Investor Stonepine Capital Management, LLC
13D/G Filings

This page shows a list of all the recent 13D/G filings made by Stonepine Capital Management, LLC . Schedule 13D is commonly referred to as a “beneficial ownership report.” The term "beneficial owner" is defined under SEC rules. It includes any person who directly or indirectly shares voting power or investment power (the power to sell the security).

When a person or group of persons acquires beneficial ownership of more than 5% of a voting class of a company’s equity securities, they are required to file a Schedule 13D within ten days after the purchase. Click the link icon to see the full transaction history.

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Date Form Target Prev
Shares		 Current
Shares		 Change
(Percent)		 Ownership
(Percent)		 Change
(Percent)
2025-09-08 13G KZR / Kezar Life Sciences, Inc. 377,240
2025-08-13 13G/A AYTU / Aytu BioPharma, Inc. 626,862 906,063
2025-08-13 13G/A SRZN / Surrozen, Inc. 332,451 508,687
2025-08-06 13G VSTM / Verastem, Inc. 2,203,333 2,833,333
2025-05-14 13G/A SRZN / Surrozen, Inc. 244,658 332,451
2025-05-14 13G/A OPTN / OptiNose, Inc. 588,657 788,647
2025-05-14 13G/A INO / Inovio Pharmaceuticals, Inc. 1,916,666 1,434,997
2025-05-14 13G/A CALC / CalciMedica, Inc. 741,701 628,672
2025-05-14 13G/A APRE / Aprea Therapeutics, Inc. 286,395 239,416
2025-02-25 13G EDSA / Edesa Biotech, Inc. 693,551
2025-02-13 13G/A OPTN / OptiNose, Inc. 588,657
2025-02-13 13G/A VSTM / Verastem, Inc. 2,643,620 2,203,333
2025-02-13 13G/A APRE / Aprea Therapeutics, Inc. 365,436 286,395
2025-02-13 13G/A TELA / TELA Bio, Inc. 2,831,839 2,353,099
2024-12-23 13G INO / Inovio Pharmaceuticals, Inc. 1,916,666
2024-12-13 13G CALC / CalciMedica, Inc. 0 741,701
2024-11-20 13G OPTN / OptiNose, Inc. 8,174,631
2024-11-13 13G/A SRZN / Surrozen, Inc. 199,158 244,658
2024-11-13 13G/A VSTM / Verastem, Inc. 2,666,666 2,643,620
2024-11-13 13G/A EOLS / Evolus, Inc. 5,333,004 1,369,821
2024-11-13 13G/A AYTU / Aytu BioPharma, Inc. 565,484 626,862
2024-11-13 13G/A TENX / Tenax Therapeutics, Inc. 372,797 372,797
2024-11-13 13G/A KPRX / Kiora Pharmaceuticals, Inc. 2,409,058 307,229
2024-11-13 13G/A CALC / CalciMedica, Inc. 1,045,204 0
2024-11-13 13G/A RZLT / Rezolute, Inc. 2,768,656 0
2024-11-13 13G/A ALIM / Alimera Sciences, Inc. 5,373,732 0
2024-11-13 13G/A IOBT / IO Biotech, Inc. 3,641,345 0
2024-10-29 13G TELA / TELA Bio, Inc. 2,831,839
2024-10-10 13G APRE / Aprea Therapeutics, Inc. 365,436
2024-08-15 13G TENX / Tenax Therapeutics, Inc. 372,797
2024-07-29 13G VSTM / Verastem, Inc. 2,666,666
2024-04-19 13G SRZN / Surrozen, Inc. 199,158
2024-02-13 13G/A URGN / UroGen Pharma Ltd. 1,304,947 0
2024-02-13 13G/A XGN / Exagen Inc. 854,042 669,684
2024-02-13 13G/A XERS / Xeris Biopharma Holdings, Inc. 11,195,189 5,937,000
2024-02-13 13G/A THRD / Third Harmonic Bio, Inc. 2,152,968 0
