman Robert | CNCE | Common Stock | D | 20,0000 | −5 000 | −100 | 10 000 | ||||
| 2015-09-22 | 2015-09-18 | 4 | Silverman Robert | CNCE | Common Stock | D | 20,0000 | −5 000 | −100 | 10 000 | ||||
| 2015-09-22 | 2015-09-18 | 4 | Silverman Robert | CNCE | Common Stock | D | 1,1300 | 5 000 | 6 | 20 000 | ||||
| 2015-09-15 | 2015-09-14 | 4 | McGowan Pauline | CNCE | Employee Stock Option (right to buy) | D | 3,50 | −497 | 498 | |||||
| 2015-09-15 | 2015-09-14 | 4 | McGowan Pauline | CNCE | Common Stock | D | 18,9745 | −497 | −9 | 0 | ||||
| 2015-09-15 | 2015-09-14 | 4 | McGowan Pauline | CNCE | Common Stock | D | 3,5000 | 497 | 2 | 497 | ||||
| 2015-09-15 | 2015-09-14 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −17 000 | 18 398 | |||||
| 2015-09-15 | 2015-09-14 | 4 | Stuart Nancy | CNCE | Common Stock | D | 19,2700 | −996 | −19 | 25 004 | ||||
| 2015-09-15 | 2015-09-14 | 4 | Stuart Nancy | CNCE | Common Stock | D | 1,1300 | 17 000 | 19 | 26 000 | ||||
| 2015-09-14 | 2015-09-10 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 18,2200 | −1 296 | −24 | 744 | ||||
| 2015-09-14 | 2015-09-10 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 18,2200 | −58 704 | −1 070 | 33 682 | ||||
| 2015-09-14 | 2015-09-10 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 18,2200 | −3 062 | −56 | 1 757 | ||||
| 2015-09-14 | 2015-09-10 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 18,2200 | −56 938 | −1 037 | 32 671 | ||||
| 2015-08-28 | 2015-08-26 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | 82 405 | 82 405 | ||||||
| 2015-08-28 | 2015-08-26 | 4 | ALDRICH RICHARD | CNCE | Common Stock | I | −82 405 | 0 | ||||||
| 2015-08-18 | 2015-08-18 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 15,7000 | −6 805 | −107 | 2 040 | ||||
| 2015-08-18 | 2015-08-18 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 15,7000 | −308 195 | −4 839 | 92 386 | ||||
| 2015-08-18 | 2015-08-18 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 15,7000 | −16 071 | −252 | 4 819 | ||||
| 2015-08-18 | 2015-08-18 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 15,7000 | −298 929 | −4 693 | 89 609 | ||||
| 2015-08-18 | 2015-08-14 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 16,3200 | −1 404 | −23 | 8 845 | ||||
| 2015-08-18 | 2015-08-14 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 16,3200 | −63 596 | −1 038 | 400 581 | ||||
| 2015-08-18 | 2015-08-14 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 16,3200 | −3 316 | −54 | 20 890 | ||||
| 2015-08-18 | 2015-08-14 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 16,3200 | −61 684 | −1 007 | 388 538 | ||||
| 2015-08-17 | 2015-08-13 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 16,7500 | −996 | −17 | 10 249 | ||||
| 2015-08-17 | 2015-08-13 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 16,7500 | −45 112 | −756 | 464 177 | ||||
| 2015-08-17 | 2015-08-13 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 16,7500 | −2 352 | −39 | 24 206 | ||||
| 2015-08-17 | 2015-08-13 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 16,7500 | −43 755 | −733 | 450 222 | ||||
| 2015-08-14 | 2015-08-12 | 4/A | JAEGER WILFRED E | CNCE | Common Stock | I | 17,4897 | −1 056 | −18 | 11 245 | ||||
| 2015-08-14 | 2015-08-12 | 4/A | JAEGER WILFRED E | CNCE | Common Stock | I | 17,4897 | −47 837 | −837 | 509 289 | ||||
| 2015-08-14 | 2015-08-12 | 4/A | JAEGER WILFRED E | CNCE | Common Stock | I | 17,4897 | −2 494 | −44 | 26 558 | ||||
| 2015-08-14 | 2015-08-12 | 4/A | JAEGER WILFRED E | CNCE | Common Stock | I | 17,4897 | −46 398 | −811 | 493 977 | ||||
| 2015-08-14 | 2015-08-12 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 14,4897 | −1 056 | −15 | 11 245 | ||||
| 2015-08-14 | 2015-08-12 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 14,4897 | −47 837 | −693 | 509 289 | ||||
| 2015-08-14 | 2015-08-12 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 14,4897 | −2 494 | −36 | 26 558 | ||||
