MTP / Midatech Pharma Plc - ADR - SEC-arkiveringar, Årsredovisning, Fullmaktsutlåtande

Midatech Pharma Plc - ADR
US ˙ NASDAQ ˙ US59564R3021
DENNA SYMBOL ÄR INTE LÄNGRE AKTIV

Grundläggande statistik
LEI 549300GKR2G40H3QFY57
CIK 1643918
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Midatech Pharma Plc - ADR
SEC Filings (Chronological Order)
Denna sida innehåller en komplett, kronologisk lista över SEC-arkiveringar, exklusive ägande-arkiveringar som vi tillhandahåller på andra ställen.
August 18, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,100,000 Ordinary Shares Representing 24,861 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 8 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 2,486,100,000 Ordinary Shares Representing 24,861 American Depositary Shares This prospectus supplement No. 8 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended, e

August 18, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of August 2025 Commission File Number: 001-376

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of August 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Addres

August 18, 2025 EX-99.1

Biodexa Announces Enrolment of First Patients into Pivotal Phase 3 Serenta Trial in Familial Adenomatous Polyposis (FAP)

EXHIBIT 99.1 Biodexa Announces Enrolment of First Patients into Pivotal Phase 3 Serenta Trial in Familial Adenomatous Polyposis (FAP) August 18, 2025 Biodexa Announces Enrolment of First Patients into Pivotal Phase 3 Serenta Trial in Familial Adenomatous Polyposis (FAP) Opportunity to be First Mover in $7.3Bn Addressable Market Biodexa Pharmaceuticals PLC (“Biodexa” or “the Company”), (Nasdaq: BDR

August 18, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 3,413,520 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-284350 PROSPECTUS SUPPLEMENT No. 8 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 3,413,520 American Depositary Shares This prospectus supplement No. 8 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amend

August 18, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,000,000 Ordinary Shares Representing 43,490 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 8 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 4,349,000,000 Ordinary Shares Representing 43,490 American Depositary Shares This prospectus supplement No. 8 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended, e

August 6, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 3,413,520 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-284350 PROSPECTUS SUPPLEMENT No. 7 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 3,413,520 American Depositary Shares This prospectus supplement No. 7 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amend

August 6, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,100,000 Ordinary Shares Representing 24,861 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 7 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 2,486,100,000 Ordinary Shares Representing 24,861 American Depositary Shares This prospectus supplement No. 7 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended, e

August 6, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,000,000 Ordinary Shares Representing 43,490 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 7 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 4,349,000,000 Ordinary Shares Representing 43,490 American Depositary Shares This prospectus supplement No. 7 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended, e

July 31, 2025 EX-99.1

ADR Ratio Change Effective

EXHIBIT 99.1 ADR Ratio Change Effective July 31, 2025 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) ADR Ratio Change Effective ADSs Outstanding Post Ratio Change Biodexa Pharmaceuticals PLC (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, today announces the previously announce

July 31, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2025 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address

July 18, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-284350 PROSPECTUS SUPPLEMENT No. 6 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares This prospectus supplement No. 6 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amen

July 18, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 6 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares This prospectus supplement No. 6 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

July 18, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 6 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares This prospectus supplement No. 6 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

July 15, 2025 EX-99.1

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) ADR Ratio Change

Exhibit 99.1 July 15, 2025 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) ADR Ratio Change Biodexa Pharmaceuticals PLC (Nasdaq: BDRX), an acquisition-focused clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, today announces a ratio change on its American Depositary Receipts (“ADR”) from one (1) AD

July 15, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2025 Commission File Number 001-37652 Bio

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2025 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of pr

June 27, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-284350 PROSPECTUS SUPPLEMENT No. 5 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares This prospectus supplement No. 4 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amen

June 27, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 5 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares This prospectus supplement No. 3 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

June 27, 2025 EX-99.1

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Results of Annual General Meeting

Exhibit 99.1 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Results of Annual General Meeting Biodexa Pharmaceuticals PLC (NASDAQ: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, announces that at its Annual General Meeting held yesterday, all resolutions put to the Company’s shareholde

June 27, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2025 Commission File Number 001-37652 Bio

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2025 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of pr

June 27, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 5 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares This prospectus supplement No. 4 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

June 13, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2025 Commission File Number 001-37652 Bio

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2025 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of pr

June 13, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 4 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares This prospectus supplement No. 4 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

June 13, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-284350 PROSPECTUS SUPPLEMENT No. 4 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares This prospectus supplement No. 4 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amen

June 13, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 4 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares This prospectus supplement No. 4 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

June 13, 2025 EX-1.1

BIODEXA PHARMACEUTICALS PLC (registered number 09216368) ARTICLES OF ASSOCIATION Table of Contents

Exhibit 1.1 BIODEXA PHARMACEUTICALS PLC (registered number 09216368) ARTICLES OF ASSOCIATION Table of Contents PRELIMINARY 1 1 DEFINITIONS 1 2 LIABILITY OF MEMBERS 6 3 FORM OF RESOLUTION 6 4 EXCLUSION OF MODEL ARTICLES (AND ANY OTHER PRESCRIBED REGULATIONS) 6 5 REGISTERED OFFICE 6 SHARE CAPITAL 6 6 ALLOTMENT, REDUCTION AND ALTERATION 6 7 SHARE WARRANTS TO BEARER 7 8 COMMISSIONS AND BROKERAGE 8 9 T

June 11, 2025 EX-99.1

Result of General Meeting

EXHIBIT 99.1 Result of General Meeting June 11, 2025 Biodexa Pharmaceuticals PLC Result of General Meeting Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (NASDAQ: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs announces, announces that at its General Meeting held earlier today, all four

June 11, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2025 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address

June 4, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2025 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address

June 4, 2025 EX-99.1

Biodexa Announces Recruitment of First Patient in Phase 2 Study of Tolimidone in Type 1 Diabetes

EXHIBIT 99.1 Biodexa Announces Recruitment of First Patient in Phase 2 Study of Tolimidone in Type 1 Diabetes June 4, 2025 Biodexa Announces Recruitment of First Patient in Phase 2 Study of Tolimidone in Type 1 Diabetes Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment o

June 2, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 3 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares This prospectus supplement No. 3 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

June 2, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 3 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares This prospectus supplement No. 3 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

May 30, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address o

May 30, 2025 EX-99.1

Shareholder Update

EXHIBIT 99.1 Shareholder Update May 30, 2025 Biodexa Pharmaceuticals PLC Shareholder Update Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, today announced a brief update for shareholders. Financial position As of May 29, 2025, the

May 30, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-284350 PROSPECTUS SUPPLEMENT No. 3 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares This prospectus supplement No. 3 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amen

May 23, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number 001-37652 Biod

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of pri

May 23, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 2 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares This prospectus supplement No. 2 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

May 23, 2025 EX-99.2

NOTICE OF ANNUAL GENERAL MEETING BIODEXA PHARMACEUTICALS PLC (Incorporated and registered in England and Wales with registered no. 09216368)

Exhibit 99.2 NOTICE OF ANNUAL GENERAL MEETING BIODEXA PHARMACEUTICALS PLC (Incorporated and registered in England and Wales with registered no. 09216368) Notice is hereby given that an Annual General Meeting (“AGM”) of the members of Biodexa Pharmaceuticals PLC (the “Company”) will be held at 1 Caspian Point, Caspian Way, Cardiff, Wales, CF10 4DQ on 26 June 2025 at 1:00 p.m. to consider and, if th

