| Insideraktier | 41 783 886 shares |
Insider Sentiment Score
Insider sentiment score hittar de företag som köps av foretagsinsynspersoner.
Det är resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av insiderackumulation. Poängmodellen använder en kombination av nettoantalet insiders som köpt de föregående 90 dagarna, det totala antalet aktier som köpts i procent av aktiekapitalet och det totala antalet aktier som ägs av insiders. Siffran sträcker sig från 0 till 100, med högre siffror som indikerar en högre nivå av ackumulering för sina kamrater, och 50 är genomsnittet.
Uppdateringsfrekvens: Dagligen
Se Insiders Top Picks, som ger en lista över företag med högsta insiderackumulation.
Office Sentiment Score
Officersentiment Score hittar företag som köps av Corporate Officers.
Per definition Corporate Officers är Corporate Insiders, men till skillnad från vissa av de andra Insiders (10 % aktieägare och styrelseledamöter), arbetar ämbetsmän för företaget dagligen och de använder sina egna pengar när de handlar . (10 % aktieägare och styrelseledamöter är ofta fondförvaltare som förvaltar andras pengar.) Som sådan är insideraffärer som görs av tjänstemän mycket mer betydelsefulla och bör behandlas på lämpligt sätt.
Liksom Insider Sentiment Score är Officer Sentiment Score resultatet av en sofistikerad, kvantitativ multifaktormodell som identifierar företag med de högsta nivåerna av officersackumulering.
Uppdateringsfrekvens: Dagligen
Se insiderns bästa val, vilket ger en lista över företag med högsta insider sentiment.
Viktiga insidernyckeltal
Denna kort visar hur företaget rankas längs olika insidernyckeltal. Procenttilrankningen visar hur detta företag jämförs med andra företag på USA-marknaden. Högre rankingar indikerar bättre situationer.
Till exempel anses det allmänt att insiderköp är en positiv indikator, så företag med mer insiderköp skulle rankas högre än företag med mindre insiderköp (eller til och med insiderförsäljning).
Nettoantalet insiders som köper (rankning)
N/A
Nettoantalet insiders som köper är den totala mängden insiders som säljer minus det totala antalet insiders som säljer under de senaste 90 dagarna. Percentilrankningen visas här (intervall från 0 till 100%).
Procent av flytande köpta av insiders (ranking)
N/A
Procentandelen av aktier köpta av insiders är det totala antalet aktier som köpts av insiders minus det totala antalet aktier som sålts av insiders under de senaste 90 dagarna, dividerat med det totala antalet aktier och multiplicerat med 100.
Insiderhandelsdiagram
Aravive, Inc. insideraffärer visas i följande diagram. Insiders är tjänstemän, styrelseledamöter eller betydande investerare i ett företag. I allmänhet är det i allmänhet olagligt för insiders att göra affärer i sina företag baserat på väsentlig, icke-offentlig information. Detta betyder inte att det är olagligt för dem att göra några affärer i sina egna företag. De måste dock rapportera alla affärer till SEC via ett formulär 4.
Insiderlista och lönsamhetsstatistik
Den här tabellen visar listan över kända insiders och genereras automatiskt från anmälningar som avslöjas till SEC. Förutom namnen, den senaste titeln och direktören, tjänstemannen eller ägarbeteckningen på 10 %, tillhandahåller vi de senaste avslöjade innehaven. Dessutom, när det är möjligt tillhandahåller vi insiderns historiska handelsresultat. Det historiska handelsresultatet är ett vägt genomsnitt av resultatet för faktiska köptransaktioner på den öppna marknaden som insidern gjort. För mer information om hur detta beräknas, titta på detta YouTube-webinarium.
See our leaderboard of most profitable insider traders.
| Insider | Genomsnitt vinst (%) | Aktier Ägda |
Delad Justerad |
|---|
Report errors via our new Insider Auditing Tool
Track Records av insiderköp - Kortsiktig vinstanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i ARAV / Aravive, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste köpen på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Track Records av insiderförsäljning - Kortsiktig förlustanalys
I denna sektion analyserar vi lönsamheten för varje oplanerat, öppet-marknads insiderköp gjorda i ARAV / Aravive, Inc.. Denna analys hjälper till att förstå om insidern konsekvent genererar onormala avkastningar och är värd att följa. Denna analys är för ett år efter varje handel, och resultaten är teoretiska .
Tabellen nedan visar de senaste försäljningarna på öppna marknaden som inte var en del av en automatisk handelsplan.
Justeringar av aktierär de justerade aktierna efter justerat pris. Justeringar av aktierär de justerade aktierna efter uppdelning.
Transaktionshistorik
Klicka på länkikonen för att se hela transaktionshistoriken. Transaktioner som rapporteras som en del av en automatisk handelsplan 10b5-1 kommer att ha ett X i kolumnen markerad 10b-5.
| Fil datum |
Handel datum |
Schema | Insider | Ticker | Värdepappertitel | Kod | Direkta | Utövningspris | Enhet pris |
Enheter ändrad |
Värde ändrad (1K) |
Kvarvarande Optioner |
Kvarvarande Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-10-27 | 2022-10-24 | 4/A | Ho Peter Tai-Ching | ARAV | Common stock | I | 0,9199 | 54 353 | 50 | 55 353 | ||||
| 2022-10-27 | 2022-10-24 | 4/A | Zhang Eric | ARAV | Common stock | I | 0,9199 | 543 537 | 500 | 1 403 303 | ||||
| 2022-10-26 | 2022-10-24 | 4 | Giaccia Amato | ARAV | Common stock | D | 0,9199 | 271 768 | 250 | 1 213 648 | ||||
| 2022-10-26 | 2022-10-24 | 4 | Zhang Eric | ARAV | Common stock | D | 0,9199 | 543 537 | 500 | 1 403 303 | ||||
| 2022-10-26 | 2022-10-24 | 4 | HOWARD RUDY | ARAV | Common stock | D | 0,9199 | 10 870 | 10 | 10 870 | ||||
| 2022-10-26 | 2022-10-24 | 4 | ESHELMAN FREDRIC N | ARAV | Common Stock | I | 0,9199 | 16 306 120 | 15 000 | 25 517 889 | ||||
| 2022-10-26 | 2022-10-24 | 4 | Ho Peter Tai-Ching | ARAV | Common stock | D | 0,9199 | 54 353 | 50 | 55 353 | ||||
| 2022-10-26 | 2022-10-24 | 4 | McIntyre Gail Frances | ARAV | Common stock | D | 0,9199 | 54 353 | 50 | 65 490 | ||||
| 2022-04-04 | 2022-04-01 | 4 | ESHELMAN FREDRIC N | ARAV | Pre-Funded Warrant (right to buy) | I | 0,00 | 4 545 455 | 0 | |||||
| 2022-04-04 | 2022-04-01 | 4 | ESHELMAN FREDRIC N | ARAV | Common Stock | I | 0,0001 | 4 545 455 | 0 | 9 211 769 | ||||
| 2022-03-31 | 2022-03-29 | 4 | ESHELMAN FREDRIC N | ARAV | Warrant (right to buy) | I | 2,20 | 2,2000 | 860 216 | 1 892 | 860 216 | |||
| 2022-03-31 | 2022-03-29 | 4 | ESHELMAN FREDRIC N See Footnote 1 | ARAV | Common Stock | I | 2,3250 | 860 216 | 2 000 | 4 666 314 | ||||
| 2022-03-22 | 2022-03-21 | 4 | Dove Leonard Scott | ARAV | Stock Option (Right to buy) | D | 1,89 | 200 000 | 200 000 | |||||
| 2022-01-25 | 2022-01-24 | 4 | Rangwala Reshma | ARAV | Stock Option (Right to buy) | D | 2,18 | 175 000 | 175 000 | |||||
| 2022-01-25 | 2022-01-24 | 4 | Shah Vinay | ARAV | Stock Option (Right to buy) | D | 2,18 | 175 000 | 175 000 | |||||
| 2022-01-25 | 2022-01-24 | 4 | McIntyre Gail Frances | ARAV | Stock Option (Right to buy) | D | 2,18 | 425 000 | 425 000 | |||||
| 2022-01-05 | 2022-01-03 | 4 | ESHELMAN FREDRIC N | ARAV | Pre-Funded Warrant (right to buy) | I | 0,00 | 2,2000 | 4 545 455 | 10 000 | 4 545 455 | |||
| 2021-12-23 | 2021-12-03 | 4 | Giaccia Amato | ARAV | Common Stock | D | −48 366 | 941 880 | ||||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Stock Option | D | 0,24 | −500 | 8 620 | |||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Stock Option | D | 0,24 | −38 761 | 0 | |||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Stock Option | D | 0,06 | −12 350 | 0 | |||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 3,2200 | −39 | −0 | 990 246 | ||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 3,2200 | −2 954 | −10 | 990 285 | ||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 3,2200 | −252 | −1 | 993 239 | ||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 0,2400 | 500 | 0 | 993 491 | ||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 0,2400 | 38 761 | 9 | 992 991 | ||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 0,0600 | 12 350 | 1 | 954 230 | ||||
| 2021-09-13 | 2021-09-10 | 4 | ESHELMAN FREDRIC N | ARAV | Stock Option | D | 3,97 | 22 812 | 22 812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Giaccia Amato | ARAV | Stock Option | D | 3,97 | 22 812 | 22 812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Ho Peter Tai-Ching | ARAV | Stock Option | D | 3,97 | 22 812 | 22 812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | ROGERS MICHAEL W | ARAV | Stock Option | D | 3,97 | 22 812 | 22 812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Hohneker John | ARAV | Stock Option | D | 3,97 | 22 812 | 22 812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Zhang Eric | ARAV | Stock Option | D | 3,97 | 22 812 | 22 812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Kirk Sigurd | ARAV | Stock Option | D | 3,97 | 22 812 | 22 812 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Kirk Sigurd | ARAV | Stock Options | D | 5,80 | 5 245 | 5 245 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Kirk Sigurd | ARAV | Stock Options | D | 5,80 | 15 435 | 15 435 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Ho Peter Tai-Ching | ARAV | Stock Options | D | 5,80 | 5 245 | 5 245 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Ho Peter Tai-Ching | ARAV | Stock Options | D | 5,80 | 15 435 | 15 435 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Hohneker John | ARAV | Stock Options | D | 5,80 | 5 245 | 5 245 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Hohneker John | ARAV | Stock Options | D | 5,80 | 15 435 | 15 435 | |||||