| 2015-08-14 | 2015-08-12 | 4 | JAEGER WILFRED E | CNCE | Common Stock | I | 14,4897 | −46 398 | −672 | 493 977 | ||||
| 2015-06-16 | 2015-06-12 | 4 | McGowan Pauline | CNCE | Employee Stock Option (right to buy) | D | 3,50 | −498 | 995 | |||||
| 2015-06-16 | 2015-06-12 | 4 | McGowan Pauline | CNCE | Common Stock | D | 16,0823 | −498 | −8 | 0 | ||||
| 2015-06-16 | 2015-06-12 | 4 | McGowan Pauline | CNCE | Common Stock | D | 3,5000 | 498 | 2 | 498 | ||||
| 2015-06-15 | 2015-06-11 | 4 | Barrett Ronald W | CNCE | Nonstatutory Stock Option (right to buy) | D | 16,42 | 10 000 | 10 000 | |||||
| 2015-06-15 | 2015-06-11 | 4 | WIERENGA WENDALL | CNCE | Nonstatutory Stock Option (right to buy) | D | 16,42 | 10 000 | 10 000 | |||||
| 2015-06-15 | 2015-06-11 | 4 | SCHUHSLER HELMUT | CNCE | Nonstatutory Stock Option (right to buy) | D | 16,42 | 10 000 | 10 000 | |||||
| 2015-06-15 | 2015-06-11 | 4 | JAEGER WILFRED E | CNCE | Nonstatutory Stock Option (right to buy) | D | 16,42 | 10 000 | 10 000 | |||||
| 2015-06-15 | 2015-06-11 | 4 | ALDRICH RICHARD | CNCE | Nonstatutory Stock Option (right to buy) | D | 16,42 | 10 000 | 10 000 | |||||
| 2015-06-15 | 2015-06-11 | 4 | HUTT PETER BARTON | CNCE | Nonstatutory Stock Option (right to buy) | D | 16,42 | 10 000 | 10 000 | |||||
| 2015-06-15 | 2015-06-11 | 4 | Auchincloss Thomas G | CNCE | Nonstatutory Stock Option (right to buy) | D | 16,42 | 10 000 | 10 000 | |||||
| 2015-06-10 | 2015-06-08 | 4 | Silverman Robert | CNCE | Common Stock | D | 16,3516 | −5 000 | −82 | 15 000 | ||||
| 2015-03-13 | 2015-03-13 | 4 | McGowan Pauline | CNCE | Employee Stock Option (right to buy) | D | 3,50 | −498 | 1 493 | |||||
| 2015-03-13 | 2015-03-13 | 4 | McGowan Pauline | CNCE | Common Stock | D | 16,0000 | −498 | −8 | 0 | ||||
| 2015-03-13 | 2015-03-13 | 4 | McGowan Pauline | CNCE | Common Stock | D | 3,5000 | 498 | 2 | 498 | ||||
| 2015-03-12 | 2015-03-11 | 4 | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −5 000 | 28 097 | |||||
| 2015-03-12 | 2015-03-11 | 4 | Silverman Robert | CNCE | Common Stock | D | 16,0000 | −5 000 | −80 | 20 000 | ||||
| 2015-03-12 | 2015-03-11 | 4 | Silverman Robert | CNCE | Common Stock | D | 1,1300 | 5 000 | 6 | 25 000 | ||||
| 2015-03-12 | 2015-03-11 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 0,57 | −46 430 | 23 216 | |||||
| 2015-03-12 | 2015-03-11 | 4 | Stuart Nancy | CNCE | Common Stock | D | 15,0000 | −46 430 | −696 | 10 000 | ||||
| 2015-03-12 | 2015-03-11 | 4 | Stuart Nancy | CNCE | Common Stock | D | 0,5700 | 46 430 | 26 | 56 430 | ||||
| 2015-03-12 | 2015-03-11 | 4 | McGowan Pauline | CNCE | Employee Stock Option (right to buy) | D | 3,50 | 3,5000 | −5 973 | −21 | 1 991 | |||
| 2015-03-12 | 2015-03-11 | 4 | McGowan Pauline | CNCE | Common Stock | D | 16,0000 | −5 973 | −96 | 0 | ||||
| 2015-03-12 | 2015-03-11 | 4 | McGowan Pauline | CNCE | Common Stock | D | 3,5000 | 5 973 | 21 | 5 973 | ||||
| 2015-03-11 | 2015-03-10 | 4 | McGowan Pauline | CNCE | Employee Stock Option (right to buy) | D | 3,79 | −7 079 | 0 | |||||
| 2015-03-11 | 2015-03-10 | 4 | McGowan Pauline | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −6 194 | 0 | |||||
| 2015-03-11 | 2015-03-10 | 4 | McGowan Pauline | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −8 849 | 0 | |||||
| 2015-03-11 | 2015-03-10 | 4 | McGowan Pauline | CNCE | Common Stock | D | 13,9000 | −7 079 | −98 | 0 | ||||
| 2015-03-11 | 2015-03-10 | 4 | McGowan Pauline | CNCE | Common Stock | D | 3,7900 | 7 079 | 27 | 7 079 | ||||
| 2015-03-11 | 2015-03-10 | 4 | McGowan Pauline | CNCE | Common Stock | D | 13,9000 | −6 194 | −86 | 0 | ||||
| 2015-03-11 | 2015-03-10 | 4 | McGowan Pauline | CNCE | Common Stock | D | 1,1300 | 6 194 | 7 | 6 194 | ||||
| 2015-03-11 | 2015-03-10 | 4 | McGowan Pauline | CNCE | Common Stock | D | 13,9000 | −8 849 | −123 | 0 | ||||
| 2015-03-11 | 2015-03-10 | 4 | McGowan Pauline | CNCE | Common Stock | D | 1,1300 | 8 849 | 10 | 8 849 | ||||