2024-02-13 13G/A SCYX / SCYNEXIS, Inc. 2,777,877 1,355,186
2024-02-13 13G/A ATYR / aTyr Pharma, Inc. 4,743,162 482,258
2024-02-13 13G/A RZLT / Rezolute, Inc. 3,021,504 2,768,656
2024-02-13 13G/A IOBT / IO Biotech, Inc. 3,950,616 3,641,345
2024-02-13 13G/A GMDAQ / Gamida Cell Ltd. 9,854,158 3,000,000
2024-02-13 13G/A EOLS / Evolus, Inc. 4,187,447 5,333,004
2024-02-13 13G/A DCTH / Delcath Systems, Inc. 976,008 208,333
2024-02-13 13G/A AYTU / Aytu BioPharma, Inc. 563,842 565,484
2024-02-13 13G/A ALIM / Alimera Sciences, Inc. 5,377,711 5,373,732
2024-02-09 13G KPRX / Kiora Pharmaceuticals, Inc. 2,409,058
2024-01-31 13G CALC / CalciMedica, Inc. 1,045,204
2023-08-24 13G GMDAQ / Gamida Cell Ltd. 9,854,158
2023-08-16 13G IOBT / IO Biotech, Inc. 3,950,616
2023-08-10 13G ALIM / Alimera Sciences, Inc. 0 5,377,711
2023-06-26 13G DCTH / Delcath Systems, Inc. 976,008
2023-06-16 13G EOLS / Evolus, Inc. 4,187,447
2023-06-16 13G AYTU / Aytu BioPharma, Inc. 563,842
2023-06-09 13G SCYX / SCYNEXIS, Inc. 385,650 2,777,877
2023-05-01 13G ATYR / aTyr Pharma, Inc. 4,569,433 4,743,162
2023-04-13 13G CTIC / CTI BioPharma Corp 5,664,100 7,018,046
2023-02-17 13G/A ATYR / aTyr Pharma, Inc. 4,569,433
2023-02-13 13G/A XERS / Xeris Biopharma Holdings, Inc. 6,491,099 11,195,189
2023-02-13 13G/A XGN / Exagen Inc. 858,567 854,042
2023-02-13 13G/A URGN / UroGen Pharma Ltd. 1,196,908 1,304,947
2023-02-13 13G/A US20717E2000 / CONFORMIS INC 748,194
2023-02-13 13G/A ADMA / ADMA Biologics, Inc. 9,911,577 6,940,000
2023-02-13 13G/A APEN / Apollo Endosurgery Inc 2,655,129 4,351,088
2023-02-13 13G/A RZLT / Rezolute, Inc. 808,405 3,021,504
2023-02-13 13G/A OVID / Ovid Therapeutics Inc. 4,006,185 0
2023-02-13 13G/A CTIC / CTI BioPharma Corp 9,754,935 5,664,100
2023-02-13 13G/A US03217L1061 / Amryt Pharma PLC Sponsored ADR (United Kingdom) 30,348,875 31,666,195
2023-01-19 13G THRD / Third Harmonic Bio, Inc. 2,152,968
2022-12-01 13G URGN / UroGen Pharma Ltd. 1,196,908
2022-02-14 13G/A ADMA / ADMA Biologics, Inc. 9,972,877 9,911,577
2022-02-14 13G/A CTIC / CTI BioPharma Corp 8,148,420 9,754,935
2022-02-14 13G/A XGN / Exagen Inc. 833,537 858,567
2022-02-14 13G/A SCYX / SCYNEXIS, Inc. 1,530,650 385,650
2022-02-14 13G/A OVID / Ovid Therapeutics Inc. 3,500,000 4,006,185
2022-02-14 13G/A CBIO / Crescent Biopharma, Inc. 2,144,812 0
2022-02-14 13G/A YMTX / Yumanity Therapeutics Inc 643,620 0
2022-02-14 13G/A CFMS / Conformis Inc. 9,161,871 14,768,823
2022-02-14 13G/A RZLT / Rezolute, Inc. 789,326 808,405
2022-02-14 13G/A APEN / Apollo Endosurgery Inc 2,603,480 2,655,129
2022-02-14 13G/A ADMS / Adamas Pharmaceuticals Inc 3,408,849 0
2022-02-11 13G/A AGTC / Applied Genetic Technologies Corp 2,273,876 0
2022-02-11 13G/A AYTU / Aytu BioPharma, Inc. 1,398,776 0
2022-02-11 13G/A US03217L1061 / Amryt Pharma PLC Sponsored ADR (United Kingdom) 11,082,415 30,348,875
2022-02-11 13G/A DMAC / DiaMedica Therapeutics Inc. 1,150,259 1,394,929