| 2021-06-29 | 2021-06-29 | 4 | McIntyre Gail Frances | ARAV | Common Stock | D | 5,3450 | 1 000 | 5 | 11 137 | ||||
| 2021-06-29 | 2021-06-29 | 4 | Shah Vinay | ARAV | Common Stock | D | 5,3100 | 1 000 | 5 | 190 842 | ||||
| 2021-05-21 | 3 | Ho Peter Tai-Ching Hui Ping Ho Trust, 2016 | ARAV | Common Stock | I | 1 000 | ||||||||
| 2021-03-22 | 2021-03-19 | 4 | Giaccia Amato | ARAV | Stock Option (Right to buy) | D | 0,06 | −4 028 | 0 | |||||
| 2021-03-22 | 2021-03-19 | 4 | Giaccia Amato | ARAV | Stock Option (Right to buy) | D | 0,06 | −8 055 | 0 | |||||
| 2021-03-22 | 2021-03-19 | 4 | Giaccia Amato | ARAV | Common Stock | D | −12 083 | 941 880 | ||||||
| 2021-03-22 | 2021-03-19 | 4 | Giaccia Amato | ARAV | Common Stock | D | 0,0600 | 4 028 | 0 | 953 963 | ||||
| 2021-03-22 | 2021-03-19 | 4 | Giaccia Amato | ARAV | Common Stock | D | 0,0600 | 8 055 | 0 | 949 935 | ||||
| 2021-02-17 | 2021-02-12 | 4 | ESHELMAN FREDRIC N | ARAV | Common stock | I | 7,2900 | 2 875 000 | 20 959 | 3 806 098 | ||||
| 2021-01-26 | 2021-01-25 | 4 | Rangwala Reshma | ARAV | Stock Options | D | 5,95 | 10 000 | 10 000 | |||||
| 2021-01-26 | 2021-01-25 | 4 | McIntyre Gail Frances | ARAV | Stock Options | D | 5,95 | 165 000 | 165 000 | |||||
| 2021-01-26 | 2021-01-25 | 4 | Shah Vinay | ARAV | Stock Options | D | 5,95 | 60 000 | 60 000 | |||||
| 2020-12-07 | 2020-12-04 | 4 | Shah Vinay | ARAV | Common Stock | D | 5,7600 | 8 000 | 46 | 189 842 | ||||
| 2020-12-07 | 2020-12-04 | 4 | McIntyre Gail Frances | ARAV | Common Stock | D | 5,7700 | 8 000 | 46 | 10 137 | ||||
| 2020-09-29 | 2020-09-28 | 4 | Rangwala Reshma | ARAV | Stock Option | D | 4,95 | 75 000 | 75 000 | |||||
| 2020-09-17 | 2020-09-15 | 4 | ROGERS MICHAEL W | ARAV | Stock Option | D | 5,99 | 14 987 | 14 987 | |||||
| 2020-09-17 | 2020-09-15 | 4 | ROGERS MICHAEL W | ARAV | Stock Option | D | 5,99 | 15 024 | 15 024 | |||||
| 2020-09-15 | 2020-09-14 | 4 | ESHELMAN FREDRIC N | ARAV | Stock Option | D | 5,63 | 16 029 | 16 029 | |||||
| 2020-09-15 | 2020-09-14 | 4 | Tabibiazar Raymond | ARAV | Stock Option | D | 5,63 | 16 029 | 16 029 | |||||
| 2020-09-15 | 2020-09-14 | 4 | Zhang Eric | ARAV | Stock Option | D | 5,63 | 16 029 | 16 029 | |||||
| 2020-09-15 | 2020-09-14 | 4 | Giaccia Amato | ARAV | Stock Option | D | 5,63 | 16 029 | 16 029 | |||||
| 2020-06-03 | 2020-06-01 | 4 | ESHELMAN FREDRIC N | ARAV | Stock Option | D | 12,72 | 3 226 | 3 226 | |||||
| 2020-06-03 | 2020-06-01 | 4 | ESHELMAN FREDRIC N | ARAV | Stock Option | D | 12,72 | 7 500 | 7 500 | |||||
| 2020-04-10 | 3 | Eshelman Ventures, LLC | ARAV | Common Stock | I | 1 862 196 | ||||||||
| 2020-04-10 | 3 | Eshelman Ventures, LLC | ARAV | Common Stock | I | 1 862 196 | ||||||||
| 2020-04-10 | 3 | Eshelman Ventures, LLC | ARAV | Common Stock | I | 1 862 196 | ||||||||
| 2020-04-10 | 3 | Eshelman Ventures, LLC | ARAV | Common Stock | I | 1 862 196 | ||||||||
| 2020-04-09 | 2020-04-08 | 4 | McIntyre Gail Frances | ARAV | Stock Option | D | 6,16 | 80 000 | 80 000 | |||||
| 2020-04-09 | 2020-04-08 | 4 | Hemrajani Rekha | ARAV | Common Stock | D | −42 750 | 14 250 | ||||||
| 2020-04-09 | 2020-04-08 | 4 | Shepard Jay | ARAV | Common Stock | D | −9 291 | 61 201 | ||||||
| 2020-01-24 | 2020-01-22 | 4 | McIntyre Gail Frances | ARAV | Stock Option | D | 10,84 | 48 583 | 48 583 | |||||
| 2020-01-24 | 2020-01-22 | 4 | Shah Vinay | ARAV | Stock Option | D | 10,84 | 34 826 | 34 826 | |||||
| 2020-01-09 | 2020-01-09 | 4 | Shepard Jay | ARAV | Stock Option | D | 13,77 | 5 075 | 5 075 | |||||
| 2020-01-09 | 2020-01-09 | 4 | Hemrajani Rekha | ARAV | Stock Options | D | 13,77 | 143 000 | 143 000 | |||||
| 2020-01-09 | 2020-01-09 | 4 | Hemrajani Rekha | ARAV | Common Stock | D | 57 000 | 57 000 | ||||||
| 2019-12-26 | 2019-12-20 | 4 | Shepard Jay | ARAV | Common Stock | D | 11,6700 | −2 262 | −26 | 70 492 | ||||
| 2019-12-02 | 2019-12-02 | 4 | AKKARAJU SRINIVAS | ARAV | Common Stock | I | 7,5000 | 133 333 | 1 000 | 576 066 | ||||
| 2019-10-08 | 2019-10-07 | 4 | Shepard Jay | ARAV | Common Stock | D | 6,8170 | −4 004 | −27 | 72 754 | ||||
| 2019-09-13 | 2019-09-12 | 4 | Malik Shahzad | ARAV | Stock Option | D | 5,77 | 7 500 | 7 500 | |||||
| 2019-09-13 | 2019-09-12 | 4 | AKKARAJU SRINIVAS | ARAV | Stock Option | D | 5,77 | 7 500 | 7 500 | |||||
| 2019-09-13 | 2019-09-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option | D | 5,77 | 7 500 | 7 500 | |||||
| 2019-09-13 | 2019-09-12 | 4 | Giaccia Amato | ARAV | Stock Option | D | 5,77 | 7 500 | 7 500 | |||||
| 2019-09-13 | 2019-09-12 | 4 | HOFFMAN ROBERT | ARAV | Stock Option | D | 5,77 | 7 500 | 7 500 | |||||
| 2019-09-13 | 2019-09-12 | 4 | Zhang Eric | ARAV | Stock Option | D | 5,77 | 7 500 | 7 500 | |||||
| 2019-05-13 | 2019-05-10 | 4 | Shepard Jay | ARAV | Common Stock | D | 6,1100 | −1 192 | −7 | 76 758 | ||||
| 2019-03-04 | 2019-02-28 | 4 | McIntyre Gail Frances | ARAV | Stock Option | D | 5,83 | 53 000 | 53 000 | |||||
| 2019-03-04 | 2019-02-28 | 4 | Shepard Jay | ARAV | Stock Option | D | 5,83 | 116 000 | 116 000 | |||||
| 2019-03-04 | 2019-02-28 | 4 | Haas Kevin | ARAV | Stock Option | D | 5,83 | 18 000 | 18 000 | |||||
| 2019-03-04 | 2019-02-28 | 4 | Shah Vinay | ARAV | Stock Option | D | 5,83 | 38 000 | 38 000 | |||||
| 2019-02-05 | 2019-02-01 | 4 | Haas Kevin | ARAV | Common Stock | D | 4,1400 | −63 | −0 | 10 933 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Haas Kevin | ARAV | Common Stock | D | 4,1400 | −141 | −1 | 10 996 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Shepard Jay | ARAV | Common Stock | D | 4,1400 | −990 | −4 | 81 950 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Shepard Jay | ARAV | Common Stock | D | 4,1400 | −969 | −4 | 82 940 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Shepard Jay | ARAV | Common Stock | D | 4,1400 | −204 | −1 | 83 909 | ||||
| 2019-01-07 | 2019-01-03 | 4/A | Malik Shahzad | ARAV | Stock Option | D | 3,61 | 4 688 | 4 688 | |||||
| 2019-01-07 | 2019-01-03 | 4/A | HOFFMAN ROBERT | ARAV | Stock Option | D | 3,61 | 4 688 | 4 688 | |||||
| 2019-01-07 | 2019-01-03 | 4/A | HOFFMAN ROBERT | ARAV | Stock Option | D | 3,61 | 7 500 | 7 500 | |||||
| 2019-01-07 | 2019-01-03 | 4/A | Giaccia Amato | ARAV | Stock Option | D | 3,61 | 4 688 | 4 688 | |||||
| 2019-01-07 | 2019-01-03 | 4/A | Giaccia Amato | ARAV | Stock Option | D | 3,61 | 7 500 | 7 500 | |||||
| 2019-01-07 | 2019-01-03 | 4/A | AKKARAJU SRINIVAS | ARAV | Stock Option | D | 3,61 | 4 688 | 4 688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Malik Shahzad | ARAV | Stock Option | D | 3,69 | 4 688 | 4 688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | AKKARAJU SRINIVAS | ARAV | Stock Option | D | 3,69 | 4 688 | 4 688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Giaccia Amato | ARAV | Stock Option | D | 3,69 | 4 688 | 4 688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Giaccia Amato | ARAV | Stock Option | D | 3,69 | 7 500 | 7 500 | |||||
| 2019-01-07 | 2019-01-03 | 4 | HOFFMAN ROBERT | ARAV | Stock Option | D | 3,69 | 4 688 | 4 688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | HOFFMAN ROBERT | ARAV | Stock Option | D | 3,69 | 7 500 | 7 500 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Tabibiazar Raymond | ARAV | Stock Option | D | 3,61 | 4 688 | 4 688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Tabibiazar Raymond | ARAV | Stock Option | D | 3,61 | 7 500 | 7 500 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Zhang Eric | ARAV | Stock Option | D | 3,61 | 4 688 | 4 688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Zhang Eric | ARAV | Stock Option | D | 3,61 | 7 500 | 7 500 | |||||
| 2018-12-26 | 2018-12-21 | 4 | Haas Kevin | ARAV | Common Stock | D | 3,2300 | −25 | −0 | 11 137 | ||||
| 2018-12-26 | 2018-12-21 | 4 | Haas Kevin | ARAV | Common Stock | D | 3,2170 | −686 | −2 | 11 162 | ||||
| 2018-12-26 | 2018-12-21 | 4 | Shepard Jay | ARAV | Common Stock | D | 3,2240 | −3 484 | −11 | 84 113 | ||||
| 2018-12-19 | 2018-12-17 | 4 | Haas Kevin | ARAV | Common Stock | D | 3,9620 | −1 164 | −5 | 11 848 | ||||
| 2018-12-19 | 2018-12-17 | 4 | Shepard Jay | ARAV | Common Stock | D | 3,9620 | −11 247 | −45 | 87 597 | ||||