| 2015-03-06 | 2015-03-05 | 4 | Cassella James V | CNCE | Employee Stock Option (right to buy) | D | 14,46 | 140 000 | 140 000 | |||||
| 2015-02-19 | 2015-02-17 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −28 495 | 0 | |||||
| 2015-02-19 | 2015-02-17 | 4 | Tung Roger D | CNCE | Common Stock | D | 1,1300 | 28 495 | 32 | 490 017 | ||||
| 2014-12-12 | 2014-12-11 | 4 | Auchincloss Thomas G | CNCE | Nonstatutory Stock Option (right to buy) | D | 11,19 | 25 000 | 25 000 | |||||
| 2014-11-20 | 2014-11-18 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Common Stock | I | 12,2900 | −12 755 | −157 | 29 052 | ||||
| 2014-11-20 | 2014-11-18 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Common Stock | I | 12,2900 | −237 245 | −2 916 | 540 375 | ||||
| 2014-11-20 | 2014-11-18 | 4 | Three Arch Management IV, L.L.C. | CNCE | Common Stock | I | 12,2900 | −5 400 | −66 | 12 301 | ||||
| 2014-11-20 | 2014-11-18 | 4 | Three Arch Management IV, L.L.C. | CNCE | Common Stock | I | 12,2900 | −244 600 | −3 006 | 557 126 | ||||
| 2014-10-21 | 2014-10-16 | 4 | ALDRICH RICHARD By Richard H. Aldrich Irrevocable Trust of 2011 | CNCE | Common Stock | I | 82 405 | 82 405 | ||||||
| 2014-10-21 | 2014-10-16 | 4 | ALDRICH RICHARD By Richard H. Aldrich 2011 GRAT | CNCE | Common Stock | I | −82 405 | 0 | ||||||
| 2014-10-21 | 2014-10-16 | 4 | ALDRICH RICHARD | CNCE | Common Stock | D | 20 012 | 306 975 | ||||||
| 2014-10-21 | 2014-10-16 | 4 | ALDRICH RICHARD By Richard H. Aldrich 2011 GRAT | CNCE | Common Stock | I | −20 012 | 82 405 | ||||||
| 2014-06-12 | 2014-06-10 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 8,40 | 100 000 | 100 000 | |||||
| 2014-06-12 | 2014-06-10 | 4 | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 8,40 | 73 000 | 73 000 | |||||
| 2014-06-12 | 2014-06-10 | 4 | McGowan Pauline | CNCE | Employee Stock Option (right to buy) | D | 8,40 | 29 000 | 29 000 | |||||
| 2014-06-12 | 2014-06-10 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 8,40 | 203 300 | 203 300 | |||||
| 2014-06-12 | 2014-06-10 | 4 | Daws D. Ryan | CNCE | Employee Stock Option (right to buy) | D | 8,40 | 50 000 | 50 000 | |||||
| 2014-06-02 | 2014-05-29 | 4 | Stuart Nancy | CNCE | Employee Stock Option (right to buy) | D | 0,57 | −10 000 | 69 646 | |||||
| 2014-06-02 | 2014-05-29 | 4 | Stuart Nancy | CNCE | Common Stock | D | 0,5700 | 10 000 | 6 | 10 000 | ||||
| 2014-06-02 | 2014-05-29 | 4 | Silverman Robert | CNCE | Employee Stock Option (right to buy) | D | 1,13 | 20 000 | 33 097 | |||||
| 2014-06-02 | 2014-05-29 | 4 | Silverman Robert | CNCE | Common Stock | D | 1,1300 | 20 000 | 23 | 20 000 | ||||
| 2014-05-23 | 2014-05-22 | 4 | Tung Roger D | CNCE | Employee Stock Option (right to buy) | D | 1,13 | −60 000 | 28 495 | |||||
| 2014-05-23 | 2014-05-22 | 4 | Tung Roger D | CNCE | Common Stock | D | 1,1300 | 60 000 | 68 | 461 522 | ||||
| 2014-03-17 | 3 | WIERENGA WENDALL | CNCE | Common Stock | D | 24 778 | ||||||||
| 2014-03-17 | 3 | WIERENGA WENDALL | CNCE | Common Stock | D | 24 778 | ||||||||
| 2014-03-17 | 2014-03-13 | 4 | WIERENGA WENDALL | CNCE | Employee Stock Option (right to buy) | D | 13,91 | 25 000 | 25 000 | |||||
| 2014-02-21 | 2014-02-20 | 4 | Freund John Gordon | CNCE | Series C Convertible Preferred Stock | I | −600 000 | 0 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Freund John Gordon | CNCE | Series B Convertible Preferred Stock | I | −3 000 000 | 0 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Freund John Gordon | CNCE | Series A Convertible Preferred Stock | I | −2 200 000 | 0 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Freund John Gordon | CNCE | Common Stock | I | 14,0000 | 150 000 | 2 100 | 1 208 920 | ||||