2022-01-14 13G XERS / Xeris Biopharma Holdings, Inc. 6,491,099 6,491,099
2021-12-30 13G ADMA / ADMA Biologics, Inc. 9,972,877
2021-12-27 13G RZLT / Rezolute, Inc. 789,326 789,326
2021-12-27 13G XGN / Exagen Inc. 833,537 833,537
2021-11-19 13G YMTX / Yumanity Therapeutics Inc 643,620
2021-08-09 13G/A US16706W1027 / Chiasma Inc 6,770,000 0
2021-07-09 13G SBBP / Strongbridge Biopharma plc 3,566,964
2021-06-14 13G CFMS / Conformis Inc. 0 9,161,871
2021-05-14 13G/A US16706W1027 / Chiasma Inc 3,862,483 6,770,000
2021-04-29 13G OVID / Ovid Therapeutics Inc. 3,500,000
2021-03-18 13G US16706W1027 / Chiasma Inc 3,862,483 3,862,483
2021-03-18 13G US16706W1027 / Chiasma Inc 3,862,483 3,862,483
2021-03-02 13G ADMS / Adamas Pharmaceuticals Inc 3,408,849 3,408,849
2021-03-02 13G ADMS / Adamas Pharmaceuticals Inc 808,431 3,408,849
2021-02-19 13G/A CBIO / Crescent Biopharma, Inc. 834,449 2,144,812
2021-02-12 13G/A ADMS / Adamas Pharmaceuticals Inc 2,241,239 808,431
2021-02-12 13G/A AYTU / Aytu BioPharma, Inc. 1,333,334 1,398,776
2021-02-12 13G/A HTGM / HTG Molecular Diagnostics Inc 5,913,812 0
2021-02-12 13G/A IDXG / Interpace Biosciences, Inc. 277,277 0
2021-02-12 13G/A OPNT / Opiant Pharmaceuticals Inc 334,272 0
2021-02-12 13G/A SCYX / SCYNEXIS, Inc. 1,536,953 1,530,650
2021-02-12 13G/A APVO / Aptevo Therapeutics Inc. 4,561,605 18,280
2021-02-12 13G/A US64052L1061 / Neos Therapeutics, Inc. 4,858,889 4,962,657
2021-02-12 13G/A ISEE / IVERIC bio Inc 5,147,744 800,000
2021-02-12 13G/A DMAC / DiaMedica Therapeutics Inc. 800,000 1,150,259
2021-02-12 13G/A CDTX / Cidara Therapeutics, Inc. 2,054,048 0
2021-02-12 13G/A CPIX / Cumberland Pharmaceuticals Inc. 896,170 188,703
2021-02-12 13G/A CBIO / Crescent Biopharma, Inc. 1,039,235 834,449
2021-02-12 13G/A BXRX / Baudax Bio, Inc. 1,819,849 0
2021-02-12 13G/A AFMD / Affimed N.V. 4,010,155 219,340
2021-02-12 13G/A APEN / Apollo Endosurgery Inc 2,141,279 2,603,480
2021-02-12 13G/A US03217L1061 / Amryt Pharma PLC Sponsored ADR (United Kingdom) 11,082,415
2021-02-12 13G/A CTIC / CTI BioPharma Corp 3,613,600 8,148,420
2021-02-08 13G AGTC / Applied Genetic Technologies Corp 2,273,876 2,273,876
2021-02-08 13G AGTC / Applied Genetic Technologies Corp 2,273,876 2,273,876
2020-12-23 13G SCYX / SCYNEXIS, Inc. 568,450 1,536,953
2020-12-17 13G AYTU / Aytu BioPharma, Inc. 1,333,334 1,333,334
2020-12-17 13G AYTU / Aytu BioPharma, Inc. 1,333,334 1,333,334
2020-09-11 13G IDXG / Interpace Biosciences, Inc. 107,760 277,277
2020-08-05 13G CBIO / Crescent Biopharma, Inc. 1,039,235 1,039,235
2020-04-17 13G IDXG / Interpace Biosciences, Inc. 107,760
2020-04-02 13G BXRX / Baudax Bio, Inc. 1,819,849
2020-03-12 13G CBIO / Crescent Biopharma, Inc. 1,039,235
2020-02-21 13G CDTX / Cidara Therapeutics, Inc. 2,054,048
2020-02-13 13G/A BDSI / Biodelivery Sciences International 3,981,867 0
2020-02-13 13G/A ATXS / Astria Therapeutics, Inc. 758,333 390,000