| 2018-10-16 | 2018-10-12 | 4 | Zhang Eric | ARAV | Common Stock | I | 859 766 | 859 766 | ||||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,90 | 28 501 | 28 501 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,90 | 28 501 | 28 501 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,66 | 57 002 | 57 002 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,24 | 15 200 | 15 200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,24 | 15 200 | 15 200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,24 | 15 200 | 15 200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,24 | 15 200 | 15 200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,24 | 254 177 | 254 177 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,24 | 65 365 | 65 365 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,24 | 15 200 | 15 200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,24 | 15 200 | 15 200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,24 | 51 682 | 51 682 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,06 | 12 084 | 12 084 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0,06 | 46 322 | 46 322 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Common Stock | D | 1 000 751 | 1 000 751 | ||||||
| 2018-10-16 | 2018-10-12 | 4 | Shah Vinay | ARAV | Stock Option (Right to Buy) | D | 0,90 | 19 000 | 19 000 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Shah Vinay | ARAV | Stock Option (Right to Buy) | D | 0,90 | 19 000 | 19 000 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Shah Vinay | ARAV | Stock Option (Right to Buy) | D | 0,66 | 38 001 | 38 001 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Shah Vinay | ARAV | Stock Option (Right to Buy) | D | 0,24 | 19 380 | 19 380 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Shah Vinay | ARAV | Common Stock | D | 178 606 | 178 606 | ||||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,90 | 19 000 | 19 000 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (RIght to Buy) | D | 0,90 | 19 000 | 19 000 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,66 | 38 001 | 38 001 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,24 | 9 120 | 9 120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,24 | 9 120 | 9 120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,24 | 9 120 | 9 120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,24 | 9 120 | 9 120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,24 | 26 813 | 26 813 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,24 | 9 120 | 9 120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,24 | 9 120 | 9 120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,24 | 38 761 | 38 761 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,06 | 12 350 | 12 350 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,06 | 4 028 | 4 028 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0,06 | 8 055 | 8 055 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Common Stock | D | 941 880 | 941 880 | ||||||
| 2018-10-16 | 3 | Zhang Eric | ARAV | Common Stock | D | 0 | ||||||||
| 2018-10-16 | 3 | Shah Vinay | ARAV | Common Stock | D | 0 | ||||||||
| 2018-10-16 | 3 | Tabibiazar Raymond | ARAV | Common Stock | D | 0 | ||||||||
| 2018-10-16 | 3 | Giaccia Amato | ARAV | Common Stock | D | 0 | ||||||||
| 2018-10-16 | 2018-10-12 | 4 | AKKARAJU SRINIVAS | ARAV | Common Stock | D | 27 456 | 31 815 | ||||||
| 2018-10-16 | 3 | HOFFMAN ROBERT | ARAV | Common Stock | D | 0 | ||||||||
| 2018-06-19 | 2018-06-15 | 4 | Haas Kevin | VSAR | Common Stock | D | 2,3000 | −143 | −0 | 78 075 | ||||
| 2018-06-19 | 2018-06-15 | 4 | Westberg Paul | VSAR | Common Stock | D | 2,3000 | −612 | −1 | 225 124 | ||||
| 2018-06-15 | 2018-06-13 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 2,1300 | 53 018 | 113 | 2 682 554 | ||||
| 2018-06-08 | 2018-06-08 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 2,0000 | 231 580 | 463 | 2 629 536 | ||||
| 2018-06-08 | 2018-06-07 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 1,8500 | 163 224 | 302 | 2 397 956 | ||||
| 2018-06-08 | 2018-06-06 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 1,7400 | 660 681 | 1 150 | 2 234 732 | ||||
| 2018-05-23 | 2018-05-22 | 4 | Shepard Jay | VSAR | Common Stock | D | 1,5000 | −9 232 | −14 | 593 066 | ||||
| 2018-04-25 | 2018-04-24 | 4 | Stout Jay S | VSAR | Common Stock | D | 1,5500 | −4 854 | −8 | 185 646 | ||||
| 2018-03-26 | 2018-03-23 | 4 | Woody Tracy M | VSAR | Common Stock | D | 1,7500 | −4 345 | −8 | 215 755 | ||||
| 2018-02-12 | 2018-02-08 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,8000 | −5 355 | −10 | 225 736 | ||||
| 2018-02-12 | 2018-02-08 | 4 | Ward Shane | VSAR | Common Stock | D | 1,8000 | −4 118 | −7 | 201 556 | ||||
| 2018-02-12 | 2018-02-08 | 4 | Shepard Jay | VSAR | Common Stock | D | 1,8000 | −14 446 | −26 | 602 298 | ||||
| 2018-02-12 | 2018-02-08 | 4 | Haas Kevin | VSAR | Common Stock | D | 1,8000 | −1 599 | −3 | 78 218 | ||||
| 2017-12-22 | 2017-12-20 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 11 200 | 44 380 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Gut Robert | VSAR | Common Stock | D | 91 300 | 227 300 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Haas Kevin | VSAR | Common Stock | D | 44 700 | 79 817 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | JENNINGS EDMON R | VSAR | Common Stock | D | 11 200 | 22 380 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Malik Shahzad | VSAR | Common Stock | D | 11 200 | 23 880 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Shepard Jay | VSAR | Common Stock | D | 223 000 | 616 744 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Stout Jay S | VSAR | Common Stock | D | 74 500 | 190 500 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | SUN ANTHONY Y | VSAR | Common Stock | D | 11 200 | 23 880 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Varian John | VSAR | Common Stock | D | 11 200 | 22 280 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Ward Shane | VSAR | Common Stock | D | 93 100 | 205 674 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Westberg Paul | VSAR | Common Stock | D | 90 900 | 231 091 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Woody Tracy M | VSAR | Common Stock | D | 93 100 | 220 100 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 11 200 | 26 155 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | DOBMEIER ERIC | VSAR | Common Stock | D | 11 200 | 18 160 | ||||||
| 2017-12-05 | 2017-12-05 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 2,0000 | 42 895 | 86 | 1 547 896 | ||||
| 2017-12-05 | 2017-12-04 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 2,2100 | 513 872 | 1 136 | 1 505 001 | ||||
| 2017-12-05 | 2017-12-01 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 2,1300 | 419 700 | 894 | 991 129 | ||||
| 2017-12-04 | 3 | Haas Kevin | VSAR | Common Stock | D | 70 234 | ||||||||
| 2017-12-04 | 3 | Haas Kevin | VSAR | Common Stock | D | 70 234 | ||||||||
| 2017-11-29 | 2017-11-28 | 4 | Ward Shane | VSAR | Common Stock | D | 20 000 | 112 574 | ||||||
| 2017-11-29 | 2017-11-28 | 4 | Westberg Paul | VSAR | Common Stock | D | 15 000 | 140 191 | ||||||
| 2017-10-23 | 2017-10-19 | 4 | Westberg Paul | VSAR | Common Stock | D | 2,5500 | −1 326 | −3 | 125 191 | ||||
| 2017-10-23 | 2017-10-19 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 2,5500 | −1 326 | −3 | 201 269 | ||||
| 2017-10-23 | 2017-10-19 | 4 | Hislop Colin | VSAR | Common Stock | D | 2,5500 | −667 | −2 | 23 833 | ||||
| 2017-10-23 | 2017-10-19 | 4 | Ward Shane | VSAR | Common Stock | D | 2,5500 | −776 | −2 | 92 574 | ||||
| 2017-10-10 | 2017-10-06 | 4 | Shepard Jay | VSAR | Common Stock | D | 189 000 | 393 744 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Stout Jay S | VSAR | Common Stock | D | 70 000 | 116 000 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Ward Shane | VSAR | Common Stock | D | 57 000 | 93 350 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Westberg Paul | VSAR | Common Stock | D | 59 000 | 126 517 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Woody Tracy M | VSAR | Common Stock | D | 82 000 | 127 000 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 97 000 | 202 595 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Gut Robert | VSAR | Common Stock | D | 88 000 | 136 000 | ||||||
| 2017-09-25 | 2017-09-22 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3,3500 | −350 000 | −1 172 | 2 099 563 | ||||
| 2017-09-25 | 2017-09-22 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3,2665 | −500 000 | −1 633 | 2 449 563 | ||||
| 2017-09-25 | 2017-09-22 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3,1700 | −250 000 | −792 | 2 949 563 | ||||
| 2017-09-25 | 2017-09-22 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3,0290 | −250 000 | −757 | 3 199 563 | ||||
| 2017-09-25 | 2017-09-22 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3,0875 | −300 000 | −926 | 3 449 563 | ||||
| 2017-09-25 | 2017-09-21 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3,5599 | −353 421 | −1 258 | 3 749 563 | ||||