| 2014-02-21 | 2014-02-20 | 4 | Freund John Gordon | CNCE | Common Stock | I | 106 194 | 1 058 920 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Freund John Gordon | CNCE | Common Stock | I | 530 974 | 952 726 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Freund John Gordon | CNCE | Common Stock | I | 389 380 | 421 752 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Bain Capital Public Equity Management, LLC | CNCE | SERIES C CONVERTIBLE PREFERRED STOCK | I | −2 000 000 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Bain Capital Public Equity Management, LLC | CNCE | SERIES B CONVERTIBLE PREFERRED STOCK | I | −4 300 000 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Bain Capital Public Equity Management, LLC | CNCE | COMMON STOCK | I | 14,0000 | 350 000 | 4 900 | 1 497 833 | ||||
| 2014-02-21 | 2014-02-19 | 4 | Bain Capital Public Equity Management, LLC | CNCE | COMMON STOCK | I | 353 982 | 1 147 833 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Bain Capital Public Equity Management, LLC | CNCE | COMMON STOCK | I | 761 062 | 793 851 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Series C Convertible Preferred Stock | I | −379 592 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Series B Convertible Preferred Stock | I | −1 897 959 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Series A Convertible Preferred Stock | I | −1 423 469 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Series C Convertible Preferred Stock | I | −20 408 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Series B Convertible Preferred Stock | I | −102 041 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Series A Convertible Preferred Stock | I | −76 531 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Common Stock | I | 14,0000 | 98 219 | 1 375 | 777 620 | ||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Common Stock | I | 14,0000 | 5 281 | 74 | 41 807 | ||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Common Stock | I | 67 184 | 679 401 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Common Stock | I | 335 922 | 612 217 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Common Stock | I | 251 941 | 276 295 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Common Stock | I | 3 612 | 36 526 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Common Stock | I | 18 060 | 32 914 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | THREE ARCH MANAGEMENT III LLC | CNCE | Common Stock | I | 13 545 | 14 854 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Series C Convertible Preferred Stock | I | −391 359 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Series B Convertible Preferred Stock | I | −1 956 794 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Series A Convertible Preferred Stock | I | −1 467 595 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Series C Convertible Preferred Stock | I | −8 641 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Series B Convertible Preferred Stock | I | −43 206 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Series A Convertible Preferred Stock | I | −32 405 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Common Stock | I | 14,0000 | 101 264 | 1 418 | 801 726 | ||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Common Stock | I | 14,0000 | 2 236 | 31 | 17 701 | ||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Common Stock | I | 69 267 | 700 462 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Common Stock | I | 346 335 | 631 195 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Common Stock | I | 259 751 | 284 860 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Common Stock | I | 1 529 | 15 465 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Common Stock | I | 7 647 | 13 936 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | Three Arch Management IV, L.L.C. | CNCE | Common Stock | I | 5 735 | 6 289 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | CNCE | Series C Convertible Preferred Stock | I | −600 000 | 0 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | CNCE | Series B Convertible Preferred Stock | I | −3 000 000 | 0 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | CNCE | Series A Convertible Preferred Stock | I | −2 200 000 | 0 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | CNCE | Common Stock | I | 14,0000 | 150 000 | 2 100 | 1 208 920 | ||||
