Market Value1,719,016,000
Total Holdings293
File Date2017-02-14
Original Filing (Click here)

All hedge funds or institutions that manage over $100M are required by the SEC to file quarterly reports on their holdings. These reports are called 13F reports. However, the filings are required the following quarter from the reporting period, which means that by the time the filing is made (and we see them), the information could be five months old.

For funds with long term positions that make few trades, the holdings might closely resemble their current holdings, even after several months. However, for funds that have high turnover, the holdings data we see might differ significantly from their current holdings. Institutions are required to report CALL and PUT options, and those positions are identified in the table. However, they are not required to report short positions.

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Security Imputed
Share Price
Prev
Shares
Current
Shares
Change
(Percent)
Prev Value
(USD x1000)
Current Value
(USD x1000)
Change
(Percent)
TPST / Tempest Therapeutics, Inc.
ADXS / Ayala Pharmaceuticals, Inc. Call
ADXS / Ayala Pharmaceuticals, Inc.
AGIO / Agios Pharmaceuticals, Inc. Call
ADVM / Adverum Biotechnologies, Inc.
TSRO / TESARO, Inc. Call
TSRO / TESARO, Inc. Put
NVAX / Novavax, Inc. Call
RIGL / Rigel Pharmaceuticals, Inc. Call
INSM / Insmed Incorporated
INSM / Insmed Incorporated Call
INSM / Insmed Incorporated Put
SCMP / Sucampo Pharmaceuticals, Inc.
MTFBW / Motif Bio plc Warrants
SCON / Superconductor Technologies Inc.
WINT / Windtree Therapeutics, Inc.
EXEL / Exelixis, Inc. Call
HCA / HCA Healthcare, Inc. Put
TENX / Tenax Therapeutics, Inc. Call
TENX / Tenax Therapeutics, Inc. Put
ALQA / Alliqua, Inc.
MTFB / Motif Bio plc ADRs
DERM / Journey Medical Corporation Put
NTRA / Natera, Inc. Call
GNVC / GenVec, Inc.
ADHD / Alcobra Ltd. Put
THC / Tenet Healthcare Corporation
MDGN / Medgenics, Inc.
ABUS / Arbutus Biopharma Corporation
CHRS / Coherus Oncology, Inc.
MRK / Merck & Co., Inc. Call
SYN / Synthetic Biologics Inc
UTHR / United Therapeutics Corporation Call
UTHR / United Therapeutics Corporation Put
UTHR / United Therapeutics Corporation
BDSI / Biodelivery Sciences International Call
LLY / Eli Lilly and Company Call
LLY / Eli Lilly and Company Put
PSDV / pSivida Corp.
ZSAN / Zosano Pharma Corp
DRNA / Dicerna Pharmaceuticals Inc
LJPC / La Jolla Pharmaceutical Co. Call
MDGN / Medgenics, Inc. Call
NUROW / NeuroMetrix, Inc. Warrants
SGYPW / Synergy Pharmaceuticals, Inc., Warrants
AEZS / COSCIENS Biopharma Inc. Put
INCY / Incyte Corporation Call
US0153511094 / Alexion Pharmaceuticals, Inc. Call
LUMO / Lumos Pharma, Inc. Call
LUMO / Lumos Pharma, Inc. Put
NKTR / Nektar Therapeutics Call
CYH / Community Health Systems, Inc.
OPK / OPKO Health, Inc. Call
OPK / OPKO Health, Inc. Put
ENDP / Endo International plc
LRMR / Larimar Therapeutics, Inc.
LRMR / Larimar Therapeutics, Inc. Call
HUM / Humana Inc. Call
HUM / Humana Inc. Put
IL0011177958 / Intec Pharma Ltd
PTN / Palatin Technologies, Inc.
ARMP / Armata Pharmaceuticals, Inc.
SIOX / Sio Gene Therapies Inc.
SIOX / Sio Gene Therapies Inc. Call
SIOX / Sio Gene Therapies Inc. Put
ARCT / Arcturus Therapeutics Holdings Inc.