May 23, 2025 EX-99.3

If you are planning to attend the Annual General Meeting, please tick the following box:Ñ>123|Ó>123-0Ordinary ResolutionsFORM OF PROXYBiodexa Pharmaceuticals PLC(a company incorporated in England and Wales under the Companies Act 2006 with company nu

Exhibit 99.3 If you are planning to attend the Annual General Meeting, please tick the following box:Ñ>123|Ó>123-0Ordinary ResolutionsFORM OF PROXYBiodexa Pharmaceuticals PLC(a company incorporated in England and Wales under the Companies Act 2006 with company number 09216368)I?We being (a) member(s) of the Company and entitled to vote at the AnnualGeneral Meeting, hereby appoint(Please only compl

May 23, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-284350 PROSPECTUS SUPPLEMENT No. 2 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares This prospectus supplement No. 2 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amen

May 23, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 2 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares This prospectus supplement No. 2 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

May 23, 2025 EX-99.4

Proof 6 20-May-25 FOR AGAINST WITHHELD FOR AGAINST WITHHELD Res 1. Res 5. Res 2. Res 6. Res 3. Res 7. Res 4. BIODEXA PHARMACEUTICALS PLC TO THE REGISTERED HOLDERS OF AMERICAN DEPOSITARY RECEIPTS ("ADRs") REPRESENTING ORDINARY SHARES OF BIODEXA PHARMA

Exhibit 99.4 Proof 6 20-May-25 FOR AGAINST WITHHELD FOR AGAINST WITHHELD Res 1. Res 5. Res 2. Res 6. Res 3. Res 7. Res 4. BIODEXA PHARMACEUTICALS PLC TO THE REGISTERED HOLDERS OF AMERICAN DEPOSITARY RECEIPTS ("ADRs") REPRESENTING ORDINARY SHARES OF BIODEXA PHARMACEUTICALS PLC Sign below Date: Please sign this Voting Instruction Card exactly as your name(s) appear(s) on the face of this card and on

May 22, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number 001-37652 Biod

6-K 1 z5212516k.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kin

May 22, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address o

May 22, 2025 EX-99.2

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Notice of General Meeting

Exhibit 99.2 May 22, 2025 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Notice of General Meeting Biodexa Pharmaceuticals PLC, (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs announces a Notice of a General Meeting to be held at the Company’s offices, 1 Caspian Point, Caspian W

May 22, 2025 EX-99.1

NOTICE OF GENERAL MEETING BIODEXA PHARMACEUTICALS PLC (Incorporated and registered in England and Wales with registered no. 09216368)

Exhibit 99.1 NOTICE OF GENERAL MEETING BIODEXA PHARMACEUTICALS PLC (Incorporated and registered in England and Wales with registered no. 09216368) Notice is hereby given that a general meeting (“GM”) of the members of Biodexa Pharmaceuticals PLC (the “Company”) will be held at 1 Caspian Point, Caspian Way, Cardiff, Wales, CF10 4DQ on 11 June 2025 at 1:00 p.m. to consider and, if thought fit, pass

May 22, 2025 EX-99.1

Biodexa Announces Award of Additional $3.0M Grant from CPRIT to Support Registrational eRapa Phase 3 Program in FAP Brings Total CPRIT Grant Funding for eRapa Phase 3 Program to $20.0M

EXHIBIT 99.1 Biodexa Announces Award of Additional $3.0M Grant from CPRIT to Support Registrational eRapa Phase 3 Program in FAP Brings Total CPRIT Grant Funding for eRapa Phase 3 Program to $20.0M May 22, 2025 Biodexa Announces Award of Additional $3.0M Grant from CPRIT to Support Registrational eRapa Phase 3 Program in FAP Brings Total CPRIT Grant Funding for eRapa Phase 3 Program to $20.0M Biod

May 15, 2025 EX-10.1

Annex A – Representations and Warranties

Exhibit 10.1 May 15, 2025 [Name and address of warrant holder] Re: Reprice of Warrants To Whom It May Concern: Biodexa Pharmaceuticals PLC, a public limited company organized under the laws of England and Wales (the “Company”), is pleased to offer to you the opportunity to exercise the warrants set forth on your signature page attached hereto (the “Warrants”) and held by you (the “Holder”). The or

May 15, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-284350 PROSPECTUS SUPPLEMENT No. 1 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares This prospectus supplement No. 1 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amen

May 15, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 1 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares This prospectus supplement No. 1 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

May 15, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 1 (To the Prospectus dated May 9, 2025) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 434,901 American Depositary Shares This prospectus supplement No. 1 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, as amended,

May 15, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number 001-37652 Biod

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of pri

May 12, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address o

May 12, 2025 424B3

2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares

Filed Pursuant to Rule 424(b)(3) Registration No. 333-279994 PROSPECTUS 2,486,190,000 Ordinary Shares Representing 248,619 American Depositary Shares This prospectus relates to the resale from time to time, by the selling shareholders identified in this prospectus, of up to an aggregate of 2,486,190,000 ordinary shares, nominal value £0.00005 per share, or Ordinary Shares, of Biodexa Pharmaceutica

May 12, 2025 EX-99.1

Biodexa Receives Orphan Drug Designation in Europe for eRapa in FAP

EXHIBIT 99.1 Biodexa Receives Orphan Drug Designation in Europe for eRapa in FAP May 12, 2025 Biodexa Receives Orphan Drug Designation in Europe for eRapa in FAP New designation follows the U.S. Food and Drug Administration (FDA) Orphan Drug Designation for eRapa in FAP granted in 2019 Company nears start of Registrational Phase 3 study targeted at an addressable market of $7.3Bn Biodexa Pharmaceu

May 12, 2025 424B3

341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares

Filed Pursuant to Rule 424(b)(3) Registration No. 333-284350 PROSPECTUS 341,352,000,000 Ordinary Shares Representing 34,135,200 American Depositary Shares This prospectus relates to the potential offer and sale from time to time by C/M Capital Master Fund, LP, or the Selling Shareholder, of up to 341,352,000,000 of our ordinary shares, nominal value £0.00005 per share, or Ordinary Shares, represen

May 12, 2025 424B3

4,349,010,000 Ordinary Shares Representing 434,901 American Depositary Shares

Filed Pursuant to Rule 424(b)(3) Registration No. 333-281489 PROSPECTUS 4,349,010,000 Ordinary Shares Representing 434,901 American Depositary Shares This prospectus relates to the resale from time to time, by the selling shareholders identified in this prospectus, of up to an aggregate of 4,349,010,000 ordinary shares, nominal value £0.00005 per share, or Ordinary Shares, of Biodexa Pharmaceutica

May 8, 2025 POS AM

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MAY 8, 2025

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MAY 8, 2025 Registration No.

May 8, 2025 POS AM

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MAY 8, 2025

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MAY 8, 2025 Registration No.