| 2014-02-21 | 2014-02-20 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | CNCE | Common Stock | I | 106 194 | 1 058 920 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | CNCE | Common Stock | I | 530 974 | 952 726 | ||||||
| 2014-02-21 | 2014-02-20 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | CNCE | Common Stock | I | 389 380 | 421 752 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | QVT Associates GP LLC Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P. | CNCE | Series C Convertible Preferred Stock | I | −219 000 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | QVT Associates GP LLC Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P. | CNCE | Series B Convertible Preferred Stock | I | −1 000 000 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | QVT Associates GP LLC Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P. | CNCE | Series A Convertible Preferred Stock | I | −250 000 | 0 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | QVT Associates GP LLC Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P. | CNCE | Common Stock, $0.001 par value | I | 14,0000 | 300 000 | 4 200 | 559 999 | ||||
| 2014-02-21 | 2014-02-19 | 4 | QVT Associates GP LLC Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P. | CNCE | Common Stock, $0.001 par value | I | 259 999 | 259 999 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | New Leaf Ventures I, L.P. | CNCE | Series C Preferred Stock | D | 0,00 | 77 522 | 0 | |||||
| 2014-02-21 | 2014-02-19 | 4 | New Leaf Ventures I, L.P. | CNCE | Series B Preferred Stock | D | 0,00 | 442 478 | 0 | |||||
| 2014-02-21 | 2014-02-19 | 4 | New Leaf Ventures I, L.P. | CNCE | Common Stock | D | 13 721 | 107 327 | ||||||
| 2014-02-21 | 2014-02-19 | 4 | New Leaf Ventures I, L.P. | CNCE | Common Stock | D | 78 315 | 93 606 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | GLAXOSMITHKLINE PLC By Glaxo Group Limited | CNCE | Series D Convertible Preferred Stock | I | −6 666 667 | 0 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | GLAXOSMITHKLINE PLC By S.R. One Limited | CNCE | Series C Convertible Preferred Stock | I | −800 000 | 0 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | GLAXOSMITHKLINE PLC By S.R. One Limited | CNCE | Common Stock | I | 14,0000 | 35 000 | 490 | 1 356 533 | ||||
| 2014-02-20 | 2014-02-19 | 4 | GLAXOSMITHKLINE PLC By Glaxo Group Limited | CNCE | Common Stock | I | 1 179 941 | 1 321 533 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | GLAXOSMITHKLINE PLC By S.R. One Limited | CNCE | Common Stock | I | 141 592 | 141 592 | ||||||
| 2014-02-20 | 2014-02-20 | 4 | Adage Capital Partners, L.P. | CNCE | Common Stock, par value $0.001 per share | I | 495 575 | 510 147 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | Adage Capital Partners, L.P. | CNCE | Series C Convertible Preferred Stock | I | −2 800 000 | 0 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Sciences Ventures VI LP | CNCE | Series C Convertible Preferred Stock | I | −288 407 | 0 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Sciences Ventures VI LP | CNCE | Series B Convertible Preferred Stock | I | −1 084 813 | 0 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Sciences Ventures VI LP | CNCE | Series A Convertible Preferred Stock | I | −561 550 | 0 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG | CNCE | Series C Convertible Preferred Stock | D | −841 493 | 0 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG | CNCE | Series B Convertible Preferred Stock | D | −3 165 187 | 0 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG | CNCE | Series A Convertible Preferred Stock | D | −1 638 450 | 0 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 14,0000 | 22 713 | 318 | 378 703 | ||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG | CNCE | Common Stock | D | 14,0000 | 66 287 | 928 | 1 104 969 | ||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 51 045 | 355 990 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 192 003 | 304 945 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 99 389 | 112 942 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG | CNCE | Common Stock | D | 148 936 | 1 038 682 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG | CNCE | Common Stock | D | 560 211 | 889 746 | ||||||
