Market Value2,268,048,000
Total Holdings230
File Date2021-02-12
Original Filing (Click here)

All hedge funds or institutions that manage over $100M are required by the SEC to file quarterly reports on their holdings. These reports are called 13F reports. However, the filings are required the following quarter from the reporting period, which means that by the time the filing is made (and we see them), the information could be five months old.

For funds with long term positions that make few trades, the holdings might closely resemble their current holdings, even after several months. However, for funds that have high turnover, the holdings data we see might differ significantly from their current holdings. Institutions are required to report CALL and PUT options, and those positions are identified in the table. However, they are not required to report short positions.

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Security Imputed
Share Price		 Prev
Shares		 Current
Shares		 Change
(Percent)		 Prev Value
(USD x1000)		 Current Value
(USD x1000)		 Change
(Percent)
GBT / Global Blood Therapeutics Inc. Put
PCVX / Vaxcyte, Inc.
ETNB / 89bio, Inc.
KRTX / Karuna Therapeutics, Inc. Call
MRTX / Mirati Therapeutics, Inc.
APLS / Apellis Pharmaceuticals, Inc.
MDGL / Madrigal Pharmaceuticals, Inc. Call
ITCI / Intra-Cellular Therapies, Inc.
ITCI / Intra-Cellular Therapies, Inc. Put
CCCC / C4 Therapeutics, Inc.
STTK / Shattuck Labs, Inc.
PSTX / Poseida Therapeutics, Inc.
IMAB / I-Mab - Depositary Receipt (Common Stock)
XBI / SPDR Series Trust - SPDR S&P Biotech ETF Call
PRTA / Prothena Corporation plc
BDTX / Black Diamond Therapeutics, Inc.
DTIL / Precision BioSciences, Inc.
ALBO / Albireo Pharma Inc
ARYBU / ARYA Sciences Acquisition Corp II
ADVM / Adverum Biotechnologies, Inc. Call
FREQ / Frequency Therapeutics Inc Put
TBIO / Telesis Bio, Inc. Put
/ Pandion Therapeutics Inc
HST / Host Hotels & Resorts, Inc. Put
EPZM / Epizyme Inc
ATRA / Atara Biotherapeutics, Inc.
IGMS / IGM Biosciences, Inc. Put
ALPN / Alpine Immune Sciences, Inc.
NBIX / Neurocrine Biosciences, Inc. Call
SLNO / Soleno Therapeutics, Inc.
ABUS / Arbutus Biopharma Corporation
MBIO / Mustang Bio, Inc.
GWP / GW Pharmaceuticals plc
TCDA / Tricida Inc
GWP / GW Pharmaceuticals plc Put
SAGE / Sage Therapeutics, Inc.
TARA / Protara Therapeutics, Inc.
INCY / Incyte Corporation Put
PANA / Panacea Acquisition Corp II - Class A
CMRX / Chimerix, Inc.
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Call
ARGX / argenx SE - Depositary Receipt (Common Stock) Put
SIOX / Sio Gene Therapies Inc.
CYRX / Cryoport, Inc.
CYRX / Cryoport, Inc. Call
CYRX / Cryoport, Inc. Put
RETA / Reata Pharmaceuticals Inc - Class A Call
RETA / Reata Pharmaceuticals Inc - Class A Put
ARWR / Arrowhead Pharmaceuticals, Inc. Put
XLRN / Acceleron Pharma Inc Put
US5431951012 / Longview Acquisition Corp.
CEMI / Chembio Diagnostics Inc.
ASND / Ascendis Pharma A/S - Depositary Receipt (Common Stock)
ASND / Ascendis Pharma A/S - Depositary Receipt (Common Stock) Call
DCPH / Deciphera Pharmaceuticals, Inc. Call
US85789A1051 / STEALTH BIOTHERAPEUTICS CORP ADR
BTAI / BioXcel Therapeutics, Inc.
CLOV / Clover Health Investments, Corp. Call
US16706W1027 / Chiasma Inc
SBBP / Strongbridge Biopharma plc
CHAQ.U / Chardan Healthcare Acquisition 2 Corp. Units, each consisting of one share of , and one
KDMN / Kadmon Holdings Inc
ZYME / Zymeworks Inc. Call
ZYME / Zymeworks Inc. Put
GMDA / Gamida Cell Ltd.
EYPT / EyePoint Pharmaceuticals, Inc. Call
ADMA / ADMA Biologics, Inc.
110122157 / Bristol Meyers Squibb CVR Exp. 12/31/2020
CLDX / Celldex Therapeutics, Inc.
CLDX / Celldex Therapeutics, Inc. Call
CARA / Cara Therapeutics, Inc. Call
AGEN / Agenus Inc.
MYOV / Myovant Sciences Ltd Call
STRO / Sutro Biopharma, Inc.
TNGX / Tango Therapeutics, Inc.
BEAM / Beam Therapeutics Inc. Put
IONS / Ionis Pharmaceuticals, Inc. Call
SYRS / Syros Pharmaceuticals, Inc.