May 2, 2025 EX-99.1

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Result of General Meeting

Exhibit 99.1 May 2, 2025 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Result of General Meeting Biodexa Pharmaceuticals PLC, (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs announces that at its General Meeting held at 1.00pm BST today, ordinary resolutions 1 and 2 were passed

May 2, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number 001-37652 Biod

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of pri

April 29, 2025 POS AM

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON APRIL 29, 2025

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON APRIL 29, 2025 Registration No.

April 17, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of April 2025 Commission File Number: 001-3765

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of April 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address

April 17, 2025 EX-99.2

NOTICE OF GENERAL MEETING BIODEXA PHARMACEUTICALS PLC (Incorporated and registered in England and Wales with registered no. 09216368)

Exhibit 99.2 NOTICE OF GENERAL MEETING BIODEXA PHARMACEUTICALS PLC (Incorporated and registered in England and Wales with registered no. 09216368) Notice is hereby given that a general meeting (“GM”) of the members of Biodexa Pharmaceuticals PLC (the “Company”) will be held at 1 Caspian Point, Caspian Way, Cardiff, Wales, CF10 4DQ on 2 May 2025 at 1:00 p.m. to consider and, if thought fit, pass th

April 17, 2025 EX-99.1

Notice of General Meeting

EXHIBIT 99.1 Notice of General Meeting April 17, 2025 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Notice of General Meeting Biodexa Pharmaceuticals PLC, (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs announces a Notice of a General Meeting to be held at the Company’s offices

April 11, 2025 EX-11.1

DATED 14 March 2025 BIODEXA PHARMACEUTICALS PLC INSIDER TRADING/SHARE DEALING CODE

Exhibit 11.1 DATED 14 March 2025 BIODEXA PHARMACEUTICALS PLC INSIDER TRADING/SHARE DEALING CODE BIODEXA PHARMACEUTICALS PLC COMPANY INSIDER TRADING SHARE DEALING CODE (the Code) 1. INTRODUCTION 1.1 Laws of the United Kingdom, the United States and other territories in which the Company operates prohibit dealing in Securities and certain other actions based on inside information. 1.2 If you have an

April 11, 2025 EX-12.1

Certification Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Exhibit 12.1 Certification Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Stephen Stamp, certify that: 1. I have reviewed this annual report on Form 20-F of Biodexa Pharmaceuticals PLC (the “Company”); 2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the c

April 11, 2025 20-F

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 20-F

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 20-F (Mark One) ¨ REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXC

April 11, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of April 2025 Commission File Number 001-37652 Bi

6-K 1 z4102506k.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of April 2025 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United K

April 11, 2025 EX-4.15

Biodexa Pharmaceuticals PLC Promissory Note

Exhibit 4.15 THIS HAS NOT BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE. THIS NOTE HAS BEEN SOLD IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PU

April 11, 2025 EX-13.1

Certification pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Exhibit 13.1 Certification pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 In connection with the Annual Report on Form 20-F of Biodexa Pharmaceuticals PLC (the “Company”) for the year ended December 31, 2024, as filed with the United States Securities and Exchange Commission on the date hereof (the “Report”), the undersigned Stephen Stamp,

April 11, 2025 EX-15.1

The Directors

Exhibit 15.1 The Directors Biodexa Pharmaceuticals plc 1 Caspian Point Caspian Way Cardiff Wales CF10 4DQ DDI: +44 (0)20 7516 2200 Email: [email protected] Date: 10 April 2025 Consent of Independent Registered Public Accounting Firm – Exhibit 15.1 Dear Sir / Madam We consent to the inclusion of our audit report dated April 10, 2025 in the Annual Report on Form 20-F on the consolidated financial

April 11, 2025 EX-99.1

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company” or, together with its subsidiaries, the “Group”) Preliminary Results for the Year Ended 31 December 2024

Exhibit 99.1 April 11, 2025 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company” or, together with its subsidiaries, the “Group”) Preliminary Results for the Year Ended 31 December 2024 Biodexa Pharmaceuticals PLC (Nasdaq: BDRX), an acquisition-focused clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, an

April 11, 2025 EX-2.1

DESCRIPTION OF SECURITIES REGISTERED UNDER SECTION 12 OF THE EXCHANGE ACT

Exhibit 2.1 DESCRIPTION OF SECURITIES REGISTERED UNDER SECTION 12 OF THE EXCHANGE ACT The following description of the securities registered under Section 12 of the Securities Exchange Act of 1934, as amended of Biodexa Pharmaceutucals PLC (“Biodexa,” “we,” “us,” “our” or the “Company”) is a summary of the rights of our issued share capital and certain provisions of our articles of association. Th

April 11, 2025 EX-15.2

30 Old Bailey

Exhibit 15.2 30 Old Bailey London EC4M 7AU Tel: +44 (0)20 7063 4000 forvismazars.com/uk Consent of Independent Registered Public Accounting Firm The Board of Directors of Biodexa Pharmaceuticals PLC, We hereby consent to the incorporation by reference in this Form 20-F (to be filed on or about April 11, 2025) of our audit report dated April 18, 2024 with respect to the consolidated balance sheets

March 10, 2025 EX-99.1

Biodexa Announces Successful Outcome of a Type C Meeting with FDA Regarding the Phase 3 Program for eRapa in FAP

EXHIBIT 99.1 Biodexa Announces Successful Outcome of a Type C Meeting with FDA Regarding the Phase 3 Program for eRapa in FAP March 10, 2025 Biodexa Announces Successful Outcome of a Type C Meeting with FDA Regarding the Phase 3 Program for eRapa in FAP Clears the way to finalize Phase 3 protocol and recruit sites for U.S. Phase 3 substantially funded by $17.0 million CPRIT grant and $8.5 million

March 10, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2025 Commission File Number: 001-3765

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address

March 6, 2025 EX-99.1

Biodexa Announces Appointment of Precision for Medicine LLC as CRO for European Component of Phase 3 Study of eRapa in FAP

EXHIBIT 99.1 Biodexa Announces Appointment of Precision for Medicine LLC as CRO for European Component of Phase 3 Study of eRapa in FAP March 6, 2025 Biodexa Announces Appointment of Precision for Medicine LLC as CRO for European Component of Phase 3 Study of eRapa in FAP Biodexa is finalizing plans to initiate an international Phase 3 registrational study of eRapa in Familial Adenomatous Polyposi

March 6, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2025 Commission File Number: 001-3765

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address

February 24, 2025 EX-99.1

Biodexa Announces Allowance of U.S. Patent Covering Oral Rapamycin Nanoparticle Preparations (“eRapa”) and Use

EXHIBIT 99.1 Biodexa Announces Allowance of U.S. Patent Covering Oral Rapamycin Nanoparticle Preparations (“eRapa”) and Use February 24, 2025 Biodexa Announces Allowance of U.S. Patent Covering Oral Rapamycin Nanoparticle Preparations (“eRapa”) and Use Biodexa plans to initiate a Phase 3 registrational study of eRapa in Familial Adenomatous Polyposis (FAP) next quarter Biodexa Pharmaceuticals PLC

February 24, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2025 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Addr

February 18, 2025 EX-99.1

BDRX / Biodexa Pharmaceuticals Plc - Depositary Receipt (Common Stock) / C/M CAPITAL PARTNERS, LP - JOINT FILING AGREEMENT JOINT ACQUISITION STATEMENT PURSUANT TO RULE 13d-1(k)

EXHIBIT 99.1 JOINT ACQUISITION STATEMENT PURSUANT TO RULE 13d-1(k) The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint acquisition statements. The unders