| 2017-09-25 | 2017-09-21 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3,7420 | −126 579 | −474 | 4 102 984 | ||||
| 2017-09-06 | 3 | Gut Robert | VSAR | No securities held. | D | 0 | ||||||||
| 2017-09-06 | 2017-09-05 | 4 | Gut Robert | VSAR | Stock Option (Right to Buy) | D | 19,80 | 107 000 | 107 000 | |||||
| 2017-09-06 | 2017-09-05 | 4 | Gut Robert | VSAR | Common Stock | D | 48 000 | 48 000 | ||||||
| 2017-06-14 | 2017-06-13 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 16,0500 | −1 421 | −23 | 105 595 | ||||
| 2017-06-14 | 2017-06-13 | 4 | Westberg Paul | VSAR | Common Stock | D | 16,0500 | −711 | −11 | 67 517 | ||||
| 2017-06-06 | 3 | DOBMEIER ERIC | VSAR | Common Stock | D | 0 | ||||||||
| 2017-06-06 | 2017-05-25 | 4 | JENNINGS EDMON R | VSAR | Stock Option (Right to Buy) | D | 15,82 | 6 850 | 6 850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | JENNINGS EDMON R | VSAR | Common Stock | D | 3 480 | 11 180 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | GREER R SCOTT | VSAR | Stock Option (Right to Buy) | D | 15,82 | 6 850 | 6 850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 3 480 | 33 180 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | AKKARAJU SRINIVAS | VSAR | Stock Option (Right to Buy) | D | 15,82 | 6 850 | 6 850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 3 480 | 14 955 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | DOBMEIER ERIC | VSAR | Stock Option (Right to Buy) | D | 15,82 | 6 850 | 6 850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | DOBMEIER ERIC | VSAR | Stock Option (Right to Buy) | D | 15,82 | 6 850 | 6 850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | DOBMEIER ERIC | VSAR | Common Stock | D | 3 480 | 6 960 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | DOBMEIER ERIC | VSAR | Common Stock | D | 3 480 | 6 960 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | Varian John | VSAR | Stock Option (Right to Buy) | D | 15,82 | 6 850 | 6 850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | Varian John | VSAR | Common Stock | D | 3 480 | 11 080 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | SUN ANTHONY Y | VSAR | Stock Option (Right to Buy) | D | 15,82 | 6 850 | 6 850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | SUN ANTHONY Y | VSAR | Common Stock | D | 3 480 | 12 680 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | Malik Shahzad | VSAR | Stock Option (Right to Buy) | D | 15,82 | 6 850 | 6 850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | Malik Shahzad | VSAR | Common Stock | D | 3 480 | 12 680 | ||||||
| 2017-05-17 | 2017-05-16 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 17,4000 | −1 263 | −22 | 107 016 | ||||
| 2017-05-15 | 2017-05-11 | 4 | Shepard Jay | VSAR | Common Stock | D | 17,5000 | −9 114 | −159 | 204 744 | ||||
| 2017-04-20 | 2017-04-19 | 4 | Westberg Paul | VSAR | Common Stock | D | 19,8500 | −1 316 | −26 | 68 228 | ||||
| 2017-04-05 | 3 | Stout Jay S | VSAR | Common Stock | D | 2 000 | ||||||||
| 2017-04-05 | 3 | Stout Jay S | VSAR | Common Stock | D | 2 000 | ||||||||
| 2017-04-05 | 2017-04-03 | 4 | Stout Jay S | VSAR | Stock Option (Right to Buy) | D | 21,30 | 75 000 | 75 000 | |||||
| 2017-04-05 | 2017-04-03 | 4 | Stout Jay S | VSAR | Common Stock | D | 45 000 | 46 000 | ||||||
| 2017-04-05 | 2017-04-04 | 4 | Hislop Colin | VSAR | Stock Option (Right to Buy) | D | 8,17 | −35 000 | 188 100 | |||||
| 2017-04-05 | 2017-04-04 | 4 | Hislop Colin | VSAR | Common Stock | D | 21,2000 | −35 000 | −742 | 24 500 | ||||
| 2017-04-05 | 2017-04-04 | 4 | Hislop Colin | VSAR | Common Stock | D | 8,1700 | 35 000 | 286 | 59 500 | ||||
| 2017-03-31 | 3 | Woody Tracy M | VSAR | Common Stock | D | 0 | ||||||||
| 2017-03-31 | 2017-03-22 | 4 | Woody Tracy M | VSAR | Stock Option (Right to Buy) | D | 20,15 | 100 000 | 100 000 | |||||
| 2017-03-31 | 2017-03-22 | 4 | Woody Tracy M | VSAR | Common Stock | D | 45 000 | 45 000 | ||||||
| 2017-03-28 | 2017-03-24 | 4 | AKKARAJU SRINIVAS By Partnership | VSAR | Common Stock | I | 12,2500 | 571 429 | 7 000 | 571 429 | ||||
| 2017-03-17 | 2017-03-17 | 4 | Malik Shahzad | VSAR | Common Stock | I | 18,0100 | −386 367 | −6 958 | 1 621 558 | ||||
| 2017-03-17 | 2017-03-16 | 4 | Malik Shahzad | VSAR | Common Stock | I | 18,5000 | −97 303 | −1 800 | 2 007 925 | ||||
| 2017-03-15 | 2017-03-15 | 4 | Malik Shahzad | VSAR | Common Stock | I | 19,0800 | −103 122 | −1 968 | 2 105 228 | ||||
| 2017-03-15 | 2017-03-14 | 4 | Malik Shahzad | VSAR | Common Stock | I | 19,0000 | −46 778 | −889 | 2 208 350 | ||||
| 2017-03-15 | 2017-03-14 | 4 | Malik Shahzad | VSAR | Common Stock | I | 19,0300 | −100 | −2 | 2 255 128 | ||||
| 2017-03-15 | 2017-03-13 | 4 | Malik Shahzad | VSAR | Common Stock | I | 19,4200 | −16 330 | −317 | 2 255 228 | ||||
| 2017-03-15 | 2017-03-15 | 4 | Ward Shane | VSAR | Common Stock | D | 19,0200 | −776 | −15 | 36 350 | ||||
| 2017-03-15 | 2017-03-14 | 4 | Ward Shane | VSAR | Common Stock | D | 19,0000 | −1 265 | −24 | 37 126 | ||||
| 2017-03-14 | 2017-02-13 | 4/A | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 15,5146 | 59 133 | 917 | 4 229 563 | ||||
| 2017-03-14 | 2017-02-10 | 4/A | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14,9437 | 34 883 | 521 | 4 170 430 | ||||
| 2017-02-28 | 2017-02-24 | 4 | Brumm Joshua T | VSAR | Stock Option (Right to Buy) | D | 2,53 | −30 000 | 122 108 | |||||
| 2017-02-28 | 2017-02-24 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 22,0500 | −5 653 | −125 | 105 779 | ||||
| 2017-02-28 | 2017-02-24 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 21,4600 | −6 008 | −129 | 111 432 | ||||
| 2017-02-28 | 2017-02-24 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 20,4200 | −18 339 | −374 | 117 440 | ||||
| 2017-02-28 | 2017-02-24 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 2,5300 | 30 000 | 76 | 135 779 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2,53 | −5 166 | 65 828 | |||||
| 2017-02-28 | 2017-02-27 | 4 | Shepard Jay | VSAR | Common Stock | D | 24,0000 | −5 166 | −124 | 213 858 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Shepard Jay | VSAR | Common Stock | D | 2,5300 | 5 166 | 13 | 219 024 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 2,53 | −4 991 | 7 491 | |||||
| 2017-02-28 | 2017-02-27 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,61 | −7 509 | 2 975 | |||||
| 2017-02-28 | 2017-02-27 | 4 | Westberg Paul | VSAR | Common Stock | D | 22,5000 | −12 500 | −281 | 69 544 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Westberg Paul | VSAR | Common Stock | D | 2,5300 | 4 991 | 13 | 82 044 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,6100 | 7 509 | 12 | 77 053 | ||||
| 2017-02-23 | 2017-02-23 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,61 | −6 590 | 10 484 | |||||
| 2017-02-23 | 2017-02-23 | 4 | Westberg Paul | VSAR | Common Stock | D | 20,0000 | −6 590 | −132 | 69 544 | ||||
| 2017-02-23 | 2017-02-23 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,6100 | 6 590 | 11 | 76 134 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,61 | −3 323 | 17 074 | |||||
| 2017-02-23 | 2017-02-21 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,61 | −15 087 | 506 | |||||
| 2017-02-23 | 2017-02-21 | 4 | Westberg Paul | VSAR | Common Stock | D | 20,0000 | −5 910 | −118 | 69 544 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Westberg Paul | VSAR | Common Stock | D | 17,5000 | −12 500 | −219 | 75 454 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,6100 | 18 410 | 30 | 87 954 | ||||
| 2017-02-23 | 2017-02-23 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2,53 | −8 000 | 70 994 | |||||
| 2017-02-23 | 2017-02-23 | 4 | Shepard Jay | VSAR | Common Stock | D | 20,0000 | −8 000 | −160 | 213 858 | ||||
| 2017-02-23 | 2017-02-23 | 4 | Shepard Jay | VSAR | Common Stock | D | 2,5300 | 8 000 | 20 | 221 858 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2,53 | −8 000 | 78 994 | |||||
| 2017-02-23 | 2017-02-21 | 4 | Shepard Jay | VSAR | Common Stock | D | 18,5000 | −8 000 | −148 | 213 858 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Shepard Jay | VSAR | Common Stock | D | 2,5300 | 8 000 | 20 | 221 858 | ||||
| 2017-02-14 | 2017-02-13 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 15,5146 | 59 133 | 917 | 4 228 563 | ||||
| 2017-02-14 | 2017-02-10 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14,9437 | 34 883 | 521 | 4 169 430 | ||||
| 2017-02-10 | 2017-02-09 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14,2663 | 41 211 | 588 | 4 134 547 | ||||
| 2017-02-10 | 2017-02-08 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 13,5101 | 104 612 | 1 413 | 4 093 336 | ||||
| 2017-02-06 | 2017-02-03 | 4 | Shepard Jay | VSAR | Common Stock | D | 13,6900 | −6 719 | −92 | 213 858 | ||||
| 2017-02-02 | 2017-02-02 | 4 | Shepard Jay | VSAR | Common Stock | D | 13,5100 | −6 973 | −94 | 220 577 | ||||