2020-02-13 13G/A CTIC / CTI BioPharma Corp 5,726,579 3,613,600
2020-02-13 13G/A CPIX / Cumberland Pharmaceuticals Inc. 1,313,429 896,170
2020-02-13 13G/A HTGM / HTG Molecular Diagnostics Inc 2,675,889 5,913,812
2020-02-13 13G/A US64052L1061 / Neos Therapeutics, Inc. 4,210,153 4,858,889
2020-02-13 13G/A NVLN / NOVELION THERAPEUTICS INC. 3,703,420 3,909,207
2020-02-13 13G/A OPNT / Opiant Pharmaceuticals Inc 357,960 334,272
2020-02-13 13G/A ISEE / IVERIC bio Inc 5,147,744
2020-02-13 13G/A AFMD / Affimed N.V. 4,593,022 4,010,155
2020-02-13 13G/A APEN / Apollo Endosurgery Inc 2,580,518 2,141,279
2020-02-13 13G/A APVO / Aptevo Therapeutics Inc. 4,273,862 4,561,605
2020-02-13 13G/A ALIM / Alimera Sciences, Inc. 6,547,774 0
2020-02-13 13G/A ADMS / Adamas Pharmaceuticals Inc 1,515,552 2,241,239
2020-02-12 13G DMAC / DiaMedica Therapeutics Inc. 800,000 800,000
2020-02-11 13G DMAC / DiaMedica Therapeutics Inc. 800,000
2019-12-16 13G AFMD / Affimed N.V. 4,593,022 4,593,022
2019-12-13 13G AFMD / Affimed N.V. 4,593,022
2019-10-02 13G/A NVLN / NOVELION THERAPEUTICS INC. 1,155,085 3,703,420
2019-08-23 13G NVLN / NOVELION THERAPEUTICS INC. 531,662 1,155,085
2019-07-23 13D/A VIVE / Viveve Medical, Inc. 3,907,513 57,802
2019-06-19 13G ADMS / Adamas Pharmaceuticals Inc 1,515,552
2019-03-18 13G APVO / Aptevo Therapeutics Inc. 4,273,862
2019-02-14 13G/A APEN / Apollo Endosurgery Inc 2,560,314 2,580,518
2019-02-13 13G/A BDSI / Biodelivery Sciences International 3,981,867 3,981,867
2019-02-13 13G/A ALIM / Alimera Sciences, Inc. 3,559,899 6,547,774
2019-02-13 13G/A CEMP / Cempra, Inc. 3,474,761 0
2019-02-13 13G/A US0909311062 / BioSpecifics Technologies Corp. 385,954 217,395
2019-02-13 13G/A NVLN / NOVELION THERAPEUTICS INC. 1,694,717 531,662
2019-02-13 13G/A US64052L1061 / Neos Therapeutics, Inc. 4,637,169 4,210,153
2019-02-13 13G/A ATEC / Alphatec Holdings, Inc. 1,733,534 1,147,802
2019-02-13 13G/A VYNT / Vyant Bio, Inc. 1,786,063 0
2019-02-13 13G/A HTGM / HTG Molecular Diagnostics Inc 1,450,000 2,675,889
2019-02-13 13G/A CFMS / Conformis Inc. 3,357,803 0
2019-02-13 13G/A ATXS / Astria Therapeutics, Inc. 4,800,000 758,333
2019-02-13 13G/A CORV / Correvio Pharma Corp. (Canada) 424,101
2019-02-13 13G/A SCYX / SCYNEXIS, Inc. 2,923,987 568,450
2019-02-13 13G/A CTIC / CTI BioPharma Corp 2,150,000 5,726,579
2019-02-13 13G/A OPNT / Opiant Pharmaceuticals Inc 199,368 357,960
2019-02-13 13G/A ISEE / IVERIC bio Inc 2,350,000 4,072,301
2019-02-13 13G/A CPIX / Cumberland Pharmaceuticals Inc. 1,306,911 1,313,429
2019-02-12 13G/A BDSI / Biodelivery Sciences International 3,645,491 3,981,867
2018-12-11 13D/A VIVE / Viveve Medical, Inc. 3,905,101 3,907,513
2018-11-08 13G US64052L1061 / Neos Therapeutics, Inc. 4,637,169
2018-11-02 13G CEMP / Cempra, Inc. 3,474,761
2018-10-25 13G SCYX / SCYNEXIS, Inc. 2,923,987
2018-10-09 13G OPNT / Opiant Pharmaceuticals Inc 199,368
2018-09-14 13D/A VIVE / Viveve Medical, Inc. 3,873,567 3,905,101