February 13, 2025 EX-99.1

Biodexa Pharmaceuticals PLC to Present at the Emerging Growth Conference on February 19, 2025

EXHIBIT 99.1 Biodexa Pharmaceuticals PLC to Present at the Emerging Growth Conference on February 19, 2025 February 13, 2025 Biodexa Pharmaceuticals PLC to Present at the Emerging Growth Conference on February 19, 2025 Biodexa Pharmaceuticals PLC invites individual and institutional investors as well as advisors and analysts, to attend its real-time, interactive presentation at the Emerging Growth

February 13, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2025 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Addr

February 10, 2025 EX-99.1

Biodexa Receives US FDA Fast Track Designation for eRapa in Familial Adenomatous Polyposis

EXHIBIT 99.1 Biodexa Receives US FDA Fast Track Designation for eRapa in Familial Adenomatous Polyposis February 10, 2025 Biodexa Receives US FDA Fast Track Designation for eRapa in Familial Adenomatous Polyposis Underscores unmet need for a therapeutic alternative with the potential to delay or prevent surgical removal of the colon and/or rectum Biodexa Pharmaceuticals PLC (“Biodexa” or “the Comp

February 10, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2025 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Addr

January 28, 2025 424B3

358,750,000,000 Ordinary Shares Representing 35,875,000 American Depositary Shares

Filed Pursuant to Rule 424(b)(3) Registration No. 333-284350 PROSPECTUS 358,750,000,000 Ordinary Shares Representing 35,875,000 American Depositary Shares This prospectus relates to the potential offer and sale from time to time by C/M Capital Master Fund, LP, or the Selling Shareholder, of up to 358,750,000,000 of our ordinary shares, nominal value £0.00005 per share, or Ordinary Shares, represen

January 23, 2025 CORRESP

Biodexa Pharmaceuticals PLC 1 Caspian Point Caspian Way Cardiff, CF10 4DQ United Kingdom

Biodexa Pharmaceuticals PLC 1 Caspian Point Caspian Way Cardiff, CF10 4DQ United Kingdom January 23, 2025 VIA EDGAR Securities and Exchange Commission Division of Corporate Finance 100 F Street, N.

January 22, 2025 EX-99.1

Biodexa Strengthens Management Team - Appointment of Dr Gary A. Shangold as Chief Medical Officer

EXHIBIT 99.1 Biodexa Strengthens Management Team - Appointment of Dr Gary A. Shangold as Chief Medical Officer January 22, 2025 Biodexa Strengthens Management Team Appointment of Dr Gary A. Shangold as Chief Medical Officer Biodexa Pharmaceuticals PLC (“Biodexa” or “the Company”), (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatm

January 22, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of January 2025 Commission File Number: 001-37

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of January 2025 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Addre

January 21, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 13 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to p

January 21, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

424B3 1 b424b3ps10279994.htm PROSPECTUS SUPPLEMENT NO. 10 Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 10 (To the Prospectus dated June 14, 2024) BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus supplement No. 10 (the “Prospectus Supplement”) amends and supplements our prospectus c

January 21, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 8 (To the Prospectus dated August 12, 2024) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares This prospectus supplement No. 8 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effec

January 21, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 12 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 12 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registrati

January 21, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 19 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 19 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration Stat

January 21, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 19 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 19 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

January 21, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 19 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 19 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

January 17, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of January 2025 Commission File Number 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of January 2025 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of

January 17, 2025 EX-FILING FEES

CALCULATION OF FILING FEE TABLES Biodexa Pharmaceuticals PLC Table 1: Newly Registered and Carry Forward Securities

Ex-Filing Fees CALCULATION OF FILING FEE TABLES F-1 Biodexa Pharmaceuticals PLC Table 1: Newly Registered and Carry Forward Securities Line Item Type Security Type Security Class Title Notes Fee Calculation Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Newly Registered Securities Fees to be Paid Equity Ordinary Shares, nominal value £0.

January 17, 2025 EX-21.1

EX-21.1

Exhibit 21.1 Subsidiaries Country of Incorporation Voting Interest Subsidiaries of Biodexa Pharmaceuticals PLC Biodexa Pharmaceuticals (Wales) Limited England and Wales 100% Biodexa Ltd England and Wales 100% Haaland UK Limited (2) England and Wales 100% Subsidiaries of Biodexa Ltd Pharmida AG (2) Switzerland 100% (1) Dormant entities.

January 17, 2025 EX-4.1

DESCRIPTION OF SECURITIES REGISTERED UNDER SECTION 12 OF THE EXCHANGE ACT

Exhibit 4.1 DESCRIPTION OF SECURITIES REGISTERED UNDER SECTION 12 OF THE EXCHANGE ACT The following describes our issued share capital, summarizes the material provisions of our articles of association and highlights certain differences in corporate law in the United Kingdom and the United States. Please note that this summary is not intended to be exhaustive. For further information please refer

January 17, 2025 EX-10.1

SECURITIES PURCHASE AGREEMENT

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT THIS SECURITIES PURCHASE AGREEMENT (the “Agreement”), dated as of January 17, 2025 (the “Execution Date”), by and between BIODEXA PHARMACEUTICALS PLC, a company incorporated under the laws of England and Wales (the “Company”), and C/M CAPITAL MASTER FUND, LP, a Delaware limited partnership (the “Investor”). WHEREAS: Subject to the terms and conditions set

January 17, 2025 EX-10.2

REGISTRATION RIGHTS AGREEMENT

Exhibit 10.2 REGISTRATION RIGHTS AGREEMENT THIS REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of January 17, 2025 (the “Execution Date”), is entered into by and between BIODEXA PHARMACEUTICALS PLC, a company incorporated under the laws of England and Wales (the “Company”), and C/M CAPITAL MASTER FUND, LP, a Delaware limited partnership (together with its permitted assigns, the “Buyer”

January 17, 2025 F-1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON JANUARY 17, 2025

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON JANUARY 17, 2025 Registration No.

January 8, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 18 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 18 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

January 8, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 18 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 18 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

January 8, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 12 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to p

January 8, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 9 (To the Prospectus dated June 14, 2024) BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus supplement No. 9 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effectiv

January 8, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 18 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 18 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration Stat

January 8, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 11 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 11 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registrati

January 8, 2025 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 7 (To the Prospectus dated August 12, 2024) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares This prospectus supplement No. 7 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effec

December 27, 2024 EX-10.1

Biodexa Pharmaceuticals PLC Promissory Note

Exhibit 10.1 THIS HAS NOT BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE. THIS NOTE HAS BEEN SOLD IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PU

December 27, 2024 EX-1.1

BIODEXA PHARMACEUTICALS PLC (registered number 09216368) ARTICLES OF ASSOCIATION 8 Clifford Street London W1S 2LQ T: 020 7851 6000 F: 020 7851 6100 Table of Contents

Exhibit 1.1 BIODEXA PHARMACEUTICALS PLC (registered number 09216368) ARTICLES OF ASSOCIATION TWM/031674.0002 8 Clifford Street London W1S 2LQ www.brownrudnick.com T: 020 7851 6000 F: 020 7851 6100 Table of Contents PRELIMINARY 1 1 DEFINITIONS 1 2 LIABILITY OF MEMBERS 5 3 FORM OF RESOLUTION 5 4 EXCLUSION OF MODEL ARTICLES (AND ANY OTHER PRESCRIBED REGULATIONS) 5 5 REGISTERED OFFICE 5 SHARE CAPITAL