| 2017-02-02 | 2017-02-02 | 4 | Shepard Jay | VSAR | Common Stock | D | 2,5300 | 4 166 | 11 | 227 550 | ||||
| 2017-02-02 | 2017-02-01 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2,53 | −4 166 | 86 994 | |||||
| 2017-02-02 | 2017-02-01 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2,53 | −6 576 | 91 160 | |||||
| 2017-02-02 | 2017-02-01 | 4 | Shepard Jay | VSAR | Common Stock | D | 13,9500 | −6 576 | −92 | 223 384 | ||||
| 2017-02-02 | 2017-02-01 | 4 | Shepard Jay | VSAR | Common Stock | D | 2,5300 | 6 576 | 17 | 229 960 | ||||
| 2017-02-02 | 2017-01-31 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2,53 | −10 662 | 97 736 | |||||
| 2017-02-02 | 2017-01-31 | 4 | Shepard Jay | VSAR | Common Stock | D | 14,1600 | −5 940 | −84 | 223 384 | ||||
| 2017-02-02 | 2017-01-31 | 4 | Shepard Jay | VSAR | Common Stock | D | 13,4000 | −4 722 | −63 | 229 324 | ||||
| 2017-02-02 | 2017-01-31 | 4 | Shepard Jay | VSAR | Common Stock | D | 2,5300 | 10 662 | 27 | 234 046 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Hislop Colin | VSAR | Stock Option (Right to Buy) | D | 14,30 | 43 700 | 43 700 | |||||
| 2017-01-31 | 2017-01-27 | 4 | Hislop Colin | VSAR | Common Stock | D | 19 500 | 24 500 | ||||||
| 2017-01-31 | 2017-01-30 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 13,8520 | −2 945 | −41 | 105 779 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Brumm Joshua T | VSAR | Stock Option (Right to Buy) | D | 14,30 | 65 590 | 65 590 | |||||
| 2017-01-31 | 2017-01-27 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 43 900 | 108 724 | ||||||
| 2017-01-31 | 2017-01-30 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2,53 | −10 596 | 108 398 | |||||
| 2017-01-31 | 2017-01-30 | 4 | Shepard Jay | VSAR | Common Stock | D | 13,3100 | −10 596 | −141 | 223 384 | ||||
| 2017-01-31 | 2017-01-30 | 4 | Shepard Jay | VSAR | Common Stock | D | 2,5300 | 10 596 | 27 | 233 980 | ||||
| 2017-01-31 | 2017-01-30 | 4 | Shepard Jay | VSAR | Common Stock | D | 13,8500 | −6 674 | −92 | 223 384 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 14,30 | 144 900 | 144 900 | |||||
| 2017-01-31 | 2017-01-27 | 4 | Shepard Jay | VSAR | Common Stock | D | 10 000 | 230 058 | ||||||
| 2017-01-31 | 2017-01-27 | 4 | Shepard Jay | VSAR | Common Stock | D | 64 700 | 220 058 | ||||||
| 2017-01-31 | 2017-01-30 | 4 | Westberg Paul | VSAR | Common Stock | D | 13,8520 | −1 916 | −27 | 69 544 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 14,30 | 40 130 | 40 130 | |||||
| 2017-01-31 | 2017-01-27 | 4 | Westberg Paul | VSAR | Common Stock | D | 26 860 | 71 460 | ||||||
| 2017-01-31 | 2017-01-30 | 4 | Ward Shane | VSAR | Common Stock | D | 13,8520 | −1 474 | −20 | 38 391 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Ward Shane | VSAR | Stock Option (Right to Buy) | D | 14,30 | 46 200 | 46 200 | |||||
| 2017-01-31 | 2017-01-27 | 4 | Ward Shane | VSAR | Common Stock | D | 20 600 | 39 865 | ||||||
| 2017-01-11 | 2017-01-11 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,61 | −7 931 | 15 593 | |||||
| 2017-01-11 | 2017-01-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 15,2400 | −7 931 | −121 | 44 600 | ||||
| 2017-01-11 | 2017-01-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,6100 | 7 931 | 13 | 52 531 | ||||
| 2017-01-11 | 2017-01-10 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,61 | −746 | 23 524 | |||||
| 2017-01-11 | 2017-01-10 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,38 | −10 467 | 0 | |||||
| 2017-01-11 | 2017-01-10 | 4 | Westberg Paul | VSAR | Common Stock | D | 15,6600 | −11 213 | −176 | 44 600 | ||||
| 2017-01-11 | 2017-01-10 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,6100 | 746 | 1 | 55 813 | ||||
| 2017-01-11 | 2017-01-10 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,3800 | 10 467 | 14 | 55 067 | ||||
| 2017-01-11 | 2017-01-09 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,38 | −11 044 | 10 467 | |||||
| 2017-01-11 | 2017-01-09 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −2 312 | 0 | |||||
| 2017-01-11 | 2017-01-09 | 4 | Westberg Paul | VSAR | Common Stock | D | 15,9300 | −13 356 | −213 | 44 600 | ||||
| 2017-01-11 | 2017-01-09 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,3800 | 11 044 | 15 | 57 956 | ||||
| 2017-01-11 | 2017-01-09 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 2 312 | 3 | 46 912 | ||||
| 2017-01-04 | 2016-12-30 | 4/A | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14,6580 | 71 063 | 1 042 | 3 989 724 | ||||
| 2017-01-04 | 2016-12-30 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14,6580 | 94 750 | 1 389 | 4 013 411 | ||||
| 2016-12-30 | 2016-12-29 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14,3660 | 47 375 | 681 | 3 918 661 | ||||
| 2016-12-29 | 2016-12-27 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 15,8500 | −990 | −16 | 64 824 | ||||
| 2016-12-29 | 2016-12-27 | 4 | Westberg Paul | VSAR | Common Stock | D | 15,8500 | −361 | −6 | 44 600 | ||||
| 2016-12-19 | 2016-12-16 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −5 000 | 2 312 | |||||
| 2016-12-19 | 2016-12-16 | 4 | Westberg Paul | VSAR | Common Stock | D | 15,0000 | −5 000 | −75 | 44 961 | ||||
| 2016-12-19 | 2016-12-16 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 5 000 | 6 | 49 961 | ||||
| 2016-12-08 | 2016-12-08 | 4 | JENNINGS EDMON R | VSAR | Common Stock | D | 12,9550 | −1 500 | −19 | 7 700 | ||||
| 2016-12-08 | 2016-12-07 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 13,2500 | −3 021 | −40 | 65 814 | ||||
| 2016-10-13 | 2016-10-11 | 4 | Hislop Colin | VSAR | Common Stock | D | 5 000 | 5 000 | ||||||
| 2016-10-13 | 2016-10-11 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 10 000 | 68 835 | ||||||
| 2016-10-13 | 2016-10-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 10 000 | 44 961 | ||||||
| 2016-10-13 | 2016-10-11 | 4 | Ward Shane | VSAR | Common Stock | D | 5 000 | 19 265 | ||||||
| 2016-10-05 | 3/A | EDELMAN JOSEPH See Footnotes | VSAR | Common Stock | I | 3 871 286 | ||||||||
| 2016-10-04 | 2016-10-03 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 12,2500 | 571 429 | 7 000 | 571 429 | ||||
| 2016-09-28 | 3 | EDELMAN JOSEPH See Footnotes | VSAR | Common Stock | I | 7 594 838 | ||||||||
| 2016-09-28 | 3 | EDELMAN JOSEPH See Footnotes | VSAR | Common Stock | I | 7 594 838 | ||||||||
| 2016-09-28 | 3 | EDELMAN JOSEPH See Footnotes | VSAR | Common Stock | I | 7 594 838 | ||||||||
| 2016-09-28 | 3 | EDELMAN JOSEPH See Footnotes | VSAR | Common Stock | I | 7 594 838 | ||||||||
| 2016-08-26 | 2016-08-25 | 4 | Varian John | VSAR | Common Stock | D | 12,9718 | −1 600 | −21 | 7 600 | ||||
| 2016-08-24 | 2016-08-22 | 4 | Shepard Jay | VSAR | Common Stock | D | 12,8800 | −5 442 | −70 | 155 358 | ||||
| 2016-06-20 | 2016-06-14 | 4 | AKKARAJU SRINIVAS | VSAR | Stock Option (Right to Buy) | D | 10,87 | 28 720 | 28 720 | |||||
| 2016-06-20 | 2016-06-14 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 6 900 | 11 475 | ||||||
| 2016-06-17 | 2016-06-15 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 10,6300 | −1 448 | −15 | 58 835 | ||||
| 2016-06-17 | 2016-06-15 | 4 | Westberg Paul | VSAR | Common Stock | D | 10,6300 | −725 | −8 | 34 961 | ||||
| 2016-05-20 | 2016-05-18 | 4 | Varian John | VSAR | Stock Option (Right to Buy) | D | 8,12 | 14 625 | 14 625 | |||||
| 2016-05-20 | 2016-05-18 | 4 | Varian John | VSAR | Common Stock | D | 4 625 | 9 200 | ||||||
| 2016-05-20 | 2016-05-18 | 4 | SUN ANTHONY Y | VSAR | Stock Option (Right to Buy) | D | 8,12 | 14 625 | 14 625 | |||||
| 2016-05-20 | 2016-05-18 | 4 | SUN ANTHONY Y | VSAR | Common Stock | D | 4 625 | 9 200 | ||||||
| 2016-05-20 | 2016-05-18 | 4 | JENNINGS EDMON R | VSAR | Stock Option (Right to Buy) | D | 8,12 | 14 625 | 14 625 | |||||
| 2016-05-20 | 2016-05-18 | 4 | JENNINGS EDMON R | VSAR | Common Stock | D | 4 625 | 9 200 | ||||||
| 2016-05-20 | 2016-05-18 | 4 | GREER R SCOTT | VSAR | Stock Option (Right to Buy) | D | 8,12 | 14 625 | 14 625 | |||||
| 2016-05-20 | 2016-05-18 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 4 625 | 29 700 | ||||||
| 2016-05-20 | 2016-05-18 | 4 | Malik Shahzad | VSAR | Stock Option (Right to Buy) | D | 8,12 | 14 625 | 14 625 | |||||
| 2016-05-20 | 2016-05-18 | 4 | Malik Shahzad | VSAR | Common Stock | D | 4 625 | 9 200 | ||||||
| 2016-05-20 | 2016-05-20 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 7,8700 | −1 265 | −10 | 60 283 | ||||
| 2016-05-02 | 3 | Hislop Colin | VSAR | Common Stock | D | 0 | ||||||||
| 2016-05-02 | 2016-04-04 | 4 | Hislop Colin | VSAR | Stock Option (Right to Buy) | D | 8,17 | 223 100 | 223 100 | |||||
| 2016-04-25 | 2016-04-21 | 4 | Westberg Paul | VSAR | Common Stock | D | 9,6800 | −1 430 | −14 | 35 686 | ||||
| 2016-02-01 | 2016-01-28 | 4 | Brumm Joshua T | VSAR | Stock Option (Right to Buy) | D | 10,68 | 83 800 | 83 800 | |||||
| 2016-02-01 | 2016-01-28 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 26 000 | 61 548 | ||||||