HALO / Halozyme Therapeutics, Inc. Call
HALO / Halozyme Therapeutics, Inc. Put
ONCS / OncoSec Medical Inc
61166W101 / Monsanto Co. Call
STML / Stemline Therapeutics, Inc. Call
STML / Stemline Therapeutics, Inc.
PCRX / Pacira BioSciences, Inc. Call
PCRX / Pacira BioSciences, Inc. Put
APDNW / Applied DNA Sciences, Inc., Warrants
ABT / Abbott Laboratories Call
ABT / Abbott Laboratories Put
FOLD / Amicus Therapeutics, Inc. Put
MDCO / Medicines Company
MDCO / Medicines Company Put
ALNY / Alnylam Pharmaceuticals, Inc.
ALNY / Alnylam Pharmaceuticals, Inc. Call
ALNY / Alnylam Pharmaceuticals, Inc. Put
VNDA / Vanda Pharmaceuticals Inc. Call
GNMX / Aevi Genomic Medicine, Inc.
CLVS / Clovis Oncology Inc Put
CLVS / Clovis Oncology Inc Call
92686J114 / Viking Therapeutics, Inc. Warrants exp. 2021-04-04
SLS / SELLAS Life Sciences Group, Inc. Put
ITCI / Intra-Cellular Therapies, Inc.
ITCI / Intra-Cellular Therapies, Inc. Call
ITCI / Intra-Cellular Therapies, Inc. Put
PBYI / Puma Biotechnology, Inc. Call
RDUS / Radius Recycling, Inc. Call
HZNP / Horizon Therapeutics Plc Call
ALPN / Alpine Immune Sciences, Inc.
/ Zephyr Energy PLC
ABUS / Arbutus Biopharma Corporation Call
CRDC / Cardica, Inc.
SIEN / Sientra, Inc. Put
ONTY / Oncothyreon, Inc.
WGBS / WaferGen Bio-Systems, Inc.
BDSI / Biodelivery Sciences International
VCEL / Vericel Corporation
ONSIZ / Oncobiologics, Inc. Series B Warrant Expiring 5/18
AERI / Aerie Pharmaceuticals Inc Call
CHRS / Coherus Oncology, Inc. Put
LJPC / La Jolla Pharmaceutical Co. Put
ABT / Abbott Laboratories
CLRBW / Cellectar Biosciences, Inc. Warrants expiring 8/20/2019
ATHX / Athersys, Inc.
ZGNX / Zogenix Inc Put
AVXS / AveXis, Inc.
ACHC / Acadia Healthcare Company, Inc. Put
NBSE / NeuBase Therapeutics, Inc.
TGTX / TG Therapeutics, Inc. Put
MDCO / Medicines Company Call
0PP / Portola Pharmaceuticals Inc Call
EXEL / Exelixis, Inc. Put
CSBR / Champions Oncology, Inc.
IOVA / Iovance Biotherapeutics, Inc. Call
DXCM / DexCom, Inc. Call
VXZ / iPath Series B S&P 500 VIX Mid-Term Futures ETN - Corporate Bond/Note
CYTX / Cytori Therapeutics, Inc.
GENE / Genetic Technologies Limited - Depositary Receipt (Common Stock)
SYBX / Synlogic, Inc.
NDRM / NeuroDerm Ltd.
ELDN / Eledon Pharmaceuticals, Inc.
QRHC / Quest Resource Holding Corporation
RIGL / Rigel Pharmaceuticals, Inc.
BNTCW / Benitec Biopharma Ltd
ROKA / Roka Bioscience, Inc.
SHPG / Shire Plc. Put
VCYT / Veracyte, Inc.
EIGR / Eiger BioPharmaceuticals, Inc.
NONOF / Novo Nordisk A/S Put
SHPG / Shire Plc.
US60877T1007 / Momenta Pharmaceuticals, Inc. Call
BMYMP / Bristol-Myers Squibb Company - Preferred Security Call
HZNP / Horizon Therapeutics Plc Put
/ Immunomedics, Inc.