December 27, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2024 Commission File Number 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address o

December 4, 2024 EX-99.1

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Result of General Meeting

Exhibit 99.1 November 22, 2024 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Result of General Meeting Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (NASDAQ: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs announces, announces that at its General Meeting held earlier today, b

December 4, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2024 Commission File Number 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address o

November 20, 2024 SC 13G/A

BDRX / Biodexa Pharmaceuticals Plc - Depositary Receipt (Common Stock) / Brio Capital Master Fund Ltd. - AMENDMENT NO. 1 TO SCHEDULE 13G Passive Investment

SC 13G/A 1 ea0221977-13ga1briobio.htm AMENDMENT NO. 1 TO SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G (Amendment No. 1) UNDER THE SECURITIES EXCHANGE ACT OF 1934* BIODEXA PHARMACEUTICALS PLC (Name of Issuer) AMERICAN DEPOSITORY SHARES** (Title of Class of Securities) 59564R708*** (CUSIP Number) November 14, 2024 (Date of Event Which Requires Fil

November 14, 2024 SC 13G/A

BDRX / Biodexa Pharmaceuticals Plc - Depositary Receipt (Common Stock) / Iroquois Capital Management, LLC Passive Investment

SC 13G/A 1 c110565sc13ga.htm SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2. (Amendment No. 1)* Biodexa Pharmaceuticals PLC (Name of Issuer) American Depositary Shares, each representing 400 Ordinary Shares (Title of Clas

November 12, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 10 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 10 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registrati

November 12, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 11 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to p

November 12, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address o

November 12, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 6 (To the Prospectus dated August 12, 2024) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares This prospectus supplement No. 6 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effec

November 12, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 17 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 17 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

November 12, 2024 EX-99.1

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Regains Compliance For Continued Listing on Nasdaq

Exhibit 99.1 November 12, 2024 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Regains Compliance For Continued Listing on Nasdaq Biodexa Pharmaceuticals PLC, (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs announces that the Company has been formally notified that the Nasdaq Hea

November 12, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 17 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 17 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration Stat

November 12, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 17 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 17 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

November 12, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 8 (To the Prospectus dated June 14, 2024) BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus supplement No. 8 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effectiv

November 12, 2024 SC 13G/A

BDRX / Biodexa Pharmaceuticals Plc - Depositary Receipt (Common Stock) / Bigger Capital, LLC Passive Investment

SC 13G/A 1 sc13ga110022bdrx11122024.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. 1)1 Biodexa Pharmaceuticals PLC (Name of Issuer) Ordinary Shares, Nominal Value $.001 per share (Title

November 7, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Addr

November 7, 2024 SC 13G/A

BDRX / Biodexa Pharmaceuticals Plc - Depositary Receipt (Common Stock) / Cavalry Fund I LP Passive Investment

SC 13G/A 1 p24-3286sc13ga.htm SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 2)* Biodexa Pharmaceuticals PLC (Name of Issuer) Ordinary shares, nominal value £0.001 per share (Title of Class of Securities) 59564R708** (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the

November 7, 2024 EX-99.1

Notice of General Meeting

EXHIBIT 99.1 Notice of General Meeting November 7, 2024 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Notice of General Meeting Biodexa Pharmaceuticals PLC, (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs announces a Notice of a General Meeting to be held at the Company’s offic

November 5, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 16 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 16 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration Stat

November 5, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 16 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 16 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

November 5, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 9 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 9 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration

November 5, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 10 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to p

November 5, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 16 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 16 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

November 5, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 7 (To the Prospectus dated June 14, 2024) BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus supplement No. 7 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effectiv

November 5, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 5 (To the Prospectus dated August 12, 2024) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares This prospectus supplement No. 5 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effec

November 1, 2024 EX-16.1

Securities and Exchange Commission

Exhibit 16.1 30 Old Bailey London EC4M 7AU Tel: +44 (0)20 7063 4000 forvismazars.com/uk Private & Confidential Securities and Exchange Commission 100 F Street NE Washington D.C. 20549 United States of America Date: 1 November 2024 Ladies and Gentlemen, We have been furnished with a copy of the form 6-K to be filed by our former client, Biodexa Pharmaceuticals plc, to satisfy its reporting obligati

November 1, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address o

October 16, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 15 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 15 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration Stat

October 16, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 6 (To the Prospectus dated June 14, 2024) BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus supplement No. 6 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effectiv

October 16, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 15 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 15 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

October 16, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 8 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 8 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration

October 16, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 9 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to pu

October 16, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 15 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 15 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

October 16, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 4 (To the Prospectus dated August 12, 2024) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares This prospectus supplement No. 4 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effec

October 15, 2024 EX-99.1

Biodexa Announces Successful Appeal of Nasdaq Delisting

Exhibit 99.1 October 15, 2024 Biodexa Announces Successful Appeal of Nasdaq Delisting Biodexa Pharmaceuticals PLC. (the “Company”) (Nasdaq: BDRX), an acquisition-focused clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, announced today that a Nasdaq Hearings Panel (the “Panel”) has granted the Company’s req

October 15, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2024 Commission File Number 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of

October 4, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2024 Commission File Number: 001-37

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2024 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Addre

October 4, 2024 EX-99.1

Biodexa Provides Update on Progression Free and Overall Survival in Phase 1 Study of MTX110 in Recurrent Glioblastoma

EXHIBIT 99.1 Biodexa Provides Update on Progression Free and Overall Survival in Phase 1 Study of MTX110 in Recurrent Glioblastoma October 4, 2024 Biodexa Provides Update on Progression Free and Overall Survival in Phase 1 Study of MTX110 in Recurrent Glioblastoma Cohort A Data on Overall Survival Compare Favorably with Published Survival Rates Results Build on MTX110’s Performance in Two Phase 1

September 27, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 14 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 14 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration Stat

September 27, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 14 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 14 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

September 27, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 14 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 14 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

September 27, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 7 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 7 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration

September 27, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 5 (To the Prospectus dated June 14, 2024) BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus supplement No. 5 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effectiv

September 27, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 8 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to pu

September 27, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 3 (To the Prospectus dated August 12, 2024) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares This prospectus supplement No. 3 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effec

September 26, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 June 30,2024 For the month of September 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United King

September 20, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 4 (To the Prospectus dated June 14, 2024) BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus supplement No. 4 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effectiv

September 20, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 13 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 13 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration Stat

September 20, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 13 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 13 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

September 20, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 7 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to pu

September 20, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 6 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 6 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration

September 20, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 13 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 13 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

September 20, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 2 (To the Prospectus dated August 12, 2024) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares This prospectus supplement No. 2 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effec

September 19, 2024 EX-99.1

ADR Ratio Change

EXHIBIT 99.1 ADR Ratio Change September 19, 2024 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) ADR Ratio Change Biodexa Pharmaceuticals PLC (Nasdaq: BDRX), an acquisition-focused clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, today announces a ratio change on its American Depositary Receipts (

September 19, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2024 Commission File Number: 001-

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2024 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Add