| 2016-02-01 | 2016-01-28 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 10,68 | 54 400 | 54 400 | |||||
| 2016-02-01 | 2016-01-28 | 4 | Westberg Paul | VSAR | Common Stock | D | 16 900 | 37 116 | ||||||
| 2016-02-01 | 2016-01-28 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 10,68 | 209 200 | 209 200 | |||||
| 2016-02-01 | 2016-01-28 | 4 | Shepard Jay | VSAR | Common Stock | D | 64 800 | 160 800 | ||||||
| 2016-02-01 | 2016-01-28 | 4 | Ward Shane | VSAR | Stock Option (Right to Buy) | D | 10,68 | 42 000 | 42 000 | |||||
| 2016-02-01 | 2016-01-28 | 4 | Ward Shane | VSAR | Common Stock | D | 13 000 | 14 265 | ||||||
| 2016-01-04 | 2015-12-30 | 4 | Westberg Paul | VSAR | Common Stock | D | 12,4360 | −362 | −5 | 20 216 | ||||
| 2016-01-04 | 2015-12-30 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 12,4360 | −990 | −12 | 35 548 | ||||
| 2015-11-13 | 2015-11-12 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 9,9900 | 2 500 | 25 | 36 538 | ||||
| 2015-11-13 | 2015-11-11 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 10,1700 | 9 500 | 97 | 25 075 | ||||
| 2015-11-13 | 2015-11-11 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 10,1600 | 200 | 2 | 15 575 | ||||
| 2015-11-13 | 2015-11-11 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 10,1500 | 300 | 3 | 15 375 | ||||
| 2015-08-05 | 2015-08-04 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −2 400 | 7 312 | |||||
| 2015-08-05 | 2015-08-04 | 4 | Westberg Paul | VSAR | Common Stock | D | 18,5300 | −142 | −3 | 20 578 | ||||
| 2015-08-05 | 2015-08-04 | 4 | Westberg Paul | VSAR | Common Stock | D | 18,2500 | −2 258 | −41 | 20 720 | ||||
| 2015-08-05 | 2015-08-04 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 2 400 | 3 | 22 978 | ||||
| 2015-07-07 | 2015-07-06 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −2 400 | 9 712 | |||||
| 2015-07-07 | 2015-07-06 | 4 | Westberg Paul | VSAR | Common Stock | D | 15,0000 | −2 400 | −36 | 20 578 | ||||
| 2015-07-07 | 2015-07-06 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 2 400 | 3 | 22 978 | ||||
| 2015-07-01 | 2015-06-29 | 4 | GREER R SCOTT | VSAR | Stock Option (Right to Buy) | D | 14,73 | 13 100 | 13 100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 4 575 | 15 075 | ||||||
| 2015-07-01 | 2015-06-29 | 4 | JENNINGS EDMON R | VSAR | Stock Option (Right to Buy) | D | 14,73 | 13 100 | 13 100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | JENNINGS EDMON R | VSAR | Common Stock | D | 4 575 | 4 575 | ||||||
| 2015-07-01 | 2015-06-29 | 4 | AKKARAJU SRINIVAS | VSAR | Stock Option (Right to Buy) | D | 14,73 | 13 100 | 13 100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 4 575 | 4 575 | ||||||
| 2015-07-01 | 2015-06-29 | 4 | SUN ANTHONY Y | VSAR | Stock Option (Right to Buy) | D | 14,73 | 13 100 | 13 100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | SUN ANTHONY Y | VSAR | Common Stock | D | 4 575 | 4 575 | ||||||
| 2015-07-01 | 2015-06-29 | 4 | Varian John | VSAR | Stock Option (Right to Buy) | D | 14,73 | 13 100 | 13 100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | Varian John | VSAR | Common Stock | D | 4 575 | 4 575 | ||||||
| 2015-07-01 | 2015-06-29 | 4 | Malik Shahzad | VSAR | Stock Option (Right to Buy) | D | 14,73 | 13 100 | 13 100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | Malik Shahzad | VSAR | Common Stock | D | 4 575 | 4 575 | ||||||
| 2015-06-15 | 2015-06-11 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 17,2800 | −1 375 | −24 | 34 038 | ||||
| 2015-06-15 | 2015-06-11 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 19,9000 | −1 222 | −24 | 35 413 | ||||
| 2015-06-15 | 2015-06-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 17,2800 | −687 | −12 | 20 578 | ||||
| 2015-06-15 | 2015-06-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 19,9000 | −1 222 | −24 | 21 265 | ||||
| 2015-06-04 | 2015-06-03 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −2 400 | 12 112 | |||||
| 2015-06-04 | 2015-06-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 16,7259 | −2 400 | −40 | 22 487 | ||||
| 2015-06-04 | 2015-06-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 2 400 | 3 | 24 887 | ||||
| 2015-05-13 | 2015-05-11 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 15,19 | 309 000 | 309 000 | |||||
| 2015-05-13 | 2015-05-11 | 4 | Shepard Jay | VSAR | Common Stock | D | 96 000 | 96 000 | ||||||
| 2015-05-06 | 2015-05-04 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −2 400 | 14 512 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Westberg Paul | VSAR | Common Stock | D | 17,4706 | −2 400 | −42 | 22 487 | ||||
| 2015-05-06 | 2015-05-04 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 2 400 | 3 | 24 887 | ||||
| 2015-04-16 | 2014-12-22 | 4/A | Cleland Jeffrey L | VSAR | Common Stock | D | 21,3561 | −5 870 | −125 | 133 388 | ||||
| 2015-04-16 | 2014-12-22 | 4/A | Cleland Jeffrey L | VSAR | Common Stock | D | 20,5364 | −2 110 | −43 | 139 258 | ||||
| 2015-04-16 | 2014-12-19 | 4/A | Cleland Jeffrey L | VSAR | Common Stock | D | 20,0000 | −20 | −0 | 141 368 | ||||
| 2015-04-16 | 2014-11-14 | 4/A | Cleland Jeffrey L | VSAR | Common Stock | D | −1 900 | 141 388 | ||||||
| 2015-04-16 | 2014-12-15 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 496 | 142 396 | ||||||
| 2015-04-16 | 2015-04-14 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,1300 | −8 000 | −161 | 121 548 | ||||
| 2015-04-08 | 3 | Ward Shane | VSAR | Common Stock | D | 0 | ||||||||
| 2015-04-08 | 2015-04-06 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −2 041 | 16 912 | |||||
| 2015-04-08 | 2015-04-06 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −359 | 0 | |||||
| 2015-04-08 | 2015-04-06 | 4 | Westberg Paul | VSAR | Common Stock | D | 17,4884 | −2 400 | −42 | 22 487 | ||||
| 2015-04-08 | 2015-04-06 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 2 400 | 3 | 24 887 | ||||
| 2015-04-08 | 2015-04-06 | 4 | Ward Shane | VSAR | Stock Option (Right to Buy) | D | 17,47 | 50 000 | 50 000 | |||||
| 2015-03-24 | 2015-03-23 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,2573 | −4 000 | −81 | 93 432 | ||||
| 2015-03-20 | 2015-03-20 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,0670 | −740 | −15 | 97 432 | ||||
| 2015-03-20 | 2015-03-19 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,0086 | −1 315 | −26 | 98 172 | ||||
| 2015-03-20 | 2015-03-18 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,0309 | −1 124 | −23 | 99 487 | ||||
| 2015-03-17 | 2015-03-17 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,0908 | −738 | −15 | 100 611 | ||||
| 2015-03-17 | 2015-03-16 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,0300 | −3 | −0 | 101 349 | ||||
| 2015-03-17 | 2015-03-16 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,0100 | −80 | −2 | 101 352 | ||||
| 2015-03-11 | 2015-03-10 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,3003 | −2 537 | −52 | 101 432 | ||||
| 2015-03-11 | 2015-03-09 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,1034 | −1 463 | −29 | 103 969 | ||||
| 2015-03-05 | 2015-03-03 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −2 041 | 18 953 | |||||
| 2015-03-05 | 2015-03-03 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −359 | 359 | |||||
| 2015-03-05 | 2015-03-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 20,0292 | −2 400 | −48 | 22 487 | ||||
| 2015-03-05 | 2015-03-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 2 400 | 3 | 24 887 | ||||
| 2015-03-05 | 2015-03-03 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,0689 | −1 129 | −23 | 105 432 | ||||
| 2015-03-02 | 2015-03-02 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,1144 | −2 871 | −58 | 106 561 | ||||
| 2015-02-27 | 2015-02-25 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,2471 | −8 000 | −162 | 109 432 | ||||
| 2015-02-04 | 2015-02-03 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −3 501 | 20 994 | |||||
| 2015-02-04 | 2015-02-03 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −1 499 | 718 | |||||
| 2015-02-04 | 2015-02-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 18,0984 | −371 | −7 | 22 487 | ||||
| 2015-02-04 | 2015-02-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 17,3408 | −4 629 | −80 | 22 858 | ||||
| 2015-02-04 | 2015-02-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 5 000 | 6 | 27 487 | ||||
| 2015-01-29 | 2015-01-27 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 17,2500 | 145 000 | 2 501 | 2 139 568 | ||||
| 2015-01-29 | 2015-01-27 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 17,2500 | 145 000 | 2 501 | 2 139 568 | ||||
| 2015-01-27 | 2015-01-27 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 17,2500 | 5 500 | 95 | 10 500 | ||||
| 2015-01-26 | 2015-01-22 | 4/A | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 17,2500 | 55 000 | 949 | 2 271 558 | ||||
| 2015-01-26 | 2015-01-22 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 17,2500 | 55 000 | 949 | 2 271 558 | ||||