ZGNX / Zogenix Inc Call
ZGNX / Zogenix Inc
MLNT / Melinta Therapeutics, Inc.
CBMX / CombiMatrix Corp.
ONSIW / Oncobiologics, Inc. Series A Warrant Expiring 2/18/2018
IOVA / Iovance Biotherapeutics, Inc. Put
SRRA / Sierra Oncology Inc
45779A119 / InspireMD, Inc. Warrants
IOVA / Iovance Biotherapeutics, Inc.
RGLS / Regulus Therapeutics Inc. Call
RGNX / REGENXBIO Inc.
CMRX / Chimerix, Inc.
US00C4U1L353 / Mylan N.V. Call
KITE / Kite Pharma, Inc. Put
SIEN / Sientra, Inc.
FWP / Forward Pharma A/S - ADR
ANTH / Anthera Pharmaceuticals, Inc.
74979C113 / RXI Pharmaceuticals Corporation, Warrants
LJPC / La Jolla Pharmaceutical Co.
FOMX / Foamix Pharmaceuticals Ltd. Call
RCKT / Rocket Pharmaceuticals, Inc.
SPDR S&P BIOTECH ETF / ETF Put (78464A950)
68232V116 / Onconova Therapeutics, Inc. Warrants
CEMP / Cempra, Inc. Put
NTLA / Intellia Therapeutics, Inc.
CRME / Cardiome Pharma Corp.
CYTXW / Cytori Therapeutics, Inc. Warrants
AVXL / Anavex Life Sciences Corp. Put
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Call
ADHD / Alcobra Ltd. Call
DRWIW / Dragonwave, Inc.
FOMX / Foamix Pharmaceuticals Ltd.
CEMP / Cempra, Inc. Call
ACHC / Acadia Healthcare Company, Inc. Call
US00448Q2012 / Achillion Pharmaceuticals, Inc. Put
SHPG / Shire Plc. Call
FOLD / Amicus Therapeutics, Inc.
JUNO / Juno Therapeutics, Inc. Call
PARN / Parnell Pharmaceuticals Holdings Ltd.
FOLD / Amicus Therapeutics, Inc. Call
KITE / Kite Pharma, Inc. Call
BMY / Bristol-Myers Squibb Company
ACUR / Acura Pharmaceuticals, Inc.
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock) Call
ANTH / Anthera Pharmaceuticals, Inc. Call
BMYMP / Bristol-Myers Squibb Company - Preferred Security Put
OCRX / Ocera Therapeutics, Inc.
LUMO / Lumos Pharma, Inc.
ACOR / Acorda Therapeutics, Inc.
CLRB / Cellectar Biosciences, Inc.
EXAS / Exact Sciences Corporation Put
XBI / SPDR Series Trust - SPDR S&P Biotech ETF
CALA / Calithera Biosciences, Inc.
ADMS / Adamas Pharmaceuticals Inc
451731103 / Ignyta, Inc.
PVCT / Provectus Biopharmaceuticals, Inc.
PRTK / Paratek Pharmaceuticals Inc.
REGN / Regeneron Pharmaceuticals, Inc.
REGN / Regeneron Pharmaceuticals, Inc. Call
REGN / Regeneron Pharmaceuticals, Inc. Put
BNTC / Benitec Biopharma Inc.
ACAD / ACADIA Pharmaceuticals Inc. Call
HES / Hess Corporation Call
RDUS / Radius Recycling, Inc. Put
INFI / Infinity Pharmaceuticals Inc. Call
AEZS / COSCIENS Biopharma Inc.
BIOC / Biocept Inc
OCUL / Ocular Therapeutix, Inc.
ACAD / ACADIA Pharmaceuticals Inc. Put
EDIT / Editas Medicine, Inc.
SGYPQ / SYNERGY PHARMACEUTICALS INC DEL Call
ASRT / Assertio Holdings, Inc. Call
RNVAZ / Rennova Health, Inc. Warrants
NVIV / InVivo Therapeutics Holdings Corp. Call
/ GW Pharmaceuticals Plc. Put
/ GW Pharmaceuticals Plc. Call
FGEN / FibroGen, Inc. Call
FGEN / FibroGen, Inc.