September 16, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2024 Commission File Number: 001-

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2024 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Add

September 16, 2024 EX-99.1

Announces Payment of $3.0MM Final Match Payment Enabling Access to Remainder of $17.0MM CPRIT Grant

EXHIBIT 99.1 Announces Payment of $3.0MM Final Match Payment Enabling Access to Remainder of $17.0MM CPRIT Grant September 16, 2024 Biodexa Pharmaceuticals PLC Announces Payment of $3.0MM Final Match Payment Enabling Access to Remainder of $17.0MM CPRIT Grant Funds to Advance Development of Phase 3 Asset Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (Nasdaq: BDRX), an acquisition-focuse

September 9, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 12 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 12 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

September 9, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-281489 PROSPECTUS SUPPLEMENT No. 1 (To the Prospectus dated August 12, 2024) BIODEXA PHARMACEUTICALS PLC 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares This prospectus supplement No. 1 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effec

September 9, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 5 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 5 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration

September 9, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 3 (To the Prospectus dated June 14, 2024) BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus supplement No. 3 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effectiv

September 9, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 12 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 12 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

September 9, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 6 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to pu

September 9, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 12 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 12 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration Stat

August 30, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of August 2024 Commission File Number 001-37652 B

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of August 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of

August 30, 2024 EX-99.1

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Receipt of Nasdaq Delisting Determination Plans to Appeal

Exhibit 99.1 August 30, 2024 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Receipt of Nasdaq Delisting Determination Plans to Appeal Biodexa Pharmaceuticals PLC (Nasdaq: BDRX), an acquisition-focused clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, announced today that on August 27, 2024, it rec

August 20, 2024 424B3

4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares

Filed Pursuant to Rule 424(b)(3) Registration No, 333-281489 PROSPECTUS 4,349,102,800 Ordinary Shares Representing 10,872,757 American Depositary Shares This prospectus relates to the resale from time to time, by the selling shareholders identified in this prospectus, of up to an aggregate of 4,349,102,800 ordinary shares, nominal value £0.

August 15, 2024 CORRESP

Biodexa Pharmaceuticals PLC 1 Caspian Point Caspian Way Cardiff, CF10 4DQ United Kingdom

Biodexa Pharmaceuticals PLC 1 Caspian Point Caspian Way Cardiff, CF10 4DQ United Kingdom August 15, 2024 VIA EDGAR Securities and Exchange Commission Division of Corporate Finance 100 F Street, N.

August 12, 2024 F-1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON AUGUST 12, 2024

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON AUGUST 12, 2024 Registration No.

August 12, 2024 EX-FILING FEES

Calculation of Filing Fee Tables FORM F-1 (Form Type) Biodexa Pharmaceuticals PLC (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities

Exhibit 107 Calculation of Filing Fee Tables FORM F-1 …………... (Form Type) Biodexa Pharmaceuticals PLC ……………………………………………………….. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title(1) Fee Calculation or Carry Forward Rule Amount Registered(2) Proposed Maximum Offering Price Per Ordinary Share Maximum Aggregate Offering Price(3

August 8, 2024 SC 13G

BDRX / Biodexa Pharmaceuticals Plc - Depositary Receipt (Common Stock) / Iroquois Capital Management, LLC Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2. (Amendment No. )* Biodexa Pharmaceuticals PLC (Name of Issuer) American Depositary Shares, each representing 400 Ordinary Shares (Title of Class of Securities) 59564R708** (

July 23, 2024 EX-99.1

Biodexa Pharmaceuticals PLC Announces Closing of $5.0 Million Registered Direct Offering and Concurrent Private Placement

Exhibit 99.1 July 23, 2024 Biodexa Pharmaceuticals PLC Announces Closing of $5.0 Million Registered Direct Offering and Concurrent Private Placement Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (Nasdaq: BDRX), an acquisition-focused clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, today announc

July 23, 2024 SC 13G

BDRX / Biodexa Pharmaceuticals Plc - Depositary Receipt (Common Stock) / Brio Capital Master Fund Ltd. - SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934* BIODEXA PHARMACEUTICALS PLC (Name of Issuer) AMERICAN DEPOSITORY SHARES** (Title of Class of Securities) 59564R708*** (CUSIP Number) July 15, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which thi

July 23, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number 001-37652 Bio

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of pr

July 23, 2024 EX-99.1

JOINT FILING AGREEMENT

EXHIBIT 1 JOINT FILING AGREEMENT Each of the undersigned agrees that (i) the statement on Schedule 13G relating to the Common Stock of BIODEXA PHARMACEUTICALS PLC has been adopted and filed on behalf of each of them, (ii) all future amendments to such statement on Schedule 13G will, unless written notice to the contrary is delivered as described below, be jointly filed on behalf of each of them and (iii) the provisions of Rule 13d-1(k)(1) under the Securities Exchange Act of 1934 shall apply to each of them.

July 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

424B3 1 p722246424b3.htm Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 5 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,61

July 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

424B3 1 b722244424b3.htm Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 11 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 11 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No

July 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

424B3 1 o722244424b3.htm Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 11 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 11 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to

July 22, 2024 424B5

BIODEXA PHARMACEUTICALS PLC 5,050,808 American Depositary Shares Representing 2,020,323,200 Ordinary Shares 278,975 Pre-Funded Warrants to purchase 278,975 American Depositary Shares Representing 111,590,000 Ordinary Shares

Filed pursuant to Rule 424(b)(5) Registration No.: 333-267932 PROSPECTUS SUPPLEMENT (to Prospectus dated October 26, 2022) BIODEXA PHARMACEUTICALS PLC 5,050,808 American Depositary Shares Representing 2,020,323,200 Ordinary Shares 278,975 Pre-Funded Warrants to purchase 278,975 American Depositary Shares Representing 111,590,000 Ordinary Shares We are offering 5,050,808 of our American Depositary

July 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 2 (To the Prospectus dated June 14, 2024) BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus supplement No. 2 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effectiv

July 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

424B3 1 o722245424b3.htm Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 4 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 4 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendm

July 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 11 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 11 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration Stat

July 19, 2024 6-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K/A REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number 001-37652 B

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K/A REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address of

July 19, 2024 EX-4.1

SERIES J WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES Biodexa Pharmaceuticals Plc

Exhibit 4.1 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED, SOLD, PLEDGED, OR OTHERWISE DISTRIBUTED OR TRA

July 19, 2024 EX-4.3

PLACEMENT AGENT WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES Biodexa Pharmaceuticals Plc

Exhibit 4.3 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED, SOLD, PLEDGED, OR OTHERWISE DISTRIBUTED OR TRA

July 19, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number 001-37652 Bio

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address of p

July 19, 2024 EX-4.2

SERIES K WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES Biodexa Pharmaceuticals Plc

Exhibit 4.2 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED, SOLD, PLEDGED, OR OTHERWISE DISTRIBUTED OR TRA

July 19, 2024 EX-10.1

SECURITIES PURCHASE AGREEMENT

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”), dated as of July 18, 2024, is between Biodexa Pharmaceuticals Plc, a public limited company organized under the laws of England and Wales (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purcha

July 19, 2024 EX-99.1

Biodexa Pharmaceuticals PLC Announces Pricing of $5.0 Million Registered Direct Offering and Concurrent Private Placement