| 2015-01-26 | 2015-01-22 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 17,2500 | 55 000 | 949 | 2 271 558 | ||||
| 2015-01-13 | 2015-01-12 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 22,8545 | −4 000 | −91 | 117 432 | ||||
| 2015-01-07 | 2015-01-05 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −5 000 | 2 217 | |||||
| 2015-01-07 | 2015-01-05 | 4 | Westberg Paul | VSAR | Common Stock | D | 23,3347 | −1 270 | −30 | 22 487 | ||||
| 2015-01-07 | 2015-01-05 | 4 | Westberg Paul | VSAR | Common Stock | D | 22,1893 | −3 730 | −83 | 23 757 | ||||
| 2015-01-07 | 2015-01-05 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 5 000 | 6 | 27 487 | ||||
| 2015-01-07 | 2015-01-05 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 21,9692 | −3 800 | −83 | 121 432 | ||||
| 2015-01-07 | 2015-01-05 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 21,2900 | −200 | −4 | 125 232 | ||||
| 2014-12-30 | 2014-12-26 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 22,24 | 8 860 | 8 860 | |||||
| 2014-12-30 | 2014-12-26 | 4 | Westberg Paul | VSAR | Common Stock | D | 3 797 | 22 487 | ||||||
| 2014-12-30 | 2014-12-26 | 4 | Brumm Joshua T | VSAR | Stock Option (Right to Buy) | D | 22,24 | 24 373 | 24 373 | |||||
| 2014-12-30 | 2014-12-26 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 10 445 | 36 635 | ||||||
| 2014-12-30 | 2014-12-29 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 22,1054 | −4 000 | −88 | 125 432 | ||||
| 2014-12-30 | 2014-12-26 | 4 | Cleland Jeffrey L | VSAR | Stock Option (Right to Buy) | D | 22,24 | 75 041 | 75 041 | |||||
| 2014-12-30 | 2014-12-26 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 32 160 | 129 432 | ||||||
| 2014-12-22 | 2014-12-22 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 21,3561 | −5 870 | −125 | 97 272 | ||||
| 2014-12-22 | 2014-12-22 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,5364 | −2 110 | −43 | 103 142 | ||||
| 2014-12-22 | 2014-12-19 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20,0000 | −20 | −0 | 105 252 | ||||
| 2014-12-22 | 2014-11-14 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | −1 900 | 105 272 | ||||||
| 2014-12-22 | 2014-12-18 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 19,0123 | −150 000 | −2 852 | 2 409 374 | ||||
| 2014-12-15 | 2014-12-12 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −3 054 | 7 217 | |||||
| 2014-12-15 | 2014-12-12 | 4 | Westberg Paul | VSAR | Common Stock | D | 18,6542 | −3 054 | −57 | 18 690 | ||||
| 2014-12-15 | 2014-12-12 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 3 054 | 4 | 21 744 | ||||
| 2014-12-15 | 2014-12-11 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1,26 | −6 946 | 10 271 | |||||
| 2014-12-15 | 2014-12-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 18,5100 | −6 946 | −129 | 18 690 | ||||
| 2014-12-15 | 2014-12-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 1,2650 | 6 946 | 9 | 25 636 | ||||
| 2014-12-11 | 3 | GREER R SCOTT | VSAR | Common Stock | D | 10 000 | ||||||||
| 2014-12-11 | 3 | GREER R SCOTT | VSAR | Common Stock | D | 10 000 | ||||||||
| 2014-12-11 | 2014-12-09 | 4 | GREER R SCOTT | VSAR | Stock Option (right to Buy) | D | 18,66 | 35 000 | 35 000 | |||||
| 2014-11-25 | 2014-11-24 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18,0164 | −138 | −2 | 19 161 | ||||
| 2014-11-25 | 2014-11-24 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18,0164 | −1 480 | −27 | 205 968 | ||||
| 2014-11-25 | 2014-11-24 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18,0164 | −15 589 | −281 | 2 169 931 | ||||
| 2014-11-24 | 2014-11-21 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18,0388 | −214 | −4 | 19 299 | ||||
| 2014-11-24 | 2014-11-21 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18,0388 | −2 304 | −42 | 207 448 | ||||
| 2014-11-24 | 2014-11-21 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18,0388 | −24 275 | −438 | 2 185 520 | ||||
| 2014-11-21 | 2014-11-20 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18,3205 | −72 | −1 | 19 513 | ||||
| 2014-11-21 | 2014-11-20 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18,3205 | −774 | −14 | 209 752 | ||||
| 2014-11-21 | 2014-11-20 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18,3205 | −8 154 | −149 | 2 209 795 | ||||
| 2014-11-20 | 2014-11-18 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19,3823 | −1 531 | −30 | 19 585 | ||||
| 2014-11-20 | 2014-11-18 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19,3823 | −16 456 | −319 | 210 526 | ||||
| 2014-11-20 | 2014-11-18 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19,3823 | −173 375 | −3 360 | 2 217 949 | ||||
| 2014-11-17 | 2014-11-13 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19,4322 | −99 | −2 | 21 116 | ||||
| 2014-11-17 | 2014-11-13 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19,4322 | −1 070 | −21 | 226 982 | ||||
| 2014-11-17 | 2014-11-13 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19,4322 | −11 269 | −219 | 2 391 324 | ||||
| 2014-11-14 | 2014-11-12 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19,4210 | −290 | −6 | 21 215 | ||||
| 2014-11-14 | 2014-11-12 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19,4210 | −3 113 | −60 | 228 052 | ||||
| 2014-11-14 | 2014-11-12 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19,4210 | −32 797 | −637 | 2 402 593 | ||||
| 2014-11-13 | 2014-11-11 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 19,3700 | −800 000 | −15 496 | 2 559 374 | ||||
| 2014-10-01 | 2014-09-29 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 20,0168 | −12 556 | −251 | 3 359 374 | ||||
| 2014-06-13 | 2014-06-11 | 4 | Brumm Joshua T | VSAR | Stock Option (Right to Buy) | D | 31,96 | 32 000 | 32 000 | |||||
| 2014-06-13 | 2014-06-11 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 15 000 | 25 000 | ||||||
| 2014-06-13 | 2014-06-11 | 4 | Cleland Jeffrey L | VSAR | Stock Option (Right to Buy) | D | 31,96 | 100 000 | 100 000 | |||||
| 2014-06-13 | 2014-06-11 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 30 000 | 146 280 | ||||||
| 2014-06-13 | 2014-06-11 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 31,96 | 25 000 | 25 000 | |||||
| 2014-06-13 | 2014-06-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 7 500 | 17 500 | ||||||
| 2014-04-17 | 2014-04-15 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 10 000 | 10 000 | ||||||
| 2014-04-17 | 2014-04-15 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 10 000 | 116 280 | ||||||
| 2014-04-17 | 2014-04-15 | 4 | Westberg Paul | VSAR | Common Stock | D | 10 000 | 10 000 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series B Convertible Preferred Stock | D | 0,00 | −759 565 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Warrant | D | 0,45 | −759 565 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series E Convertible Preferred Stock | D | 0,00 | −3 546 094 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series D2 Convertible Preferred Stock | D | 0,00 | −1 349 433 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series D1 Convertible Preferred Stock | D | 0,00 | −3 050 019 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series C Convertible Preferred Stock | D | 0,00 | −8 439 620 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series B Convertible Preferred Stock | D | 0,00 | −20 942 466 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 21,0200 | 60 000 | 1 261 | 3 371 930 | ||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 66 049 | 3 311 930 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 308 356 | 3 245 881 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 117 342 | 2 937 525 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 265 219 | 2 820 183 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 733 880 | 2 554 964 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 1 821 084 | 1 821 084 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Series E Convertible Preferred Stock | D | −485 664 | 0 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Series D-2 Convertible Preferred Stock | D | −802 596 | 0 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Series D-1 Convertible Preferred Stock | D | −775 315 | 0 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Series B Convertible Preferred Stock | D | −23 403 | 0 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 21,0000 | 60 000 | 1 260 | 2 146 978 | ||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 485 664 | 2 086 978 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 802 596 | 1 601 314 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 775 315 | 798 718 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 23 403 | 23 403 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series E Convertible Preferred Stock | I | −1 773 049 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series D-2 Convertible Preferred Stock | I | −899 619 