| 2014-02-20 | 2014-02-19 | 4 | TVM Life Science Ventures VI GmbH & Co KG | CNCE | Common Stock | D | 289 991 | 329 535 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | ALDRICH RICHARD By RA Capital Associates, Inc. | CNCE | Series B Convertible Preferred Stock | I | −50 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | ALDRICH RICHARD By RA Capital Associates, Inc. | CNCE | Series A Convertible Preferred Stock | I | −300 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | ALDRICH RICHARD By RA Capital Associates, Inc. | CNCE | Common Stock | I | 8 849 | 61 946 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | ALDRICH RICHARD By RA Capital Associates, Inc. | CNCE | Common Stock | I | 53 097 | 53 097 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | HUTT PETER BARTON | CNCE | Series B Convertible Preferred Stock | D | −25 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | HUTT PETER BARTON | CNCE | Common Stock | D | 4 424 | 4 424 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Flagship Ventures Fund 2004 L P | CNCE | Series C Convertible Preferred Stock | D | −525 500 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Flagship Ventures Fund 2004 L P | CNCE | Series B Convertible Preferred Stock | D | −3 000 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Flagship Ventures Fund 2004 L P | CNCE | Common Stock | D | 93 008 | 656 490 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Flagship Ventures Fund 2004 L P | CNCE | Common Stock | D | 530 974 | 563 482 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII-A Limited Partnership | CNCE | Series C Convertible Preferred Stock | I | −38 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII-A Limited Partnership | CNCE | Series B Convertible Preferred Stock | I | −190 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII-A Limited Partnership | CNCE | Series A Convertible Preferred Stock | I | −152 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII Limited Partnership | CNCE | Series C Convertible Preferred Stock | I | −342 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII Limited Partnership | CNCE | Series B Convertible Preferred Stock | I | −1 710 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII Limited Partnership | CNCE | Series A Convertible Preferred Stock | I | −1 368 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII-A Limited Partnership | CNCE | Common Stock | I | 6 725 | 67 256 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII-A Limited Partnership | CNCE | Common Stock | I | 33 629 | 60 531 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII-A Limited Partnership | CNCE | Common Stock | I | 26 902 | 26 902 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII Limited Partnership | CNCE | Common Stock | I | 60 530 | 605 309 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII Limited Partnership | CNCE | Common Stock | I | 302 655 | 544 779 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Greylock XII GP LLC By Greylock XII Limited Partnership | CNCE | Common Stock | I | 242 124 | 242 124 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Tung Roger D By Tung Family Investment Trust | CNCE | Series B Convertible Preferred Stock | I | −25 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Tung Roger D By Tung Family Investment Trust | CNCE | Series A Convertible Preferred Stock | I | −50 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Tung Roger D | CNCE | Series A Convertible Preferred Stock | D | −100 000 | 0 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Tung Roger D By Tung Family Investment Trust | CNCE | Common Stock | I | 4 424 | 13 274 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Tung Roger D By Tung Family Investment Trust | CNCE | Common Stock | I | 8 850 | 8 850 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Tung Roger D | CNCE | Common Stock | D | 17 699 | 401 522 | ||||||