2018-06-28 13G ATXS / Astria Therapeutics, Inc. 4,800,000
2018-06-15 13G ATEC / Alphatec Holdings, Inc. 1,733,534
2018-05-11 13G STDY / SteadyMed Ltd. 1,381,651
2018-03-21 13G/A REPH / Societal CDMO Inc 1,050,115 94,182
2018-02-13 13G/A ALIM / Alimera Sciences, Inc. 4,615,813 3,559,899
2018-02-13 13G/A APEN / Apollo Endosurgery Inc 2,364,707 2,560,314
2018-02-13 13G/A BDSI / Biodelivery Sciences International 3,228,493 3,645,491
2018-02-13 13G/A US0909311062 / BioSpecifics Technologies Corp. 375,000 385,954
2018-02-13 13G/A VYNT / Vyant Bio, Inc. 1,396,205 1,786,063
2018-02-13 13G/A CRME / Cardiome Pharma Corp. 3,158,816 3,195,692
2018-02-13 13G/A CBMX / CombiMatrix Corp. 290,000 0
2018-02-13 13G/A CPIX / Cumberland Pharmaceuticals Inc. 1,083,469 1,306,911
2018-02-13 13G/A NVLN / NOVELION THERAPEUTICS INC. 1,644,591 1,694,717
2018-02-13 13G/A ISEE / IVERIC bio Inc 2,292,900 2,350,000
2018-02-13 13G/A REPH / Societal CDMO Inc 1,902,380 1,050,115
2018-02-13 13G/A VCEL / Vericel Corporation 1,883,800 0
2018-02-13 13G/A BBI / Brickell Biotech Inc 1,232,893 676,232
2018-02-12 13D/A VIVE / Viveve Medical, Inc. 3,858,209 3,873,567
2018-02-09 13G CFMS / Conformis Inc. 3,357,803
2018-01-22 13G HTGM / HTG Molecular Diagnostics Inc 1,450,000
2018-01-12 13G/A CTIC / CTI BioPharma Corp 2,150,000 2,150,000
2018-01-11 13G/A CTIC / CTI BioPharma Corp 2,307,446 2,150,000
2017-12-21 13G VYNT / Vyant Bio, Inc. 1,396,205
2017-12-18 13G US0909311062 / BioSpecifics Technologies Corp. 375,000
2017-11-15 13G BBI / Brickell Biotech Inc 1,232,893 1,232,893
2017-11-14 13G BBI / Brickell Biotech Inc 1,232,893
2017-08-18 13G APEN / Apollo Endosurgery Inc 2,364,707
2017-08-09 13G CBMX / CombiMatrix Corp. 290,000
2017-06-22 13G CTIC / CTI BioPharma Corp 2,307,446
2017-05-19 13D/A VIVE / Viveve Medical, Inc. 3,856,046 3,858,209
2017-05-19 13G CPIX / Cumberland Pharmaceuticals Inc. 1,083,469
2017-05-16 13G/A REPH / Societal CDMO Inc 1,902,380 1,902,380
2017-05-15 13G/A REPH / Societal CDMO Inc 2,874,317 1,902,380
2017-03-23 13D/A VIVE / Viveve Medical, Inc. 3,856,046
2017-02-14 13G/A NVLN / NOVELION THERAPEUTICS INC. 1,644,591
2017-02-14 13G/A ALIM / Alimera Sciences, Inc. 4,615,813
2017-02-14 13G/A CRME / Cardiome Pharma Corp. 3,158,816
2017-02-14 13G/A QLTI / The 2023 ETF Series Trust II - GMO International Quality ETF 1,644,591
2017-02-14 13G/A SAVA / Cassava Sciences, Inc. 0
2017-02-14 13G/A PTX / Pernix Therapeutics Holdings, Inc. 0
2017-02-14 13G/A TRIB / Trinity Biotech plc - Depositary Receipt (Common Stock) 436,066
2017-02-14 13G/A VCEL / Vericel Corporation 1,883,800
2017-01-13 13G BDSI / Biodelivery Sciences International 3,228,493
2016-12-29 13G ISEE / IVERIC bio Inc 2,292,900
2016-12-19 13G/A REPH / Societal CDMO Inc 2,874,317
2016-01-26 13G/A VNDA / Vanda Pharmaceuticals Inc. 2,321,556 2,017,900
2015-07-02 13G VNDA / Vanda Pharmaceuticals Inc. 2,321,556