TCRR / Tcr2 Therapeutics Inc
US28249H1041 / Eidos Therapeutics, Inc.
RPTX / Repare Therapeutics Inc.
EIGR / Eiger BioPharmaceuticals, Inc.
AL / Air Lease Corporation Put
ZYME / Zymeworks Inc.
/ Immunomedics, Inc. Call
MEOBF / Mesoblast Limited Put
ONCT / Oncternal Therapeutics, Inc.
0HBB / Aimmune Therapeutics Inc Put
ASLN / ASLAN Pharmaceuticals Limited - Depositary Receipt (Common Stock)
MRTX / Mirati Therapeutics, Inc. Put
ACAD / ACADIA Pharmaceuticals Inc. Put
DBVT / DBV Technologies S.A. - Depositary Receipt (Common Stock)
IGMS / IGM Biosciences, Inc. Call
IVA / Inventiva S.A. - Depositary Receipt (Common Stock)
QDEL / QuidelOrtho Corporation Call
ADVM / Adverum Biotechnologies, Inc. Put
BLUE / bluebird bio, Inc.
ACRS / Aclaris Therapeutics, Inc. Call
GMTX / Gemini Therapeutics Inc
BMY / Bristol-Myers Squibb Company Call
SRRK / Scholar Rock Holding Corporation
KALV / KalVista Pharmaceuticals, Inc.
KALV / KalVista Pharmaceuticals, Inc. Call
TGTX / TG Therapeutics, Inc. Put
DCTH / Delcath Systems, Inc.
CYTK / Cytokinetics, Incorporated Call
SRPT / Sarepta Therapeutics, Inc. Put
BMY / Bristol-Myers Squibb Company
FIXX / Homology Medicines, Inc. Put
AGIO / Agios Pharmaceuticals, Inc. Call
INMB / INmune Bio, Inc.
ARKG / ARK ETF Trust - ARK Genomic Revolution ETF Put
APTX / Aptinyx Inc.
PASG / Passage Bio, Inc.
MCRB / Seres Therapeutics, Inc. Call
MCRB / Seres Therapeutics, Inc.
AADI / Aadi Bioscience, Inc.
CLVS / Clovis Oncology Inc
APLT / Applied Therapeutics, Inc. Put
CRIS / Curis, Inc.
CRIS / Curis, Inc. Call
ACET / Adicet Bio, Inc.
CCXI / ChemoCentryx Inc
OTIC / Otonomy Inc
BPMC / Blueprint Medicines Corporation Put
LQDA / Liquidia Corporation
DRNA / Dicerna Pharmaceuticals Inc Put
VINC / Vincerx Pharma, Inc.
DRNA / Dicerna Pharmaceuticals Inc Call
KALA / KALA BIO, Inc.
CCXI / ChemoCentryx Inc Put
APLT / Applied Therapeutics, Inc.
AVTX / Avalo Therapeutics, Inc.
YMTX / Yumanity Therapeutics Inc
ACAD / ACADIA Pharmaceuticals Inc.
BLCM / Bellicum Pharmaceuticals, Inc.
CGEN / Compugen Ltd. Put
ICAD / iCAD, Inc.
CRTX / Cortexyme Inc
VTGN / Vistagen Therapeutics, Inc.
CARA / Cara Therapeutics, Inc.
MRTX / Mirati Therapeutics, Inc. Call
ARNA / Arena Pharmaceuticals Inc Call
PBYI / Puma Biotechnology, Inc.
AGTC / Applied Genetic Technologies Corp
CASI / CASI Pharmaceuticals, Inc.
FATE / Fate Therapeutics, Inc. Put
FATE / Fate Therapeutics, Inc. Call
INBX / Inhibrx Biosciences, Inc.
ARNA / Arena Pharmaceuticals Inc
BLUE / bluebird bio, Inc. Call
CLOV / Clover Health Investments, Corp.
ZGNX / Zogenix Inc Call
UTHR / United Therapeutics Corporation Call
BIIB / Biogen Inc. Call
MPW / Medical Properties Trust, Inc. Put
ZGNX / Zogenix Inc
TPST / Tempest Therapeutics, Inc.
LSAQ / LifeSci Acquisition II Corp
AVDL / Avadel Pharmaceuticals plc
CCXI / ChemoCentryx Inc Call
GILD / Gilead Sciences, Inc. Call
CRTX / Cortexyme Inc Put
CRTX / Cortexyme Inc Call
IFRX / InflaRx N.V.
IGMS / IGM Biosciences, Inc.
PRAX / Praxis Precision Medicines, Inc.
TRIL / Trillium Therapeutics Inc Call
KNTE / Kinnate Biopharma Inc.
OCUL / Ocular Therapeutix, Inc. Call
ARVN / Arvinas, Inc.
NVAX / Novavax, Inc. Put
NVAX / Novavax, Inc.
0UI8 / Aptose Biosciences Inc.
GBT / Global Blood Therapeutics Inc. Call
PHAT / Phathom Pharmaceuticals, Inc.
PBYI / Puma Biotechnology, Inc. Call
SAGE / Sage Therapeutics, Inc. Call
ASMB / Assembly Biosciences, Inc.