| 2014-02-19 | 2014-02-19 | 4 | Daws D. Ryan | CNCE | Employee Stock Option (right to buy) | D | 14,09 | 123 893 | 123 893 | |||||
| 2014-02-12 | 3 | Freund John Gordon | CNCE | Common Stock | I | 64 744 | ||||||||
| 2014-02-12 | 3 | Freund John Gordon | CNCE | Common Stock | I | 64 744 | ||||||||
| 2014-02-12 | 3 | BROOKSIDE CAPITAL PARTNERS FUND LP | CNCE | Common Stock | I | 65 578 | ||||||||
| 2014-02-12 | 3 | BROOKSIDE CAPITAL PARTNERS FUND LP | CNCE | Common Stock | I | 65 578 | ||||||||
| 2014-02-12 | 3 | BROOKSIDE CAPITAL PARTNERS FUND LP | CNCE | Common Stock | I | 65 578 | ||||||||
| 2014-02-12 | 3 | BROOKSIDE CAPITAL PARTNERS FUND LP | CNCE | Common Stock | I | 65 578 | ||||||||
| 2014-02-12 | 3 | ALDRICH RICHARD By Richard H. Aldrich 2011 GRAT | CNCE | Common Stock | I | 491 797 | ||||||||
| 2014-02-12 | 3 | ALDRICH RICHARD By Richard H. Aldrich 2011 GRAT | CNCE | Common Stock | I | 491 797 | ||||||||
| 2014-02-12 | 3 | ALDRICH RICHARD | CNCE | Common Stock | D | 676 343 | ||||||||
| 2014-02-12 | 3 | ALDRICH RICHARD | CNCE | Common Stock | D | 676 343 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 50 017 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 50 017 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 50 017 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 50 017 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 26 972 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 26 972 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 50 017 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 26 972 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 26 972 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 50 017 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 26 972 | ||||||||
| 2014-02-12 | 3 | JAEGER WILFRED E | CNCE | Common Stock | I | 26 972 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 26 217 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 26 217 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 50 772 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 50 772 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 26 217 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 26 217 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 50 772 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 26 217 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 50 772 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 50 772 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 26 217 | ||||||||
| 2014-02-12 | 3 | WAN MARK A | CNCE | Common Stock | I | 50 772 | ||||||||
| 2014-02-12 | 3 | KANEKO YASUNORI | CNCE | Common Stock | I | 64 744 | ||||||||
| 2014-02-12 | 3 | KANEKO YASUNORI | CNCE | Common Stock | I | 64 744 | ||||||||
| 2014-02-12 | 3 | KANEKO YASUNORI | CNCE | Common Stock | I | 64 744 | ||||||||
| 2014-02-12 | 3 | KANEKO YASUNORI | CNCE | Common Stock | I | 64 744 | ||||||||
| 2014-02-12 | 3 | KANEKO YASUNORI | CNCE | Common Stock | I | 64 744 | ||||||||
| 2014-02-12 | 3 | KANIA EDWIN M JR | CNCE | Common Stock | D | 65 016 | ||||||||
| 2014-02-12 | 3 | KANIA EDWIN M JR | CNCE | Common Stock | D | 65 016 | ||||||||
| 2014-02-12 | 3 | KANIA EDWIN M JR | CNCE | Common Stock | D | 65 016 | ||||||||
| 2014-02-12 | 3 | KANIA EDWIN M JR | CNCE | Common Stock | D | 65 016 | ||||||||
| 2014-02-12 | 3 | KANIA EDWIN M JR | CNCE | Common Stock | D | 65 016 | ||||||||
| 2014-02-12 | 3 | Gross Phillip See FN | N/A | Common stock, par value $0.001 per share | I | 29 144 | ||||||||