Exhibit 99.1 July 19, 2024 Biodexa Pharmaceuticals PLC Announces Pricing of $5.0 Million Registered Direct Offering and Concurrent Private Placement Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (Nasdaq: BDRX), an acquisition-focused clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, today announc

July 19, 2024 EX-4.4

PRE-FUNDED WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES Biodexa Pharmaceuticals Plc

Exhibit 4.4 PRE-FUNDED WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES Biodexa Pharmaceuticals Plc Warrant ADSs: [] Initial Exercise Date: [], 2024 THIS PRE-FUNDED WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES (the “Warrant”) certifies that, for value received, [] or its assigns (the “Holder”) is entitled, upon the terms and subject to

July 19, 2024 EX-10.2

PLACEMENT AGENCY AGREEMENT

Exhibit 10.2 PLACEMENT AGENCY AGREEMENT July 18, 2024 Ladenburg Thalmann & Co. Inc. 640 Fifth Avenue, 4th Floor New York, New York 10019 Ladies and Gentlemen: Introduction. Subject to the terms and conditions herein (this “Agreement”), Biodexa Pharmaceuticals Plc, a public limited company organized under the laws of England and Wales (the “Company”), hereby agrees to sell up to an aggregate of $5,

July 16, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address

July 16, 2024 EX-99.1

Biodexa Announces Phase 2a Study of Tolimidone in Type 1 Diabetes Approved by Health Canada

EdgarFiling EXHIBIT 99.1 Biodexa Announces Phase 2a Study of Tolimidone in Type 1 Diabetes Approved by Health Canada July 16, 2024 Biodexa Announces Phase 2a Study of Tolimidone in Type 1 Diabetes Approved by Health Canada Biodexa Pharmaceuticals PLC (“Biodexa” or “the Company”), (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatme

July 11, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 3 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 3 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration

July 11, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 4 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to pu

July 11, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 10 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 10 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

July 11, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-279994 PROSPECTUS SUPPLEMENT No. 1 (To the Prospectus dated June 14, 2024) BIODEXA PHARMACEUTICALS PLC 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus supplement No. 1 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Registration Statement on Form F-1, effectiv

July 11, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 10 (to Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 10 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

July 11, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 10 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 10 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration Stat

July 5, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number 001-37652 Bio

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of pr

July 2, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address

July 2, 2024 EX-99.1

Positive Phase 1 Clinical Data of MTX110 in DMG Brain Cancer Demonstrating Increased Survival Presented at ISPNO 2024

EXHIBIT 99.1 Positive Phase 1 Clinical Data of MTX110 in DMG Brain Cancer Demonstrating Increased Survival Presented at ISPNO 2024 July 2, 2024 Biodexa Pharmaceuticals PLC Positive Phase 1 Clinical Data of MTX110 in DMG Brain Cancer Demonstrating Increased Survival Presented at ISPNO 2024 After Only Two Infusions and Two Patients at Optimal Dose, Median Overall Survival Across all Patients was 16.

June 24, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2024 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2024 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address

June 24, 2024 EX-99.1

Biodexa Announces Positive Phase 2 Clinical Trial Results of eRapa™ at 12 months in Familial Adenomatous Polyposis (FAP)

EXHIBIT 99.1 Biodexa Announces Positive Phase 2 Clinical Trial Results of eRapa™ at 12 months in Familial Adenomatous Polyposis (FAP) June 24, 2024 Biodexa Pharmaceuticals PLC Biodexa Announces Positive Phase 2 Clinical Trial Results of eRapa™ at 12 months in Familial Adenomatous Polyposis (FAP) Overall 75% Non-progression Rate at 12 Months Median Decrease in Overall Polyp Burden at 12 Months of 1

June 17, 2024 424B3

2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares

Filed Pursuant to Rule 424(b)(3) Registration No. 333-279994 PROSPECTUS 2,486,270,400 Ordinary Shares Representing 6,215,676 American Depositary Shares This prospectus relates to the resale from time to time, by the selling shareholders identified in this prospectus, of up to an aggregate of 2,486,270,400 ordinary shares, nominal value £0.001 per share, or Ordinary Shares, of Biodexa Pharmaceutica

June 13, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2024 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2024 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address

June 13, 2024 EX-99.1

Results of Annual General Meeting

EXHIBIT 99.1 Results of Annual General Meeting 13 June 2024 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Results of Annual General Meeting Biodexa Pharmaceuticals PLC (NASDAQ: BDRX), an acquisition-focused clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, announces that at its Annual General Mee

June 11, 2024 CORRESP

Biodexa Pharmaceuticals PLC 1 Caspian Point Caspian Way Cardiff, CF10 4DQ United Kingdom

Biodexa Pharmaceuticals PLC 1 Caspian Point Caspian Way Cardiff, CF10 4DQ United Kingdom June 11, 2024 VIA EDGAR Securities and Exchange Commission Division of Corporate Finance 100 F Street, N.

June 6, 2024 F-1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON JUNE 6, 2024

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON JUNE 6, 2024 Registration No.

June 6, 2024 EX-FILING FEES

Calculation of Filing Fee Tables FORM F-1 (Form Type) Biodexa Pharmaceuticals PLC (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities

Exhibit 107 Calculation of Filing Fee Tables FORM F-1 …………... (Form Type) Biodexa Pharmaceuticals PLC ……………………………………………………….. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title(1) Fee Calculation or Carry Forward Rule Amount Registered(2) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price(3) Fee Rate

May 29, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 9 (To the Prospectus dated June 1, 2023) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 9 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration State

May 29, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 9 (to Prospectus dated June 26, 2023) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 9 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

May 29, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 3 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to pu

May 29, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 9 (to Prospectus dated June 28, 2023) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 9 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

May 29, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 2 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 2 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration

May 28, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number 001-37652 Biod

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of pri

May 28, 2024 EX-4.1

SERIES G WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES Biodexa Pharmaceuticals Plc

Exhibit 4.1 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED, SOLD, PLEDGED, OR OTHERWISE DISTRIBUTED OR TRA

May 28, 2024 EX-4.2

SERIES H WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES Biodexa Pharmaceuticals Plc

Exhibit 4.2 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED, SOLD, PLEDGED, OR OTHERWISE DISTRIBUTED OR TRA

May 28, 2024 EX-4.3

PLACEMENT AGENT WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES Biodexa Pharmaceuticals Plc

Exhibit 4.3 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED, SOLD, PLEDGED, OR OTHERWISE DISTRIBUTED OR TRA

May 22, 2024 EX-4.1

SERIES G WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES Biodexa Pharmaceuticals Plc

Exhibit 4.1 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED, SOLD, PLEDGED, OR OTHERWISE DISTRIBUTED OR TRA

May 22, 2024 EX-99.1

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Biodexa Announces $7 Million of Gross Proceeds from Warrant Exercises Proceeds Cover Year 1 eRapa Phase 3 Obligations, Unlocking Twice that Amount in Non-dilutive Grant Funding

Exhibit 99.1 May 22, 2024 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Biodexa Announces $7 Million of Gross Proceeds from Warrant Exercises Proceeds Cover Year 1 eRapa Phase 3 Obligations, Unlocking Twice that Amount in Non-dilutive Grant Funding Biodexa Pharmaceuticals PLC, (Nasdaq: BDRX), an acquisition-focused clinical stage biopharmaceutical company developing a pipeline of innova