AUPH / Aurinia Pharmaceuticals Inc. Call
BLSA / BCLS Acquisition Corp - Class A
OVID / Ovid Therapeutics Inc. Call
NXTC / NextCure, Inc.
SRRA / Sierra Oncology Inc
CRBP / Corbus Pharmaceuticals Holdings, Inc.
RIGL / Rigel Pharmaceuticals, Inc.
CRBP / Corbus Pharmaceuticals Holdings, Inc. Call
DMAC / DiaMedica Therapeutics Inc.
BNTX / BioNTech SE - Depositary Receipt (Common Stock) Put
SNDX / Syndax Pharmaceuticals, Inc. Call
MRUS / Merus N.V.
DCPH / Deciphera Pharmaceuticals, Inc. Put
BLU / Bellus Health Inc
GOSS / Gossamer Bio, Inc.
GOSS / Gossamer Bio, Inc. Call
BTAI / BioXcel Therapeutics, Inc. Call
NKTR / Nektar Therapeutics Call
IMVT / Immunovant, Inc.
BHVN / Biohaven Ltd. Put
ARVN / Arvinas, Inc. Put
OCUL / Ocular Therapeutix, Inc.
MRSN / Mersana Therapeutics, Inc.
BIIB / Biogen Inc. Put
HZNP / Horizon Therapeutics Plc
HZNP / Horizon Therapeutics Plc Call
HZNP / Horizon Therapeutics Plc Put
LIFE / aTyr Pharma, Inc.
MRNA / Moderna, Inc. Put
LLY / Eli Lilly and Company Call
CYCC / Bio Green Med Solution, Inc.
MDGL / Madrigal Pharmaceuticals, Inc.
ATXS / Astria Therapeutics, Inc.
FGEN / FibroGen, Inc. Call
CVAC / CureVac N.V. Put
VSTM / Verastem, Inc.
BXRX / Baudax Bio, Inc.
ARWR / Arrowhead Pharmaceuticals, Inc. Call
ARDX / Ardelyx, Inc.
KNSA / Kiniksa Pharmaceuticals, Ltd.
KURA / Kura Oncology, Inc.
KURA / Kura Oncology, Inc. Call
BCLI / Brainstorm Cell Therapeutics Inc. Put
XBI / SPDR Series Trust - SPDR S&P Biotech ETF Put
VIRX / Viracta Therapeutics, Inc.
TCON / TRACON Pharmaceuticals, Inc.
CLVS / Clovis Oncology Inc Call
FGEN / FibroGen, Inc. Put
SLDB / Solid Biosciences Inc.
MORF / Morphic Holding, Inc.
ITCI / Intra-Cellular Therapies, Inc. Call
ACHV / Achieve Life Sciences, Inc.
SCPH / scPharmaceuticals Inc.
KPTI / Karyopharm Therapeutics Inc.
BIIB / Biogen Inc.
CYTK / Cytokinetics, Incorporated Put
CRDF / Cardiff Oncology, Inc. Put
ACRS / Aclaris Therapeutics, Inc.
VIR / Vir Biotechnology, Inc. Put
ANAB / AnaptysBio, Inc.
CRSP / CRISPR Therapeutics AG Put
ANAB / AnaptysBio, Inc. Call
MREO / Mereo BioPharma Group plc - Depositary Receipt (Common Stock)
ALLK / Allakos Inc. Call
AVRO / AVROBIO, Inc.
ARVN / Arvinas, Inc. Call
BHVN / Biohaven Ltd. Call
CMPS / COMPASS Pathways plc - Depositary Receipt (Common Stock) Call
CRNX / Crinetics Pharmaceuticals, Inc.
BGNE / BeiGene, Ltd. - Depositary Receipt (Common Stock) Put
XENE / Xenon Pharmaceuticals Inc.
RAPT / RAPT Therapeutics, Inc. Put
ARCT / Arcturus Therapeutics Holdings Inc. Put
INCY / Incyte Corporation Call
KOD / Kodiak Sciences Inc. Put
SPY / SPDR S&P 500 ETF Put
ALNY / Alnylam Pharmaceuticals, Inc. Put
CMPS / COMPASS Pathways plc - Depositary Receipt (Common Stock)
RCKT / Rocket Pharmaceuticals, Inc.
IMTX / Immatics N.V.
XFOR / X4 Pharmaceuticals, Inc.
SNDX / Syndax Pharmaceuticals, Inc.
ALEC / Alector, Inc.
RCUS / Arcus Biosciences, Inc. Put
SRPT / Sarepta Therapeutics, Inc. Call
MRNA / Moderna, Inc.
FULC / Fulcrum Therapeutics, Inc.
CYTK / Cytokinetics, Incorporated
HROW / Harrow, Inc.
ALT / Altimmune, Inc.
MIST / Milestone Pharmaceuticals Inc.
LYRA / Lyra Therapeutics, Inc.
RAPT / RAPT Therapeutics, Inc. Call
COGT / Cogent Biosciences, Inc.