PRTA / Prothena Corporation plc Call
GALT / Galectin Therapeutics Inc. Put
CAPR / Capricor Therapeutics, Inc.
VRTX / Vertex Pharmaceuticals Incorporated Call
RIBT / RiceBran Technologies
OPGN / OpGen, Inc.
SRPT / Sarepta Therapeutics, Inc.
SRPT / Sarepta Therapeutics, Inc. Call
SRPT / Sarepta Therapeutics, Inc. Put
ATHX / Athersys, Inc. Put
AMGN / Amgen Inc.
AMGN / Amgen Inc. Call
AMGN / Amgen Inc. Put
DERM / Journey Medical Corporation Call
CDTX / Cidara Therapeutics, Inc.
ACOR / Acorda Therapeutics, Inc. Call
ACOR / Acorda Therapeutics, Inc. Put
SGYPQ / SYNERGY PHARMACEUTICALS INC DEL Put
VYNT / Vyant Bio, Inc.
TNXP / Tonix Pharmaceuticals Holding Corp.
BCLI / Brainstorm Cell Therapeutics Inc.
ABBV / AbbVie Inc. Call
CELG / Celgene Corp. Call
CELG / Celgene Corp.
CELG / Celgene Corp. Put
AGEN / Agenus Inc. Put
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Call
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Put
DRRX / DURECT Corporation
DRRX / DURECT Corporation Call
PIRS / Pieris Pharmaceuticals, Inc.
LLY / Eli Lilly and Company
NVAX / Novavax, Inc. Put
OTLK / Outlook Therapeutics, Inc.
BIIB / Biogen Inc.
BIIB / Biogen Inc. Put
BLPH / Bellerophon Therapeutics, Inc.
IMUC / EOM Pharmaceuticals Holdings, Inc.
ENDP / Endo International plc Put
TXMD / TherapeuticsMD, Inc. Call
TXMD / TherapeuticsMD, Inc. Put
VRTX / Vertex Pharmaceuticals Incorporated Put
ESRX / Express Scripts Holding Co.
ESRX / Express Scripts Holding Co. Call
ESRX / Express Scripts Holding Co. Put
0PP / Portola Pharmaceuticals Inc Put
GPL / Great Panther Mining Ltd
KPRX / Kiora Pharmaceuticals, Inc.
OCX / OncoCyte Corporation Call
SPHS / Sophiris Bio Inc
QNRX / Quoin Pharmaceuticals, Ltd. - Depositary Receipt (Common Stock)
ISEE / IVERIC bio Inc Call
BCRX / BioCryst Pharmaceuticals, Inc. Call
FWBI / First Wave BioPharma, Inc.
GPL / Great Panther Mining Ltd Put
OTIC / Otonomy Inc
PBYI / Puma Biotechnology, Inc.
PBYI / Puma Biotechnology, Inc. Put
TSRO / TESARO, Inc.
GILD / Gilead Sciences, Inc. Call
HCA / HCA Healthcare, Inc. Call
IONS / Ionis Pharmaceuticals, Inc. Put
IONS / Ionis Pharmaceuticals, Inc. Call
EVOK / Evoke Pharma, Inc.
IMUC.WS / ImmunoCellular Therapeutics, Ltd., Warrants
ASMB / Assembly Biosciences, Inc.
BIIB / Biogen Inc. Call
OCGN / Ocugen, Inc.
TXMD / TherapeuticsMD, Inc.
ABBV / AbbVie Inc. Put
GILD / Gilead Sciences, Inc. Put
TMBR / Timber Pharmaceuticals Inc
FLXN / Horizon Funds - Horizon Flexible Income ETF
FLXN / Horizon Funds - Horizon Flexible Income ETF Call
FLXN / Horizon Funds - Horizon Flexible Income ETF Put
THC / Tenet Healthcare Corporation Call
THC / Tenet Healthcare Corporation Put
MRTX / Mirati Therapeutics, Inc.