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series D-1 Convertible Preferred Stock | I | −2 033 350 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series C Convertible Preferred Stock | I | −5 626 413 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series B Convertible Preferred Stock | I | −14 468 020 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series B Convertible Preferred Stock | I | 506 376 | 14 468 020 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Warrants to Purchase Series B Preferred Stock | I | 0,45 | −506 376 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 21,0000 | 60 000 | 1 260 | 2 216 558 | ||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 154 178 | 2 156 558 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 78 228 | 2 002 380 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 176 813 | 1 924 152 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 489 253 | 1 747 339 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 1 258 086 | 1 258 086 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Series E Convertible Preferred Stock | I | −5 486 820 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Series D-2 Convertible Preferred Stock | I | −654 796 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Series D-1 Convertible Preferred Stock | I | −1 479 993 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Series C Convertible Preferred Stock | I | −14 222 222 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Series B Convertible Preferred Stock | I | −403 704 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 21,0000 | 60 000 | 1 260 | 1 994 568 | ||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 477 115 | 1 934 568 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 56 939 | 1 457 453 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 128 695 | 1 400 514 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 1 236 715 | 1 271 819 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 35 104 | 35 104 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Series E Convertible Preferred Stock | I | −5 486 820 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Series D-2 Convertible Preferred Stock | I | −654 796 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Series D-1 Convertible Preferred Stock | I | −1 479 993 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Series C Convertible Preferred Stock | I | −14 222 222 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Series B Convertible Preferred Stock | I | −403 704 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 21,0000 | 60 000 | 1 260 | 1 994 568 | ||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 477 115 | 1 934 568 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 56 939 | 1 457 453 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 128 695 | 1 400 514 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 1 236 715 | 1 271 819 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 35 104 | 35 104 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5,18 | −510 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5,18 | 510 | 510 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Series B Convertible Preferred Stock | D | 0,45 | −5 872 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-2 Convertible Preferred Stock | D | −5 796 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-1 Convertible Preferred Stock | D | −13 040 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series C Convertible Preferred Stock | D | −65 250 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Seires B Convertible Preferred Stock | D | −70 792 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series A Convertible Preferred Stock | D | −88 000 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5,18 | −5 489 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5,18 | 5 489 | 5 489 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Series B Convertible Preferred Stock | D | 0,45 | −63 127 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-2 Convertible Preferred Stock | D | −62 297 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-1 Convertible Preferred Stock | D | −140 174 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series C Convertible Preferred Stock | D | −701 432 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series B Convertible Prefered Stock | D | −760 994 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series A Convertible Preferred Stock | D | −945 973 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5,18 | −57 831 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5,18 | 57 831 | 57 831 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Series B Convertible Preferred Stock | D | 0,45 | −665 057 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-2 Convertible Preferred Stock | D | −656 313 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-1 Convertible Preferred Stock | D | −1 476 754 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series C Convertible Preferred Stock | D | −7 389 507 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series B Convertible Preferred Stock | D | −8 017 215 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series A Convertible Preferred Stock | D | −9 966 027 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 384 | 21 503 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 21 119 | 21 119 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 4 136 | 231 168 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 227 032 | 227 032 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 43 579 | 2 435 389 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 2 391 810 | 2 391 810 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series E Convertible Preferred Stock | I | −1 773 049 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series D-2 Convertible Preferred Stock | I | −899 619 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series D-1 Convertible Preferred Stock | I | −2 033 350 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series C Convertible Preferred Stock | I | −5 626 413 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series B Convertible Preferred Stock | I | −14 468 020 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series B Convertible Preferred Stock | I | 506 376 | 14 468 020 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Warrants to Purchase Series B Preferred Stock | I | 0,45 | −506 376 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 21,0000 | 60 000 | 1 260 | 2 216 558 | ||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 154 178 | 2 156 558 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 78 228 | 2 002 380 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 176 813 | 1 924 152 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 489 253 | 1 747 339 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 1 258 086 | 1 258 086 | ||||||
| 2014-03-24 | 2014-03-20 | 4 | AKKARAJU SRINIVAS | VSAR | Stock Option (Right to Buy) | D | 21,00 | 35 000 | 35 000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | Malik Shahzad | VSAR | Stock Option (Right to Buy) | D | 21,00 | 35 000 | 35 000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | JENNINGS EDMON R | VSAR | Stock Option (Right to Buy) | D | 21,00 | 35 000 | 35 000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | SUN ANTHONY Y | VSAR | Stock Option (Right to Buy) | D | 21,00 | 35 000 | 35 000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | Varian John | VSAR | Stock Option (Right to Buy) | D | 21,00 | 35 000 | 35 000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | Dybbs Michael | VSAR | Stock Option (Right to Buy) | D | 21,00 | 35 000 | 35 000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | De Rubertis Francesco | VSAR | Stock Option (Right to Buy) | D | 21,00 | 35 000 | 35 000 | |||||
| 2014-03-20 | 3 | Varian John | VSAR | Common Stock | D | 0 | ||||||||
| 2014-03-20 | 3 | De Rubertis Francesco | VSAR | Common Stock | D | 0 | ||||||||
| 2014-03-20 | 3 | Cleland Jeffrey L | VSAR | Common Stock | D | 212 560 | ||||||||
| 2014-03-20 | 3 | Cleland Jeffrey L | VSAR | Common Stock | D | 212 560 |
P
Köp på öppna marknaden eller privat köp av icke-derivatsäkerhet
S
Köp på öppna marknaden eller privat försäljning av icke-derivatsäkerhet
A
Bevilja, tilldelning eller annat förvärv av värdepapper från företaget (såsom en option)
C
Omvandling av derivat
D
Försäljning eller överföring av värdepapper tillbaka til företaget
F
Betalning av lösenpris eller skatteskuld med del av värdepapper som erhållits från bolaget
G
Överlåtelse av värdepapper från eller till insidern
K
Aktieswappar och liknande säkringsaffärer
M
Utövande eller omvandling av derivatsäkerhet som erhållits från företaget (som en option)
V
En transaktion friviligt rapporterad på schema 4
J
Andra (med en fotnot som beskriver transaktionen)