May 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-278040 PROSPECTUS SUPPLEMENT No. 1 (To the Prospectus dated May 2, 2024) BIODEXA PHARMACEUTICALS PLC 1,192,023,200 Ordinary Shares Representing 2,980,058 American Depositary Shares This prospectus supplement No. 1 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration

May 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-270353 PROSPECTUS SUPPLEMENT No. 8 (To the Prospectus dated June 1, 2023) BIODEXA PHARMACEUTICALS PLC 8,203,200 Ordinary Shares Representing 20,508 American Depositary Shares This prospectus supplement No. 8 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 3 to Registration State

May 22, 2024 EX-4.2

SERIES H WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES Biodexa Pharmaceuticals Plc

Exhibit 4.2 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED, SOLD, PLEDGED, OR OTHERWISE DISTRIBUTED OR TRA

May 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 1 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to pu

May 22, 2024 EX-10.1

Annex A – Representations and Warranties

Exhibit 10.1 May 22, 2024 [Name and address of warrant holder] Re: Reprice and Reload Offer of Series G and Series H Warrants To Whom It May Concern: Biodexa Pharmaceuticals Plc, a public limited company organized under the laws of England and Wales (the “Company”), is pleased to offer to you the opportunity to exercise all of the Series G Warrants and/or Series H Warrants set forth on your signat

May 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-240984 PROSPECTUS SUPPLEMENT No. 8 (to Prospectus dated June 26, 2023) BIODEXA PHARMACEUTICALS PLC 492,400 Ordinary Shares Representing 1,230 American Depositary Shares This prospectus supplement No. 8 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 4 to Registration Statement o

May 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series

Filed pursuant to Rule 424(b)(3) Registration No.: 333-274895 PROSPECTUS SUPPLEMENT No. 2 (To the Prospectus dated December 18, 2023) BIODEXA PHARMACEUTICALS PLC 697,614 Class A Units consisting of 697,614 American Depositary Shares Representing Ordinary Shares, 697,614 Series E Warrants to purchase 697,614 American Depositary Shares Representing Ordinary shares and 697,614 Series F Warrants to pu

May 22, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number 001-37652 Biod

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant’s name into English) 1 Caspian Point, Caspian Way Cardiff, CF10 4DQ, United Kingdom (Address of pri

May 22, 2024 424B3

BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares

Filed pursuant to Rule 424(b)(3) Registration No.: 333-272693 PROSPECTUS SUPPLEMENT No. 8 (to Prospectus dated June 28, 2023) BIODEXA PHARMACEUTICALS PLC 115,102,400 Ordinary Shares Representing 287,756 American Depositary Shares This prospectus supplement No. 8 (the “Prospectus Supplement”) amends and supplements our prospectus contained in our Post-Effective Amendment No. 1 to Registration State

May 21, 2024 EX-99.1

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Positive Statistically Significant Phase 2 Clinical Trial Results of Biodexa’s Newly-licensed eRapa™ in Familial Adenomatous Polyposis (FAP) Scheduled for Presentation at the 2024 Digestive Dis

EXHIBIT 99.1 May 21, 2024 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Positive Statistically Significant Phase 2 Clinical Trial Results of Biodexa’s Newly-licensed eRapa™ in Familial Adenomatous Polyposis (FAP) Scheduled for Presentation at the 2024 Digestive Disease Week Annual Meeting Overall 83% non-progression rate at 6 Months Statistically Significant decrease in overall mean pol

May 21, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address o

May 15, 2024 EX-99.1

Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Posting of Annual Report & Notice of AGM Total Voting Rights

EXHIBIT 99.1 May 15, 2024 Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) Posting of Annual Report & Notice of AGM Total Voting Rights Biodexa Pharmaceuticals PLC (NASDAQ: BDRX), a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, announces that its Notice of Annual General Meeting (“AGM”) was post

May 15, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-37652

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-37652 Biodexa Pharmaceuticals PLC (Translation of registrant's name into English) 1 Caspian Point, Caspian Way, Cardiff, CF10 4DQ, United Kingdom (Address o

May 15, 2024 EX-99.4

FOR AGAINST WITHHELD FOR AGAINST WITHHELD Res 1. Res 5. Res 2. Res 6. Res 3. Res 7. Res 4. Res 8. BIODEXA PHARMACEUTICALS PLC TO THE REGISTERED HOLDERS OF AMERICAN DEPOSITARY RECEIPTS ("ADRs") REPRESENTING ORDINARY SHARES OF BIODEXA PHARMACEUTICALS P

Exhibit 99.4 FOR AGAINST WITHHELD FOR AGAINST WITHHELD Res 1. Res 5. Res 2. Res 6. Res 3. Res 7. Res 4. Res 8. BIODEXA PHARMACEUTICALS PLC TO THE REGISTERED HOLDERS OF AMERICAN DEPOSITARY RECEIPTS ("ADRs") REPRESENTING ORDINARY SHARES OF BIODEXA PHARMACEUTICALS PLC Sign below Date: Please sign this Voting Instruction Card exactly as your name(s) appear(s) on the face of this card and on the books

May 15, 2024 EX-99.2

NOTICE OF ANNUAL GENERAL MEETINGBIODEXA PHARMACEUTICALS PLC(Incorporated and registered in England and Wales with registered no. 09216368)Notice is hereby given that an Annual General Meeting ("AGM") of the members of Biodexa Pharmaceuticals PLC (the

Exhibit 99.2 NOTICE OF ANNUAL GENERAL MEETINGBIODEXA PHARMACEUTICALS PLC(Incorporated and registered in England and Wales with registered no. 09216368)Notice is hereby given that an Annual General Meeting ("AGM") of the members of Biodexa Pharmaceuticals PLC (the "Company") will be held at 1 Caspian Point, Caspian Way, Cardiff, Wales, CF10 4DQ on 13 June 2024 at 12:00 BST to consider and, if thoug

May 15, 2024 EX-99.1

Biodexa Pharmaceuticals PLC?Annual Report and Accounts 2023Biodexa Pharmaceuticals PLCAnnual Report and Accounts 2023

Exhibit 99.1 Biodexa Pharmaceuticals PLC?Annual Report and Accounts 2023Biodexa Pharmaceuticals PLCAnnual Report and Accounts 2023 Biodexa is a clinical-stage biotech company developing a pipeline of innovative products for the treatment of diseases with high unmet medical needsContentsPageStrategic ReportStrategy 01Business Model 02Clinical Stage Assets 02Chief Executive's Review 04Financial Revi

May 15, 2024 EX-99.3

If you are planning to attend the Annual General Meeting, please tick the following box:>123-0Resolutions (*Special Resolution)FORM OF PROXYBiodexa Pharmaceuticals PLC(a company incorporated in England and Wales under the Companies Act 2006 with comp

Exhibit 99.3 If you are planning to attend the Annual General Meeting, please tick the following box:>123-0Resolutions (*Special Resolution)FORM OF PROXYBiodexa Pharmaceuticals PLC(a company incorporated in England and Wales under the Companies Act 2006 with company number 09216368)I?We being (a) member(s) of the Company and entitled to vote at the AnnualGeneral Meeting, hereby appoint(Please only

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