GBT / Global Blood Therapeutics Inc. Call
OPK / OPKO Health, Inc.
ONTX / Onconova Therapeutics, Inc.
PALI / Palisade Bio, Inc.
RNVA / Rennova Health, Inc.
GALT / Galectin Therapeutics Inc.
PRQR / ProQR Therapeutics N.V.
LXRX / Lexicon Pharmaceuticals, Inc.
PHIO / Phio Pharmaceuticals Corp.
LXRX / Lexicon Pharmaceuticals, Inc. Call
LXRX / Lexicon Pharmaceuticals, Inc. Put
TVTX / Travere Therapeutics, Inc. Call
TVTX / Travere Therapeutics, Inc. Put
VTGN / Vistagen Therapeutics, Inc.
VTVT / vTv Therapeutics Inc.
MDGS / Medigus Ltd. - Depositary Receipt (Common Stock)
CHEK / Check-Cap Ltd.
US00448Q2012 / Achillion Pharmaceuticals, Inc. Call
OCUP / Opus Genetics, Inc.
BLUE / bluebird bio, Inc. Call
BPTH / Bio-Path Holdings, Inc.
SLNO / Soleno Therapeutics, Inc.
TENX / Tenax Therapeutics, Inc.
CYH / Community Health Systems, Inc. Put
HRTX / Heron Therapeutics, Inc. Call
SGMO / Sangamo Therapeutics, Inc.
SGMO / Sangamo Therapeutics, Inc. Call
RSLS / ReShape Lifesciences Inc.
CVM / CEL-SCI Corporation
MNKD / MannKind Corporation
MNKD / MannKind Corporation Put
RCKT / Rocket Pharmaceuticals, Inc. Call
RCKT / Rocket Pharmaceuticals, Inc. Put
NVRO / Nevro Corp. Call
BPMC / Blueprint Medicines Corporation Put
PTCT / PTC Therapeutics, Inc. Put
SAGE / Sage Therapeutics, Inc. Call
SAGE / Sage Therapeutics, Inc. Put
PTCT / PTC Therapeutics, Inc. Call
ALKS / Alkermes plc Call
NUWE / Nuwellis, Inc.
VIRX / Viracta Therapeutics, Inc.
SLS / SELLAS Life Sciences Group, Inc.
ENLV / Enlivex Therapeutics Ltd.
SSKN / STRATA Skin Sciences, Inc.
EDAP / EDAP TMS S.A. - Depositary Receipt (Common Stock)
EDAP / EDAP TMS S.A. - Depositary Receipt (Common Stock) Put
NBIX / Neurocrine Biosciences, Inc. Call
XTLB / XTL Biopharmaceuticals Ltd. - Depositary Receipt (Common Stock)
DVAX / Dynavax Technologies Corporation
DVAX / Dynavax Technologies Corporation Call
DVAX / Dynavax Technologies Corporation Put
AIM / AIM ImmunoTech Inc.
AKTX / Akari Therapeutics, Plc - Depositary Receipt (Common Stock)
APDN / Applied DNA Sciences, Inc.
ARAV / Aravive, Inc.
SPY / SPDR S&P 500 ETF Put
ATNM / Actinium Pharmaceuticals, Inc.
RDHL / RedHill Biopharma Ltd. - Depositary Receipt (Common Stock)
ADXS / Ayala Pharmaceuticals, Inc. Put
SRNE / Sorrento Therapeutics, Inc. Call
SRNE / Sorrento Therapeutics, Inc.
NURO / NeuroMetrix, Inc.
CLSN / Imunon Inc
KPRX / Kiora Pharmaceuticals, Inc.
ADMP / Adamis Pharmaceuticals Corp Put
CYTR / LadRx Corp
OEF / iShares Trust - iShares S&P 100 ETF Call
OEF / iShares Trust - iShares S&P 100 ETF Put
SPY / SPDR S&P 500 ETF Call