| 2014-02-12 | 3 | Gross Phillip See FN | N/A | Common stock, par value $0.001 per share | I | 29 144 | ||||||||
| 2014-02-12 | 3 | Gross Phillip See FN | N/A | Common stock, par value $0.001 per share | I | 29 144 | ||||||||
| 2014-02-12 | 3 | Gross Phillip See FN | N/A | Common stock, par value $0.001 per share | I | 29 144 | ||||||||
| 2014-02-12 | 3 | Gross Phillip See FN | N/A | Common stock, par value $0.001 per share | I | 29 144 | ||||||||
| 2014-02-12 | 3 | Gross Phillip See FN | N/A | Common stock, par value $0.001 per share | I | 29 144 | ||||||||
| 2014-02-12 | 3 | Ratcliffe Liam | CNCE | Common Stock | D | 30 582 | ||||||||
| 2014-02-12 | 3 | Ratcliffe Liam | CNCE | Common Stock | D | 30 582 | ||||||||
| 2014-02-12 | 3 | Ratcliffe Liam | CNCE | Common Stock | D | 30 582 | ||||||||
| 2014-02-12 | 3 | Ratcliffe Liam | CNCE | Common Stock | D | 30 582 | ||||||||
| 2014-02-12 | 3 | Ratcliffe Liam | CNCE | Common Stock | D | 30 582 | ||||||||
| 2014-02-12 | 3 | Ratcliffe Liam | CNCE | Common Stock | D | 30 582 | ||||||||
| 2014-02-12 | 3 | Ratcliffe Liam | CNCE | Common Stock | D | 30 582 | ||||||||
| 2014-02-12 | 3 | Ratcliffe Liam | CNCE | Common Stock | D | 30 582 | ||||||||
| 2014-02-12 | 3 | Ratcliffe Liam | CNCE | Common Stock | D | 30 582 | ||||||||
| 2014-02-12 | 3 | Ratcliffe Liam | CNCE | Common Stock | D | 30 582 | ||||||||
| 2014-02-12 | 3 | Tung Roger D By RD Tung Irrevocable Trust | CNCE | Common Stock | I | 543 362 | ||||||||
| 2014-02-12 | 3 | Tung Roger D By RD Tung Irrevocable Trust | CNCE | Common Stock | I | 543 362 | ||||||||
| 2014-02-12 | 3 | Tung Roger D By Roger D. Tung 2011 GRAT | CNCE | Common Stock | I | 665 734 | ||||||||
| 2014-02-12 | 3 | Tung Roger D | CNCE | Common Stock | D | 914 796 | ||||||||
| 2014-02-12 | 3 | Tung Roger D By Roger D. Tung 2011 GRAT | CNCE | Common Stock | I | 665 734 | ||||||||
| 2014-02-12 | 3 | Tung Roger D | CNCE | Common Stock | D | 914 796 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 66 650 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP | CNCE | Common Stock | D | 92 641 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 66 650 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP | CNCE | Common Stock | D | 92 641 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 66 650 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP | CNCE | Common Stock | D | 92 641 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 66 650 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP | CNCE | Common Stock | D | 92 641 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP | CNCE | Common Stock | D | 92 641 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 66 650 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP | CNCE | Common Stock | D | 92 641 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 66 650 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP | CNCE | Common Stock | D | 92 641 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 66 650 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP | CNCE | Common Stock | D | 92 641 | ||||||||
| 2014-02-12 | 3 | TVM Life Science Ventures VI LP By TVM Life Sciences Ventures VI LP | CNCE | Common Stock | I | 66 650 |
P
Köp på öppna marknaden eller privat köp av icke-derivatsäkerhet
S
Köp på öppna marknaden eller privat försäljning av icke-derivatsäkerhet
A
Bevilja, tilldelning eller annat förvärv av värdepapper från företaget (såsom en option)
C
Omvandling av derivat
D
Försäljning eller överföring av värdepapper tillbaka til företaget
F
Betalning av lösenpris eller skatteskuld med del av värdepapper som erhållits från bolaget
G
Överlåtelse av värdepapper från eller till insidern
K
Aktieswappar och liknande säkringsaffärer
M
Utövande eller omvandling av derivatsäkerhet som erhållits från företaget (som en option)
V
En transaktion friviligt rapporterad på schema 4
J
Andra (med en fotnot som beskriver transaktionen)
